Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-( N, N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious fa... von Zhang, Penglie, Huang, Wenrong, Wang, Lingyan, Bao, Liang, Jia, Zhaozhong J., Bauer, Shawn M., Goldman, Erick A., Probst, Gary D., Song, Yonghong, Su, Ting, Fan, Jingmei, Wu, Yanhong, Li, Wenhao, Woolfrey, John, Sinha, Uma, Wong, Paul W., Edwards, Susan T., Arfsten, Ann E., Clizbe, Lane A., Kanter, James, Pandey, Anjali, Park, Gary, Hutchaleelaha, Athiwat, Lambing, Joseph L., Hollenbach, Stanley J., Scarborough, Robert M., Zhu, Bing-Yan

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1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as potent factor xa inhibitors. Part 2: A survey of P4 motifs von JIA, Zhaozhong J, YANHONG WU, HUTCHALEELAHA, Athiwat, SCARBOROUGH, Robert M, ZHU, Bing-Yan, WENRONG HUANG, PENGLIE ZHANG, CLIZBE, Lane A, GOLDMAN, Erick A, SINHA, Uma, ARFSTEN, Ann E, EDWARDS, Susan T, ALPHONSO, Merlyn

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Design, synthesis and structure–Activity relationships of benzoxazinone-Based factor Xa inhibitors von Huang, Wenrong, Zhang, Penglie, Zuckett, Jingmei F, Wang, Lingyan, Woolfrey, John, Song, Yonghong, Jia, Zhaozhong J, Clizbe, Lane A, Su, Ting, Tran, Katherine, Huang, Brian, Wong, Paul, Sinha, Uma, Park, Gary, Reed, Andrea, Malinowski, John, Hollenbach, Stanley J, Scarborough, Robert M, Zhu, Bing-Yan

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Novel tricyclic benzothiazolo[2,3-c]thiadiazine antagonists of the platelet ADP receptor (P2Y12) von SCARBOROUGH, Robert M, LAIBELMAN, Alan M, CLIZBE, Lane A, FRETTO, Larry J, CONLEY, Pamela B, REYNOLDS, Elwood E, SEDLOCK, David M, JANTZEN, Hans-Michael

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N, N-Dialkylated 4-(4-arylsulfonylpiperazine-1-carbonyl)-benzamidines and 4-((4-arylsulfonyl)-2-oxo-piperazin-1-ylmethyl)-benzamidines as potent factor Xa inhibitors von JIA, Zhaozhong J, TING SU, WENRONG HUANG, WOOLFREY, John, SINHA, Uma, ARFSTEN, Ann E, HUTCHALEELAHA, Athiwat, HOLLENBACH, Stanley J, LAMBING, Joseph L, SCARBOROUGH, Robert M, ZHU, Bing-Yan, ZUCKETT, Jingmei F, YANHONG WU, GOLDMAN, Erick A, WENHAO LI, PENGLIE ZHANG, CLIZBE, Lane A, YONGHONG SONG, BAUER, Shawn M

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Design and synthesis of factor Xa inhibitors and their prodrugs von Song, Yonghong, Clizbe, Lane, Bhakta, Chhaya, Teng, Willy, Wong, Paul, Huang, Brian, Tran, Katherine, Sinha, Uma, Park, Gary, Reed, Andrea, Scarborough, Robert M, Zhu, Bing-Yan

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Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido )-5-metho xybenzamide, a highly potent, selective, and orally efficacious fa... von Zhang, Penglie, Huang, Wenrong, Wang, Lingyan, Bao, Liang, Jia, Zhaozhong J, Bauer, Shawn M, Goldman, Erick A, Probst, Gary D, Song, Yonghong, Su, Ting, Fan, Jingmei, Wu, Yanhong, Li, Wenhao, Woolfrey, John, Sinha, Uma, Wong, Paul W, Edwards, Susan T, Arfsten, Ann E, Clizbe, Lane A, Kanter, James, Pandey, Anjali, Park, Gary, Hutchaleelaha, Athiwat, Lambing, Joseph L, Hollenbach, Stanley J, Scarborough, Robert M, Zhu, Bing-Yan

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MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES von Clizbe, Lane A, Charles, Stephen A, Benoit, Didier G, To, Wayne, Perlroth, Daniel Victor

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Multifunctional zwitterionic polymer conjugates von Clizbe, Lane A, Charles, Stephen A, Benoit, Didier G, Perlroth, D. Victor, To, Wayne

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Thermal rearrangements of propargylic trichloroacetimidates. Synthesis of (trichloroacetamido)-1,3-dienes and -1,2-dienes von Overman, Larry E, Clizbe, Lane A, Freerks, Robert L, Marlowe, Charles K

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MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES von BENOIT, Didier G, CLIZBE, Lane A, CHARLES, Stephen A, PERLROTH, Victor D, TO, Wayne

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MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES von BENOIT, Didier G, CLIZBE, Lane A, CHARLES, Stephen A, PERLROTH, Victor D, TO, Wayne

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Substituted acrylamides as factor Xa inhibitors: improving bioavailability by P1 modification von Song, Yonghong, Clizbe, Lane, Bhakta, Chhaya, Teng, Willy, Li, Wenhao, Wong, Paul, Huang, Brian, Sinha, Uma, Park, Gary, Reed, Andrea, Scarborough, Robert M, Zhu, Bing-Yan

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MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES von CLIZBE, LANE A, BENOIT, DIDIER G, PERLROTH, VICTOR D, TO, WAYNE, CHARLES, STEPHEN A

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MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES von Clizbe, Lane A, Charles, Stephen A, Benoit, Didier G, Perlroth, D. Victor, To, Wayne

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A simple synthesis of L-.gamma.-carboxyglutamate and derivatives thereof von Danishefsky, Samuel, Berman, Ellen, Clizbe, Lane A, Hirama, Masahiro

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Diels-Alder reactions of 1-(acylamino)-1,3-dienes von Overman, Larry E, Freerks, Robert L, Petty, C. Bruce, Clizbe, Lane A, Ono, Robert K, Taylor, Garry F, Jessup, Peter J

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Inhibition of Purified Factor Xa Amidolytic Activity May Not Be Predictive of Inhibition of In Vivo Thrombosis: Implications for Identification of Therapeutically Active Inhibitors von Sinha, Uma, Lin, Pei Hua, Edwards, Susan T, Wong, Paul W, Zhu, Bingyan, Scarborough, Robert M, Su, Ting, Jia, Zhaozhong J, Song, Yonghong, Zhang, Penglie, Clizbe, Lane, Park, Gary, Reed, Andrea, Hollenbach, Stanley J, Malinowski, John, Arfsten, Ann E

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Total synthesis of pretyrosine (arogenate) von Danishefsky, Samuel, Morris, Joel, Clizbe, Lane A

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1-(2-Naphthyl)-1 H -pyrazole-5-carboxylamides as potent factor Xa inhibitors. Part 2: A survey of P4 motifs von Jia, Zhaozhong J., Wu, Yanhong, Huang, Wenrong, Zhang, Penglie, Clizbe, Lane A., Goldman, Erick A., Sinha, Uma, Arfsten, Ann E., Edwards, Susan T., Alphonso, Merlyn, Hutchaleelaha, Athiwat, Scarborough, Robert M., Zhu, Bing-Yan

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