Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP) von Lambert, Lester J, Grotegut, Stefan, Celeridad, Maria, Gosalia, Palak, Backer, Laurent Js De, Bobkov, Andrey A, Salaniwal, Sumeet, Chung, Thomas Dy, Zeng, Fu-Yue, Pass, Ian, Lombroso, Paul J, Cosford, Nicholas Dp, Tautz, Lutz

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New p32/gC1qR Ligands for Targeted Tumor Drug Delivery von Paasonen, Lauri, Sharma, Shweta, Braun, Gary B., Kotamraju, Venkata Ramana, Chung, Thomas D. Y., She, Zhi-Gang, Sugahara, Kazuki N., Yliperttula, Marjo, Wu, Bainan, Pellecchia, Maurizio, Ruoslahti, Erkki, Teesalu, Tambet

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Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase von Stanford, Stephanie M, Aleshin, Alexander E, Zhang, Vida, Ardecky, Robert J, Hedrick, Michael P, Zou, Jiwen, Ganji, Santhi R, Bliss, Matthew R, Yamamoto, Fusayo, Bobkov, Andrey A, Kiselar, Janna, Liu, Yingge, Cadwell, Gregory W, Khare, Shilpi, Yu, Jinghua, Barquilla, Antonio, Chung, Thomas D Y, Mustelin, Tomas, Schenk, Simon, Bankston, Laurie A, Liddington, Robert C, Pinkerton, Anthony B, Bottini, Nunzio

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Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor von Maloney, Patrick R., Khan, Pasha, Hedrick, Michael, Gosalia, Palak, Milewski, Monika, Li, Linda, Roth, Gregory P., Sergienko, Eduard, Suyama, Eigo, Sugarman, Eliot, Nguyen, Kevin, Mehta, Alka, Vasile, Stefan, Su, Ying, Stonich, Derek, Nguyen, Hung, Zeng, Fu-Yue, Novo, Arianna Mangravita, Vicchiarelli, Michael, Diwan, Jena, Chung, Thomas D.Y., Smith, Layton H., Pinkerton, Anthony B.

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays von Zhang, Ji-Hu, Chung, Thomas D.Y., Oldenburg, Kevin R.

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Imidazole-derived agonists for the neurotensin 1 receptor von Hershberger, Paul M, Hedrick, Michael P, Peddibhotla, Satyamaheshwar, Mangravita-Novo, Arianna, Gosalia, Palak, Li, Yujie, Gray, Wilson, Vicchiarelli, Michael, Smith, Layton H, Chung, Thomas D Y, Thomas, James B, Caron, Marc G, Pinkerton, Anthony B, Barak, Lawrence S, Roth, Gregory P

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TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases via cAMP/Gαs signaling von Masyuk, Tatyana V, Masyuk, Anatoliy I, Pisarello, Maria Lorenzo, Howard, Brynn N, Huang, Bing Q, Lee, Pui-Yuen, Fung, Xavier, Sergienko, Eduard, Ardesky, Robert J, Chung, Thomas DY, Pinkerton, Anthony B, LaRusso, Nicholas F

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Assay format as a critical success factor for identification of novel inhibitor chemotypes of tissue-nonspecific alkaline phosphatase from high-throughput screening von Chung, Thomas D Y, Sergienko, Eduard, Millán, José Luis

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High-Throughput Fluorescence Polarization Assay for Chemical Library Screening against Anti-Apoptotic Bcl-2 Family Member Bfl-1 von Zhai, Dayong, Godoi, Paulo, Sergienko, Eduard, Dahl, Russell, Chan, Xochella, Brown, Brock, Rascon, Justin, Hurder, Andrew, Su, Ying, Chung, Thomas D.Y., Jin, Chaofang, Diaz, Paul, Reed, John C.

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DUSP3 Phosphatase Deficiency or Inhibition Limit Platelet Activation and Arterial Thrombosis von Musumeci, Lucia, Kuijpers, Marijke, Gilio, Karen, Hego, Alexandre, Theatre, Emilie, Maurissen, Lisbeth, Vandereyken, Maud, Diogo, Catia, LECUT, Christelle, Guilmain, William, Bobkova, Ekaterina, Eble, Johannes, Dahl, Russell, Drion, Pierre, Rascon, Justin, Mostofi, Yalda, Yuan, Hongbin, Sergienko, Eduard, Chung, Thomas, Thiry, Marc, Senis, Yotis, MOUTSCHEN, Michel, Mustelin, Tomas, Lancellotti, Patrizio, Heemskerk, Johan, Tautz, Lutz, Oury, Cécile, Rahmouni, Souad

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TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases through cyclic adenosine monophosphate/Gαs signaling von Masyuk, Tatyana V., Masyuk, Anatoliy I., Lorenzo Pisarello, Maria, Howard, Brynn N., Huang, Bing Q., Lee, Pui‐Yuen, Fung, Xavier, Sergienko, Eduard, Ardecky, Robert J., Chung, Thomas D.Y., Pinkerton, Anthony B., LaRusso, Nicholas F.

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Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells von Feng, Yongmei, Sessions, E. Hampton, Zhang, Fan, Ban, Fuqiang, Placencio-Hickok, Veronica, Ma, Chen-Ting, Zeng, Fu-Yue, Pass, Ian, Terry, David B., Cadwell, Gregory, Bankston, Laurie A., Liddington, Robert C., Chung, Thomas D.Y., Pinkerton, Anthony B., Sergienko, Eduard, Gleave, Martin, Bhowmick, Neil A., Jackson, Michael R., Cherkasov, Artem, Ronai, Ze'ev A.

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Assay Miniaturization for Ultra-High Throughput Screening of Combinatorial and Discrete Compound Libraries: A 9600-Well (0.2 Microliter) Assay System von Oldenburg, Kevin R., Zhang, Ji-Hu, Chen, Tongming, Maffia, Anthony, Blom, Karl F., Combs, Andrew P., Chung, Thomas D.Y.

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Differences between normal and ras-transformed NIH-3T3 cells in expression of the 170kD and 180kD forms of topoisomerase II von WOESSNER, R. D, CHUNG, T. D. Y, HOFMANN, G. A, MATTERN, M. R, MIRABELLI, C. K, DRAKE, F. H, JOHNSON, R. K

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Identification of Inhibitors of Bacterial Transcription/Translation Machinery Utilizing a Miniaturized 1536-Well Format Screen von Kariv, Ilona, Cao, Hong, Marvil, Phillip D., Bobkova, Ekaterina V., Bukhtiyarov, Yuri E., Yan, Yong P., Patel, Utpal, Coudurier, Louis, Chung, Thomas D.Y., Oldenburg, Kevin R.

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Biological Characterization of Neurokinin Antagonists Discovered Through Screening of a Combinatorial Library von Appell, Kenneth C., Chung, Thomas D.Y., Solly, Kelli J., Chelsky, Daniel

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Biological Screening of a Large Combinatorial Library von Appell, Kenneth C., Chung, Thomas D.Y., Ohlmeyer, Michael J.H., Sigal, Nolan H., Baldwin, John J., Chelsky, Daniel

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Comparison of Automation Equipment in High Throughput Screening von Stevens, Michelle E., Bouchard, Peter J., Kariv, Ilona, Chung, Thomas D.Y., Oldenburg, Kevin R.

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