Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications von Vatine, Gad D., Barrile, Riccardo, Workman, Michael J., Sances, Samuel, Barriga, Bianca K., Rahnama, Matthew, Barthakur, Sonalee, Kasendra, Magdalena, Lucchesi, Carolina, Kerns, Jordan, Wen, Norman, Spivia, Weston R., Chen, Zhaohui, Van Eyk, Jennifer, Svendsen, Clive N.

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Recent advances in human iPSC-derived models of the blood-brain barrier von Workman, Michael J, Svendsen, Clive N

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In Vivo CRISPR/Cas9 Gene Editing Corrects Retinal Dystrophy in the S334ter-3 Rat Model of Autosomal Dominant Retinitis Pigmentosa von Bakondi, Benjamin, Lv, Wenjian, Lu, Bin, Jones, Melissa K, Tsai, Yuchun, Kim, Kevin J, Levy, Rachelle, Akhtar, Aslam Abbasi, Breunig, Joshua J, Svendsen, Clive N, Wang, Shaomei

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An isogenic blood–brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells von Canfield, Scott G., Stebbins, Matthew J., Morales, Bethsymarie Soto, Asai, Shusaku W., Vatine, Gad D., Svendsen, Clive N., Palecek, Sean P., Shusta, Eric V.

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Concise Review: Stem Cells for Corneal Wound Healing von Saghizadeh, Mehrnoosh, Kramerov, Andrei A., Svendsen, Clive N., Ljubimov, Alexander V.

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G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD von Coyne, Alyssa N., Zaepfel, Benjamin L., Hayes, Lindsey, Fitchman, Boris, Salzberg, Yuval, Luo, En-Ching, Bowen, Kelly, Trost, Hannah, Aigner, Stefan, Rigo, Frank, Yeo, Gene W., Harel, Amnon, Svendsen, Clive N., Sareen, Dhruv, Rothstein, Jeffrey D.

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Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier von Vatine, Gad D., Al-Ahmad, Abraham, Barriga, Bianca K., Svendsen, Soshana, Salim, Ariel, Garcia, Leslie, Garcia, Veronica J., Ho, Ritchie, Yucer, Nur, Qian, Tongcheng, Lim, Ryan G., Wu, Jie, Thompson, Leslie M., Spivia, Weston R., Chen, Zhaohui, Van Eyk, Jennifer, Palecek, Sean P., Refetoff, Samuel, Shusta, Eric V., Svendsen, Clive N.

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Human iPSC-Derived Cardiomyocytes Are Susceptible to SARS-CoV-2 Infection von Sharma, Arun, Garcia, Gustavo, Wang, Yizhou, Plummer, Jasmine T., Morizono, Kouki, Arumugaswami, Vaithilingaraja, Svendsen, Clive N.

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Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy von Sareen, Dhruv, Ebert, Allison D, Heins, Brittany M, McGivern, Jered V, Ornelas, Loren, Svendsen, Clive N

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Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits von Lim, Ryan G., Quan, Chris, Reyes-Ortiz, Andrea M., Lutz, Sarah E., Kedaigle, Amanda J., Gipson, Theresa A., Wu, Jie, Vatine, Gad D., Stocksdale, Jennifer, Casale, Malcolm S., Svendsen, Clive N., Fraenkel, Ernest, Housman, David E., Agalliu, Dritan, Thompson, Leslie M.

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Induced pluripotent stem cells: a new revolution for clinical neurology? von Mattis, Virginia B, PhD, Svendsen, Clive N, Prof

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Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication von Garcia, Gustavo, Sharma, Arun, Ramaiah, Arunachalam, Sen, Chandani, Purkayastha, Arunima, Kohn, Donald B., Parcells, Mark S., Beck, Sebastian, Kim, Heeyoung, Bakowski, Malina A., Kirkpatrick, Melanie G., Riva, Laura, Wolff, Karen C., Han, Brandon, Yuen, Constance, Ulmert, David, Purbey, Prabhat K., Scumpia, Philip, Beutler, Nathan, Rogers, Thomas F., Chatterjee, Arnab K., Gabriel, Gülsah, Bartenschlager, Ralf, Gomperts, Brigitte, Svendsen, Clive N., Betz, Ulrich A.K., Damoiseaux, Robert D., Arumugaswami, Vaithilingaraja

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Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development von Sances, Samuel, Ho, Ritchie, Vatine, Gad, West, Dylan, Laperle, Alex, Meyer, Amanda, Godoy, Marlesa, Kay, Paul S., Mandefro, Berhan, Hatata, Seigo, Hinojosa, Chris, Wen, Norman, Sareen, Dhruv, Hamilton, Geraldine A., Svendsen, Clive N.

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Stem cell transplantation for amyotrophic lateral sclerosis von Baloh, Robert H, Glass, Jonathan D, Svendsen, Clive N

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Multi-lineage Human iPSC-Derived Platforms for Disease Modeling and Drug Discovery von Sharma, Arun, Sances, Samuel, Workman, Michael J., Svendsen, Clive N.

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Synergistic Effects of GDNF and VEGF on Lifespan and Disease Progression in a Familial ALS Rat Model von Krakora, Dan, Mulcrone, Patrick, Meyer, Michael, Lewis, Christina, Bernau, Ksenija, Gowing, Genevieve, Zimprich, Chad, Aebischer, Patrick, Svendsen, Clive N, Suzuki, Masatoshi

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Enhanced Utilization of Induced Pluripotent Stem Cell–Derived Human Intestinal Organoids Using Microengineered Chips von Workman, Michael J, Gleeson, John P, Troisi, Elissa J, Estrada, Hannah Q, Kerns, S. Jordan, Hinojosa, Christopher D, Hamilton, Geraldine A, Targan, Stephan R, Svendsen, Clive N, Barrett, Robert J

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Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids von Workman, Michael J, Troisi, Elissa, Targan, Stephan R, Svendsen, Clive N, Barrett, Robert J

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GDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS von Suzuki, Masatoshi, McHugh, Jacalyn, Tork, Craig, Shelley, Brandon, Klein, Sandra M, Aebischer, Patrick, Svendsen, Clive N

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Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD von Gleeson, John P, Estrada, Hannah Q, Yamashita, Michifumi, Svendsen, Clive N, Targan, Stephan R, Barrett, Robert J

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