A phase 1 'window-of-opportunity' trial testing evofosfamide (TH-302), a tumour-selective hypoxia-activated cytotoxic prodrug, with preoperative chemoradiotherapy in oesophageal ad... von Larue, Ruben T H M, Van De Voorde, Lien, Berbée, Maaike, van Elmpt, Wouter J C, Dubois, Ludwig J, Panth, Kranthi M, Peeters, Sarah G J A, Claessens, Ann, Schreurs, Wendy M J, Nap, Marius, Warmerdam, Fabiënne A R M, Erdkamp, Frans L G, Sosef, Meindert N, Lambin, Philippe

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A Sertoli Cell-Selective Knockout of the Androgen Receptor Causes Spermatogenic Arrest in Meiosis von De Gendt, Karel, Swinnen, Johannes V., Philippa T. K. Saunders, Schoonjans, Luc, Dewerchin, Mieke, Devos, Ann, Tan, Karen, Atanassova, Nina, Claessens, Frank, Lécureuil, Charlotte, Heyns, Walter, Carmeliet, Peter, Guillou, Florian, Sharpe, Richard M., Verhoeven, Guido

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Detection of pan-azole resistant Aspergillus fumigatus in horticulture and a composting facility in Belgium von Hanne, Debergh, Philippe, Castelain, Karine, Goens, Paulien, Lefevere, Jessie, Claessens, De Elien, Vits, Marc, Vissers, Liesbet, Blindeman, Charlotte, Bataille, Claude, Saegerman, Ann, Packeu

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Testosterone boosts physical activity in male mice via dopaminergic pathways von Jardí, Ferran, Laurent, Michaël R., Kim, Nari, Khalil, Rougin, De Bundel, Dimitri, Van Eeckhaut, Ann, Van Helleputte, Lawrence, Deboel, Ludo, Dubois, Vanessa, Schollaert, Dieter, Decallonne, Brigitte, Carmeliet, Geert, Van den Bosch, Ludo, D’Hooge, Rudi, Claessens, Frank, Vanderschueren, Dirk

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Association analyses identify 31 new risk loci for colorectal cancer susceptibility von Law, Philip J., Timofeeva, Maria, Fernandez-Rozadilla, Ceres, Broderick, Peter, Studd, James, Fernandez-Tajes, Juan, Farrington, Susan, Svinti, Victoria, Palles, Claire, Orlando, Giulia, Sud, Amit, Holroyd, Amy, Penegar, Steven, Theodoratou, Evropi, Vaughan-Shaw, Peter, Campbell, Harry, Zgaga, Lina, Hayward, Caroline, Campbell, Archie, Harris, Sarah, Deary, Ian J., Starr, John, Gatcombe, Laura, Pinna, Maria, Briggs, Sarah, Martin, Lynn, Jaeger, Emma, Sharma-Oates, Archana, East, James, Leedham, Simon, Arnold, Roland, Johnstone, Elaine, Wang, Haitao, Kerr, David, Kerr, Rachel, Maughan, Tim, Kaplan, Richard, Al-Tassan, Nada, Palin, Kimmo, Hänninen, Ulrika A., Cajuso, Tatiana, Tanskanen, Tomas, Kondelin, Johanna, Kaasinen, Eevi, Sarin, Antti-Pekka, Eriksson, Johan G., Rissanen, Harri, Knekt, Paul, Pukkala, Eero, Jousilahti, Pekka, Salomaa, Veikko, Ripatti, Samuli, Palotie, Aarno, Renkonen-Sinisalo, Laura, Lepistö, Anna, Böhm, Jan, Mecklin, Jukka-Pekka, Buchanan, Daniel D., Win, Aung-Ko, Hopper, John, Jenkins, Mark E., Lindor, Noralane M., Newcomb, Polly A., Gallinger, Steven, Duggan, David, Casey, Graham, Hoffmann, Per, Nöthen, Markus M., Jöckel, Karl-Heinz, Easton, Douglas F., Pharoah, Paul D. P., Peto, Julian, Canzian, Federico, Swerdlow, Anthony, Eeles, Rosalind A., Kote-Jarai, Zsofia, Muir, Kenneth, Pashayan, Nora, Harkin, Andrea, Allan, Karen, McQueen, John, Paul, James, Iveson, Timothy, Saunders, Mark, Butterbach, Katja, Chang-Claude, Jenny, Hoffmeister, Michael, Brenner, Hermann, Kirac, Iva, Matošević, Petar, Hofer, Philipp, Brezina, Stefanie, Gsur, Andrea, Cheadle, Jeremy P., Aaltonen, Lauri A., Tomlinson, Ian, Houlston, Richard S., Dunlop, Malcolm G.

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The "House of Trust". A framework for quality healthcare and leadership. [version 1; peer review: awaiting peer review] von Vanhaecht, Kris, Lachman, Peter, Van der Auwera, Charlotte, Seys, Deborah, Claessens, Fien, Panella, Massimiliano, De Ridder, Dirk

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Measuring in-hospital quality multidimensionally by integrating patients', kin's and healthcare professionals' perspectives: development and validation of the FlaQuM-Quickscan von Claessens, Fien, Seys, Deborah, Van der Auwera, Charlotte, Jans, Anneke, Castro, Eva Marie, Jacobs, Laura, De Ridder, Dirk, Bruyneel, Luk, Leenaerts, Zita, Van Wilder, Astrid, Brouwers, Jonas, Lachman, Peter, Vanhaecht, Kris

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Large-scale transcriptome-wide association study identifies new prostate cancer risk regions von Mancuso, Nicholas, Gayther, Simon, Gusev, Alexander, Zheng, Wei, Penney, Kathryn L., Kote-Jarai, Zsofia, Eeles, Rosalind, Freedman, Matthew, Haiman, Christopher, Pasaniuc, Bogdan

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Switch to adalimumab in patients with Crohn's disease controlled by maintenance infliximab: prospective randomised SWITCH trial von Van Assche, Gert, Vermeire, Séverine, Ballet, Vera, Gabriels, Frederik, Noman, Maja, D'Haens, Geert, Claessens, Christophe, Humblet, Evelien, Vande Casteele, Niels, Gils, Ann, Rutgeerts, Paul

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A disease‐associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer von Smeets, Elien, Huang, Shengyun, Lee, Xiao Yin, Van Nieuwenhove, Erika, Helsen, Christine, Handle, Florian, Moris, Lisa, El Kharraz, Sarah, Eerlings, Roy, Devlies, Wout, Willemsen, Mathijs, Bücken, Leoni, Prezzemolo, Teresa, Humblet‐Baron, Stephanie, Voet, Arnout, Rochtus, Anne, Van Schepdael, Ann, Zegher, Francis, Claessens, Frank

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Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma von Went, Molly, Sud, Amit, Försti, Asta, Halvarsson, Britt-Marie, Weinhold, Niels, Kimber, Scott, van Duin, Mark, Thorleifsson, Gudmar, Holroyd, Amy, Johnson, David C., Li, Ni, Orlando, Giulia, Law, Philip J., Ali, Mina, Chen, Bowang, Mitchell, Jonathan S., Gudbjartsson, Daniel F., Kuiper, Rowan, Stephens, Owen W., Bertsch, Uta, Broderick, Peter, Campo, Chiara, Bandapalli, Obul R, Einsele, Hermann, Gregory, Walter A., Gullberg, Urban, Hillengass, Jens, Hoffmann, Per, Jackson, Graham H., Jöckel, Karl-Heinz, Johnsson, Ellinor, Kristinsson, Sigurður Y., Mellqvist, Ulf-Henrik, Nahi, Hareth, Easton, Douglas, Pharoah, Paul, Dunning, Alison, Peto, Julian, Canzian, Federico, Swerdlow, Anthony, Eeles, Rosalind A., Kote-Jarai, ZSofia, Muir, Kenneth, Pashayan, Nora, Nickel, Jolanta, Nöthen, Markus M., Rafnar, Thorunn, Ross, Fiona M., da Silva Filho, Miguel Inacio, Thomsen, Hauke, Turesson, Ingemar, Vangsted, Annette, Andersen, Niels Frost, Waage, Anders, Walker, Brian A., Wihlborg, Anna-Karin, Broyl, Annemiek, Davies, Faith E., Thorsteinsdottir, Unnur, Langer, Christian, Hansson, Markus, Goldschmidt, Hartmut, Kaiser, Martin, Sonneveld, Pieter, Stefansson, Kari, Morgan, Gareth J., Hemminki, Kari, Nilsson, Björn, Houlston, Richard S.

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Tumor characteristics and outcome by androgen receptor expression in triple-negative breast cancer patients treated with neo-adjuvant chemotherapy von Jongen, Lynn, Floris, Giuseppe, Wildiers, Hans, Claessens, Frank, Richard, François, Laenen, Annouschka, Desmedt, Christine, Ardui, Jan, Punie, Kevin, Smeets, Ann, Berteloot, Patrick, Vergote, Ignace, Neven, Patrick

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Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis von Yarmolinsky, James, Bouras, Emmanouil, Constantinescu, Andrei, Burrows, Kimberley, Bull, Caroline J., Vincent, Emma E., Martin, Richard M., Dimopoulou, Olympia, Lewis, Sarah J., Moreno, Victor, Vujkovic, Marijana, Chang, Kyong-Mi, Voight, Benjamin F., Tsao, Philip S., Gunter, Marc J., Hampe, Jochen, Pellatt, Andrew J., Pharoah, Paul D. P., Schoen, Robert E., Gallinger, Steven, Jenkins, Mark A., Pai, Rish K., Gill, Dipender, Tsilidis, Kostas K.

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An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk von Wu, Lang, Yang, Yaohua, Guo, Xingyi, Shu, Xiao-Ou, Cai, Qiuyin, Shu, Xiang, Li, Bingshan, Tao, Ran, Wu, Chong, Nikas, Jason B., Sun, Yanfa, Zhu, Jingjing, Roobol, Monique J., Giles, Graham G., Brenner, Hermann, John, Esther M., Clements, Judith, Grindedal, Eli Marie, Park, Jong Y., Stanford, Janet L., Kote-Jarai, Zsofia, Haiman, Christopher A., Eeles, Rosalind A., Zheng, Wei, Long, Jirong

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Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study von Morales Berstein, Fernanda, McCartney, Daniel L, Lu, Ake T, Tsilidis, Konstantinos K, Bouras, Emmanouil, Haycock, Philip, Burrows, Kimberley, Phipps, Amanda I, Buchanan, Daniel D, Cheng, Iona, Martin, Richard M, Davey Smith, George, Relton, Caroline L, Horvath, Steve, Marioni, Riccardo E, Richardson, Tom G, Richmond, Rebecca C

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Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia von Vijayakrishnan, Jayaram, Studd, James, Broderick, Peter, Kinnersley, Ben, Holroyd, Amy, Law, Philip J., Kumar, Rajiv, Allan, James M., Harrison, Christine J., Moorman, Anthony V., Vora, Ajay, Roman, Eve, Rachakonda, Sivaramakrishna, Kinsey, Sally E., Sheridan, Eamonn, Thompson, Pamela D., Irving, Julie A., Koehler, Rolf, Hoffmann, Per, Nöthen, Markus M., Heilmann-Heimbach, Stefanie, Jöckel, Karl-Heinz, Easton, Douglas F., Pharaoh, Paul D. P., Dunning, Alison M., Peto, Julian, Canzian, Frederico, Swerdlow, Anthony, Eeles, Rosalind A., Kote-Jarai, ZSofia, Muir, Kenneth, Pashayan, Nora, Greaves, Mel, Zimmerman, Martin, Bartram, Claus R., Schrappe, Martin, Stanulla, Martin, Hemminki, Kari, Houlston, Richard S.

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Thrombolysis during Resuscitation for Out-of-Hospital Cardiac Arrest von Böttiger, Bernd W, Arntz, Hans-Richard, Chamberlain, Douglas A, Bluhmki, Erich, Belmans, Ann, Danays, Thierry, Carli, Pierre A, Adgey, Jennifer A, Bode, Christoph, Wenzel, Volker

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Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study von Watts, Eleanor L., Gonzales, Tomas I., Strain, Tessa, Saint-Maurice, Pedro F., Bishop, D. Timothy, Chanock, Stephen J., Johansson, Mattias, Keku, Temitope O., Le Marchand, Loic, Moreno, Victor, Newcomb, Polly A., Newton, Christina C., Pai, Rish K., Purdue, Mark P., Ulrich, Cornelia M., Smith-Byrne, Karl, van Guelpen, Bethany, Eeles, Rosalind A., Haiman, Christopher A., Kote-Jarai, Zsofia, Schumacher, Fredrick R., Benlloch, Sara, Olama, Ali Amin Al, Muir, Kenneth R., Berndt, Sonja I., Conti, David V., Wiklund, Fredrik, Chanock, Stephen J., Wang, Ying, Tangen, Catherine M., Batra, Jyotsna, Clements, Judith A., Grönberg, Henrik, Pashayan, Nora, Schleutker, Johanna, Albanes, Demetrius, Weinstein, Stephanie J., Wolk, Alicja, West, Catharine M. L., Mucci, Lorelei A., Cancel-Tassin, Géraldine, Koutros, Stella, Sørensen, Karina Dalsgaard, Grindedal, Eli Marie, Neal, David E., Hamdy, Freddie C., Donovan, Jenny L., Travis, Ruth C., Hamilton, Robert J., Ingles, Sue Ann, Rosenstein, Barry S., Lu, Yong-Jie, Giles, Graham G., MacInnis, Robert J., Kibel, Adam S., Vega, Ana, Kogevinas, Manolis, Penney, Kathryn L., Park, Jong Y., Stanford, Janet L., Cybulski, Cezary, Nordestgaard, Børge G., Nielsen, Sune F., Brenner, Hermann, Maier, Christiane, Kim, Jeri, John, Esther M., Teixeira, Manuel R., Neuhausen, Susan L., De Ruyck, Kim, Razack, Azad, Newcomb, Lisa F., Lessel, Davor, Kaneva, Radka, Usmani, Nawaid, Claessens, Frank, Townsend, Paul A., Castelao, Jose Esteban, Roobol, Monique J., Menegaux, Florence, Khaw, Kay-Tee, Cannon-Albright, Lisa, Pandha, Hardev, Thibodeau, Stephen N., Hunter, David J., Kraft, Peter, Blot, William J., Riboli, Elio, Day, Felix R., Wijndaele, Katrien, Wareham, Nicholas J., Matthews, Charles E., Moore, Steven C., Brage, Soren

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Tumor characteristics and outcome by androgen receptor expression in triple-negative breast cancer patients treated with neo-adjuvant chemotherapy von Jongen, Lynn, Floris, Giuseppe, Wildiers, Hans, Claessens, Frank, Richard, Francois, Laenen, Annouschka, Desmedt, Christine, Ardui, Jan, Punie, Kevin, Smeets, Ann, Berteloot, Patrick, Vergote, Ignace, Neven, Patrick

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Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility von Sud, Amit, Thomsen, Hauke, Law, Philip J., Försti, Asta, Filho, Miguel Inacio da Silva, Holroyd, Amy, Broderick, Peter, Orlando, Giulia, Lenive, Oleg, Wright, Lauren, Cooke, Rosie, Easton, Douglas, Pharoah, Paul, Dunning, Alison, Peto, Julian, Canzian, Federico, Eeles, Rosalind, Kote-Jarai, ZSofia, Muir, Kenneth, Pashayan, Nora, Hoffmann, Per, Nöthen, Markus M., Jöckel, Karl-Heinz, Strandmann, Elke Pogge von, Lightfoot, Tracy, Kane, Eleanor, Roman, Eve, Lake, Annette, Montgomery, Dorothy, Jarrett, Ruth F., Swerdlow, Anthony J., Engert, Andreas, Orr, Nick, Hemminki, Kari, Houlston, Richard S.

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