Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation von Chen, Jun, Joshi, Shailen K., DiDomenico, Stanley, Perner, Richard J., Mikusa, Joe P., Gauvin, Donna M., Segreti, Jason A., Han, Ping, Zhang, Xu-Feng, Niforatos, Wende, Bianchi, Bruce R., Baker, Scott J., Zhong, Chengmin, Simler, Gricelda H., McDonald, Heath A., Schmidt, Robert G., McGaraughty, Steve P., Chu, Katharine L., Faltynek, Connie R., Kort, Michael E., Reilly, Regina M., Kym, Philip R.

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A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat von Jarvis, Michael F, Honore, Prisca, Shieh, Char-Chang, Chapman, Mark, Joshi, Shailen, Zhang, Xu-Feng, Kort, Michael, Carroll, William, Marron, Brian, Atkinson, Robert, Thomas, James, Liu, Dong, Krambis, Michael, Liu, Yi, McGaraughty, Steve, Chu, Katharine, Roeloffs, Rosemarie, Zhong, Chengmin, Mikusa, Joseph P, Hernandez, Gricelda, Gauvin, Donna, Wade, Carrie, Zhu, Chang, Pai, Madhavi, Scanio, Marc, Shi, Lei, Drizin, Irene, Gregg, Robert, Matulenko, Mark, Hakeem, Ahmed, Gross, Michael, Johnson, Matthew, Marsh, Kennan, Wagoner, P. Kay, Sullivan, James P, Faltynek, Connie R, Krafte, Douglas S

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Pore Dilation Occurs in TRPA1 but Not in TRPM8 Channels von Chen, Jun, Kim, Donghee, Bianchi, Bruce R, Cavanaugh, Eric J, Faltynek, Connie R, Kym, Philip R, Reilly, Regina M

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Transient receptor potential A1 mediates an osmotically activated ion channel von Zhang, Xu-Feng, Chen, Jun, Faltynek, Connie R., Moreland, Robert B., Neelands, Torben R.

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Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia von Honore, Prisca, Chandran, Prasant, Hernandez, Gricelda, Gauvin, Donna M., Mikusa, Joseph P., Zhong, Chengmin, Joshi, Shailen K., Ghilardi, Joseph R., Sevcik, Molly A., Fryer, Ryan M., Segreti, Jason A., Banfor, Patricia N., Marsh, Kennan, Neelands, Torben, Bayburt, Erol, Daanen, Jerome F., Gomtsyan, Arthur, Lee, Chih-Hung, Kort, Michael E., Reilly, Regina M., Surowy, Carol S., Kym, Philip R., Mantyh, Patrick W., Sullivan, James P., Jarvis, Michael F., Faltynek, Connie R.

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Molecular Determinants of Species-Specific Activation or Blockade of TRPA1 Channels von Chen, Jun, Zhang, Xu-Feng, Kort, Michael E, Huth, Jeffrey R, Sun, Chaohong, Miesbauer, Laura J, Cassar, Steven C, Neelands, Torben, Scott, Victoria E, Moreland, Robert B, Reilly, Regina M, Hajduk, Philip J, Kym, Philip R, Hutchins, Charles W, Faltynek, Connie R

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Vanilloid receptor TRPV1 in drug discovery: targeting pain and other pathological disorders von Gomtsyan, Arthur, Faltynek, Connie R

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Analgesic profile of intrathecal P2X3 antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats von HONORE, Prisca, KAGE, Karen, MIKUSA, Joseph, WATT, Andrew T, JOHNSTON, Joseph F, WYATT, Jacqueline R, FALTYNEK, Connie R, JARVIS, Michael F, LYNCH, Kevin

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Quantification of TRPV1 Protein Levels in Rat Tissues to Understand its Physiological Roles von Han, Ping, Korepanova, Alla V., Vos, Melissa H., Moreland, Robert B., Chiu, Mark L., Faltynek, Connie R.

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Functional expression of P2X7 receptors in non-neuronal cells of rat dorsal root ganglia von ZHANG, Xu-Feng, PING HAN, FALTYNEK, Connie R, JARVIS, Michael F, SHIEH, Char-Chang

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Activation of TRPA1 Channels by the Fatty Acid Amide Hydrolase Inhibitor 3′-Carbamoylbiphenyl-3-yl cyclohexylcarbamate (URB597) von Niforatos, Wende, Zhang, Xu-Feng, Lake, Marc R., Walter, Karl A., Neelands, Torben, Holzman, Thomas F., Scott, Victoria E., Faltynek, Connie R., Moreland, Robert B., Chen, Jun

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TRPV1b overexpression negatively regulates TRPV1 responsiveness to capsaicin, heat and low pH in HEK293 cells von Vos, Melissa H., Neelands, Torben R., McDonald, Heath A., Choi, Won, Kroeger, Paul E., Puttfarcken, Pamela S., Faltynek, Connie R., Moreland, Robert B., Han, Ping

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Antagonism of TRPV1 receptors indirectly modulates activity of thermoregulatory neurons in the medial preoptic area of rats von McGaraughty, Steve, Segreti, Jason A, Fryer, Ryan M, Brown, Brian S, Faltynek, Connie R, Kym, Philip R

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Central Pituitary Adenylate Cyclase 1 Receptors Modulate Nociceptive Behaviors in Both Inflammatory and Neuropathic Pain States von Davis-Taber, Rachel, Baker, Scott, Lehto, Sonya G, Zhong, Chengmin, Surowy, Carol S, Faltynek, Connie R, Scott, Victoria E, Honore, Prisca

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Effects of A‐317491, a novel and selective P2X 3 /P2X 2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar admini... von McGaraughty, Steve, Wismer, Carol T, Zhu, Chang Z, Mikusa, Joseph, Honore, Prisca, Chu, Katharine L, Lee, Chih‐Hung, Faltynek, Connie R, Jarvis, Michael F

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Characterization of A-425619 at native TRPV1 receptors: A comparison between dorsal root ganglia and trigeminal ganglia von McDonald, Heath A., Neelands, Torben R., Kort, Michael, Han, Ping, Vos, Melissa H., Faltynek, Connie R., Moreland, Robert B., Puttfarcken, Pamela S.

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Structure−Activity Relationship Studies on a Series of Novel, Substituted 1-Benzyl-5-phenyltetrazole P2X7 Antagonists von Nelson, Derek W, Gregg, Robert J, Kort, Michael E, Perez-Medrano, Arturo, Voight, Eric A, Wang, Ying, Grayson, George, Namovic, Marian T, Donnelly-Roberts, Diana L, Niforatos, Wende, Honore, Prisca, Jarvis, Michael F, Faltynek, Connie R, Carroll, William A

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Differential action potentials and firing patterns in injured and uninjured small dorsal root ganglion neurons after nerve injury von Zhang, Xu-Feng, Zhu, Chang Z, Thimmapaya, Rama, Choi, Won S, Honore, Prisca, Scott, Victoria E, Kroeger, Paul E, Sullivan, James P, Faltynek, Connie R, Gopalakrishnan, Murali, Shieh, Char-Chang

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Pharmacology of Modality-Specific Transient Receptor Potential Vanilloid-1 Antagonists That Do Not Alter Body Temperature von Reilly, Regina M., McDonald, Heath A., Puttfarcken, Pamela S., Joshi, Shailen K., Lewis, LaGeisha, Pai, Madhavi, Franklin, Pamela H., Segreti, Jason A., Neelands, Torben R., Han, Ping, Chen, Jun, Mantyh, Patrick W., Ghilardi, Joseph R., Turner, Teresa M., Voight, Eric A., Daanen, Jerome F., Schmidt, Robert G., Gomtsyan, Arthur, Kort, Michael E., Faltynek, Connie R., Kym, Philip R.

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Modulation of human TRPV1 receptor activity by extracellular protons and host cell expression system von Bianchi, Bruce R., Lee, Chih-Hung, Jarvis, Michael F., El Kouhen, Rachid, Moreland, Robert B., Faltynek, Connie R., Puttfarcken, Pamela S.

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