The sirtuin SIRT6 regulates lifespan in male mice von Kanfi, Yariv, Naiman, Shoshana, Amir, Gail, Peshti, Victoria, Zinman, Guy, Nahum, Liat, Bar-Joseph, Ziv, Cohen, Haim Y.

Volltext

LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation von Simon, Matthew, Van Meter, Michael, Ablaeva, Julia, Ke, Zhonghe, Gonzalez, Raul S., Taguchi, Taketo, De Cecco, Marco, Leonova, Katerina I., Kogan, Valeria, Helfand, Stephen L., Neretti, Nicola, Roichman, Asael, Cohen, Haim Y., Meer, Margarita V., Gladyshev, Vadim N., Antoch, Marina P., Gudkov, Andrei V., Sedivy, John M., Seluanov, Andrei, Gorbunova, Vera

Volltext

Telomeres and Longevity: A Cause or an Effect? von Adwan Shekhidem, Huda, Sharvit, Lital, Leman, Eva, Manov, Irena, Roichman, Asael, Holtze, Susanne, M Huffman, Derek, Y Cohen, Haim, Bernd Hildebrandt, Thomas, Shams, Imad, Atzmon, Gil

Volltext

The complex role of SIRT6 in carcinogenesis von Lerrer, Batia, Gertler, Asaf A, Cohen, Haim Y

Volltext

Multiple Regulatory Layers of SREBP1/2 by SIRT6 von Elhanati, Sivan, Kanfi, Yariv, Varvak, Alexander, Roichman, Asael, Carmel-Gross, Ilana, Barth, Shaul, Gibor, Gilad, Cohen, Haim Y.

Volltext

Mammalian conserved ADAR targets comprise only a small fragment of the human editosome von Pinto, Yishay, Cohen, Haim Y, Levanon, Erez Y

Volltext

Reciprocal Regulation between SIRT6 and miR-122 Controls Liver Metabolism and Predicts Hepatocarcinoma Prognosis von Elhanati, Sivan, Ben-Hamo, Rotem, Kanfi, Yariv, Varvak, Alexander, Glazz, Renana, Lerrer, Batia, Efroni, Sol, Cohen, Haim Y.

Volltext

Role for the longevity protein SIRT6 in primate development von Naiman, Shoshana, Cohen, Haim Y.

Volltext

Sirtuin 6 protects the heart from hypoxic damage von Maksin-Matveev, Anna, Kanfi, Yariv, Hochhauser, Edith, Isak, Ahuva, Cohen, Haim Y., Shainberg, Asher

Volltext

Characterization of physiological defects in adult SIRT6-/- mice von Peshti, Victoria, Obolensky, Alexey, Nahum, Liat, Kanfi, Yariv, Rathaus, Moran, Avraham, Maytal, Tinman, Simon, Alt, Fredrick W, Banin, Eyal, Cohen, Haim Y

Volltext

SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα von Naiman, Shoshana, Huynh, Frank K., Gil, Reuven, Glick, Yair, Shahar, Yael, Touitou, Noga, Nahum, Liat, Avivi, Matan Y., Roichman, Asael, Kanfi, Yariv, Gertler, Asaf A., Doniger, Tirza, Ilkayeva, Olga R., Abramovich, Ifat, Yaron, Orly, Lerrer, Batia, Gottlieb, Eyal, Harris, Robert A., Gerber, Doron, Hirschey, Matthew D., Cohen, Haim Y.

Volltext

Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide von Schmeisser, Kathrin, Mansfeld, Johannes, Kuhlow, Doreen, Weimer, Sandra, Priebe, Steffen, Heiland, Ines, Birringer, Marc, Groth, Marco, Segref, Alexandra, Kanfi, Yariv, Price, Nathan L, Schmeisser, Sebastian, Schuster, Stefan, Pfeiffer, Andreas F H, Guthke, Reinhard, Platzer, Matthias, Hoppe, Thorsten, Cohen, Haim Y, Zarse, Kim, Sinclair, David A, Ristow, Michael

Volltext

SIRT6 exhibits nucleosome-dependent deacetylase activity von Gil, Reuven, Barth, Shaul, Kanfi, Yariv, Cohen, Haim Y

Volltext

Copy number variation as a tool for implementing pregnancy as an aging model von Andrawus, Mariana, Sharvit, Lital, Touitou, Noga, Lerrer, Batia, Cohen, Haim Y., Atzmon, Gil

Volltext

SIRT6 protects against pathological damage caused by diet‐induced obesity von Kanfi, Yariv, Peshti, Victoria, Gil, Reuven, Naiman, Shoshana, Nahum, Liat, Levin, Eran, Kronfeld‐Schor, Noga, Cohen, Haim Y.

Volltext

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase von Cohen, H.Y, Miller, C, Bitterman, K.J, Wall, N.R, Hekking, B, Kessler, B, Howitz, K.T, Gorospe, M, de Cabo, R, Sinclair, D.A

Volltext

The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance von Chuprin, Anna, Avin, Ayelet, Goldfarb, Yael, Herzig, Yonatan, Levi, Ben, Jacob, Adi, Sela, Asaf, Katz, Shir, Grossman, Moran, Guyon, Clotilde, Rathaus, Moran, Cohen, Haim Y, Sagi, Irit, Giraud, Matthieu, McBurney, Michael W, Husebye, Eystein S, Abramson, Jakub

Volltext

On-line in situ determination of deuterium content in water via FTIR spectroscopy von Litvak, Ira, Anker, Yaakov, Cohen, Haim

Volltext

SIRT6 Overexpression Improves Various Aspects of Mouse Healthspan von Roichman, Asael, Kanfi, Yariv, Glazz, Renana, Naiman, Shoshana, Amit, Uri, Landa, Natalie, Tinman, Simon, Stein, Ilan, Pikarsky, Eli, Leor, Jonathan, Cohen, Haim Y

Volltext

Dynamic regulation of N6,2′-O-dimethyladenosine (m6Am) in obesity von Ben-Haim, Moshe Shay, Pinto, Yishay, Moshitch-Moshkovitz, Sharon, Hershkovitz, Vera, Kol, Nitzan, Diamant-Levi, Tammy, Beeri, Michal Schnaider, Amariglio, Ninette, Cohen, Haim Y., Rechavi, Gideon

Volltext