IFN-Inducible GTPases in Host Cell Defense von Kim, Bae-Hoon, Shenoy, Avinash R., Kumar, Pradeep, Bradfield, Clinton J., MacMicking, John D.

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Interferon-induced guanylate-binding proteins in inflammasome activation and host defense von Kim, Bae-Hoon, Chee, Jonathan D, Bradfield, Clinton J, Park, Eui-Soon, Kumar, Pradeep, MacMicking, John D

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IFIT1 Exerts Opposing Regulatory Effects on the Inflammatory and Interferon Gene Programs in LPS-Activated Human Macrophages von John, Sinu P., Sun, Jing, Carlson, Rebecca J., Cao, Binh, Bradfield, Clinton J., Song, Jian, Smelkinson, Margery, Fraser, Iain D.C.

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Bactericidal antibiotic treatment induces damaging inflammation via TLR9 sensing of bacterial DNA von Gross, Julia L., Basu, Rahul, Bradfield, Clinton J., Sun, Jing, John, Sinu P., Das, Sanchita, Dekker, John P., Weiss, David S., Fraser, Iain D. C.

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Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol von Dorrington, Michael G, Bradfield, Clinton J, Lack, Justin B, Lin, Bin, Liang, Jonathan J, Starr, Tregei, Ernst, Orna, Gross, Julia L, Sun, Jing, Miller, Alexandra H, Steele-Mortimer, Olivia, Fraser, Iain D C

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Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection von John, Sinu P., Singh, Anju, Sun, Jing, Pierre, Makheni Jean, Alsalih, Lulwah, Lipsey, Crystal, Traore, Ziann, Balcom-Luker, Shenavia, Bradfield, Clinton J., Song, Jian, Markowitz, Tovah E., Smelkinson, Margery, Ferrer, Marc, Fraser, Iain D.C.

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Correction: Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol von Dorrington, Michael G, Bradfield, Clinton J, Lack, Justin B, Lin, Bin, John, Sinu P, Liang, Jonathan J, Starr, Tregei, Ernst, Orna, Gross, Julia L, Sun, Jing, Miller, Alexandra H, Steele-Mortimer, Olivia, Fraser, Iain D. C

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A human apolipoprotein L with detergent-like activity kills intracellular pathogens von Gaudet, Ryan G, Zhu, Shiwei, Halder, Anushka, Kim, Bae-Hoon, Bradfield, Clinton J, Huang, Shuai, Xu, Dijin, Mamiñska, Agnieszka, Nguyen, Thanh Ngoc, Lazarou, Michael, Karatekin, Erdem, Gupta, Kallol, MacMicking, John D

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Crossing the Rubicon: New Roads Lead to Host Defense von Bradfield, Clinton J., Kim, Bae-Hoon, MacMicking, John D.

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Biphasic JNK signaling reveals distinct MAP3K complexes licensing inflammasome formation and pyroptosis von Bradfield, Clinton J., Liang, Jonathan J., Ernst, Orna, John, Sinu P., Sun, Jing, Ganesan, Sundar, de Jesus, Adriana A., Bryant, Clare E., Goldbach-Mansky, Raphaela, Fraser, Iain D. C.

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Native architecture of a human GBP1 defense complex for cell-autonomous immunity to infection von Zhu, Shiwei, Bradfield, Clinton J, Maminska, Agnieszka, Park, Eui-Soon, Kim, Bae-Hoon, Kumar, Pradeep, Huang, Shuai, Kim, Minjeong, Zhang, Yongdeng, Bewersdorf, Joerg, MacMicking, John D

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TCR ligand potency differentially impacts PD-1 inhibitory effects on diverse signaling pathways von Chan, Waipan, Cao, Yuqi M, Zhao, Xiang, Schrom, Edward C, Jia, Dongya, Song, Jian, Sibener, Leah V, Dong, Shen, Fernandes, Ricardo A, Bradfield, Clinton J, Smelkinson, Margery, Kabat, Juraj, Hor, Jyh Liang, Altan-Bonnet, Grégoire, Garcia, K Christopher, Germain, Ronald N

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A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activation von Ernst, Orna, Sun, Jing, Lin, Bin, Banoth, Balaji, Dorrington, Michael G, Liang, Jonathan, Schwarz, Benjamin, Stromberg, Kaitlin A, Katz, Samuel, Vayttaden, Sharat J, Bradfield, Clinton J, Slepushkina, Nadia, Rice, Christopher M, Buehler, Eugen, Khillan, Jaspal S, McVicar, Daniel W, Bosio, Catharine M, Bryant, Clare E, Sutterwala, Fayyaz S, Martin, Scott E, Lal-Nag, Madhu, Fraser, Iain D C

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Efficient electroporation in primary cells with PEDOT:PSS electrodes von Gharia, Asmaysinh A, Bradfield, Clinton J, Jenkins, Elise P W, Fraser, Iain D C, Malliaras, George G

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Evolution of Cell-Autonomous Effector Mechanisms in Macrophages versus Non-Immune Cells von Gaudet, Ryan G, Bradfield, Clinton J, MacMicking, John D

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Biphasic JNK signaling reveals distinct MAP3K complexes licensing inflammasome formation and pyroptosis von Bradfield, Clinton J, Liang, Jonathan J., Ernst, Orna, John, Sinu P., Sun, Jing, Ganesan, Sundar, de Jesus, Adriana A., Bryant, Clare E., Goldbach-Mansky, Raphaela, Fraser, Iain DC

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Correction: Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol von Michael G Dorrington, Clinton J Bradfield, Justin B Lack, Bin Lin, Sinu P John, Jonathan J Liang, Tregei Starr, Orna Ernst, Julia L Gross, Jing Sun, Alexandra H Miller, Olivia Steele-Mortimer, Iain D C Fraser

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A genome-wide screen uncovers broad roles for mitochondrial nucleoside diphosphate kinases in inflammasome activation von Ernst, Orna, Sun, Jing, Lin, Bin, Banoth, Balaji, Dorrington, Michael G., Liang, Jonathan, Schwarz, Benjamin, Stromberg, Kaitlin, Katz, Samuel, Vayttaden, Sharat J., Bradfield, Clinton J., Slepushkina, Nadia, Rice, Christopher M., Buehler, Eugen, Khillan, Jaspal S., McVicar, Daniel W., Bosio, Catharine M., Bryant, Clare E., Sutterwala, Fayyaz S., Martin, Scott, Lal-Nag, Madhu, Fraser, Iain D.C.

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IFN-induced Guanylate Binding Proteins in Inflammasome Activation and Host Defense von Kim, Bae-Hoon, Chee, Jonathan D., Bradfield, Clinton J., Park, Eui-Soon, Kumar, Pradeep, MacMicking, John D.

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IFN-inducible GTPases in Host Defense von Kim, Bae-Hoon, Shenoy, Avinash R., Kumar, Pradeep, Bradfield, Clinton J., MacMicking, John D.

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