Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs von Law, Robert P., Nunes, Joao, Chung, Chun‐wa, Bantscheff, Marcus, Buda, Karol, Dai, Han, Evans, John P., Flinders, Adam, Klimaszewska, Diana, Lewis, Antonia J., Muelbaier, Marcel, Scott‐Stevens, Paul, Stacey, Peter, Tame, Christopher J., Watt, Gillian F., Zinn, Nico, Queisser, Markus A., Harling, John D., Benowitz, Andrew B.

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A Photoaffinity‐Based Fragment‐Screening Platform for Efficient Identification of Protein Ligands von Grant, Emma K., Fallon, David J., Hann, Michael M., Fantom, Ken G. M., Quinn, Chad, Zappacosta, Francesca, Annan, Roland S., Chung, Chun‐wa, Bamborough, Paul, Dixon, David P., Stacey, Peter, House, David, Patel, Vipulkumar K., Tomkinson, Nicholas C. O., Bush, Jacob T.

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Fragment-Based Discovery of Bromodomain Inhibitors Part 1: Inhibitor Binding Modes and Implications for Lead Discovery von Chung, Chun-wa, Dean, Anthony W, Woolven, James M, Bamborough, Paul

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Bromodomain Proteins Contribute to Maintenance of Bloodstream Form Stage Identity in the African Trypanosome von Schulz, Danae, Mugnier, Monica R, Paulsen, Eda-Margaret, Kim, Hee-Sook, Chung, Chun-wa W, Tough, David F, Rioja, Inmaculada, Prinjha, Rab K, Papavasiliou, F Nina, Debler, Erik W

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Discovery of I‑BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition von Theodoulou, Natalie H, Bamborough, Paul, Bannister, Andrew J, Becher, Isabelle, Bit, Rino A, Che, Ka Hing, Chung, Chun-wa, Dittmann, Antje, Drewes, Gerard, Drewry, David H, Gordon, Laurie, Grandi, Paola, Leveridge, Melanie, Lindon, Matthew, Michon, Anne-Marie, Molnar, Judit, Robson, Samuel C, Tomkinson, Nicholas C. O, Kouzarides, Tony, Prinjha, Rab K, Humphreys, Philip G

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Discovery of Epigenetic Regulator I‑BET762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the BET Bromodomains von Mirguet, Olivier, Gosmini, Romain, Toum, Jérôme, Clément, Catherine A, Barnathan, Mélanie, Brusq, Jean-Marie, Mordaunt, Jacqueline E, Grimes, Richard M, Crowe, Miriam, Pineau, Olivier, Ajakane, Myriam, Daugan, Alain, Jeffrey, Phillip, Cutler, Leanne, Haynes, Andrea C, Smithers, Nicholas N, Chung, Chun-wa, Bamborough, Paul, Uings, Iain J, Lewis, Antonia, Witherington, Jason, Parr, Nigel, Prinjha, Rab K, Nicodème, Edwige

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Fragment-Based Discovery of Bromodomain Inhibitors Part 2: Optimization of Phenylisoxazole Sulfonamides von Bamborough, Paul, Diallo, Hawa, Goodacre, Jonathan D, Gordon, Laurie, Lewis, Antonia, Seal, Jonathan T, Wilson, David M, Woodrow, Michael D, Chung, Chun-wa

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A Chemical Probe for the ATAD2 Bromodomain von Bamborough, Paul, Chung, Chun-wa, Demont, Emmanuel H., Furze, Rebecca C., Bannister, Andrew J., Che, Ka Hing, Diallo, Hawa, Douault, Clement, Grandi, Paola, Kouzarides, Tony, Michon, Anne-Marie, Mitchell, Darren J., Prinjha, Rab K., Rau, Christina, Robson, Samuel, Sheppard, Robert J., Upton, Richard, Watson, Robert J.

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The 17th EFMC Short Course on Medicinal Chemistry on Small Molecule Protein Degraders von Ciulli, Alessio, O'Connor, Suzanne, Chung, Chun‐Wa, Hartung, Ingo V., Testa, Andrea, Daniels, Danette L., Heitman, Laura H.

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Structural basis of binding of fluorescent, site-specific dansylated amino acids to human serum albumin von Ryan, Ali J., Ghuman, Jamie, Zunszain, Patricia A., Chung, Chun-wa, Curry, Stephen

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One‐Step Synthesis of Photoaffinity Probes for Live‐Cell MS‐Based Proteomics von Fallon, David J., Lehmann, Stephanie, Chung, Chun‐wa, Phillipou, Alex, Eberl, Christian, Fantom, Ken G. M., Zappacosta, Francesca, Patel, Vipulkumar K., Bantscheff, Marcus, Schofield, Christopher J., Tomkinson, Nicholas C. O., Bush, Jacob T.

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The Discovery of I‑BET726 (GSK1324726A), a Potent Tetrahydroquinoline ApoA1 Up-Regulator and Selective BET Bromodomain Inhibitor von Gosmini, Romain, Nguyen, Van Loc, Toum, Jérôme, Simon, Christophe, Brusq, Jean-Marie G, Krysa, Gael, Mirguet, Olivier, Riou-Eymard, Alizon M, Boursier, Eric V, Trottet, Lionel, Bamborough, Paul, Clark, Hugh, Chung, Chun-wa, Cutler, Leanne, Demont, Emmanuel H, Kaur, Rejbinder, Lewis, Antonia J, Schilling, Mark B, Soden, Peter E, Taylor, Simon, Walker, Ann L, Walker, Matthew D, Prinjha, Rab K, Nicodème, Edwige

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Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases von Tsai, Yi-Chun Isabella, Johansson, Henrik, Dixon, David, Martin, Stephen, Chung, Chun-wa, Clarkson, Jane, House, David, Rittinger, Katrin

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BET inhibition silences expression of MYCN and BCL2 and induces cytotoxicity in neuroblastoma tumor models von Wyce, Anastasia, Ganji, Gopinath, Smitheman, Kimberly N, Chung, Chun-Wa, Korenchuk, Susan, Bai, Yuchen, Barbash, Olena, Le, BaoChau, Craggs, Peter D, McCabe, Michael T, Kennedy-Wilson, Karen M, Sanchez, Lydia V, Gosmini, Romain L, Parr, Nigel, McHugh, Charles F, Dhanak, Dashyant, Prinjha, Rab K, Auger, Kurt R, Tummino, Peter J

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Discovery of a Novel Bromodomain and Extra Terminal Domain (BET) Protein Inhibitor, I-BET282E, Suitable for Clinical Progression von Jones, Katherine L., Beaumont, Dominic M., Bernard, Sharon G., Bit, Rino A., Campbell, Simon P., Chung, Chun-wa, Cutler, Leanne, Demont, Emmanuel H., Dennis, Kate, Gordon, Laurie, Gray, James R., Haase, Michael, Lewis, Antonia J., McCleary, Scott, Mitchell, Darren J., Moore, Susanne M., Parr, Nigel, Robb, Olivia J., Smithers, Nicholas, Soden, Peter E., Suckling, Colin J., Taylor, Simon, Walker, Ann L., Watson, Robert J., Prinjha, Rab K.

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Autism-like syndrome is induced by pharmacological suppression of BET proteins in young mice von Sullivan, Josefa M, Badimon, Ana, Schaefer, Uwe, Ayata, Pinar, Gray, James, Chung, Chun-wa, von Schimmelmann, Melanie, Zhang, Fan, Garton, Neil, Smithers, Nicholas, Lewis, Huw, Tarakhovsky, Alexander, Prinjha, Rab K, Schaefer, Anne

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Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase von Hutchinson, Jonathan P., Rowland, Paul, Taylor, Mark R. D., Christodoulou, Erica M., Haslam, Carl, Hobbs, Clare I., Holmes, Duncan S., Homes, Paul, Liddle, John, Mole, Damian J., Uings, Iain, Walker, Ann L., Webster, Scott P., Mowat, Christopher G., Chung, Chun-wa

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Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1 von Richter, Adrian, Rudolph, Ines, Möllmann, Ute, Voigt, Kerstin, Chung, Chun-wa, Singh, Onkar M. P., Rees, Michael, Mendoza-Losana, Alfonso, Bates, Robert, Ballell, Lluís, Batt, Sarah, Veerapen, Natacha, Fütterer, Klaus, Besra, Gurdyal, Imming, Peter, Argyrou, Argyrides

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Pac13 is a Small, Monomeric Dehydratase that Mediates the Formation of the 3′‐Deoxy Nucleoside of Pacidamycins von Michailidou, Freideriki, Chung, Chun‐wa, Brown, Murray J. B., Bent, Andrew F., Naismith, James H., Leavens, William J., Lynn, Sean M., Sharma, Sunil V., Goss, Rebecca J. M.

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The Commonly Used PI3-Kinase Probe LY294002 Is an Inhibitor of BET Bromodomains von Dittmann, Antje, Werner, Thilo, Chung, Chun-Wa, Savitski, Mikhail M, Fälth Savitski, Maria, Grandi, Paola, Hopf, Carsten, Lindon, Matthew, Neubauer, Gitte, Prinjha, Rabinder K, Bantscheff, Marcus, Drewes, Gerard

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