A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications von Flynn, E. Megan, Huang, Oscar W., Poy, Florence, Oppikofer, Mariano, Bellon, Steve F., Tang, Yong, Cochran, Andrea G.

Volltext

BMI1–RING1B is an autoinhibited RING E3 ubiquitin ligase von Taherbhoy, Asad M., Huang, Oscar W., Cochran, Andrea G.

Volltext

An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells von Vinogradova, Maia, Gehling, Victor S, Gustafson, Amy, Arora, Shilpi, Tindell, Charles A, Wilson, Catherine, Williamson, Kaylyn E, Guler, Gulfem D, Gangurde, Pranoti, Manieri, Wanda, Busby, Jennifer, Flynn, E Megan, Lan, Fei, Kim, Hyo-jin, Odate, Shobu, Cochran, Andrea G, Liu, Yichin, Wongchenko, Matthew, Yang, Yibin, Cheung, Tommy K, Maile, Tobias M, Lau, Ted, Costa, Michael, Hegde, Ganapati V, Jackson, Erica, Pitti, Robert, Arnott, David, Bailey, Christopher, Bellon, Steve, Cummings, Richard T, Albrecht, Brian K, Harmange, Jean-Christophe, Kiefer, James R, Trojer, Patrick, Classon, Marie

Volltext

Wnt Antagonists Bind through a Short Peptide to the First β-Propeller Domain of LRP5/6 von Bourhis, Eric, Wang, Weiru, Tam, Christine, Hwang, Jiyoung, Zhang, Yingnan, Spittler, Didier, Huang, Oscar W., Gong, Yan, Estevez, Alberto, Zilberleyb, Inna, Rouge, Lionel, Chiu, Cecilia, Wu, Yan, Costa, Mike, Hannoush, Rami N., Franke, Yvonne, Cochran, Andrea G.

Volltext

Reconstitution of a Frizzled8·Wnt3a·LRP6 Signaling Complex Reveals Multiple Wnt and Dkk1 Binding Sites on LRP6 von Bourhis, Eric, Tam, Christine, Franke, Yvonne, Bazan, J. Fernando, Ernst, James, Hwang, Jiyoung, Costa, Mike, Cochran, Andrea G., Hannoush, Rami N.

Volltext

Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex von Bentley, Matthew L, Corn, Jacob E, Dong, Ken C, Phung, Qui, Cheung, Tommy K, Cochran, Andrea G

Volltext

Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300 von Crawford, Terry D, Romero, F. Anthony, Lai, Kwong Wah, Tsui, Vickie, Taylor, Alexander M, de Leon Boenig, Gladys, Noland, Cameron L, Murray, Jeremy, Ly, Justin, Choo, Edna F, Hunsaker, Thomas L, Chan, Emily W, Merchant, Mark, Kharbanda, Samir, Gascoigne, Karen E, Kaufman, Susan, Beresini, Maureen H, Liao, Jiangpeng, Liu, Wenfeng, Chen, Kevin X, Chen, Zhongguo, Conery, Andrew R, Côté, Alexandre, Jayaram, Hariharan, Jiang, Ying, Kiefer, James R, Kleinheinz, Tracy, Li, Yingjie, Maher, Jonathan, Pardo, Eneida, Poy, Florence, Spillane, Kerry L, Wang, Fei, Wang, Jian, Wei, Xiaocang, Xu, Zhaowu, Xu, Zhongya, Yen, Ivana, Zawadzke, Laura, Zhu, Xiaoyu, Bellon, Steven, Cummings, Richard, Cochran, Andrea G, Albrecht, Brian K, Magnuson, Steven

Volltext

Bromodomains: a new target class for drug development von Cochran, Andrea G., Conery, Andrew R., Sims, Robert J.

Volltext

GNE-235: A Lead Compound Selective for the Second Bromodomain of PBRM1 von Cochran, Andrea G., Flynn, Megan

Volltext

Non-canonical reader modules of BAZ1A promote recovery from DNA damage von Oppikofer, Mariano, Sagolla, Meredith, Haley, Benjamin, Zhang, Hui-Min, Kummerfeld, Sarah K., Sudhamsu, Jawahar, Flynn, E. Megan, Bai, Tianyi, Zhang, Jennifer, Ciferri, Claudio, Cochran, Andrea G.

Volltext

Tryptophan Zippers: Stable, Monomeric β-Hairpins von Cochran, Andrea G., Skelton, Nicholas J., Starovasnik, Melissa A.

Volltext

Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance von Crawford, Terry D., Vartanian, Steffan, Côté, Alexandre, Bellon, Steve, Duplessis, Martin, Flynn, E. Megan, Hewitt, Michael, Huang, Hon-Ren, Kiefer, James R., Murray, Jeremy, Nasveschuk, Christopher G., Pardo, Eneida, Romero, F. Anthony, Sandy, Peter, Tang, Yong, Taylor, Alexander M., Tsui, Vickie, Wang, Jian, Wang, Shumei, Zawadzke, Laura, Albrecht, Brian K., Magnuson, Steven R., Cochran, Andrea G., Stokoe, David

Volltext

Expansion of the ISWI chromatin remodeler family with new active complexes von Oppikofer, Mariano, Bai, Tianyi, Gan, Yutian, Haley, Benjamin, Liu, Peter, Sandoval, Wendy, Ciferri, Claudio, Cochran, Andrea G

Volltext

The Mitotic Regulator Survivin Binds as a Monomer to Its Functional Interactor Borealin von Bourhis, Eric, Hymowitz, Sarah G., Cochran, Andrea G.

Volltext

Short Constrained Peptides That Inhibit HIV-1 Entry von Sia, Samuel K., Carr, Peter A., Cochran, Andrea G., Malashkevich, Vladimir N., Kim, Peter S.

Volltext

Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6 von Bourhis, Eric, Tam, Christine, Franke, Yvonne, Bazan, J Fernando, Ernst, James, Hwang, Jiyoung, Costa, Mike, Cochran, Andrea G, Hannoush, Rami N

Volltext

Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells von Rutz, Sascha, Kayagaki, Nobuhiko, Phung, Qui T., Eidenschenk, Celine, Noubade, Rajkumar, Wang, Xiaoting, Lesch, Justin, Lu, Rongze, Newton, Kim, Huang, Oscar W., Cochran, Andrea G., Vasser, Mark, Fauber, Benjamin P., DeVoss, Jason, Webster, Joshua, Diehl, Lauri, Modrusan, Zora, Kirkpatrick, Donald S., Lill, Jennie R., Ouyang, Wenjun, Dixit, Vishva M.

Volltext

Trifluoroacetyl Lysine as a Bromodomain Binding Mimic of Lysine Acetylation von Miller, Gregory M., Flynn, E. Megan, Tom, Jeffrey, Song, Aimin, Cochran, Andrea G.

Volltext

Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains von Crawford, Terry D, Tsui, Vickie, Flynn, E. Megan, Wang, Shumei, Taylor, Alexander M, Côté, Alexandre, Audia, James E, Beresini, Maureen H, Burdick, Daniel J, Cummings, Richard, Dakin, Les A, Duplessis, Martin, Good, Andrew C, Hewitt, Michael C, Huang, Hon-Ren, Jayaram, Hariharan, Kiefer, James R, Jiang, Ying, Murray, Jeremy, Nasveschuk, Christopher G, Pardo, Eneida, Poy, Florence, Romero, F. Anthony, Tang, Yong, Wang, Jian, Xu, Zhaowu, Zawadzke, Laura E, Zhu, Xiaoyu, Albrecht, Brian K, Magnuson, Steven R, Bellon, Steve, Cochran, Andrea G

Volltext

GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1 von Taylor, Alexander M., Bailey, Chris, Belmont, Lisa D., Campbell, Robert, Cantone, Nico, Côté, Alexandre, Crawford, Terry D., Cummings, Richard, DeMent, Kevin, Duplessis, Martin, Flynn, Megan, Good, Andrew C., Huang, Hon-Ren, Joshi, Shivangi, Leblanc, Yves, Murray, Jeremy, Nasveschuk, Christopher G., Neiss, Adrianne, Poy, Florence, Romero, F. Anthony, Sandy, Peter, Tang, Yong, Tsui, Vickie, Zawadzke, Laura, Sims, Robert J., Audia, James E., Bellon, Steven F., Magnuson, Steven R., Albrecht, Brian K., Cochran, Andrea G.

Volltext