Intracellular Action of a Secreted Peptide Required for Fungal Virulence von Homer, Christina M., Summers, Diana K., Goranov, Alexi I., Clarke, Starlynn C., Wiesner, Darin L., Diedrich, Jolene K., Moresco, James J., Toffaletti, Dena, Upadhya, Rajendra, Caradonna, Ippolito, Petnic, Sarah, Pessino, Veronica, Cuomo, Christina A., Lodge, Jennifer K., Perfect, John, Yates, John R., Nielsen, Kirsten, Craik, Charles S., Madhani, Hiten D.

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TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity von Ugamraj, Harshad S., Dang, Kevin, Ouisse, Laure-Hélène, Buelow, Benjamin, Chini, Eduardo N., Castello, Giulia, Allison, James, Clarke, Starlynn C, Davison, Laura M., Buelow, Roland, Deng, Rong, Iyer, Suhasini, Schellenberger, Ute, Manika, Sankar N., Bijpuria, Shipra, Musnier, Astrid, Poupon, Anne, Cuturi, Maria Cristina, van Schooten, Wim, Dalvi, Pranjali

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Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and Virulence von Clarke, Starlynn C, Dumesic, Phillip A, Homer, Christina M, O'Donoghue, Anthony J, La Greca, Florencia, Pallova, Lenka, Majer, Pavel, Madhani, Hiten D, Craik, Charles S

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Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies von Clarke, Starlynn C, Ma, Biao, Trinklein, Nathan D, Schellenberger, Ute, Osborn, Michael J, Ouisse, Laure-Hélène, Boudreau, Andrew, Davison, Laura M, Harris, Katherine E, Ugamraj, Harshad S, Balasubramani, Aarti, Dang, Kevin H, Jorgensen, Brett, Ogana, Heather Anne N, Pham, Duy T, Pratap, Payal P, Sankaran, Preethi, Anegon, Ignacio, van Schooten, Wim C, Brüggemann, Marianne, Buelow, Roland, Force Aldred, Shelley

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Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release von Dang, Kevin, Castello, Giulia, Clarke, Starlynn C, Li, Yuping, Balasubramani, Aarti, Boudreau, Andrew, Davison, Laura, Harris, Katherine E, Pham, Duy, Sankaran, Preethi, Ugamraj, Harshad S, Deng, Rong, Kwek, Serena, Starzinski, Alec, Iyer, Suhasini, van Schooten, Wim, Schellenberger, Ute, Sun, Wenchao, Trinklein, Nathan D, Buelow, Roland, Buelow, Ben, Fong, Lawrence, Dalvi, Pranjali

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Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies von Harris, Katherine E, Aldred, Shelley Force, Davison, Laura M, Ogana, Heather Anne N, Boudreau, Andrew, Brüggemann, Marianne, Osborn, Michael, Ma, Biao, Buelow, Benjamin, Clarke, Starlynn C, Dang, Kevin H, Iyer, Suhasini, Jorgensen, Brett, Pham, Duy T, Pratap, Payal P, Rangaswamy, Udaya S, Schellenberger, Ute, van Schooten, Wim C, Ugamraj, Harshad S, Vafa, Omid, Buelow, Roland, Trinklein, Nathan D

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Evolutionary Selection on Barrier Activity: Bar1 Is an Aspartyl Protease with Novel Substrate Specificity von Jones, Jr, Stephen K, Clarke, Starlynn C, Craik, Charles S, Bennett, Richard J

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Global landscape of HIV–human protein complexes von Jäger, Stefanie, Cimermancic, Peter, Gulbahce, Natali, Johnson, Jeffrey R., McGovern, Kathryn E., Clarke, Starlynn C., Shales, Michael, Mercenne, Gaelle, Pache, Lars, Li, Kathy, Hernandez, Hilda, Jang, Gwendolyn M., Roth, Shoshannah L., Akiva, Eyal, Marlett, John, Stephens, Melanie, D’Orso, Iván, Fernandes, Jason, Fahey, Marie, Mahon, Cathal, O’Donoghue, Anthony J., Todorovic, Aleksandar, Morris, John H., Maltby, David A., Alber, Tom, Cagney, Gerard, Bushman, Frederic D., Young, John A., Chanda, Sumit K., Sundquist, Wesley I., Kortemme, Tanja, Hernandez, Ryan D., Craik, Charles S., Burlingame, Alma, Sali, Andrej, Frankel, Alan D., Krogan, Nevan J.

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Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies von Trinklein, Nathan D, Pham, Duy, Schellenberger, Ute, Buelow, Ben, Boudreau, Andrew, Choudhry, Priya, Clarke, Starlynn C, Dang, Kevin, Harris, Katherine E, Iyer, Suhasini, Jorgensen, Brett, Pratap, Payal P, Rangaswamy, Udaya S, Ugamraj, Harshad S, Vafa, Omid, Wiita, Arun P, van Schooten, Wim, Buelow, Roland, Force Aldred, Shelley

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Allogeneic chimeric antigen receptor-T cells with CRISPR-disrupted programmed death-1 checkpoint exhibit enhanced functional fitness von Lau, Elaine, Kwong, George, Fowler, Tristan W., Sun, Bee-Chun, Donohoue, Paul D., Davis, Ryan T., Bryan, Mara, McCawley, Shannon, Clarke, Starlynn C., Williams, Carolyn, Banh, Lynda, Irby, Matthew, Edwards, Leslie, Storlie, Meghan, Kohrs, Bryan, Lilley, Graham W.J., Smith, Stephen C., Gradia, Scott, Fuller, Chris K., Skoble, Justin, Garner, Elizabeth, van Overbeek, Megan, Kanner, Steven B.

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Abstract 1554: Uncoupling tumor-cell cytotoxicity from cytokine release with novel T-cell engaging bispecific antibodies von Lorentsen, Kyle, Sankaran, Preethi, Trinklein, Nathan D., Pham, Duy, Schellenberger, Ute, Buelow, Ben, Boudreau, Andrew, Choudhry, Priya, Clarke, Starlynn C., Dang, Kevin, Harris, Katherine E., Iyer, Suhasini, Jorgensen, Brett, Pratap, Payal, Rangaswamy, Udaya S., Ugamraj, Harshad S., Vafa, Omid, Wiita, Arun P., Schooten, Wim van, Buelow, Roland, Aldred, Shelley Force

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TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity von Ugamraj, Harshad S., Dang, Kevin, Ouisse, Laure-Hélène, Buelow, Benjamin, Chini, Eduardo N., Castello, Giulia, Allison, James, Clarke, Starlynn C, Davison, Laura M., Buelow, Roland, Deng, Rong, Iyer, Suhasini, Schellenberger, Ute, Manika, Sankar N., Bijpuria, Shipra, Musnier, Astrid, Poupon, Anne, Cuturi, Maria Cristina, van Schooten, Wim, Dalvi, Pranjali

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Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies von Trinklein, Nathan D., Pham, Duy, Schellenberger, Ute, Buelow, Ben, Boudreau, Andrew, Choudhry, Priya, Clarke, Starlynn C., Dang, Kevin, Harris, Katherine E., Iyer, Suhasini, Jorgensen, Brett, Pratap, Payal P., Rangaswamy, Udaya S., Ugamraj, Harshad S., Vafa, Omid, Wiita, Arun P., van Schooten, Wim, Buelow, Roland, Force Aldred, Shelley

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CD38 ecto-enzyme in immune cells is induced during aging regulating NAD+ and NMN levels von Chini, Claudia C.S., Peclat, Thais R., Warner, Gina M., Kashyap, Sonu, Espindola-Netto, Jair Machado, de Oliveira, Guilherme C., Gomez, Lilian S., Hogan, Kelly A., Tarragó, Mariana G., Puranik, Amrutesh S., Agorrody, Guillermo, Thompson, Katie L., Dang, Kevin, Clarke, Starlynn, Childs, Bennett G., Kanamori, Karina S., Witte, Micaela A., Vidal, Paola, Kirkland, Anna L., De Cecco, Marco, Chellappa, Karthikeyani, McReynolds, Melanie R., Jankowski, Connor, Tchkonia, Tamara, Kirkland, James L., Sedivy, John M., van Deursen, Jan M., Baker, Darren J., van Schooten, Wim, Rabinowitz, Joshua D., Baur, Joseph A., Chini, Eduardo N.

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