ZEB2 Shapes the Epigenetic Landscape of Atherosclerosis von Cheng, Paul, Wirka, Robert C., Shoa Clarke, Lee, Zhao, Quanyi, Kundu, Ramendra, Nguyen, Trieu, Nair, Surag, Sharma, Disha, Kim, Hyun-jung, Shi, Huitong, Assimes, Themistocles, Brian Kim, Juyong, Kundaje, Anshul, Quertermous, Thomas

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ZEB2 Shapes the Epigenetic Landscape of Atherosclerosis von Cheng, Paul, Wirka, Robert C., Clarke, Lee Shoa, Zhao, Quanyi, Kundu, Ramendra, Nguyen, Trieu, Nair, Surag, Sharma, Disha, Kim, Hyun-jung, Shi, Huitong, Assimes, Themistocles, Kim, Juyong Brian, Kundaje, Anshul, Quertermous, Thomas

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Using Mendelian randomisation to identify opportunities for type 2 diabetes prevention by repurposing medications used for lipid management von Khankari, Nikhil K., Keaton, Jacob M., Walker, Venexia M., Lee, Kyung Min, Shuey, Megan M., Clarke, Shoa L., Heberer, Kent R., Miller, Donald R., Reaven, Peter D., Lynch, Julie A., Vujkovic, Marijana, Edwards, Todd L.

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Large-scale genome-wide association study of coronary artery disease in genetically diverse populations von Tcheandjieu, Catherine, Zhu, Xiang, Hilliard, Austin T., Clarke, Shoa L., Napolioni, Valerio, Ma, Shining, Lee, Kyung Min, Fang, Huaying, Chen, Fei, Lu, Yingchang, Tsao, Noah L., Raghavan, Sridharan, Koyama, Satoshi, Gorman, Bryan R., Vujkovic, Marijana, Klarin, Derek, Levin, Michael G., Sinnott-Armstrong, Nasa, Wojcik, Genevieve L., Plomondon, Mary E., Maddox, Thomas M., Waldo, Stephen W., Bick, Alexander G., Pyarajan, Saiju, Huang, Jie, Song, Rebecca, Ho, Yuk-Lam, Buyske, Steven, Kooperberg, Charles, Haessler, Jeffrey, Loos, Ruth J. F., Do, Ron, Verbanck, Marie, Chaudhary, Kumardeep, North, Kari E., Avery, Christy L., Graff, Mariaelisa, Haiman, Christopher A., Le Marchand, Loïc, Wilkens, Lynne R., Bis, Joshua C., Leonard, Hampton, Shen, Botong, Lange, Leslie A., Giri, Ayush, Dikilitas, Ozan, Kullo, Iftikhar J., Stanaway, Ian B., Jarvik, Gail P., Gordon, Adam S., Hebbring, Scott, Namjou, Bahram, Kaufman, Kenneth M., Ito, Kaoru, Ishigaki, Kazuyoshi, Kamatani, Yoichiro, Verma, Shefali S., Ritchie, Marylyn D., Kember, Rachel L., Baras, Aris, Lotta, Luca A., Kathiresan, Sekar, Hauser, Elizabeth R., Miller, Donald R., Lee, Jennifer S., Saleheen, Danish, Reaven, Peter D., Cho, Kelly, Gaziano, J. Michael, Natarajan, Pradeep, Huffman, Jennifer E., Voight, Benjamin F., Rader, Daniel J., Chang, Kyong-Mi, Lynch, Julie A., Damrauer, Scott M., Wilson, Peter W. F., Tang, Hua, Sun, Yan V., Tsao, Philip S., O’Donnell, Christopher J., Assimes, Themistocles L.

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Abstract 14453: Deep Learning Enabled Measurement of Cardiac Sphericity Predicts Disease Risk Among Subjects With Normal Left Ventricular Size and Function von Vukadinovic, Milso, Kwan, Alan C, Salerno, Michael, Lee, Daniel C, Albert, Christine M, Cheng, Susan, Li, Debiao, Ouyang, David, Clarke, Shoa L

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Deep learning-enabled analysis of medical images identifies cardiac sphericity as an early marker of cardiomyopathy and related outcomes von Vukadinovic, Milos, Kwan, Alan C., Yuan, Victoria, Salerno, Michael, Lee, Daniel C., Albert, Christine M., Cheng, Susan, Li, Debiao, Ouyang, David, Clarke, Shoa L.

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A genetically supported drug repurposing pipeline for diabetes treatment using electronic health records von Shuey, Megan M., Lee, Kyung Min, Keaton, Jacob, Khankari, Nikhil K., Breeyear, Joseph H., Walker, Venexia M., Miller, Donald R., Heberer, Kent R., Reaven, Peter D., Clarke, Shoa L., Lee, Jennifer, Lynch, Julie A., Vujkovic, Marijana, Edwards, Todd L.

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Coronary Artery Disease Risk of Familial Hypercholesterolemia Genetic Variants Independent of Clinically Observed Longitudinal Cholesterol Exposure von Clarke, Shoa L., Tcheandjieu, Catherine, Hilliard, Austin T., Lee, Kyung Min, Lynch, Julie, Chang, Kyong-Mi, Miller, Donald, Knowles, Joshua W., O’Donnell, Christopher, Tsao, Philip S., Rader, Daniel J., Wilson, Peter W., Sun, Yan V., Gaziano, J. Michael, Assimes, Themistocles L.

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Abstract 13601: Risk of Coronary Artery Disease Associated With Familial Hypercholesterolemia Genetic Variants is Independent of Historical Low-density Lipoprotein Cholesterol Expo... von Clarke, Shoa L, Tcheandjieu, Catherine, Hilliard, Austin, Lee, Kyung Min, lynch, julie, Chang, Kyong-Mi, Miller, Donald, O'Donnell, Christopher J, Tsao, Philip S, Rader, Daniel J, Wilson, Peter, Sun, Yan V, Gaziano, Michael, Assimes, Themistocles L

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Rare variant contribution to the heritability of coronary artery disease von Rocheleau, Ghislain, Clarke, Shoa L., Auguste, Gaëlle, Hasbani, Natalie R., Morrison, Alanna C., Heath, Adam S., Bielak, Lawrence F., Iyer, Kruthika R., Young, Erica P., Stitziel, Nathan O., Jun, Goo, Laurie, Cecelia, Broome, Jai G., Khan, Alyna T., Arnett, Donna K., Becker, Lewis C., Bis, Joshua C., Boerwinkle, Eric, Bowden, Donald W., Carson, April P., Ellinor, Patrick T., Fornage, Myriam, Franceschini, Nora, Freedman, Barry I., Heard-Costa, Nancy L., Hou, Lifang, Chen, Yii-Der Ida, Kenny, Eimear E., Kooperberg, Charles, Kral, Brian G., Loos, Ruth J. F., Lutz, Sharon M., Manson, JoAnn E., Martin, Lisa W., Mitchell, Braxton D., Nassir, Rami, Palmer, Nicholette D., Post, Wendy S., Preuss, Michael H., Psaty, Bruce M., Raffield, Laura M., Regan, Elizabeth A., Rich, Stephen S., Smith, Jennifer A., Taylor, Kent D., Yanek, Lisa R., Young, Kendra A., Hilliard, Austin T., Tcheandjieu, Catherine, Peyser, Patricia A., Vasan, Ramachandran S., Rotter, Jerome I., Miller, Clint L., Assimes, Themistocles L., de Vries, Paul S., Do, Ron

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A genetically supported drug repurposing pipeline for diabetes treatment using electronic health recordsResearch in context von Megan M. Shuey, Kyung Min Lee, Jacob Keaton, Nikhil K. Khankari, Joseph H. Breeyear, Venexia M. Walker, Donald R. Miller, Kent R. Heberer, Peter D. Reaven, Shoa L. Clarke, Jennifer Lee, Julie A. Lynch, Marijana Vujkovic, Todd L. Edwards

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Coronary Artery Disease Risk of Familial Hypercholesterolemia Genetic Variants Independent of Clinically Observed Longitudinal Cholesterol Exposure von Clarke, Shoa L., Tcheandjieu, Catherine, Hilliard, Austin T., Lee, Min, Lynch, Julie, Chang, Kyong-Mi, Miller, Donald, Knowles, Joshua W., O’Donnell, Christopher, Tsao, Phil, Rader, Daniel J., Wilson, Peter W., Sun, Yan V., Gaziano, Michael, Assimes, Themistocles L.

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