SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage von Clifford, Ruth, Louis, Tania, Robbe, Pauline, Ackroyd, Sam, Burns, Adam, Timbs, Adele T., Wright Colopy, Glen, Dreau, Helene, Sigaux, Francois, Judde, Jean Gabriel, Rotger, Margalida, Telenti, Amalio, Lin, Yea-Lih, Pasero, Philippe, Maelfait, Jonathan, Titsias, Michalis, Cohen, Dena R., Henderson, Shirley J., Ross, Mark T., Bentley, David, Hillmen, Peter, Pettitt, Andrew, Rehwinkel, Jan, Knight, Samantha J.L., Taylor, Jenny C., Crow, Yanick J., Benkirane, Monsef, Schuh, Anna

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Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: sustained efficacy and improved survival von Kelly, Richard J., Hill, Anita, Arnold, Louise M., Brooksbank, Gemma L., Richards, Stephen J., Cullen, Matthew, Mitchell, Lindsay D., Cohen, Dena R., Gregory, Walter M., Hillmen, Peter

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Adding a treatment arm to an ongoing clinical trial: a review of methodology and practice von Cohen, Dena R, Todd, Susan, Gregory, Walter M, Brown, Julia M

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A randomized phase II trial of fludarabine, cyclophosphamide and mitoxantrone (FCM) with or without rituximab in previously treated chronic lymphocytic leukaemia von Hillmen, Peter, Cohen, Dena R., Cocks, Kim, Pettitt, Andrew, Sayala, Hazem A., Rawstron, Andy C., Kennedy, Daniel B., Fegan, Christopher, Milligan, Don W., Radford, John, Mercieca, Jane, Dearden, Claire, Ezekwisili, Raphael, Smith, Alexandra F., Brown, Julia, Booth, Gillian A., Varghese, Abraham M., Pocock, Christopher

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Measurement of saliva tacrolimus levels in pediatric renal transplant recipients von Belostotsky, Vladimir, Adaway, Jo, Keevil, Brian G., Cohen, Dena R., Webb, Nicholas J. A.

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Experiences in the design and implementation of phase II trials in CLL von Cohen, Dena R, Hillmen, Peter, Brown, Julia M, Gregory, Walter M

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Long Term Treatment with Eculizumab In Paroxysmal Nocturnal Hemoglobinuria (PNH): Sustained Efficacy and Improved Survival von Kelly, Richard J, Hill, Anita, Mitchell, Lindsay D, Richards, Stephen John, Arnold, Louise M, Valters, Gemma L, Cullen, Matthew, Cohen, Dena R, Gregory, Walter M, Hillmen, Peter

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Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway von Jeong, Hyunkyung, Cohen, Dena E, Cui, Libin, Supinski, Andrea, Savas, Jeffrey N, Mazzulli, Joseph R, Yates, John R, Bordone, Laura, Guarente, Leonard, Krainc, Dimitri

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Community-Based HIV Testing for Urban Youth in Western Kenya von Truong, Hong-Ha M., Guzé, Mary A., Ouma, David, Bushman, Dena, Mocello, A. Rain, Kadede, Kevin, Bukusi, Elizabeth A., Odhiambo, Francesca, Cohen, Craig R.

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Analysis of VHL Gene Alterations and their Relationship to Clinical Parameters in Sporadic Conventional Renal Cell Carcinoma von YOUNG, Alison C, CRAVEN, Rachel A, KNOWLES, Margaret A, JOYCE, Adrian, SELBY, Peter J, BANKS, Rosamonde E, COHEN, Dena, TAYLOR, Claire, BOOTH, Christopher, HARNDEN, Patricia, CAIRNS, David A, ASTUTI, Dewi, GREGORY, Walter, MAHER, Eamonn R

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Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features von Robbe, Pauline, Ridout, Kate E., Vavoulis, Dimitrios V., Dréau, Helene, Kinnersley, Ben, Denny, Nicholas, Chubb, Daniel, Appleby, Niamh, Cutts, Anthony, Cornish, Alex J., Lopez-Pascua, Laura, Clifford, Ruth, Burns, Adam, Stamatopoulos, Basile, Cabes, Maite, Alsolami, Reem, Antoniou, Pavlos, Oates, Melanie, Cavalieri, Doriane, Gibson, Jane, Prabhu, Anika V., Schwessinger, Ron, Jennings, Daisy, James, Terena, Maheswari, Uma, Duran-Ferrer, Martí, Carninci, Piero, Knight, Samantha J. L., Månsson, Robert, Hughes, Jim, Davies, James, Ross, Mark, Bentley, David, Strefford, Jonathan C., Devereux, Stephen, Pettitt, Andrew R., Hillmen, Peter, Caulfield, Mark J., Houlston, Richard S., Martín-Subero, José I., Schuh, Anna

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Congenital polyvalvular disease expands the cardiac phenotype of the RASopathies von Matalon, Dena R., Stevenson, David A., Bhoj, Elizabeth J., Santani, Avni B., Keena, Beth, Cohen, Meryl S., Lin, Angela E., Sheppard, Sarah E., Zackai, Elaine H.

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Rituximab Plus Chlorambucil As First-Line Treatment for Chronic Lymphocytic Leukemia: Final Analysis of an Open-Label Phase II Study von HILLMEN, Peter, GRIBBEN, John G, NATHWANI, Amit, VARGHESE, Abraham, COHEN, Dena, RAWSTRON, Andy, OERTEL, Stephan, POCOCK, Christopher F. E, FOLLOWS, George A, MILLIGAN, Donald, SAYALA, Hazem A, MORETON, Paul, OSCIER, David G, DEARDEN, Claire E, KENNEDY, Daniel B, PETTITT, Andrew R

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Implementation of a Community-Based Hybrid HIV Testing Services Program as a Strategy to Saturate Testing Coverage in Western Kenya von Truong, Hong-Ha M, Akama, Eliud, Guzé, Mary A, Otieno, Frankline, Obunge, Duncan, Wandera, Esther, Nsengiyumva, Ntwali Placide, Obabo, Sammy, Bushman, Dena, Kadede, Kevin, Bukusi, Elizabeth A, Oyaro, Patrick, Cohen, Craig R

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Genetic and epigenetic analysis of von hippel-lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer von BANKS, Rosamonde E, TIRUKONDA, Prasanna, KNOWLES, Margaret, SELBY, Peter J, TAYLOR, Claire, HORNIGOLD, Nick, ASTUTI, Dewi, COHEN, Dena, MAHER, Eamonn R, STANLEY, Anthea J, HARNDEN, Patricia, JOYCE, Adrian

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A Multi-Center Dose-Finding Study to Assess Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Fimepinostat (CUDC-907) in Combination with Venetoclax in Patients wi... von Younes, Anas, Batlevi, Connie Lee, Cohen, Jonathon B., de Vos, Sven, Landsburg, Daniel J., Myint, Zaw Win, Patel, Krish, Phillips, Tycel J., Smith, Sonali M., Westin, Jason R., Ma, Anna W, Grayson, Dena, von Roemeling, Reinhard, Barta, Stefan K.

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Obinutuzumab As Consolidation after Chemo-Immunotherapy Is Highly Effective in Achieving MRD Clearance from Bone Marrow and Peripheral Blood- Initial Results of UK NCRI Phase II/II... von Munir, Talha, Hillmen, Peter, McParland, Lucy, Cohen, Dena, Hockaday, Anna, Oughton, Jamie, Messina, Fabrizio, Phillips, David, Neilson, Jeffrey R., Pemberton, Nicholas, Paneesha, Shankara, Kennedy, Ben, Rawstron, Andy

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Prognostic factors identified three risk groups in the LRF CLL4 trial, independent of treatment allocation von OSCIER, David, WADE, Rachel, DAVIS, Zadie, MORILLA, Alison, BEST, Giles, RICHARDS, Sue, ELSE, Monica, MATUTES, Estella, CATOVSKY, Daniel

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Community-based HIV testing services in an urban setting in western Kenya: a programme implementation study von Truong, Hong-Ha M, Mocello, A Rain, Ouma, David, Bushman, Dena, Kadede, Kevin, Ating'a, Eric, Obunge, Duncan, Bukusi, Elizabeth A, Odhiambo, Francesca, Cohen, Craig R

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Community-Based HIV Testing Services in an Urban Setting in Western Kenya: a program implementation von Truong, Hong-Ha M., Rain Mocello, A., Ouma, David, Bushman, Dena, Kadede, Kevin, Ating’a, Eric, Obunge, Duncan, Bukusi, Elizabeth A., Odhiambo, Francesca, Cohen, Craig R.

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