DDRugging glioblastoma: understanding and targeting the DNA damage response to improve future therapies von Rominiyi, Ola, Collis, Spencer J.

Volltext

Low-Dose Hyper-Radiosensitivity: Past, Present, and Future von Marples, Brian, Ph.D, Collis, Spencer J., Ph.D

Volltext

Preventing Nonhomologous End Joining Suppresses DNA Repair Defects of Fanconi Anemia von Adamo, Adele, Collis, Spencer J., Adelman, Carrie A., Silva, Nicola, Horejsi, Zuzana, Ward, Jordan D., Martinez-Perez, Enrique, Boulton, Simon J., La Volpe, Adriana

Volltext

EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7 von O'Regan, Laura, Barone, Giancarlo, Adib, Rozita, Woo, Chang Gok, Jeong, Hui Jeong, Richardson, Emily L., Richards, Mark W., Muller, Patricia A. J., Collis, Spencer J., Fennell, Dean A., Choi, Jene, Bayliss, Richard, Fry, Andrew M.

Volltext

CK2 Phospho-Dependent Binding of R2TP Complex to TEL2 Is Essential for mTOR and SMG1 Stability von Hořejší, Zuzana, Takai, Hiroyuki, Adelman, Carrie A., Collis, Spencer J., Flynn, Helen, Maslen, Sarah, Skehel, J. Mark, de Lange, Titia, Boulton, Simon J.

Volltext

RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination von Barber, Louise J., Youds, Jillian L., Ward, Jordan D., McIlwraith, Michael J., O'Neil, Nigel J., Petalcorin, Mark I.R., Martin, Julie S., Collis, Spencer J., Cantor, Sharon B., Auclair, Melissa, Tissenbaum, Heidi, West, Stephen C., Rose, Ann M., Boulton, Simon J.

Volltext

Downregulation of homologous recombination DNA repair genes by HDAC inhibition in prostate cancer is mediated through the E2F1 transcription factor von Kachhap, Sushant K, Rosmus, Nadine, Collis, Spencer J, Kortenhorst, Madeleine S Q, Wissing, Michel D, Hedayati, Mohammad, Shabbeer, Shabana, Mendonca, Janet, Deangelis, Justin, Marchionni, Luigi, Lin, Jianqing, Höti, Naseruddin, Nortier, Johan W R, DeWeese, Theodore L, Hammers, Hans, Carducci, Michael A

Volltext

FANCM and FAAP24 Function in ATR-Mediated Checkpoint Signaling Independently of the Fanconi Anemia Core Complex von Collis, Spencer J., Ciccia, Alberto, Deans, Andrew J., Hořejší, Zuzana, Martin, Julie S., Maslen, Sarah L., Skehel, J. Mark, Elledge, Stephen J., West, Stephen C., Boulton, Simon J.

Volltext

The centriolar satellite protein Cep131 is important for genome stability von Staples, Christopher J, Myers, Katie N, Beveridge, Ryan D D, Patil, Abhijit A, Lee, Alvin J X, Swanton, Charles, Howell, Michael, Boulton, Simon J, Collis, Spencer J

Volltext

MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response von Staples, Christopher J., Barone, Giancarlo, Myers, Katie N., Ganesh, Anil, Gibbs-Seymour, Ian, Patil, Abhijit A., Beveridge, Ryan D., Daye, Caroline, Beniston, Richard, Maslen, Sarah, Ahel, Ivan, Skehel, J. Mark, Collis, Spencer J.

Volltext

Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability von Staples, Christopher J, Myers, Katie N, Beveridge, Ryan D D, Patil, Abhijit A, Howard, Anna E, Barone, Giancarlo, Lee, Alvin J X, Swanton, Charles, Howell, Michael, Maslen, Sarah, Skehel, J Mark, Boulton, Simon J, Collis, Spencer J

Volltext

Identification and Validation of ERK5 as a DNA Damage Modulating Drug Target in Glioblastoma von Carmell, Natasha, Rominiyi, Ola, Myers, Katie N., McGarrity-Cottrell, Connor, Vanderlinden, Aurelie, Lad, Nikita, Perroux-David, Eva, El-Khamisy, Sherif F., Fernando, Malee, Finegan, Katherine G., Brown, Stephen, Collis, Spencer J.

Volltext

DOG-1 Is the Caenorhabditis elegans BRIP1/FANCJ Homologue and Functions in Interstrand Cross-Link Repair von Youds, Jillian L., Barber, Louise J., Ward, Jordan D., Collis, Spencer J., O'Neil, Nigel J., Boulton, Simon J., Rose, Ann M.

Volltext

Ex-vivo drug screening of surgically resected glioma stem cells to replace murine avatars and provide personalise cancer therapy for glioblastoma patients [version 2; peer review:... von Gagg, Hannah, Williams, Sophie T., Conroy, Samantha, Myers, Katie N., McGarrity-Cottrell, Connor, Jones, Callum, Helleday, Thomas, Rantala, Juha, Rominiyi, Ola, Danson, Sarah J., Collis, Spencer J., Wells, Greg

Volltext

Ex-vivo drug screening of surgically resected glioma stem cells to replace murine avatars and provide personalise cancer therapy for glioblastoma patients [version 1; peer review:... von Gagg, Hannah, Williams, Sophie T., Conroy, Samantha, Myers, Katie N., McGarrity-Cottrell, Connor, Jones, Callum, Helleday, Thomas, Rantala, Juha, Rominiyi, Ola, Danson, Sarah J., Collis, Spencer J., Wells, Greg

Volltext

DNA damage response inhibitors enhance tumour treating fields (TTFields) potency in glioma stem-like cells von Vanderlinden, Aurelie, Jones, Callum G., Myers, Katie N., Rominiyi, Ola, Collis, Spencer J.

Volltext

Transition in Survival From Low-Dose Hyper-Radiosensitivity to Increased Radioresistance Is Independent of Activation of ATM SER1981 Activity von Krueger, Sarah A., Ph.D, Collis, Spencer J., Ph.D, Joiner, Michael C., Ph.D, Wilson, George D., Ph.D, Marples, Brian, Ph.D

Volltext

Evasion of Early Cellular Response Mechanisms following Low Level Radiation-induced DNA Damage von Collis, Spencer J., Schwaninger, Julie M., Ntambi, Alfred J., Keller, Thomas W., Nelson, William G., Dillehay, Larry E., DeWeese, Theodore L.

Volltext

Development and Optimisation of Tumour Treating Fields (TTFields) Delivery within 3D Primary Glioma Stem Cell-like Models of Spatial Heterogeneity von Jones, Callum G, Vanderlinden, Aurelie, Rominiyi, Ola, Collis, Spencer J

Volltext

Emerging links between the biological clock and the DNA damage response von Collis, Spencer J, Boulton, Simon J

Volltext