Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors von Pol, Jonathan G., Lévesque, Sarah, Workenhe, Samuel T., Gujar, Shashi, Le Boeuf, Fabrice, Clements, Derek R., Fahrner, Jean-Eudes, Fend, Laetitia, Bell, John C., Mossman, Karen L., Fucikova, Jitka, Spisek, Radek, Zitvogel, Laurence, Kroemer, Guido, Galluzzi, Lorenzo

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TRPM2 ion channel promotes gastric cancer migration, invasion and tumor growth through the AKT signaling pathway von Almasi, Shekoufeh, Sterea, Andra M., Fernando, Wasundara, Clements, Derek R., Marcato, Paola, Hoskin, David W., Gujar, Shashi, El Hiani, Yassine

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Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression von Zengel, James, Wang, Yu Xin, Seo, Jai Woong, Ning, Ke, Hamilton, James N., Wu, Bo, Raie, Marina, Holbrook, Colin, Su, Shiqi, Clements, Derek R., Pillay, Sirika, Puschnik, Andreas S., Winslow, Monte M., Idoyaga, Juliana, Nagamine, Claude M., Sun, Yang, Mahajan, Vinit B., Ferrara, Katherine W., Blau, Helen M., Carette, Jan E.

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The NAD+ Salvage Pathway Supports PHGDH-Driven Serine Biosynthesis von Murphy, J. Patrick, Giacomantonio, Michael A., Paulo, Joao A., Everley, Robert A., Kennedy, Barry E., Pathak, Gopal P., Clements, Derek R., Kim, Youra, Dai, Cathleen, Sharif, Tanveer, Gygi, Steven P., Gujar, Shashi

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Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy von Prokopi, Anastasia, Tripp, Christoph H, Tummers, Bart, Hornsteiner, Florian, Spoeck, Sarah, Crawford, Jeremy Chase, Clements, Derek R, Efremova, Mirjana, Hutter, Katharina, Bellmann, Lydia, Cappellano, Giuseppe, Cadilha, Bruno L, Kobold, Sebastian, Boon, Louis, Ortner, Daniela, Trajanoski, Zlatko, Chen, Suzie, de Gruijl, Tanja D, Idoyaga, Juliana, Green, Douglas R, Stoitzner, Patrizia

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Dendritic Cells in Oncolytic Virus-Based Anti-Cancer Therapy von Kim, Youra, Clements, Derek R, Sterea, Andra M, Jang, Hyun Woo, Gujar, Shashi A, Lee, Patrick W K

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Surfen, a proteoglycan binding agent, reduces inflammation but inhibits remyelination in murine models of Multiple Sclerosis von Warford, Jordan R, Lamport, Anna-Claire, Clements, Derek R, Malone, Alicia, Kennedy, Barry E, Kim, Youra, Gujar, Shashi A, Hoskin, David W, Easton, Alexander S

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Single Amino Acid Differences between Closely Related Reovirus T3D Lab Strains Alter Oncolytic Potency In Vitro and In Vivo von Mohamed, Adil, Clements, Derek R., Gujar, Shashi A., Lee, Patrick W., Smiley, James R., Shmulevitz, Maya

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Newly Recruited CD11b+, GR-1+, Ly6Chigh Myeloid Cells Augment Tumor-Associated Immunosuppression Immediately following the Therapeutic Administration of Oncolytic Reovirus von Clements, Derek R., Sterea, Andra M., Kim, Youra, Helson, Erin, Dean, Cheryl A., Nunokawa, Anna, Coyle, Krysta Mila, Sharif, Tanveer, Marcato, Paola, Gujar, Shashi A., Lee, Patrick W. K.

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Epigenetic Silencing of TAP1 in Aldefluor+ Breast Cancer Stem Cells Contributes to Their Enhanced Immune Evasion von Sultan, Mohammad, Vidovic, Dejan, Paine, Arianne S., Huynh, Thomas T., Coyle, Krysta M., Thomas, Margaret L., Cruickshank, Brianne M., Dean, Cheryl A., Clements, Derek R., Kim, Youra, Lee, Kristen, Gujar, Shashi A., Weaver, Ian C.G., Marcato, Paola

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Inhibition of Pyruvate Dehydrogenase Kinase Enhances the Antitumor Efficacy of Oncolytic Reovirus von Kennedy, Barry E, Murphy, John Patrick, Clements, Derek R, Konda, Prathyusha, Holay, Namit, Kim, Youra, Pathak, Gopal P, Giacomantonio, Michael A, Hiani, Yassine El, Gujar, Shashi

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Therapy-Induced MHC I Ligands Shape Neo-Antitumor CD8 T Cell Responses during Oncolytic Virus-Based Cancer Immunotherapy von Murphy, J. Patrick, Kim, Youra, Clements, Derek R, Konda, Prathyusha, Schuster, Heiko, Kowalewski, Daniel J, Paulo, Joao A, Cohen, Alejandro M, Stevanovic, Stefan, Gygi, Steven P, Gujar, Shashi

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Quantitative Proteome Responses to Oncolytic Reovirus in GM-CSF- and M‑CSF-Differentiated Bone Marrow-Derived Cells von Giacomantonio, Michael A, Sterea, Andra M, Kim, Youra, Paulo, Joao A, Clements, Derek R, Kennedy, Barry E, Bydoun, Moamen J, Shi, Ge, Waisman, David M, Gygi, Steven P, Giacomantonio, Carman A, Murphy, J. Patrick, Gujar, Shashi

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Newly recruited CD11b+, GR-1+, Ly6C(high) myeloid cells augment tumor-associated immunosuppression immediately following the therapeutic administration of oncolytic reovirus von Clements, Derek R, Sterea, Andra M, Kim, Youra, Helson, Erin, Dean, Cheryl A, Nunokawa, Anna, Coyle, Krysta Mila, Sharif, Tanveer, Marcato, Paola, Gujar, Shashi A, Lee, Patrick W K

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Autophagic homeostasis is required for the pluripotency of cancer stem cells von Sharif, Tanveer, Martell, Emma, Dai, Cathleen, Kennedy, Barry E., Murphy, Patrick, Clements, Derek R., Kim, Youra, Lee, Patrick W. K., Gujar, Shashi A.

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Quantitative Temporal in Vivo Proteomics Deciphers the Transition of Virus-Driven Myeloid Cells into M2 Macrophages von Clements, Derek R, Murphy, John Patrick, Sterea, Andra, Kennedy, Barry E, Kim, Youra, Helson, Erin, Almasi, Shekoufeh, Holay, Namit, Konda, Prathyusha, Paulo, Joao A, Sharif, Tanveer, Lee, Patrick W, Weekes, Michael P, Gygi, Steven P, Gujar, Shashi

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All that glitters is not gold: the need to consider desirable and undesirable immune aspects of oncolytic virus therapy von Clements, Derek R, Kim, Youra, Gujar, Shashi A, Lee, Patrick WK

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Autophagic homeostasis is required for the pluripotency of cancer stem cells von Sharif, Tanveer, Martell, Emma, Dai, Cathleen, Kennedy, Barry E., Murphy, Patrick, Clements, Derek R., Youra Kim, Lee, Patrick W. K., Gujar, Shashi A.

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Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial von Sevransky, Jonathan E, Rothman, Richard E, Hager, David N, Bernard, Gordon R, Brown, Samuel M, Buchman, Timothy G, Busse, Laurence W, Coopersmith, Craig M, DeWilde, Christine, Ely, E. Wesley, Eyzaguirre, Lindsay M, Fowler, Alpha A, Gaieski, David F, Gong, Michelle N, Hall, Alex, Hinson, Jeremiah S, Hooper, Michael H, Kelen, Gabor D, Khan, Akram, Levine, Mark A, Lewis, Roger J, Lindsell, Chris J, Marlin, Jessica S, McGlothlin, Anna, Moore, Brooks L, Nugent, Katherine L, Nwosu, Samuel, Polito, Carmen C, Rice, Todd W, Ricketts, Erin P, Rudolph, Caroline C, Sanfilippo, Fred, Viele, Kert, Martin, Greg S, Wright, David W

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Using SiZer to detect thresholds in ecological data von Sonderegger, Derek L, Haonan Wang, William H Clements, Barry R Noon

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