Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain von Croll, Tristan I., Smith, Brian J., Margetts, Mai B., Whittaker, Jonathan, Weiss, Michael A., Ward, Colin W., Lawrence, Michael C.

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Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors von Menting, John G., Lawrence, Callum F., Kong, Geoffrey K.-W., Margetts, Mai B., Ward, Colin W., Lawrence, Michael C.

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Protective hinge in insulin opens to enable its receptor engagement von Menting, John G, Yang, Yanwu, Chan, Shu Jin, Phillips, Nelson B, Smith, Brian J, Whittaker, Jonathan, Wickramasinghe, Nalinda P, Whittaker, Linda J, Pandyarajan, Vijay, Wan, Zhu-li, Yadav, Satya P, Carroll, Julie M, Strokes, Natalie, Roberts, Jr, Charles T, Ismail-Beigi, Faramarz, Milewski, Wieslawa, Steiner, Donald F, Chauhan, Virander S, Ward, Colin W, Weiss, Michael A, Lawrence, Michael C

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Insulin receptor structure and its implications for the IGF-1 receptor von Lawrence, Michael C, McKern, Neil M, Ward, Colin W

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Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists von Smith, Brian J, Huang, Kun, Kong, Geoffrey, Chan, Shu Jin, Nakagawa, Satoe, Menting, John G, Hu, Shi-Quan, Whittaker, Jonathan, Steiner, Donald F, Katsoyannis, Panayotis G, Ward, Colin W, Weiss, Michael A, Lawrence, Michael C

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Structural Determinants for High-Affinity Binding of Insulin-Like Growth Factor II to Insulin Receptor (IR)-A, the Exon 11 Minus Isoform of the IR von Denley, Adam, Bonython, Eric R, Booker, Grant W, Cosgrove, Leah J, Forbes, Briony E, Ward, Colin W, Wallace, John C

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The First Three Domains of the Insulin Receptor Differ Structurally from the Insulin-like Growth Factor 1 Receptor in the Regions Governing Ligand Specificity von Lou, Meizhen, Garrett, Thomas P. J., McKern, Neil M., Hoyne, Peter A., Epa, V. Chandana, Bentley, John D., Lovrecz, George O., Cosgrove, Leah J., Frenkel, Maurice J., Ward, Colin W.

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Is it time to retire the genus Rymovirus from the family Potyviridae? von Ward, Colin W.

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How insulin engages its primary binding site on the insulin receptor von Menting, John G., Whittaker, Jonathan, Margetts, Mai B., Whittaker, Linda J., Kong, Geoffrey K.-W., Smith, Brian J., Watson, Christopher J., Žáková, Lenka, Kletvíková, Emília, Jiráček, Jiří, Chan, Shu Jin, Steiner, Donald F., Dodson, Guy G., Brzozowski, Andrzej M., Weiss, Michael A., Ward, Colin W., Lawrence, Michael C.

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The insulin receptor changes conformation in unforeseen ways on ligand binding: Sharpening the picture of insulin receptor activation von Ward, Colin W., Menting, John G., Lawrence, Michael C.

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Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor von Ward, Colin W, Lawrence, Michael C

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Identification of the Epitope for the Epidermal Growth Factor Receptor-specific Monoclonal Antibody 806 Reveals That It Preferentially Recognizes an Untethered Form of the Receptor von Johns, Terrance G, Adams, Timothy E, Cochran, Jennifer R, Hall, Nathan E, Hoyne, Peter A, Olsen, Mark J, Kim, Yong-Sung, Rothacker, Julie, Nice, Edouard C, Walker, Francesca, Ritter, Gerd, Jungbluth, Achim A, Old, Lloyd J, Ward, Colin W, Burgess, Antony W, Wittrup, K Dane, Scott, Andrew M

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Epidermal growth factor receptor: mechanisms of activation and signalling von Jorissen, Robert N, Walker, Francesca, Pouliot, Normand, Garrett, Thomas P.J, Ward, Colin W, Burgess, Antony W

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Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor von Garrett, Thomas P. J, Bentley, John D, Ward, Colin W, McKern, Neil M, Lou, Meizhen, Frenkel, Maurice J, Lovrecz, George O, Elleman, Thomas C, Cosgrove, Leah J

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Similar but different: ligand-induced activation of the insulin and epidermal growth factor receptor families von Ward, Colin W, Lawrence, Michael C

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An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors von Burgess, Antony W, Cho, Hyun-Soo, Eigenbrot, Charles, Ferguson, Kathryn M, Garrett, Thomas P.J, Leahy, Daniel J, Lemmon, Mark A, Sliwkowski, Mark X, Ward, Colin W, Yokoyama, Shigeyuki

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Insulin Mimetic Peptide Disrupts the Primary Binding Site of the Insulin Receptor von Lawrence, Callum F., Margetts, Mai B., Menting, John G., Smith, Nicholas A., Smith, Brian J., Ward, Colin W., Lawrence, Michael C.

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A Designed Ankyrin Repeat Protein Evolved to Picomolar Affinity to Her2 von Zahnd, Christian, Wyler, Emanuel, Schwenk, Jochen M., Steiner, Daniel, Lawrence, Michael C., McKern, Neil M., Pecorari, Frédéric, Ward, Colin W., Joos, Thomas O., Plückthun, Andreas

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Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor α von Garrett, Thomas P.J., McKern, Neil M., Lou, Meizhen, Elleman, Thomas C., Adams, Timothy E., Lovrecz, George O., Zhu, Hong-Jian, Walker, Francesca, Frenkel, Morry J., Hoyne, Peter A., Jorissen, Robert N., Nice, Edouard C., Burgess, Antony W., Ward, Colin W.

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The Crystal Structure of a Truncated ErbB2 Ectodomain Reveals an Active Conformation, Poised to Interact with Other ErbB Receptors von Garrett, Thomas P.J., McKern, Neil M., Lou, Meizhen, Elleman, Thomas C., Adams, Timothy E., Lovrecz, George O., Kofler, Michael, Jorissen, Robert N., Nice, Edouard C., Burgess, Antony W., Ward, Colin W.

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