Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer von Patra, Krushna C., Wang, Qi, Bhaskar, Prashanth T., Miller, Luke, Wang, Zebin, Wheaton, Will, Chandel, Navdeep, Laakso, Markku, Muller, William J., Allen, Eric L., Jha, Abhishek K., Smolen, Gromoslaw A., Clasquin, Michelle F., Robey, R. Brooks, Hay, Nissim

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MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis von Marjon, Katya, Cameron, Michael J., Quang, Phong, Clasquin, Michelle F., Mandley, Everton, Kunii, Kaiko, McVay, Michael, Choe, Sung, Kernytsky, Andrew, Gross, Stefan, Konteatis, Zenon, Murtie, Joshua, Blake, Michelle L., Travins, Jeremy, Dorsch, Marion, Biller, Scott A., Marks, Kevin M.

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Metabolomic Analysis via Reversed-Phase Ion-Pairing Liquid Chromatography Coupled to a Stand Alone Orbitrap Mass Spectrometer von Lu, Wenyun, Clasquin, Michelle F, Melamud, Eugene, Amador-Noguez, Daniel, Caudy, Amy A, Rabinowitz, Joshua D

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Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13 von Liu, Shenping, Sommese, Ruth F., Nedoma, Nicole L., Stevens, Lucy Mae, Dutra, Jason K., Zhang, Liying, Edmonds, David J., Wang, Yang, Garnsey, Michelle, Clasquin, Michelle F.

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Murine HSD17β13 does not control liver steatosis and modestly impacts fibrosis in a sex- and diet-specific manner von Crane, Justin D., Barrandon, Ornella, Faherty, Bryan, Gorgoglione, Matt, Crowley, Collin, Morin, Jeff, Ross, Trenton T., Shimkonis, Jackson, Li, Dongmei, Hirenallur-Shanthappa, Dinesh, Boucher, Magalie, Ahn, Youngwook, Clasquin, Michelle F.

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Differential Aspartate Usage Identifies a Subset of Cancer Cells Particularly Dependent on OGDH von Allen, Eric L., Ulanet, Danielle B., Pirman, David, Mahoney, Christopher E., Coco, John, Si, Yaguang, Chen, Ying, Huang, Lingling, Ren, Jinmin, Choe, Sung, Clasquin, Michelle F., Artin, Erin, Fan, Zi Peng, Cianchetta, Giovanni, Murtie, Joshua, Dorsch, Marion, Jin, Shengfang, Smolen, Gromoslaw A.

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Riboneogenesis in Yeast von Clasquin, Michelle F., Melamud, Eugene, Singer, Alexander, Gooding, Jessica R., Xu, Xiaohui, Dong, Aiping, Cui, Hong, Campagna, Shawn R., Savchenko, Alexei, Yakunin, Alexander F., Rabinowitz, Joshua D., Caudy, Amy A.

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Pharmacologic inhibition of ketohexokinase prevents fructose-induced metabolic dysfunction von Gutierrez, Jemy A., Liu, Wei, Perez, Sylvie, Xing, Gang, Sonnenberg, Gabriele, Kou, Kou, Blatnik, Matt, Allen, Richard, Weng, Yan, Vera, Nicholas B., Chidsey, Kristin, Bergman, Arthur, Somayaji, Veena, Crowley, Collin, Clasquin, Michelle F., Nigam, Anu, Fulham, Melissa A., Erion, Derek M., Ross, Trenton T., Esler, William P., Magee, Thomas V., Pfefferkorn, Jeffrey A., Bence, Kendra K., Birnbaum, Morris J., Tesz, Gregory J.

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Coupling Mixed Mode Chromatography/ESI Negative MS Detection with Message-Passing Neural Network Modeling for Enhanced Metabolome Coverage and Structural Identification von Xing, Gang, Sresht, Vishnu, Sun, Zhongyuan, Shi, Yuji, Clasquin, Michelle F.

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LC-MS data processing with MAVEN: a metabolomic analysis and visualization engine von Clasquin, Michelle F, Melamud, Eugene, Rabinowitz, Joshua D

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Serine catabolism generates liver NADPH and supports hepatic lipogenesis von Zhang, Zhaoyue, TeSlaa, Tara, Xu, Xincheng, Zeng, Xianfeng, Yang, Lifeng, Xing, Gang, Tesz, Gregory J., Clasquin, Michelle F., Rabinowitz, Joshua D.

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1922-P: Branched-Chain Ketoacid Dehydrogenase Kinase Inhibition Acutely Improves Glycemia and Alters the Response to Feeding in Mice von BOLLINGER, ELIZA, SIDDALL, CHARLES PARKER, GREIZER, TIMOTHY, LIBERA, JENNA L., HARIRI, GHAZAL, PASHOS, EVANTHIA E., SHIPSTONE, ARUN, HADJIPANAYIS, ANGELA, SUN, ZHONGYUAN, XING, GANG, CLASQUIN, MICHELLE F., ZHANG, BEI B., MILLER, RUSSELL A., ROTH FLACH, RACHEL

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Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer von Patra, Krushna C., Wang, Qi, Bhaskar, Prashanth T., Miller, Luke, Wang, Zebin, Wheaton, Will, Chandel, Navdeep, Laakso, Markku, Muller, William J., Allen, Eric L., Jha, Abhishek K., Smolen, Gromoslaw A., Clasquin, Michelle F., Robey, R. Brooks, Hay, Nissim

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Towards a comprehensive understanding of cellular metabolism von Rabinowitz, Joshua, Xu, Yifan, Clasquin, Michelle F, Johnson, Sarah, Lu, Wenyun, Campagna, Shawn R, Yakunin, Alexander F, Caudy, Amy A, Letisse, Fabien

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