EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation von Béguelin, Wendy, Popovic, Relja, Teater, Matt, Jiang, Yanwen, Bunting, Karen L., Rosen, Monica, Shen, Hao, Yang, Shao Ning, Wang, Ling, Ezponda, Teresa, Martinez-Garcia, Eva, Zhang, Haikuo, Zheng, Yupeng, Verma, Sharad K., McCabe, Michael T., Ott, Heidi M., Van Aller, Glenn S., Kruger, Ryan G., Liu, Yan, McHugh, Charles F., Scott, David W., Chung, Young Rock, Kelleher, Neil, Shaknovich, Rita, Creasy, Caretha L., Gascoyne, Randy D., Wong, Kwok-Kin, Cerchietti, Leandro, Levine, Ross L., Abdel-Wahab, Omar, Licht, Jonathan D., Elemento, Olivier, Melnick, Ari M.

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ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression von Abdel-Wahab, Omar, Adli, Mazhar, LaFave, Lindsay M., Gao, Jie, Hricik, Todd, Shih, Alan H., Pandey, Suveg, Patel, Jay P., Chung, Young Rock, Koche, Richard, Perna, Fabiana, Zhao, Xinyang, Taylor, Jordan E., Park, Christopher Y., Carroll, Martin, Melnick, Ari, Nimer, Stephen D., Jaffe, Jacob D., Aifantis, Iannis, Bernstein, Bradley E., Levine, Ross L.

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Progression of RAS-Mutant Leukemia during RAF Inhibitor Treatment von Callahan, Margaret K, Rampal, Raajit, Harding, James J, Klimek, Virginia M, Chung, Young Rock, Merghoub, Taha, Wolchok, Jedd D, Solit, David B, Rosen, Neal, Abdel-Wahab, Omar, Levine, Ross L, Chapman, Paul B

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KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function von Gala, Kinisha, Li, Qing, Sinha, Amit, Razavi, Pedram, Dorso, Madeline, Sanchez-Vega, Francisco, Chung, Young Rock, Hendrickson, Ronald, Hsieh, James J., Berger, Michael, Schultz, Nikolaus, Pastore, Alessandro, Abdel-Wahab, Omar, Chandarlapaty, Sarat

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A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease von Mass, Elvira, Jacome-Galarza, Christian E., Blank, Thomas, Lazarov, Tomi, Durham, Benjamin H., Ozkaya, Neval, Pastore, Alessandro, Schwabenland, Marius, Chung, Young Rock, Rosenblum, Marc K., Prinz, Marco, Abdel-Wahab, Omar, Geissmann, Frederic

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Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations von Lee, Stanley Chun-Wei, North, Khrystyna, Kim, Eunhee, Jang, Eunjung, Obeng, Esther, Lu, Sydney X., Liu, Bo, Inoue, Daichi, Yoshimi, Akihide, Ki, Michelle, Yeo, Mirae, Zhang, Xiao Jing, Kim, Min Kyung, Cho, Hana, Chung, Young Rock, Taylor, Justin, Durham, Benjamin H., Kim, Young Joon, Pastore, Alessandro, Monette, Sebastien, Palacino, James, Seiler, Michael, Buonamici, Silvia, Smith, Peter G., Ebert, Benjamin L., Bradley, Robert K., Abdel-Wahab, Omar

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Improved control of SARS-CoV-2 by treatment with a nucleocapsid-specific monoclonal antibody von Dangi, Tanushree, Sanchez, Sarah, Class, Jacob, Richner, Michelle, Visvabharathy, Lavanya, Chung, Young Rock, Bentley, Kirsten, Stanton, Richard J, Koralnik, Igor J, Richner, Justin M, Penaloza-MacMaster, Pablo

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Direct migration of follicular melanocyte stem cells to the epidermis after wounding or UVB irradiation is dependent on Mc1r signaling von Chou, Wei Chin, Takeo, Makoto, Rabbani, Piul, Hu, Hai, Lee, Wendy, Chung, Young Rock, Carucci, John, Overbeek, Paul, Ito, Mayumi

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SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition von Kim, Eunhee, Ilagan, Janine O., Liang, Yang, Daubner, Gerrit M., Lee, Stanley C.-W., Ramakrishnan, Aravind, Li, Yue, Chung, Young Rock, Micol, Jean-Baptiste, Murphy, Michele E., Cho, Hana, Kim, Min-Kyung, Zebari, Ahmad S., Aumann, Shlomzion, Park, Christopher Y., Buonamici, Silvia, Smith, Peter G., Deeg, H. Joachim, Lobry, Camille, Aifantis, Iannis, Modis, Yorgo, Allain, Frederic H.-T., Halene, Stephanie, Bradley, Robert K., Abdel-Wahab, Omar

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Effect of Engine Oil Heater Using EGR on the Fuel Economy and NOx Emission of a Full Size Sedan during Cold Start von Kim, Jung Hyun, Kim, Taewoo, Park, SungJin, Han, JungJae, Jung, Choongsoo, Chung, Young rock, Pae, Sangsoo

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Loss of BAP1 function leads to EZH2-dependent transformation von LaFave, Lindsay M, Béguelin, Wendy, Koche, Richard, Teater, Matt, Spitzer, Barbara, Chramiec, Alan, Papalexi, Efthymia, Keller, Matthew D, Hricik, Todd, Konstantinoff, Katerina, Micol, Jean-Baptiste, Durham, Benjamin, Knutson, Sarah K, Campbell, John E, Blum, Gil, Shi, Xinxu, Doud, Emma H, Krivtsov, Andrei V, Chung, Young Rock, Khodos, Inna, de Stanchina, Elisa, Ouerfelli, Ouathek, Adusumilli, Prasad S, Thomas, Paul M, Kelleher, Neil L, Luo, Minkui, Keilhack, Heike, Abdel-Wahab, Omar, Melnick, Ari, Armstrong, Scott A, Levine, Ross L

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Genomic analysis of hairy cell leukemia identifies novel recurrent genetic alterations von Durham, Benjamin H., Getta, Bartlomiej, Dietrich, Sascha, Taylor, Justin, Won, Helen, Bogenberger, James M., Scott, Sasinya, Kim, Eunhee, Chung, Young Rock, Chung, Stephen S., Hüllein, Jennifer, Walther, Tatjana, Wang, Lu, Lu, Sydney X., Oakes, Christopher C., Tibes, Raoul, Haferlach, Torsten, Taylor, Barry S., Tallman, Martin S., Berger, Michael F., Park, Jae H., Zenz, Thorsten, Abdel-Wahab, Omar

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Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms von Rampal, Raajit, Ahn, Jihae, Abdel-Wahab, Omar, Nahas, Michelle, Wang, Kai, Lipson, Doron, Otto, Geoff A, Yelensky, Roman, Hricik, Todd, McKenney, Anna Sophia, Chiosis, Gabriela, Chung, Young Rock, Pandey, Suveg, van den Brink, Marcel R M, Armstrong, Scott A, Dogan, Ahmet, Intlekofer, Andrew, Manshouri, Taghi, Park, Christopher Y, Verstovsek, Srdan, Rapaport, Franck, Stephens, Philip J, Miller, Vincent A, Levine, Ross L

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Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo von Abdel-Wahab, Omar, Gao, Jie, Adli, Mazhar, Dey, Anwesha, Trimarchi, Thomas, Chung, Young Rock, Kuscu, Cem, Hricik, Todd, Ndiaye-Lobry, Delphine, Lafave, Lindsay M, Koche, Richard, Shih, Alan H, Guryanova, Olga A, Kim, Eunhee, Li, Sheng, Pandey, Suveg, Shin, Joseph Y, Telis, Leon, Liu, Jinfeng, Bhatt, Parva K, Monette, Sebastien, Zhao, Xinyang, Mason, Christopher E, Park, Christopher Y, Bernstein, Bradley E, Aifantis, Iannis, Levine, Ross L

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Adoptive B cell therapy for chronic viral infection von Chung, Young Rock, Dangi, Tanushree, Palacio, Nicole, Sanchez, Sarah, Penaloza-MacMaster, Pablo

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Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML von Yoshimi, Akihide, Balasis, Maria E., Vedder, Alexis, Feldman, Kira, Ma, Yan, Zhang, Hailing, Lee, Stanley Chun-Wei, Letson, Christopher, Niyongere, Sandrine, Lu, Sydney X., Ball, Markus, Taylor, Justin, Zhang, Qing, Zhao, Yulong, Youssef, Salma, Chung, Young Rock, Zhang, Xiao Jing, Durham, Benjamin H., Yang, Wendy, List, Alan F., Loh, Mignon L., Klimek, Virginia, Berger, Michael F., Stieglitz, Elliot, Padron, Eric, Abdel-Wahab, Omar

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TLR4 signaling improves PD-1 blockade therapy during chronic viral infection von Wang, Yidan, Chung, Young Rock, Eitzinger, Simon, Palacio, Nicole, Gregory, Shana, Bhattacharyya, Mitra, Penaloza-MacMaster, Pablo

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ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia von Micol, Jean-Baptiste, Pastore, Alessandro, Inoue, Daichi, Duployez, Nicolas, Kim, Eunhee, Lee, Stanley Chun-Wei, Durham, Benjamin H., Chung, Young Rock, Cho, Hana, Zhang, Xiao Jing, Yoshimi, Akihide, Krivtsov, Andrei, Koche, Richard, Solary, Eric, Sinha, Amit, Preudhomme, Claude, Abdel-Wahab, Omar

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Epigenetic alterations in hematopoietic malignancies von Chung, Young Rock, Schatoff, Emma, Abdel-Wahab, Omar

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An attenuated lymphocytic choriomeningitis virus vector enhances tumor control in mice partly via IFN-I von Chung, Young Rock, Awakoaiye, Bakare, Dangi, Tanushree, Irani, Nahid, Fourati, Slim, Penaloza-MacMaster, Pablo

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