Asymmetric Synthesis of N‑Boc‑(R)‑Silaproline via Rh-Catalyzed Intramolecular Hydrosilylation of Dehydroalanine and Continuous Flow N‑Alkylation von Chung, John Y. L, Shevlin, Michael, Klapars, Artis, Journet, Michel

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Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods von Klapars, Artis, Chung, John Y. L, Limanto, John, Calabria, Ralph, Campeau, Louis-Charles, Campos, Kevin R, Chen, Wenyong, Dalby, Stephen M, Davis, Tyler A, DiRocco, Daniel A, Hyde, Alan M, Kassim, Amude M, Larsen, Mona Utne, Liu, Guiquan, Maligres, Peter E, Moment, Aaron, Peng, Feng, Ruck, Rebecca T, Shevlin, Michael, Simmons, Bryon L, Song, Zhiguo Jake, Tan, Lushi, Wright, Timothy J, Zultanski, Susan L

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Asymmetric Formal Synthesis of the Long-Acting DPP-4 Inhibitor Omarigliptin von Peng, Feng, Chen, Yonggang, Chen, Cheng-yi, Dormer, Peter G, Kassim, Amude, McLaughlin, Mark, Reamer, Robert A, Sherer, Edward C, Song, Zhiguo J, Tan, Lushi, Tudge, Matthew T, Wan, Baoqiang, Chung, John Y. L

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Asymmetric Synthesis of Cyclic Indole Aminals via 1,3-Stereoinduction von Li, Hongmei, Chen, Cheng-yi, Nguyen, Hoa, Cohen, Ryan, Maligres, Peter E, Yasuda, Nobuyoshi, Mangion, Ian, Zavialov, Ilia, Reibarkh, Mikhail, Chung, John Y. L

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A General Procedure for the Preparation of β-Ketophosphonates von Maloney, Kevin M, Chung, John Y. L

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Evolution of a Manufacturing Route to Omarigliptin, A Long-Acting DPP‑4 Inhibitor for the Treatment of Type 2 Diabetes von Chung, John Y. L, Scott, Jeremy P, Anderson, Camille, Bishop, Brian, Bremeyer, Nadine, Cao, Yang, Chen, Qinghao, Dunn, Robert, Kassim, Amude, Lieberman, David, Moment, Aaron J, Sheen, Faye, Zacuto, Michael

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Development of a Commercial Manufacturing Route to 2‑Fluoroadenine, The Key Unnatural Nucleobase of Islatravir von Hong, Cynthia M, Xu, Yingju, Chung, John Y. L, Schultz, Danielle M, Weisel, Mark, Varsolona, Richard J, Zhong, Yong-Li, Purohit, Akasha K, He, Cyndi Q, Gauthier, Donald R, Humphrey, Guy R, Maloney, Kevin M, Lévesque, François, Wang, Zhixun, Whittaker, Aaron M, Sirota, Eric, McMullen, Jonathan P

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Unusual Pyrimidine Participation: Efficient Stereoselective Synthesis of Potent Dual Orexin Receptor Antagonist MK-6096 von Chung, John Y. L, Zhong, Yong-Li, Maloney, Kevin M, Reamer, Robert A, Moore, Jeffrey C, Strotman, Hallena, Kalinin, Alexei, Feng, Ronnie, Strotman, Neil A, Xiang, Bangping, Yasuda, Nobuyoshi

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Diastereoselective Friedel−Crafts Alkylation of Indoles with Chiral α-Phenyl Benzylic Cations. Asymmetric Synthesis of Anti-1,1,2-Triarylalkanes von Chung, John Y. L, Mancheno, Danny, Dormer, Peter G, Variankaval, Narayan, Ball, Richard G, Tsou, Nancy N

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Synthesis of Antifungal Glucan Synthase Inhibitors from Enfumafungin von Zhong, Yong-Li, Gauthier, Donald R, Shi, Yao-Jun, McLaughlin, Mark, Chung, John Y. L, Dagneau, Philippe, Marcune, Benjamin, Krska, Shane W, Ball, Richard G, Reamer, Robert A, Yasuda, Nobuyoshi

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Synthesis of Vibegron Enabled by a Ketoreductase Rationally Designed for High pH Dynamic Kinetic Reduction von Xu, Feng, Kosjek, Birgit, Cabirol, Fabien L., Chen, Haibin, Desmond, Richard, Park, Jeonghan, Gohel, Anupam P., Collier, Steven J., Smith, Derek J., Liu, Zhuqing, Janey, Jacob M., Chung, John Y. L., Alvizo, Oscar

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Enantioselective Nitrile Anion Cyclization to Substituted Pyrrolidines. A Highly Efficient Synthesis of (3S,4R)-N-tert-Butyl-4-Arylpyrrolidine-3-Carboxylic Acid von Chung, John Y. L, Cvetovich, Raymond, Amato, Joseph, McWilliams, J. Christopher, Reamer, Robert, DiMichele, Lisa

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Diastereoselective FeCl3·6H2O/NaBH4 Reduction of Oxime Ether for the Synthesis of β‑Lactamase Inhibitor Relebactam von Chung, John Y. L, Meng, Dongfang, Shevlin, Michael, Gudipati, Venugopal, Chen, Qinghao, Liu, Yizhou, Lam, Yu-hong, Dumas, Aaron, Scott, Jeremy, Tu, Qiang, Xu, Feng

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Kilogram-Scale Synthesis of 2′‑C‑Methyl-arabino-Uridine from Uridine via Dynamic Selective Dipivaloylation von Chung, John Y. L, Kassim, Amude M, Simmons, Bryon, Davis, Tyler A, Song, Zhiguo J, Limanto, John, Dalby, Stephen M, He, Cyndi Q, Calabria, Ralph, Wright, Timothy J, Campeau, Louis-Charles

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Synthesis of a Naphthyridone p38 MAP Kinase Inhibitor von Chung, John Y. L, Cvetovich, Raymond J, McLaughlin, Mark, Amato, Joseph, Tsay, Fuh-Rong, Jensen, Mark, Weissman, Steve, Zewge, Daniel

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Mild and Practical Method for the α-Arylation of Nitriles with Heteroaryl Halides von Klapars, Artis, Waldman, Jacob H, Campos, Kevin R, Jensen, Mark S, McLaughlin, Mark, Chung, John Y. L, Cvetovich, Raymond J, Chen, Cheng-yi

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Diastereoselective FeCl 3 ·6H 2 O/NaBH 4 Reduction of Oxime Ether for the Synthesis of β-Lactamase Inhibitor Relebactam von Chung, John Y L, Meng, Dongfang, Shevlin, Michael, Gudipati, Venugopal, Chen, Qinghao, Liu, Yizhou, Lam, Yu-Hong, Dumas, Aaron, Scott, Jeremy, Tu, Qiang, Xu, Feng

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Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 3: Development of a One-Pot Formylation–Cyclization Sequence to the Diaminopyrimi... von Basu, Kallol, Lehnherr, Dan, Martin, Gary E, Desmond, Richard A, Lam, Yu-hong, Peng, Feng, Chung, John Y. L, Arvary, Rebecca A, Zompa, Michael A, Zhang, Si-Wei, Liu, Jinchu, Dance, Zachary E. X, Larpent, Patrick, Cohen, Ryan D, Guzman, Francisco J, Rogus, Nicholas J, Di Maso, Michael J, Ren, Hong, Maloney, Kevin M

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Unique Tandem Heck-Lactamization Naphthyridinone Ring Formation between Acrylanilides and Halogenated Pyridines von Cvetovich, Raymond J, Reamer, Robert A, DiMichele, Lisa, Chung, John Y. L, Chilenski, Jennifer R

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Asymmetric Synthesis of cis-2,5-Disubstituted Pyrrolidine, the Core Scaffold of β3‑AR Agonists von Xu, Feng, Chung, John Y. L, Moore, Jeffery C, Liu, Zhuqing, Yoshikawa, Naoki, Hoerrner, R. Scott, Lee, Jaemoon, Royzen, Maksim, Cleator, Ed, Gibson, Andrew G, Dunn, Robert, Maloney, Kevin M, Alam, Mahbub, Goodyear, Adrian, Lynch, Joseph, Yasuda, Nobuyashi, Devine, Paul N

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