OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response von Jacquemin, Clément, Schmitt, Nathalie, Contin-Bordes, Cécile, Liu, Yang, Narayanan, Priya, Seneschal, Julien, Maurouard, Typhanie, Dougall, David, Davizon, Emily Spence, Dumortier, Hélène, Douchet, Isabelle, Raffray, Loïc, Richez, Christophe, Lazaro, Estibaliz, Duffau, Pierre, Truchetet, Marie-Elise, Khoryati, Liliane, Mercié, Patrick, Couzi, Lionel, Merville, Pierre, Schaeverbeke, Thierry, Viallard, Jean-François, Pellegrin, Jean-Luc, Moreau, Jean-François, Muller, Sylviane, Zurawski, Sandy, Coffman, Robert L., Pascual, Virginia, Ueno, Hideki, Blanco, Patrick

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Selective Utilization of Toll-like Receptor and MyD88 Signaling in B Cells for Enhancement of the Antiviral Germinal Center Response von Hou, Baidong, Saudan, Philippe, Ott, Gary, Wheeler, Matthew L., Ji, Ming, Kuzmich, Lili, Lee, Linda M., Coffman, Robert L., Bachmann, Martin F., DeFranco, Anthony L.

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Development of CpG-adjuvanted stable prefusion SARS-CoV-2 spike antigen as a subunit vaccine against COVID-19 von Kuo, Tsun-Yung, Lin, Meei-Yun, Coffman, Robert L., Campbell, John D., Traquina, Paula, Lin, Yi-Jiun, Liu, Luke Tzu-Chi, Cheng, Jinyi, Wu, Yu-Chi, Wu, Chung-Chin, Tang, Wei-Hsuan, Huang, Chung-Guei, Tsao, Kuo-Chien, Chen, Charles

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Development of TLR inhibitors for the treatment of autoimmune diseases von Barrat, Franck J, Coffman, Robert L

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RNA recognition by human TLR8 can lead to autoimmune inflammation von Guiducci, Cristiana, Gong, Mei, Cepika, Alma-Martina, Xu, Zhaohui, Tripodo, Claudio, Bennett, Lynda, Crain, Chad, Quartier, Pierre, Cush, John J, Pascual, Virginia, Coffman, Robert L, Barrat, Franck J

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TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus von Barrat, Franck J, Soumelis, Vassili, Chaussabel, Damien, Punaro, Marilynn, Guiducci, Cristiana, Wright, Tracey, Coffman, Robert L, Gill, Michelle, Meeker, Thea, Bolland, Silvia, Banchereau, Jacques, Xu, Zhaohui, Gong, Mei, Pascual, Virginia, Chan, Jean H

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Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus von Barrat, Franck J, Meeker, Thea, Gregorio, Josh, Chan, Jean H, Uematsu, Satoshi, Akira, Shizuo, Chang, Bonnie, Duramad, Omar, Coffman, Robert L

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Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9 von Guiducci, Cristiana, Tripodo, Claudio, Gong, Mei, Sangaletti, Sabina, Colombo, Mario P, Coffman, Robert L, Barrat, Franck J

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A Phase 2a, Double-Blind, Placebo-controlled Randomized Trial of Inhaled TLR9 Agonist AZD1419 in Asthma von Psallidas, Ioannis, Backer, Vibeke, Kuna, Piotr, Palmer, Robert, Necander, Sofia, Aurell, Malin, Korsback, Katarina, Taib, Ziad, Hashemi, Mahdi, Gustafson, Per, Asimus, Sara, Delaney, Stephen, Pardali, Katerina, Jiang, Fanyi, Almquist, Joachim, Jackson, Sam, Coffman, Robert L., Keeling, David, Sethi, Tariq

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INTERLEUKIN-10 AND THE INTERLEUKIN-10 RECEPTOR von Moore, Kevin W, de Waal Malefyt, Rene, Coffman, Robert L, O'Garra, Anne

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Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation von Guiducci, Cristiana, Ott, Gary, Chan, Jean H, Damon, Emily, Calacsan, Carlo, Matray, Tracy, Lee, Kyung-Dall, Coffman, Robert L, Barrat, Franck J

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PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation von Guiducci, Cristiana, Ghirelli, Cristina, Marloie-Provost, Marie-Annick, Matray, Tracy, Coffman, Robert L, Liu, Yong-Jun, Barrat, Franck J, Soumelis, Vassili

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Intratumoral injection of a CpG oligonucleotide reverts resistance to PD-1 blockade by expanding multifunctional CD8⁺ T cells von Wang, Shu, Campos, Jose, Gallotta, Marilena, Gong, Mei, Crain, Chad, Naik, Edwina, Coffman, Robert L., Guiducci, Cristiana

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Vaccine Adjuvants: Putting Innate Immunity to Work von Coffman, Robert L., Sher, Alan, Seder, Robert A.

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The Origin of TH2 Responses von Coffman, Robert L

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Preclinical development of the TLR9 agonist DV281 as an inhaled aerosolized immunotherapeutic for lung cancer: Pharmacological profile in mice, non-human primates, and human primar... von Kell, Sariah A., Kachura, Melissa A., Renn, Alex, Traquina, Paula, Coffman, Robert L., Campbell, John D.

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A CpG-Ficoll Nanoparticle Adjuvant for Anthrax Protective Antigen Enhances Immunogenicity and Provides Single-Immunization Protection against Inhaled Anthrax in Monkeys von Kachura, Melissa A, Hickle, Colin, Kell, Sariah A, Sathe, Atul, Calacsan, Carlo, Kiwan, Radwan, Hall, Brian, Milley, Robert, Ott, Gary, Coffman, Robert L, Kanzler, Holger, Campbell, John D

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A CpG 1018 adjuvanted neuraminidase vaccine provides robust protection from influenza virus challenge in mice von Strohmeier, Shirin, Amanat, Fatima, Campbell, John D., Traquina, Paula, Coffman, Robert L., Krammer, Florian

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Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice von Grigoryan, Lilit, Lee, Audrey, Walls, Alexandra C., Lai, Lilin, Franco, Benjamin, Arunachalam, Prabhu S., Feng, Yupeng, Luo, Wei, Vanderheiden, Abigail, Floyd, Katharine, Wrenn, Samuel, Pettie, Deleah, Miranda, Marcos C., Kepl, Elizabeth, Ravichandran, Rashmi, Sydeman, Claire, Brunette, Natalie, Murphy, Michael, Fiala, Brooke, Carter, Lauren, Coffman, Robert L., Novack, David, Kleanthous, Harry, O’Hagan, Derek T., van der Most, Robbert, McLellan, Jason S., Suthar, Mehul, Veesler, David, King, Neil P., Pulendran, Bali

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New IL-17 Family Members Promote Th1 or Th2 Responses in the Lung: In Vivo Function of the Novel Cytokine IL-25 von Hurst, Stephen D, Muchamuel, Tony, Gorman, Daniel M, Gilbert, Jonathan M, Clifford, Theresa, Kwan, Sylvia, Menon, Satish, Seymour, Brian, Jackson, Craig, Kung, Ted T, Brieland, Joan K, Zurawski, Sandra M, Chapman, Richard W, Zurawski, Gerard, Coffman, Robert L

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