Overcoming barriers to effective immunotherapy: MDSCs, TAMs, and Tregs as mediators of the immunosuppressive microenvironment in head and neck cancer von Davis, Ruth J, Van Waes, Carter, Allen, Clint T

Volltext

Antigen processing and presentation in cancer immunotherapy von Lee, Maxwell Y, Jeon, Jun W, Sievers, Cem, Allen, Clint T

Volltext

Inhibition of USP14 promotes TNFα-induced cell death in head and neck squamous cell carcinoma (HNSCC) von Morgan, Ethan L., Toni, Tiffany, Viswanathan, Ramya, Robbins, Yvette, Yang, Xinping, Cheng, Hui, Gunti, Sreenivasulu, Huynh, Angel, Sowers, Anastasia L., Mitchell, James B., Allen, Clint T., Chen, Zhong, Van Waes, Carter

Volltext

PD-1 blockade reverses adaptive immune resistance induced by high-dose hypofractionated but not low-dose daily fractionated radiation von Morisada, Megan, Clavijo, Paul E., Moore, Ellen, Sun, Lillian, Chamberlin, Michael, Van Waes, Carter, Hodge, James W., Mitchell, James B., Friedman, Jay, Allen, Clint T.

Volltext

PD-L1 targeting high-affinity NK (t-haNK) cells induce direct antitumor effects and target suppressive MDSC populations von Fabian, Kellsye P, Padget, Michelle R, Donahue, Renee N., Solocinski, Kristen, Robbins, Yvette, Allen, Clint T., Lee, John H., Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Schlom, Jeffrey, Hodge, James W

Volltext

Resistance to CTLA-4 checkpoint inhibition reversed through selective elimination of granulocytic myeloid cells von Clavijo, Paul E, Moore, Ellen C, Chen, Jianhong, Davis, Ruth J, Friedman, Jay, Kim, Young, Van Waes, Carter, Chen, Zhong, Allen, Clint T

Volltext

The PD‐1 and PD‐L1 pathway in recurrent respiratory papillomatosis von Ahn, Julie, Bishop, Justin A., Roden, Richard B. S., Allen, Clint T., Best, Simon R. A.

Volltext

Human papillomavirus and oropharynx cancer: Biology, detection and clinical implications von Allen, Clint T., Lewis Jr, James S., El-Mofty, Samir K., Haughey, Bruce H., Nussenbaum, Brian

Volltext

Tumor control via targeting PD-L1 with chimeric antigen receptor modified NK cells von Robbins, Yvette, Greene, Sarah, Friedman, Jay, Clavijo, Paul E, Van Waes, Carter, Fabian, Kellsye P, Padget, Michelle R, Abdul Sater, Houssein, Lee, John H, Soon-Shiong, Patrick, Gulley, James, Schlom, Jeffrey, Hodge, James W, Allen, Clint T

Volltext

Antagonist of cIAP1/2 and XIAP enhances anti-tumor immunity when combined with radiation and PD-1 blockade in a syngeneic model of head and neck cancer von Xiao, Roy, Allen, Clint T., Tran, Linda, Patel, Priya, Park, So-Jin, Chen, Zhong, Van Waes, Carter, Schmitt, Nicole C.

Volltext

ASTX660, an antagonist of cIAP1/2 and XIAP, increases antigen processing machinery and can enhance radiation-induced immunogenic cell death in preclinical models of head and neck c... von Ye, Wenda, Gunti, Sreenivasulu, Allen, Clint T., Hong, Youji, Clavijo, Paul E., Van Waes, Carter, Schmitt, Nicole C.

Volltext

WEE1 kinase inhibition reverses G2/M cell cycle checkpoint activation to sensitize cancer cells to immunotherapy von Sun, Lillian, Moore, Ellen, Berman, Rose, Clavijo, Paul E., Saleh, Anthony, Chen, Zhong, Van Waes, Carter, Davies, John, Friedman, Jay, Allen, Clint T.

Volltext

Enhanced neoepitope-specific immunity following neoadjuvant PD-L1 and TGF-β blockade in HPV-unrelated head and neck cancer von Redman, Jason M, Friedman, Jay, Robbins, Yvette, Sievers, Cem, Yang, Xinping, Lassoued, Wiem, Sinkoe, Andrew, Papanicolau-Sengos, Antonios, Lee, Chyi-Chia, Marte, Jennifer L, Turkbey, Evrim, Mydlarz, Wojtek, Joshi, Arjun, London, Jr, Nyall R, Pierce, Matthew, Taylor, Rodney, Hong, Steven, Nguyen, Andy, Soon-Shiong, Patrick, Schlom, Jeffrey, Gulley, James L, Allen, Clint T

Volltext

Correction to: Augmentation of tumor expression of HLADR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses von Larkin, Riley M, Lopez, Diana C, Robbins, Yvette L, Lassoued, Wiem, Canubas, Kenneth, Warner, Andrew, Karim, Baktiar, Vulikh, Ksenia, Hodge, James W, Floudas, Charalampos S, Gulley, James L, Gallia, Gary L, Allen, Clint T, London, Jr, Nyall R

Volltext

Augmentation of tumor expression of HLA-DR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses von Larkin, Riley M, Lopez, Diana C, Robbins, Yvette L, Lassoued, Wiem, Canubas, Kenneth, Warner, Andrew, Karim, Baktiar, Vulikh, Ksenia, Hodge, James W, Floudas, Charalampos S, Gulley, James L, Gallia, Gary L, Allen, Clint T, London, Jr, Nyall R

Volltext

SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck von Nigam, Nupur, Bernard, Benjamin, Sevilla, Samantha, Kim, Sohyoung, Dar, Mohd Saleem, Tsai, Daniel, Robbins, Yvette, Burkitt, Kyunghee, Sievers, Cem, Allen, Clint T., Bennett, Richard L., Tettey, Theophilus T., Carter, Benjamin, Rinaldi, Lorenzo, Lingen, Mark W., Sater, Houssein, Edmondson, Elijah F., Moshiri, Arfa, Saeed, Abbas, Cheng, Hui, Luo, Xiaolin, Brennan, Kevin, Koparde, Vishal, Chen, Chen, Das, Sudipto, Andresson, Thorkell, Abdelmaksoud, Abdalla, Murali, Madhavi, Sakata, Seiji, Takeuchi, Kengo, Chari, Raj, Nakamura, Yusuke, Uppaluri, Ravindra, Sunwoo, John B., Van Waes, Carter, Licht, Jonathan D., Hager, Gordon L., Saloura, Vassiliki

Volltext

Epigenetic priming of both tumor and NK cells augments antibody-dependent cellular cytotoxicity elicited by the anti-PD-L1 antibody avelumab against multiple carcinoma cell types von Hicks, Kristin C., Fantini, Massimo, Donahue, Renee N., Schwab, Angie, Knudson, Karin M., Tritsch, Sarah R., Jochems, Caroline, Clavijo, Paul E., Allen, Clint T., Hodge, James W., Tsang, Kwong Y., Schlom, Jeffrey, Gameiro, Sofia R.

Volltext

Semaphorin4D Inhibition Improves Response to Immune-Checkpoint Blockade via Attenuation of MDSC Recruitment and Function von Clavijo, Paul E, Friedman, Jay, Robbins, Yvette, Moore, Ellen C, Smith, Ernest, Zauderer, Maurice, Evans, Elizabeth E, Allen, Clint T

Volltext

Determining if T cell antigens are naturally processed and presented on HLA class I molecules von Friedman, Jay, Gunti, Sreenivasulu, Lee, Maxwell, Bai, Ke, Hinrichs, Christian, Allen, Clint T

Volltext

Inhibition of the chemokine receptors CXCR1 and CXCR2 synergizes with docetaxel for effective tumor control and remodeling of the immune microenvironment of HPV-negative head and n... von Horn, Lucas A, Lind, Hanne, Fousek, Kristen, Qin, Haiyan, Rajabian, Nika, Angstadt, Shantel, Hsiao-Sanchez, Nicole, Medina-Enriquez, Miriam M, Kelly, Marcus D, Allen, Clint T, Hammoudeh, Sarah M, Weigert, Roberto, Maeda, Dean Y, Zebala, John A, Palena, Claudia

Volltext