Respiratory flexibility in response to inhibition of cytochrome C oxidase in Mycobacterium tuberculosis von Arora, Kriti, Ochoa-Montaño, Bernardo, Tsang, Patricia S, Blundell, Tom L, Dawes, Stephanie S, Mizrahi, Valerie, Bayliss, Tracy, Mackenzie, Claire J, Cleghorn, Laura A T, Ray, Peter C, Wyatt, Paul G, Uh, Eugene, Lee, Jinwoo, Barry, 3rd, Clifton E, Boshoff, Helena I

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Discovery of a Novel Class of Orally Active Trypanocidal N-Myristoyltransferase Inhibitors von Brand, Stephen, Cleghorn, Laura A. T, McElroy, Stuart P, Robinson, David A, Smith, Victoria C, Hallyburton, Irene, Harrison, Justin R, Norcross, Neil R, Spinks, Daniel, Bayliss, Tracy, Norval, Suzanne, Stojanovski, Laste, Torrie, Leah S, Frearson, Julie A, Brenk, Ruth, Fairlamb, Alan H, Ferguson, Michael A. J, Read, Kevin D, Wyatt, Paul G, Gilbert, Ian H

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Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB von Cleghorn, Laura A. T, Ray, Peter C, Odingo, Joshua, Kumar, Anuradha, Wescott, Heather, Korkegian, Aaron, Masquelin, Thierry, Lopez Moure, Abraham, Wilson, Caroline, Davis, Susan, Huggett, Margaret, Turner, Penelope, Smith, Alasdair, Epemolu, Ola, Zuccotto, Fabio, Riley, Jennifer, Scullion, Paul, Shishikura, Yoko, Ferguson, Liam, Rullas, Joaquin, Guijarro, Laura, Read, Kevin D, Green, Simon R, Hipskind, Phil, Parish, Tanya, Wyatt, Paul G

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N -myristoyltransferase inhibitors as new leads to treat sleeping sickness von Cleghorn, Laura A. T, Torrie, Leah S, Frearson, Julie A, Guther, M. Lucia S, Smid, Ondrej, Smith, Deborah F, Stojanovski, Laste, Wilkinson, Anthony J, Wyatt, Paul G, Brannigan, James A, Hui, Raymond, Brand, Stephen, Raimi, Olawale G, Brenk, Ruth, Robinson, David A, Hodgkinson, Michael, Ferguson, Michael A. J, Hallyburton, Irene, Mpamhanga, Chidochangu P, Gilbert, Ian H, McElroy, Stuart P, van Aalten, Daan M. F, Qiu, Wei, Read, Kevin D, Price, Helen P, Fairlamb, Alan H

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Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs von Green, Simon R., Davis, Susan H., Damerow, Sebastian, Engelhart, Curtis A., Mathieson, Michael, Baragaña, Beatriz, Robinson, David A., Tamjar, Jevgenia, Dawson, Alice, Tamaki, Fabio K., Buchanan, Kirsteen I., Post, John, Dowers, Karen, Shepherd, Sharon M., Jansen, Chimed, Zuccotto, Fabio, Gilbert, Ian H., Epemolu, Ola, Riley, Jennifer, Stojanovski, Laste, Osuna-Cabello, Maria, Pérez-Herrán, Esther, Rebollo, María José, Guijarro López, Laura, Casado Castro, Patricia, Camino, Isabel, Kim, Heather C., Bean, James M., Nahiyaan, Navid, Rhee, Kyu Y., Wang, Qinglan, Tan, Vee Y., Boshoff, Helena I. M., Converse, Paul J., Li, Si-Yang, Chang, Yong S., Fotouhi, Nader, Upton, Anna M., Nuermberger, Eric L., Schnappinger, Dirk, Read, Kevin D., Encinas, Lourdes, Bates, Robert H., Wyatt, Paul G., Cleghorn, Laura A. T.

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From On-Target to Off-Target Activity: Identification and Optimisation of Trypanosoma brucei GSK3 Inhibitors and Their Characterisation as Anti-Trypanosoma brucei Drug Discovery Le... von Woodland, Andrew, Grimaldi, Raffaella, Luksch, Torsten, Cleghorn, Laura A. T., Ojo, Kayode K., Van Voorhis, Wesley C., Brenk, Ruth, Frearson, Julie A., Gilbert, Ian H., Wyatt, Paul G.

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Investigation of Trypanothione Reductase as a Drug Target in Trypanosoma brucei von Spinks, Daniel, Shanks, Emma J., Cleghorn, Laura A. T., McElroy, Stuart, Jones, Deuan, James, Daniel, Fairlamb, Alan H., Frearson, Julie A., Wyatt, Paul G., Gilbert, Ian H.

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Peptidyl tRNA Hydrolase Is Required for Robust Prolyl-tRNA Turnover in Mycobacterium tuberculosis von Tomasi, Francesca G, Schweber, Jessica T P, Kimura, Satoshi, Zhu, Junhao, Cleghorn, Laura A T, Davis, Susan H, Green, Simon R, Waldor, Matthew K, Rubin, Eric J

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Discovery of Indoline-2-carboxamide Derivatives as a New Class of Brain-Penetrant Inhibitors of Trypanosoma brucei von Cleghorn, Laura A. T., Albrecht, Sébastien, Stojanovski, Laste, Simeons, Frederick R. J., Norval, Suzanne, Kime, Robert, Collie, Iain T., De Rycker, Manu, Campbell, Lorna, Hallyburton, Irene, Frearson, Julie A., Wyatt, Paul G., Read, Kevin D., Gilbert, Ian H.

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Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of Mycobacterium tuberculosis Growth von Ray, Peter C, Huggett, Margaret, Turner, Penelope A, Taylor, Malcolm, Cleghorn, Laura A. T, Early, Julie, Kumar, Anuradha, Bonnett, Shilah A, Flint, Lindsay, Joerss, Douglas, Johnson, James, Korkegian, Aaron, Mullen, Steven, Moure, Abraham L, Davis, Susan H, Murugesan, Dinakaran, Mathieson, Michael, Caldwell, Nicola, Engelhart, Curtis A, Schnappinger, Dirk, Epemolu, Ola, Zuccotto, Fabio, Riley, Jennifer, Scullion, Paul, Stojanovski, Laste, Massoudi, Lisa, Robertson, Gregory T, Lenaerts, Anne J, Freiberg, Gail, Kempf, Dale J, Masquelin, Thierry, Hipskind, Philip A, Odingo, Joshua, Read, Kevin D, Green, Simon R, Wyatt, Paul G, Parish, Tanya

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Correction for Arora et al., "Respiratory Flexibility in Response to Inhibition of Cytochrome c Oxidase in Mycobacterium tuberculosis " von Arora, Kriti, Ochoa-Montaño, Bernardo, Tsang, Patricia S, Blundell, Tom L, Dawes, Stephanie S, Mizrahi, Valerie, Bayliss, Tracy, Mackenzie, Claire J, Cleghorn, Laura A T, Ray, Peter C, Wyatt, Paul G, Uh, Eugene, Lee, Jinwoo, Barry, 3rd, Clifton E, Boshoff, Helena I

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Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase Library von Woodland, Andrew, Thompson, Stephen, Cleghorn, Laura A. T., Norcross, Neil, De Rycker, Manu, Grimaldi, Raffaella, Hallyburton, Irene, Rao, Bhavya, Norval, Suzanne, Stojanovski, Laste, Brun, Reto, Kaiser, Marcel, Frearson, Julie A., Gray, David W., Wyatt, Paul G., Read, Kevin D., Gilbert, Ian H.

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Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static–Cidal Screening of Analogues von Cleghorn, Laura A. T., Wall, Richard J., Albrecht, Sébastien, MacGowan, Stuart A., Norval, Suzanne, De Rycker, Manu, Woodland, Andrew, Spinks, Daniel, Thompson, Stephen, Patterson, Stephen, Corpas Lopez, Victoriano, Dey, Gourav, Collie, Iain T., Hallyburton, Irene, Kime, Robert, Simeons, Frederick R. C., Stojanovski, Laste, Frearson, Julie A., Wyatt, Paul G., Read, Kevin D., Gilbert, Ian H., Wyllie, Susan

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Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis von Thomas, Michael G, De Rycker, Manu, Ajakane, Myriam, Albrecht, Sébastian, Álvarez-Pedraglio, Ana Isabel, Boesche, Markus, Brand, Stephen, Campbell, Lorna, Cantizani-Perez, Juan, Cleghorn, Laura A.T, Copley, Royston C.B, Crouch, Sabrinia D, Daugan, Alain, Drewes, Gerard, Ferrer, Santiago, Ghidelli-Disse, Sonja, Gonzalez, Silvia, Gresham, Stephanie L, Hill, Alan P, Hindley, Sean J, Lowe, Rhiannon M, MacKenzie, Claire J, MacLean, Lorna, Manthri, Sujatha, Martin, Franck, Miguel-Siles, Juan, Nguyen, Van Loc, Norval, Suzanne, Osuna-Cabello, Maria, Woodland, Andrew, Patterson, Stephen, Pena, Imanol, Quesada-Campos, Maria Teresa, Reid, Iain H, Revill, Charlotte, Riley, Jennifer, Ruiz-Gomez, Jose Ramon, Shishikura, Yoko, Simeons, Frederick R.C, Smith, Alasdair, Smith, Victoria C, Spinks, Daniel, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Underwood, Tim, Gray, David W, Fiandor, Jose M, Gilbert, Ian H, Wyatt, Paul G, Read, Kevin D, Miles, Timothy J

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Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis von Park, Yumi, Pacitto, Angela, Bayliss, Tracy, Cleghorn, Laura A. T, Wang, Zhe, Hartman, Travis, Arora, Kriti, Ioerger, Thomas R, Sacchettini, Jim, Rizzi, Menico, Donini, Stefano, Blundell, Tom L, Ascher, David B, Rhee, Kyu, Breda, Ardala, Zhou, Nian, Dartois, Veronique, Jonnala, Surendranadha Reddy, Via, Laura E, Mizrahi, Valerie, Epemolu, Ola, Stojanovski, Laste, Simeons, Fred, Osuna-Cabello, Maria, Ellis, Lucy, MacKenzie, Claire J, Smith, Alasdair R. C, Davis, Susan H, Murugesan, Dinakaran, Buchanan, Kirsteen I, Turner, Penelope A, Huggett, Margaret, Zuccotto, Fabio, Rebollo-Lopez, Maria Jose, Lafuente-Monasterio, Maria Jose, Sanz, Olalla, Diaz, Gracia Santos, Lelièvre, Joël, Ballell, Lluis, Selenski, Carolyn, Axtman, Matthew, Ghidelli-Disse, Sonja, Pflaumer, Hannah, Bösche, Markus, Drewes, Gerard, Freiberg, Gail M, Kurnick, Matthew D, Srikumaran, Myron, Kempf, Dale J, Green, Simon R, Ray, Peter C, Read, Kevin, Wyatt, Paul, Barry, Clifton E, Boshoff, Helena I

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Back Cover: From On-Target to Off-Target Activity: Identification and Optimisation of Trypanosoma brucei GSK3 Inhibitors and Their Characterisation as Anti-Trypanosoma brucei Drug... von Woodland, Andrew, Grimaldi, Raffaella, Luksch, Torsten, Cleghorn, Laura A. T., Ojo, Kayode K., Van Voorhis, Wesley C., Brenk, Ruth, Frearson, Julie A., Gilbert, Ian H., Wyatt, Paul G.

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Identification of Inhibitors of the Leishmania cdc2-Related Protein Kinase CRK3 von Cleghorn, Laura A. T., Woodland, Andrew, Collie, Iain T., Torrie, Leah S., Norcross, Neil, Luksch, Torsten, Mpamhanga, Chido, Walker, Roderick G., Mottram, Jeremy C., Brenk, Ruth, Frearson, Julie A., Gilbert, Ian H., Wyatt, Paul G.

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Bimetallic catalytic synthesis of annelated benzazepines von Cleghorn, Laura A T, Grigg, Ronald, Kilner, Colin, MacLachlan, William S, Sridharan, Visvanthar

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Optimisation of the Anti-Trypanosoma brucei Activity of the Opioid Agonist U50488 von Smith, Victoria C., Cleghorn, Laura A. T., Woodland, Andrew, Spinks, Daniel, Hallyburton, Irene, Collie, Iain T., Yi Mok, N., Norval, Suzanne, Brenk, Ruth, Fairlamb, Alan H., Frearson, Julie A., Read, Kevin D., Gilbert, Ian H., Wyatt, Paul G.

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Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues von Cleghorn, Laura AT, Wall, Richard J, Albrecht, Sébastien, MacGowan, Stuart A, Norval, Suzanne, De Rycker, Manu, Woodland, Andrew, Spinks, Daniel, Thompson, Stephen, Patterson, Stephen, Corpas Lopez, Victoriano, Dey, Gourav, Collie, Iain T, Hallyburton, Irene, Kime, Robert, Simeons, Frederick RC, Stojanovski, Laste, Frearson, Julie A, Wyatt, Paul G, Read, Kevin D, Gilbert, Ian H, Wyllie, Susan

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