Tau-targeting therapies for Alzheimer disease von Congdon, Erin E., Sigurdsson, Einar M.

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Sex Differences in Autophagy Contribute to Female Vulnerability in Alzheimer's Disease von Congdon, Erin E

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Tau-targeting therapies for Alzheimer disease: current status and future directions von Congdon, Erin E., Ji, Changyi, Tetlow, Amber M., Jiang, Yixiang, Sigurdsson, Einar M.

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Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo von Congdon, Erin E., Wu, Jessica W., Myeku, Natura, Figueroa, Yvette H., Herman, Mathieu, Marinec, Paul S., Gestwicki, Jason E., Dickey, Chad A., Yu, W. Haung, Duff, Karen E.

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Tau Isoform Composition Influences Rate and Extent of Filament Formation von Zhong, Qi, Congdon, Erin E., Nagaraja, Haikady N., Kuret, Jeff

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Increased neuronal activity in motor cortex reveals prominent calcium dyshomeostasis in tauopathy mice von Wu, Qian, Bai, Yang, Li, Wei, Congdon, Erin E., Liu, Wenke, Lin, Yan, Ji, Changyi, Gan, Wen-Biao, Sigurdsson, Einar M.

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Single-domain antibody-based protein degrader for synucleinopathies von Jiang, Yixiang, Lin, Yan, Tetlow, Amber M, Pan, Ruimin, Ji, Changyi, Kong, Xiang-Peng, Congdon, Erin E, Sigurdsson, Einar M

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Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden von O'Leary, 3rd, John C, Li, Qingyou, Marinec, Paul, Blair, Laura J, Congdon, Erin E, Johnson, Amelia G, Jinwal, Umesh K, Koren, 3rd, John, Jones, Jeffrey R, Kraft, Clara, Peters, Melinda, Abisambra, Jose F, Duff, Karen E, Weeber, Edwin J, Gestwicki, Jason E, Dickey, Chad A

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Dynamics of Internalization and Intracellular Interaction of Tau Antibodies and Human Pathological Tau Protein in a Human Neuron-Like Model von Shamir, Dov B., Deng, Yan, Wu, Qian, Modak, Swananda, Congdon, Erin E., Sigurdsson, Einar M.

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Single domain antibodies targeting pathological tau protein: Influence of four IgG subclasses on efficacy and toxicity von Congdon, Erin E., Pan, Ruimin, Jiang, Yixiang, Sandusky-Beltran, Leslie A., Dodge, Andie, Lin, Yan, Liu, Mengyu, Kuo, Min-Hao, Kong, Xiang-Peng, Sigurdsson, Einar M.

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Two Novel Tau Antibodies Targeting the 396/404 Region Are Primarily Taken Up by Neurons and Reduce Tau Protein Pathology von Gu, Jiaping, Congdon, Erin E., Sigurdsson, Einar M.

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Structure−Activity Relationship of Cyanine Tau Aggregation Inhibitors von Chang, Edward, Congdon, Erin E, Honson, Nicolette S, Duff, Karen E, Kuret, Jeff

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Targeting tau only extracellularly is likely to be less efficacious than targeting it both intra- and extracellularly von Congdon, Erin E., Jiang, Yixiang, Sigurdsson, Einar M.

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Antibody Uptake into Neurons Occurs Primarily via Clathrin-dependent Fcγ Receptor Endocytosis and Is a Prerequisite for Acute Tau Protein Clearance von Congdon, Erin E., Gu, Jiaping, Sait, Hameetha B.R., Sigurdsson, Einar M.

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Evaluating triggers and enhancers of tau fibrillization von Kuret, Jeff, Congdon, Erin E., Li, Guibin, Yin, Haishan, Yu, Xian, Zhong, Qi

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Inhibition of Tau Polymerization with a Cyanine Dye in Two Distinct Model Systems von Congdon, Erin E., Figueroa, Yvette H., Wang, Lili, Toneva, Galina, Chang, Edward, Kuret, Jeff, Conrad, Christopher, Duff, Karen E.

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Nucleation-dependent Tau Filament Formation: THE IMPORTANCE OF DIMERIZATION AND AN ESTIMATION OF ELEMENTARY RATE CONSTANTS von Congdon, Erin E, Kim, Sohee, Bonchak, Jonathan, Songrug, Tanakorn, Matzavinos, Anastasios, Kuret, Jeff

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Affinity of Tau antibodies for solubilized pathological Tau species but not their immunogen or insoluble Tau aggregates predicts in vivo and ex vivo efficacy von Congdon, Erin E, Lin, Yan, Rajamohamedsait, Hameetha B, Shamir, Dov B, Krishnaswamy, Senthilkumar, Rajamohamedsait, Wajitha J, Rasool, Suhail, Gonzalez, Veronica, Levenga, Josien, Gu, Jiaping, Hoeffer, Charles, Sigurdsson, Einar M

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Single-domain antibody-based noninvasive in vivo imaging of α-synuclein or tau pathology von Jiang, Yixiang, Lin, Yan, Krishnaswamy, Senthilkumar, Pan, Ruimin, Wu, Qian, Sandusky-Beltran, Leslie A, Liu, Mengyu, Kuo, Min-Hao, Kong, Xiang-Peng, Congdon, Erin E, Sigurdsson, Einar M

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Tau antibody chimerization alters its charge and binding, thereby reducing its cellular uptake and efficacy von Congdon, Erin E., Chukwu, Jessica E., Shamir, Dov B., Deng, Jingjing, Ujla, Devyani, Sait, Hameetha B.R., Neubert, Thomas A., Kong, Xiang-Peng, Sigurdsson, Einar M.

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