Molecular Docking and High-Throughput Screening for Novel Inhibitors of Protein Tyrosine Phosphatase-1B von Doman, Thompson N, McGovern, Susan L, Witherbee, Bryan J, Kasten, Thomas P, Kurumbail, Ravi, Stallings, William C, Connolly, Daniel T, Shoichet, Brian K

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The role of the GPR91 ligand succinate in hematopoiesis von Hakak, Yaron, Lehmann‐Bruinsma, Karin, Phillips, Shirley, Le, Thuy, Liaw, Chen, Connolly, Daniel T., Behan, Dominic P.

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Nicotinic Acid Receptor Agonists Differentially Activate Downstream Effectors von Richman, Jeremy G., Kanemitsu-Parks, Martha, Gaidarov, Ibragim, Cameron, Jill S., Griffin, Peter, Zheng, Hong, Guerra, Nuvia C., Cham, Linda, Maciejewski-Lenoir, Dominique, Behan, Dominic P., Boatman, Doug, Chen, Ruoping, Skinner, Philip, Ornelas, Pricilla, Waters, M. Gerard, Wright, Samuel D., Semple, Graeme, Connolly, Daniel T.

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1-Alkyl-benzotriazole-5-carboxylic Acids Are Highly Selective Agonists of the Human Orphan G-Protein-Coupled Receptor GPR109b von Semple, Graeme, Skinner, Philip J, Cherrier, Martin C, Webb, Peter J, Sage, Carleton R, Tamura, Susan Y, Chen, Ruoping, Richman, Jeremy G, Connolly, Daniel T

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APD791, 3-Methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide, a Novel 5-Hydroxytryptamine 2A Receptor Antagonist: Pharmacological Profile, Pharmacokinet... von Adams, John W, Ramirez, Juan, Shi, Yunqing, Thomsen, William, Frazer, John, Morgan, Michael, Edwards, Jeffrey E, Chen, Weichao, Teegarden, Bradley R, Xiong, Yifeng, Al-Shamma, Hussien, Behan, Dominic P, Connolly, Daniel T

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Effects of a niacin receptor partial agonist, MK-0354, on plasma free fatty acids, lipids, and cutaneous flushing in humans von Lai, Eseng, MD, PhD, Waters, M. Gerard, PhD, Tata, James R., PhD, Radziszewski, Waldemar, MD, PhD, Perevozskaya, Inna, PhD, Zheng, Wei, MS, Wenning, Larissa, PhD, Connolly, Daniel T., PhD, Semple, Graeme, PhD, Johnson-Levonas, Amy O., PhD, Wagner, John A., MD, Mitchel, Yale, MD, Paolini, John F., MD, PhD

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Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a von Skinner, Philip J., Cherrier, Martin C., Webb, Peter J., Shin, Young-Jun, Gharbaoui, Tawfik, Lindstrom, Andrew, Hong, Vu, Tamura, Susan Y., Dang, Huong T., Pride, Cameron C., Chen, Ruoping, Richman, Jeremy G., Connolly, Daniel T., Semple, Graeme

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Vascular Permeability Factor, an Endothelial Cell Mitogen Related to PDGF von Keck, Pamela J., Hauser, Scott D., Krivi, Gwen, Sanzo, Kim, Warren, Thomas, Feder, Joseph, Connolly, Daniel T.

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Inhibition of Mas G-protein signaling improves coronary blood flow, reduces myocardial infarct size, and provides long-term cardioprotection von Zhang, Tong, Li, Zhuangjie, Dang, Huong, Chen, Ruoping, Liaw, Chen, Tran, Thuy-Anh, Boatman, P Douglas, Connolly, Daniel T, Adams, John W

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(1aR,5aR)1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic Acid (MK-1903): A Potent GPR109a Agonist that Lowers Free Fatty Acids in Humans von Boatman, P. Douglas, Lauring, Brett, Schrader, Thomas O, Kasem, Michelle, Johnson, Benjamin R, Skinner, Philip, Jung, Jae-Kyu, Xu, Jerry, Cherrier, Martin C, Webb, Peter J, Semple, Graeme, Sage, Carleton R, Knudsen, Jens, Chen, Ruoping, Luo, Wen-Lin, Caro, Luzelena, Cote, Josee, Lai, Eseng, Wagner, John, Taggart, Andrew K, Carballo-Jane, Ester, Hammond, Milton, Colletti, Steven L, Tata, James R, Connolly, Daniel T, Waters, M. Gerard, Richman, Jeremy G

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3-(1H-Tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): A Partial Agonist of the Nicotinic Acid Receptor, G-Protein Coupled Receptor 109a, with Antilipolytic but No V... von Semple, Graeme, Skinner, Philip J, Gharbaoui, Tawfik, Shin, Young-Jun, Jung, Jae-Kyu, Cherrier, Martin C, Webb, Peter J, Tamura, Susan Y, Boatman, P. Douglas, Sage, Carleton R, Schrader, Thomas O, Chen, Ruoping, Colletti, Steven L, Tata, James R, Waters, M. Gerard, Cheng, Kang, Taggart, Andrew K, Cai, Tian-Quan, Carballo-Jane, Ester, Behan, Dominic P, Connolly, Daniel T, Richman, Jeremy G

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Sequence polymorphisms provide a common consensus sequence for GPR41 and GPR42 von Liaw, Chen W, Connolly, Daniel T

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Inhibition of cholesteryl ester transfer protein by substituted dithiobisnicotinic acid dimethyl ester: involvement Of a critical cysteine von Hope, H R, Heuvelman, D, Duffin, K, Smith, C, Zablocki, J, Schilling, R, Hegde, S, Lee, L, Witherbee, B, Baganoff, M, Bruce, C, Tall, A R, Krul, E, Glenn, K, Connolly, D T

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Analogues of Acifran:  Agonists of the High and Low Affinity Niacin Receptors, GPR109a and GPR109b von Jung, Jae-Kyu, Johnson, Benjamin R, Duong, Tracy, Decaire, Marc, Uy, Jane, Gharbaoui, Tawfik, Boatman, P. Douglas, Sage, Carleton R, Chen, Ruoping, Richman, Jeremy G, Connolly, Daniel T, Semple, Graeme

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Vascular permeability factor: A unique regulator of blood vessel function von Connolly, Daniel T.

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5-N,N-Disubstituted 5-aminopyrazole-3-carboxylic acids are highly potent agonists of GPR109b von Skinner, Philip J., Webb, Peter J., Sage, Carleton R, Dang, Huong T., Pride, Cameron C., Chen, Ruoping, Tamura, Susan Y., Richman, Jeremy G., Connolly, Daniel T., Semple, Graeme

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Discovery and Structure−Activity Relationship of 3-Methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): A Highly Selective 5-Hydroxytryptamine2A... von Xiong, Yifeng, Teegarden, Bradley R, Choi, Jin-Sun Karoline, Strah-Pleynet, Sonja, Decaire, Marc, Jayakumar, Honnappa, Dosa, Peter I, Casper, Martin D, Pham, Lan, Feichtinger, Konrad, Ullman, Brett, Adams, John, Yuskin, Diane, Frazer, John, Morgan, Michael, Sadeque, Abu, Chen, Weichao, Webb, Robert R, Connolly, Daniel T, Semple, Graeme, Al-Shamma, Hussien

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Anti-thrombotic and vascular effects of AR246686, a novel 5-HT2A receptor antagonist von ADAMS, John W, RAMIREZ, Juan, BEHAN, Dominic P, CONNOLLY, Daniel T, ORTUNO, Danny, YUNQING SHI, THOMSEN, William, RICHMAN, Jeremy G, MORGAN, Michael, DOSA, Peter, TEEGARDEN, Bradley R, AL-SHAMMA, Hussien

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3-Nitro-4-amino benzoic acids and 6-amino nicotinic acids are highly selective agonists of GPR109b von Skinner, Philip J., Cherrier, Martin C., Webb, Peter J., Sage, Carleton R., Dang, Huong T., Pride, Cameron C., Chen, Ruoping, Tamura, Susan Y., Richman, Jeremy G., Connolly, Daniel T., Semple, Graeme

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Agonist lead identification for the high affinity niacin receptor GPR109a von Gharbaoui, Tawfik, Skinner, Philip J., Shin, Young-Jun, Averbuj, Claudia, Jung, Jae-Kyu, Johnson, Benjamin R., Duong, Tracy, Decaire, Marc, Uy, Jane, Cherrier, Martin C., Webb, Peter J., Tamura, Susan Y., Zou, Ning, Rodriguez, Nathalie, Boatman, P. Douglas, Sage, Carleton R., Lindstrom, Andrew, Xu, Jerry, Schrader, Thomas O., Smith, Brian M., Chen, Ruoping, Richman, Jeremy G., Connolly, Daniel T., Colletti, Steven L., Tata, James R., Semple, Graeme

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