P1477: CHARACTERIZING SICKLE CELL DISEASE AND BURDEN OF ILLNESS IN THE UNITED STATES OF AMERICA: A RETROSPECTIVE ANALYSIS OF REAL‐WORLD DATA von Clay, E. L. J., Paulose, J., Rowe, C., Tierney, M., Zhou, Y., Pattipaka, T., Wormser, D., Fermont, J. M.

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A Role for GIBBERELLIN 2-OXIDASE6 and Gibberellins in Regulating Nectar Production von Wiesen, Lisa B., Bender, Ricci L., Paradis, Travis, Larson, Alexie, Perera, M. Ann D.N., Nikolau, Basil J., Olszewski, Neil E., Carter, Clay J.

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Past climates inform our future von Tierney, Jessica E., Poulsen, Christopher J., Montanez, Isabel P., Bhattacharya, Tripti, Feng, Ran, Ford, Heather L., Honisch, Barbel, Inglis, Gordon N., Petersen, Sierra V., Sagoo, Navjit, Tabor, Clay R., Thirumalai, Kaustubh, Zhu, Jiang, Burls, Natalie J., Foster, Gavin L., Godderis, Yves, Huber, Brian T., Ivany, Linda C., Turner, Sandra Kirtland, Lunt, Daniel J., McElwain, Jennifer C., Mills, Benjamin J. W., Otto-Bliesner, Bette L., Ridgwell, Andy, Zhang, Yi Ge

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Discovery and spectroscopy of the young jovian planet 51 Eri b with the Gemini Planet Imager von Macintosh, B., Graham, J. R., Barman, T., De Rosa, R. J., Konopacky, Q., Marley, M. S., Marois, C., Nielsen, E. L., Pueyo, L., Rajan, A., Rameau, J., Saumon, D., Wang, J. J., Patience, J., Ammons, M., Arriaga, P., Artigau, E., Beckwith, S., Brewster, J., Bruzzone, S., Bulger, J., Burningham, B., Burrows, A. S., Chen, C., Chiang, E., Chilcote, J. K., Dawson, R. I., Dong, R., Doyon, R., Draper, Z. H., Duchêne, G., Esposito, T. M., Fabrycky, D., Fitzgerald, M. P., Follette, K. B., Fortney, J. J., Gerard, B., Goodsell, S., Greenbaum, A. Z., Hibon, P., Hinkley, S., Cotten, T. H., Hung, L.-W., Ingraham, P., Johnson-Groh, M., Kalas, P., Lafreniere, D., Larkin, J. E., Lee, J., Line, M., Long, D., Maire, J., Marchis, F., Matthews, B. C., Max, C. E., Metchev, S., Millar-Blanchaer, M. A., Mittal, T., Morley, C. V., Morzinski, K. M., Murray-Clay, R., Oppenheimer, R., Palmer, D. W., Patel, R., Perrin, M. D., Poyneer, L. A., Rafikov, R. R., Rantakyrö, F. T., Rice, E. L., Rojo, P., Rudy, A. R., Ruffio, J.-B., Ruiz, M. T., Sadakuni, N., Saddlemyer, L., Salama, M., Savransky, D., Schneider, A. C., Sivaramakrishnan, A., Song, I., Soummer, R., Thomas, S., Vasisht, G., Wallace, J. K., Ward-Duong, K., Wiktorowicz, S. J., Wolff, S. G., Zuckerman, B.

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Adaptation to Stressors by Systemic Protein Amyloidogenesis von Audas, Timothy E., Audas, Danielle E., Jacob, Mathieu D., Ho, J.J. David, Khacho, Mireille, Wang, Miling, Perera, J. Kishan, Gardiner, Caroline, Bennett, Clay A., Head, Trajen, Kryvenko, Oleksandr N., Jorda, Mercé, Daunert, Sylvia, Malhotra, Arun, Trinkle-Mulcahy, Laura, Gonzalgo, Mark L., Lee, Stephen

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Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice von Ridaura, Vanessa K., Faith, Jeremiah J., Rey, Federico E., Cheng, Jiye, Duncan, Alexis E., Kau, Andrew L., Griffin, Nicholas W., Lombard, Vincent, Henrissat, Bernard, Bain, James R., Muehlbauer, Michael J., Ilkayeva, Olga, Semenkovich, Clay F., Funai, Katsuhiko, Hayashi, David K., Lyle, Barbara J., Martini, Margaret C., Ursell, Luke K., Clemente, Jose C., Van Treuren, William, Walters, William A., Knight, Rob, Newgard, Christopher B., Heath, Andrew C., Gordon, Jeffrey I.

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Baseline levels and longitudinal changes in plasma Aβ42/40 among Black and white individuals von Xiong, Chengjie, Luo, Jingqin, Wolk, David A., Shaw, Leslie M., Roberson, Erik D., Murchison, Charles F., Henson, Rachel L., Benzinger, Tammie L. S., Bui, Quoc, Agboola, Folasade, Grant, Elizabeth, Gremminger, Emily N., Moulder, Krista L., Geldmacher, David S., Clay, Olivio J., Babulal, Ganesh, Cruchaga, Carlos, Holtzman, David M., Bateman, Randall J., Morris, John C., Schindler, Suzanne E.

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Many Analysts, One Data Set: Making Transparent How Variations in Analytic Choices Affect Results von Silberzahn, R., Uhlmann, E. L., Martin, D. P., Anselmi, P., Aust, F., Awtrey, E., Bahník, Š., Bai, F., Bannard, C., Bonnier, E., Carlsson, R., Cheung, F., Christensen, G., Clay, R., Craig, M. A., Dalla Rosa, A., Dam, L., Evans, M. H., Flores Cervantes, I., Fong, N., Gamez-Djokic, M., Glenz, A., Gordon-McKeon, S., Heaton, T. J., Hederos, K., Heene, M., Hofelich Mohr, A. J., Högden, F., Hui, K., Johannesson, M., Kalodimos, J., Kaszubowski, E., Kennedy, D. M., Lei, R., Lindsay, T. A., Liverani, S., Madan, C. R., Molden, D., Molleman, E., Morey, R. D., Mulder, L. B., Nijstad, B. R., Pope, N. G., Pope, B., Prenoveau, J. M., Rink, F., Robusto, E., Roderique, H., Sandberg, A., Schlüter, E., Schönbrodt, F. D., Sherman, M. F., Sommer, S. A., Sotak, K., Spain, S., Spörlein, C., Stafford, T., Stefanutti, L., Tauber, S., Ullrich, J., Vianello, M., Wagenmakers, E.-J., Witkowiak, M., Yoon, S., Nosek, B. A.

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Goal-directed Hemostatic Resuscitation of Trauma-induced Coagulopathy: A Pragmatic Randomized Clinical Trial Comparing a Viscoelastic Assay to Conventional Coagulation Assays von Gonzalez, Eduardo, Moore, Ernest E, Moore, Hunter B, Chapman, Michael P, Chin, Theresa L, Ghasabyan, Arsen, Wohlauer, Max V, Barnett, Carlton C, Bensard, Denis D, Biffl, Walter L, Burlew, Clay C, Johnson, Jeffrey L, Pieracci, Fredric M, Jurkovich, Gregory J, Banerjee, Anirban, Silliman, Christopher C, Sauaia, Angela

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Amphotericin forms an extramembranous and fungicidal sterol sponge von Anderson, Thomas M, Clay, Mary C, Cioffi, Alexander G, Diaz, Katrina A, Hisao, Grant S, Tuttle, Marcus D, Nieuwkoop, Andrew J, Comellas, Gemma, Maryum, Nashrah, Wang, Shu, Uno, Brice E, Wildeman, Erin L, Gonen, Tamir, Rienstra, Chad M, Burke, Martin D

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Tree mycorrhizal type predicts within‐site variability in the storage and distribution of soil organic matter von Craig, Matthew E., Turner, Benjamin L., Liang, Chao, Clay, Keith, Johnson, Daniel J., Phillips, Richard P.

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Measurement of the cosmic-ray energy spectrum above 2.5 x 10(18) eV using the Pierre Auger Observatory von Aab, A., Abreu, P., Aglietta, M., Albury, J. M., Allekotte, Almela, A., Castillo, J. Alvarez, Alvarez-Muniz, J., Batista, R. Alves, Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Ferreira, P. R. Araujo, Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Luz, R. J. Barreira, Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Bister, T., Biteau, J., Blanco, A., Blazek, J., Bleve, C., Bohacova, M., Boncioli, D., Bonifazi, C., Arbeletche, L. Bonneau, Borodai, N., Botti, A. M., Brack, J., Bretz, T., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Calcagni, L., Cancio, A., Canfora, F., Caracas, Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Choi, K., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. Cobos, Colalillo, R., Coleman, A., Coluccia, M. R., Conceicao, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., de Almeida, R. M., de Jesus, J., de Jong, S. J., De Mauro, G., Neto, J. R. T. de Mello, De Mitri, de Oliveira, J., Franco, D. de Oliveira, de Souza, De Vito, E., Debatin, J., del Rio, M., Deligny, O., Dembinski, H., Dhital, N., Di Giulio, C., Di Matteo, A., Castro, M. L. Diaz, Dobrigkeit, C., D'Olivo, J. C., Dorosti, Q.

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Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor von Murphy, Andrew J., Chen, Xiang, Pinto, Emilia M., Williams, Justin S., Clay, Michael R., Pounds, Stanley B., Cao, Xueyuan, Shi, Lei, Lin, Tong, Neale, Geoffrey, Morton, Christopher L., Woolard, Mary A., Mulder, Heather L., Gil, Hyea Jin, Rehg, Jerold E., Billups, Catherine A., Harlow, Matthew L., Dome, Jeffrey S., Houghton, Peter J., Easton, John, Zhang, Jinghui, George, Rani E., Zambetti, Gerard P., Davidoff, Andrew M.

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Features of the Energy Spectrum of Cosmic Rays above 2.5 x 1018 eV Using the Pierre Auger Observatory von Aab, A., Abreu, P., Aglietta, M., Albury, J. M., Allekotte, Almela, A., Alvarez Castillo, J., Alvarez-Muniz, J., Batista, R. Alves, Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Ferreira, P. R. Araujo, Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Luz, R. J. Barreira, Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Bister, T., Biteau, J., Blanco, A., Blazek, J., Bleve, C., Bohacova, M., Boncioli, D., Bonifazi, C., Arbeletche, L. Bonneau, Borodai, N., Botti, A. M., Brack, J., Bretz, T., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Calcagni, L., Cancio, A., Canfora, F., Caracas, Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Choi, K., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. Cobos, Colalillo, R., Coleman, A., Coluccia, M. R., Conceicao, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., de Almeida, R. M., de Jesus, J., de Jong, S. J., De Mauro, G., de Mello Neto, J. R. T., De Mitri, de Oliveira, J., Franco, D. de Oliveira, de Souza, De Vito, E., Debatin, J., del Rio, M., Deligny, O., Dembinski, H., Dhital, N., Di Giulio, C., Di Matteo, A., Castro, M. L. Diaz, Dobrigkeit, C., D'Olivo, J. C., Dorosti, Q.

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Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs von Londin, Eric, Loher, Phillipe, Telonis, Aristeidis G., Quann, Kevin, Clark, Peter, Jing, Yi, Hatzimichael, Eleftheria, Kirino, Yohei, Honda, Shozo, Lally, Michelle, Ramratnam, Bharat, Comstock, Clay E. S., Knudsen, Karen E., Gomella, Leonard, Spaeth, George L., Hark, Lisa, Katz, L. Jay, Witkiewicz, Agnieszka, Rostami, Abdolmohamad, Jimenez, Sergio A., Hollingsworth, Michael A., Yeh, Jen Jen, Shaw, Chad A., McKenzie, Steven E., Bray, Paul, Nelson, Peter T., Zupo, Simona, Van Roosbroeck, Katrien, Keating, Michael J., Calin, George A., Yeo, Charles, Jimbo, Masaya, Cozzitorto, Joseph, Brody, Jonathan R., Delgrosso, Kathleen, Mattick, John S., Fortina, Paolo, Rigoutsos, Isidore

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Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment von Ulland, Tyler K., Jain, Nidhi, Hornick, Emma E., Elliott, Eric I., Clay, Gwendolyn M., Sadler, Jeffrey J., Mills, Kathleen A. M., Janowski, Ann M., Volk, A. Paige Davis, Wang, Kai, Legge, Kevin L., Gakhar, Lokesh, Bourdi, Mohammed, Ferguson, Polly J., Wilson, Mary E., Cassel, Suzanne L., Sutterwala, Fayyaz S.

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Measurement of the cosmic-ray energy spectrum above 2.5 × 1018 eV using the Pierre Auger Observatory von Aab, A

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Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region von Aneas, Ivy, Decker, Donna C., Howard, Chanie L., Sobreira, Débora R., Sakabe, Noboru J., Blaine, Kelly M., Stein, Michelle M., Hrusch, Cara L., Montefiori, Lindsey E., Tena, Juan, Magnaye, Kevin M., Clay, Selene M., Gern, James E., Jackson, Daniel J., Altman, Matthew C., Naureckas, Edward T., Hogarth, Douglas K., White, Steven R., Gomez-Skarmeta, Jose Luis, Schoetler, Nathan, Ober, Carole, Sperling, Anne I., Nóbrega, Marcelo A.

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Targeting MYCN in neuroblastoma by BET bromodomain inhibition von Puissant, Alexandre, Frumm, Stacey M, Alexe, Gabriela, Bassil, Christopher F, Qi, Jun, Chanthery, Yvan H, Nekritz, Erin A, Zeid, Rhamy, Gustafson, William Clay, Greninger, Patricia, Garnett, Matthew J, McDermott, Ultan, Benes, Cyril H, Kung, Andrew L, Weiss, William A, Bradner, James E, Stegmaier, Kimberly

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Nanotools for Neuroscience and Brain Activity Mapping von Alivisatos, A. Paul, Andrews, Anne M, Boyden, Edward S, Chun, Miyoung, Church, George M, Deisseroth, Karl, Donoghue, John P, Fraser, Scott E, Lippincott-Schwartz, Jennifer, Looger, Loren L, Masmanidis, Sotiris, McEuen, Paul L, Nurmikko, Arto V, Park, Hongkun, Peterka, Darcy S, Reid, Clay, Roukes, Michael L, Scherer, Axel, Schnitzer, Mark, Sejnowski, Terrence J, Shepard, Kenneth L, Tsao, Doris, Turrigiano, Gina, Weiss, Paul S, Xu, Chris, Yuste, Rafael, Zhuang, Xiaowei

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