Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders von Cisar, Justin S, Weber, Olivia D, Clapper, Jason R, Blankman, Jacqueline L, Henry, Cassandra L, Simon, Gabriel M, Alexander, Jessica P, Jones, Todd K, Ezekowitz, R. Alan B, O’Neill, Gary P, Grice, Cheryl A

Volltext

Diet-induced mouse model of fatty liver disease and nonalcoholic steatohepatitis reflecting clinical disease progression and methods of assessment von Clapper, Jason R, Hendricks, Michelle D, Gu, Guibao, Wittmer, Carrie, Dolman, Carrie S, Herich, John, Athanacio, Jennifer, Villescaz, Christiane, Ghosh, Soumitra S, Heilig, Joseph S, Lowe, Carolyn, Roth, Jonathan D

Volltext

2-Arachidonoylglycerol Signaling in Forebrain Regulates Systemic Energy Metabolism von Jung, Kwang-Mook, Clapper, Jason R., Fu, Jin, D'Agostino, Giuseppe, Guijarro, Ana, Thongkham, Dean, Avanesian, Agnesa, Astarita, Giuseppe, DiPatrizio, Nicholas V., Frontini, Andrea, Cinti, Saverio, Diano, Sabrina, Piomelli, Daniele

Volltext

Effects of amylin and bupropion/naltrexone on food intake and body weight are interactive in rodent models von Clapper, Jason R., Athanacio, Jennifer, Wittmer, Carrie, Griffin, Pete S., D'Souza, Lawrence, Parkes, David G., Roth, Jonathan D.

Volltext

A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo von Clapper, Jason R., Vacondio, Federica, King, Alvin R., Duranti, Andrea, Tontini, Andrea, Silva, Claudia, Sanchini, Silvano, Tarzia, Giorgio, Mor, Marco, Piomelli, Daniele

Volltext

Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism von Piomelli, Daniele, Clapper, Jason R, Moreno-Sanz, Guillermo, Russo, Roberto, Guijarro, Ana, Vacondio, Federica, Duranti, Andrea, Tontini, Andrea, Sanchini, Silvano, Sciolino, Natale R, Spradley, Jessica M, Hohmann, Andrea G, Calignano, Antonio, Mor, Marco, Tarzia, Giorgio

Volltext

The endocannabinoid system as a target for the treatment of cannabis dependence von Clapper, Jason R., Mangieri, Regina A., Piomelli, Daniele

Volltext

Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators von Clapper, Jason R, Henry, Cassandra L, Niphakis, Micah J, Knize, Anna M, Coppola, Aundrea R, Simon, Gabriel M, Ngo, Nhi, Herbst, Rachel A, Herbst, Dylan M, Reed, Alex W, Cisar, Justin S, Weber, Olivia D, Viader, Andreu, Alexander, Jessica P, Cunningham, Mark L, Jones, Todd K, Fraser, Iain P, Grice, Cheryl A, Ezekowitz, R Alan B, O'Neill, Gary P, Blankman, Jacqueline L

Volltext

Fatty Acid Amide Hydrolase Inhibition Heightens Anandamide Signaling Without Producing Reinforcing Effects in Primates von Justinova, Zuzana, Mangieri, Regina A, Bortolato, Marco, Chefer, Svetlana I, Mukhin, Alexey G, Clapper, Jason R, King, Alvin R, Redhi, Godfrey H, Yasar, Sevil, Piomelli, Daniele, Goldberg, Steven R

Volltext

Synthesis and Quantitative Structure−Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates von Mor, Marco, Lodola, Alessio, Rivara, Silvia, Vacondio, Federica, Duranti, Andrea, Tontini, Andrea, Sanchini, Silvano, Piersanti, Giovanni, Clapper, Jason R, King, Alvin R, Tarzia, Giorgio, Piomelli, Daniele

Volltext

A role for 2-arachidonoylglycerol and endocannabinoid signaling in the locomotor response to novelty induced by olfactory bulbectomy von Eisenstein, Sarah A., Clapper, Jason R., Holmes, Philip V., Piomelli, Daniele, Hohmann, Andrea G.

Volltext

Structure–Property Relationships of a Class of Carbamate‐Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability von Vacondio, Federica, Silva, Claudia, Lodola, Alessio, Fioni, Alessandro, Rivara, Silvia, Duranti, Andrea, Tontini, Andrea, Sanchini, Silvano, Clapper, Jason R., Piomelli, Daniele, Mor, Marco, Tarzia, Giorgio

Volltext

The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues von Clapper, Jason R., Duranti, Andrea, Tontini, Andrea, Mor, Marco, Tarzia, Giorgio, Piomelli, Daniele

Volltext

Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability von Vacondio, Federica, Silva, Claudia, Lodola, Alessio, Carmi, Caterina, Rivara, Silvia, Duranti, Andrea, Tontini, Andrea, Sanchini, Silvano, Clapper, Jason R., Piomelli, Daniele, Tarzia, Giorgio, Mor, Marco

Volltext

Synthesis and Quantitative Structure−Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates von Mor, Marco, Lodola, Alessio, Rivara, Silvia, Vacondio, Federica, Duranti, Andrea, Tontini, Andrea, Sanchini, Silvano, Piersanti, Giovanni, Clapper, Jason R, King, Alvin R, Tarzia, Giorgio, Piomelli, Daniele

Volltext

URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-Arachidonoylglycerol Degradation in Intact Brain Slices von King, Alvin R., Duranti, Andrea, Tontini, Andrea, Rivara, Silvia, Rosengarth, Anja, Clapper, Jason R., Astarita, Giuseppe, Geaga, Jennifer A., Luecke, Hartmut, Mor, Marco, Tarzia, Giorgio, Piomelli, Daniele

Volltext

Identification of a Bioactive Impurity in a Commercial Sample of 6-Methyl-2-p-Tolylaminobenzo[d][1,3]Oxazin-4-One (URB754) von Tarzia, Giorgio, Antonietti, Francesca, Duranti, Andrea, Tontini, Andrea, Mor, Marco, Rivara, Silvia, Traldi, Pietro, Astarita, Giuseppe, King, Alvin, Clapper, Jason R., Piomelli, Daniele

Volltext

Review: The endocannabinoid system as a target for the treatment of cannabis dependence von Clapper, Jason R, Mangieri, Regina A, Piomelli, Daniele

Volltext

Synthesis and QSAR of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates von Mor, Marco, Lodola, Alessio, Rivara, Silvia, Vacondio, Federica, Duranti, Andrea, Tontini, Andrea, Sanchini, Silvano, Piersanti, Giovanni, Clapper, Jason R., King, Alvin R., Tarzia, Giorgio, Piomelli, Daniele

Volltext

Cover Picture: Structure-Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability / A Second Generation... von Vacondio, Federica, Silva, Claudia, Lodola, Alessio, Fioni, Alessandro, Rivara, Silvia, Duranti, Andrea, Tontini, Andrea, Sanchini, Silvano, Clapper, Jason R., Piomelli, Daniele, Mor, Marco, Tarzia, Giorgio, King, Alvin R.

Volltext