Application of CYP102A1M11H as a Tool for the Generation of Protein Adducts of Reactive Drug Metabolites von Boerma, J. S, Vermeulen, N. P. E, Commandeur, J. N. M

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Active Site Substitution A82W Improves the Regioselectivity of Steroid Hydroxylation by Cytochrome P450 BM3 Mutants As Rationalized by Spin Relaxation Nuclear Magnetic Resonance St... von Rea, V, Kolkman, A. J, Vottero, E, Stronks, E. J, Ampt, K. A. M, Honing, M, Vermeulen, N. P. E, Wijmenga, S. S, Commandeur, J. N. M

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Inhibition of human glutathione S-transferases by curcumin and analogues von Appiah-Opong, R., Commandeur, J. N. M., Istyastono, E., Bogaards, J. J., Vermeulen, N. P. E.

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Studies on the inhibition of human cytochromes P450 by selenocysteine Se -conjugates von Venhorst, J., Rooseboom, M., Vermeulen, N. P. E., Commandeur, J. N. M.

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Bioactivation of N-substituted N′-(4-imidazole-ethyl)thioureas by human FMO1 and FMO3 von Onderwater, R.C.A., Rettie, A.E., Commandeur, J.N.M., Vermeulen, N.P.E.

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Cytotoxicity and cytoprotective activities of natural compounds. The case of curcumin von Commandeur, J.N.M, Vermeulen, N.P.E

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Metabolism of N-substituted 7-methoxy-4-(aminomethyl) -coumarins by cytochrome P450 2D6 mutants and the indication of additional substrate interaction points von Keizers, P. H. J., Van Dijk, B. R., De Graaf, C., Van Vugt-Lussenburg, B. M. A., Vermeulen, N. P. E., Commandeur, J. N. M.

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Study on the cytochrome P-450- and glutathione-dependent biotransformation of trichloroethylene in humans von BLOEMEN, L. J, MONSTER, A. C, KEZIC, S, COMMANDEUR, J. N. M, VEULEMANS, H, VERMEULEN, N. P. E, WILMER, J. W

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Identification of N-acetyl(2,2-dichlorovinyl)- and N-acetyl(1,2-dichlorovinyl)L-cysteine as two regioisomeric mercapturic acids of trichloroethylene in the rat von Commandeur, J. N. M, Vermeulen, N. P. E

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Genetic Polymorphisms of Human N-Acetyltransferase, Cytochrome P450, Glutathione-S-Transferase, and Epoxide Hydrolase Enzymes: Relevance to Xenobiotic Metabolism and Toxicity von Wormhoudt, Lars W., Commandeur, Jan N. M., Vermeulen, Nico P. E.

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Uptake-toxicity relationships of a series of N-substituted N′-(4-imidazole-ethyl)thiourea in precision-cut rat liver slices von Onderwater, R. C. A., Commandeur, J. N. M., Rooseboom, M., Vermeulen, N. P. E.

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Allylmercapturic acid as urinary biomarker of human exposure to allyl chloride von de Rooij, B M, Boogaard, P J, Commandeur, J N, van Sittert, N J, Vermeulen, N P

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Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver von Oetari, S., Sudibyo, M., Commandeur, Jan N.M., Samhoedi, R., Vermeulen, Nico P.E.

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Urinary excretion of N-acetyl-S-allyl-L-cysteine upon garlic consumption by human volunteers von DE ROOIJ, B. M, BOOGAARD, P. J, RIJKSEN, D. A, COMMANDEUR, J. N. M, VERMEULEN, N. P. E

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Use of 19F-nuclear magnetic resonance and gas chromatography-electron capture detection in the quantitative analysis of fluorine-containing metabolites in urine of sevoflurane-anae... von Orhan, H., Commandeur, J. N. M., Sahin, G., Aypar, U., Sahin, A., Vermeulen, N. P. E.

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Synthesis of Novel Se-Substituted Selenocysteine Derivatives as Potential Kidney Selective Prodrugs of Biologically Active Selenol Compounds:  Evaluation of Kinetics of β-Eliminati... von Andreadou, Ioanna, Menge, Wiro M. P. B, Commandeur, Jan N. M, Worthington, Eduard A, Vermeulen, Nico P. E

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Disposition in rat of [2-3H]-trans-4-hydroxy-2,3-nonenal, a product of lipid peroxidation von De Zwart, L. L., Hermanns, R. C. A., Meerman, J. H. N., Commandeur, J. N. M., Vermeulen, N. P. E.

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Excretion of multiple urinary biomarkers for radical induced damage in rats treated with three different nephrotoxic compounds von DE ZWART, L. L, HERMANNS, R. C. A, MEERMAN, J. H. N, COMMANDEUR, J. N. M, SALEMINK, P. J. M, VERMEULEN, N. P. E

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Rat liver microsomal cytochrome P450-dependent oxidation of 3,5-disubstituted analogues of paracetamol von Bessems, J. G. M., Te Koppele, J. M., Van Dijk, P. A., Van Stee, L. L. P., Commandeur, J. N. M., Vermeulen, N. P. E.

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Enzyme kinetics and substrate selectivities of rat glutathione S-transferase isoenzymes towards a series of new 2-substituted 1-chloro-4-nitrobenzenes von van der Aar, E. M., Buikema, D., Commandeur, J. N. M., Te Koppele, J. M., van Ommen, B., Van Bladeren, P. J., Vermeulen, N. P. E.

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