A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing von Vizoso, Miguel, E. J. Pritchard, Colin, Bombardelli, Lorenzo, van den Broek, Bram, Krimpenfort, Paul, Beijersbergen, Roderick L., Jalink, Kees, van Rheenen, Jacco

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A C57BL/6J Fancg-KO Mouse Model Generated by CRISPR/Cas9 Partially Captures the Human Phenotype von Shah, Ronak, van den Berk, Paul C M, Pritchard, Colin E J, Song, Ji-Ying, Kreft, Maaike, Pilzecker, Bas, Jacobs, Heinz

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HideRNAs protect against CRISPR-Cas9 re-cutting after successful single base-pair gene editing von Harmsen, Tim J. W., Pritchard, Colin E. J., Riepsaame, Joey, van de Vrugt, Henri J., Huijbers, Ivo J., te Riele, Hein

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Towards an understanding of C9orf82 protein/CAAP1 function von Aslam, Muhammad Assad, Alemdehy, Mir Farshid, Pritchard, Colin E J, Song, Ji-Ying, Muhaimin, Fitriari Izzatunnisa, Wijdeven, Ruud H, Huijbers, Ivo J, Neefjes, Jacques, Jacobs, Heinz

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Inhibition of carnitine palmitoyl-transferase 1 is a potential target in a mouse model of Parkinson’s disease von Trabjerg, Michael Sloth, Andersen, Dennis Christian, Huntjens, Pam, Mørk, Kasper, Warming, Nikolaj, Kullab, Ulla Bismark, Skjønnemand, Marie-Louise Nibelius, Oklinski, Michal Krystian, Oklinski, Kirsten Egelund, Bolther, Luise, Kroese, Lona J., Pritchard, Colin E. J., Huijbers, Ivo J., Corthals, Angelique, Søndergaard, Mads Toft, Kjeldal, Henrik Bech, Pedersen, Cecilie Fjord Morre, Nieland, John Dirk Vestergaard

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Direct Generation of Conditional Alleles Using CRISPR/Cas9 in Mouse Zygotes von Pritchard, Colin E. J., Kroese, Lona J., Huijbers, Ivo J.

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TRPS1 acts as a context-dependent regulator of mammary epithelial cell growth/differentiation and breast cancer development von Cornelissen, Lisette M, Drenth, Anne Paulien, van der Burg, Eline, de Bruijn, Roebi, Pritchard, Colin E J, Huijbers, Ivo J, Zwart, Wilbert, Jonkers, Jos

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A mouse model that is immunologically tolerant to reporter and modifier proteins von Bresser, Kaspar, Dijkgraaf, Feline E., Pritchard, Colin E. J., Huijbers, Ivo J., Song, Ji-Ying, Rohr, Jan C., Scheeren, Ferenc A., Schumacher, Ton N.

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A Lamb1Dendra2 mouse model identifies basement-membrane-producing origins and dynamics in PyMT breast tumors von Morgner, Jessica, Bornes, Laura, Hahn, Kerstin, López-Iglesias, Carmen, Kroese, Lona, Pritchard, Colin E.J., Vennin, Claire, Peters, Peter J., Huijbers, Ivo, van Rheenen, Jacco

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Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL von Antoszewski, Mateusz, Fournier, Nadine, Ruiz Buendía, Gustavo A., Lourenco, Joao, Liu, Yuanlong, Sugrue, Tara, Dubey, Christelle, Nkosi, Marianne, Pritchard, Colin E.J., Huijbers, Ivo J., Segat, Gabriela C., Alonso-Moreno, Sandra, Serracanta, Elisabeth, Belver, Laura, Ferrando, Adolfo A., Ciriello, Giovanni, Weng, Andrew P., Koch, Ute, Radtke, Freddy

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Mps1 inhibitors synergise with low doses of taxanes in promoting tumour cell death by enhancement of errors in cell division von Maia, Ana Rita R., Linder, Simon, Song, Ji-Ying, Vaarting, Chantal, Boon, Ute, Pritchard, Colin E. J., Velds, Arno, Huijbers, Ivo J., van Tellingen, Olaf, Jonkers, Jos, Medema, René H.

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Mammalian life depends on two distinct pathways of DNA damage tolerance von Buoninfante, Olimpia Alessandra, Pilzecker, Bas, Spanjaard, Aldo, de Groot, Daniël, Prekovic, Stefan, Song, Ji-Ying, Lieftink, Cor, Ayidah, Matilda, Pritchard, Colin E J, Vivié, Judith, Mcgrath, Kathleen E, Huijbers, Ivo J, Philipsen, Sjaak, von Lindern, Marieke, Zwart, Wilbert, Beijersbergen, Roderick L, Palis, James, van den Berk, Paul C M, Jacobs, Heinz

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A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair von Pulver, Emilia M, Mukherjee, Chirantani, van de Kamp, Gerarda, Roobol, Stefan J, Rother, Magdalena B, van der Gulden, Hanneke, de Bruijn, Roebi, Lattanzio, Maria Valeria, van der Burg, Eline, Drenth, Anne Paulien, Verkaik, Nicole S, Hahn, Kerstin, Klarenbeek, Sjoerd, de Korte-Grimmerink, Renske, van de Ven, Marieke, Pritchard, Colin E J, Huijbers, Ivo J, Xia, Bing, van Gent, Dik C, Essers, Jeroen, van Attikum, Haico, Ray Chaudhuri, Arnab, Bouwman, Peter, Jonkers, Jos

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The Ig heavy chain protein but not its message controls early B cell development von Aslam, Muhammad Assad, Alemdehy, Mir Farshid, Hao, Bingtao, Krijger, Peter H. L., Pritchard, Colin E. J., de Rink, Iris, Muhaimin, Fitriari Izzatunnisa, Nurzijah, Ika, van Baalen, Martijn, Kerkhoven, Ron M., van den Berk, Paul C. M., Skok, Jane A., Jacobs, Heinz

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Dual role of proliferating cell nuclear antigen monoubiquitination in facilitating Fanconi anemia-mediated interstrand crosslink repair von Shah, Ronak, Aslam, Muhammad Assad, Spanjaard, Aldo, de Groot, Daniel, Zürcher, Lisa M, Altelaar, Maarten, Hoekman, Liesbeth, Pritchard, Colin E J, Pilzecker, Bas, van den Berk, Paul C M, Jacobs, Heinz

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Loss of the volume-regulated anion channel components LRRC8A and LRRC8D limits platinum drug efficacy von Widmer, Carmen A, Klebic, Ismar, Domanitskaya, Natalya, Decollogny, Morgane, Howald, Denise, Siffert, Myriam, Essers, Paul, Nowicka, Zuzanna, Stokar-Regenscheit, Nadine, van de Ven, Marieke, de Korte-Grimmerink, Renske, Galván, José A, Pritchard, Colin E J, Huijbers, Ivo J, Fendler, Wojciech, Vens, Conchita, Rottenberg, Sven

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RAE1 Is a Shuttling mRNA Export Factor That Binds to a GLEBS-like NUP98 Motif at the Nuclear Pore Complex through Multiple Domains von Colin E. J. Pritchard, Fornerod, Maarten, Kasper, Lawryn H., Jan M. A. van Deursen

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CREB Binding Protein Interacts with Nucleoporin-Specific FG Repeats That Activate Transcription and Mediate NUP98-HOXA9 Oncogenicity von Kasper, Lawryn H., Brindle, Paul K., Schnabel, Catherine A., Pritchard, Colin E. J., Cleary, Michael L., van Deursen, Jan M. A.

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Mammalian life depends on two distinct pathways of DNA damage tolerance von Buoninfante, Olimpia Alessandra, Pilzecker, Bas, Spanjaard, Aldo, de Groot, Daniël, Prekovic, Stefan, Song, Ji-Ying, Lieftink, Cor, Ayidah, Matilda, Pritchard, Colin E J, Vivié, Judith, Mcgrath, Kathleen E, Huijbers, Ivo J, Philipsen, Sjaak, von Lindern, Marieke, Zwart, Wilbert, Beijersbergen, Roderick L, Palis, James, van den Berk, Paul C M, Jacobs, Heinz

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The Ig heavy chain protein but not its message controls early B cell development von Aslam, Muhammad Assad, Alemdehy, Mir Farshid, Hao, Bingtao, Krijger, Peter H L, Pritchard, Colin E J, de Rink, Iris, Muhaimin, Fitriari Izzatunnisa, Nurzijah, Ika, van Baalen, Martijn, Kerkhoven, Ron M, van den Berk, Paul C M, Skok, Jane A, Jacobs, Heinz

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