Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor von Chumanevich, Alexander A, Causey, Corey P, Knuckley, Bryan A, Jones, Justin E, Poudyal, Deepak, Chumanevich, Alena P, Davis, Tia, Matesic, Lydia E, Thompson, Paul R, Hofseth, Lorne J

Volltext

Chronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation von Shaked, Helena, Hofseth, Lorne J, Chumanevich, Alena, Chumanevich, Alexander A, Wang, Jin, Wang, Yinsheng, Taniguchi, Koji, Guma, Monica, Shenouda, Steve, Clevers, Hans, Harris, Curtis C, Karin, Michael

Volltext

The synthetic food dye, Red 40, causes DNA damage, causes colonic inflammation, and impacts the microbiome in mice von Zhang, Qi, Chumanevich, Alexander A., Nguyen, Ivy, Chumanevich, Anastasiya A., Sartawi, Nora, Hogan, Jake, Khazan, Minou, Harris, Quinn, Massey, Bryson, Chatzistamou, Ioulia, Buckhaults, Phillip J., Banister, Carolyn E., Wirth, Michael, Hebert, James R., Murphy, E. Angela, Hofseth, Lorne J.

Volltext

CDK8 selectively promotes the growth of colon cancer metastases in the liver by regulating gene expression of TIMP3 and matrix metalloproteinases von Liang, Jiaxin, Chen, Mengqian, Hughes, Daniel, Chumanevich, Alexander A, Altilia, Serena, Kaza, Vimala, Lim, Chang-Uk, Kiaris, Hippokratis, Mythreye, Karthikeyan, Pena, Maria Marjorette, Broude, Eugenia V, Roninson, Igor B

Volltext

The induction of microRNA-16 in colon cancer cells by protein arginine deiminase inhibition causes a p53-dependent cell cycle arrest von Cui, Xiangli, Witalison, Erin E, Chumanevich, Alena P, Chumanevich, Alexander A, Poudyal, Deepak, Subramanian, Venkataraman, Schetter, Aaron J, Harris, Curtis C, Thompson, Paul R, Hofseth, Lorne J

Volltext

Looking for the best anti-colitis medicine: A comparative analysis of current and prospective compounds von Chumanevich, Anastasiya A, Chaparala, Anusha, Witalison, Erin E, Tashkandi, Hossam, Hofseth, Anne B, Lane, Corey, Pena, Edsel, Liu, Piaomu, Pittman, Doug L, Nagarkatti, Prakash, Nagarkatti, Mitzi, Hofseth, Lorne J, Chumanevich, Alexander A

Volltext

Mast cells and sphingosine‐1‐phosphate underlie prelesional remodeling in a mouse model of eczema von Wedman, P. A., Aladhami, A., Chumanevich, A. P., Fuseler, J. W., Oskeritzian, C. A.

Volltext

Allura Red AC is a xenobiotic. Is it also a carcinogen? von Hofseth, Lorne J, Hebert, James R, Murphy, E Angela, Trauner, Erica, Vikas, Athul, Harris, Quinn, Chumanevich, Alexander A

Volltext

A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics von Zhang, Li, Cheng, Chen, Li, Jing, Wang, Lili, Chumanevich, Alexander A, Porter, Donald C, Mindich, Aleksei, Gorbunova, Svetlana, Roninson, Igor B, Chen, Mengqian, McInnes, Campbell

Volltext

Caught in the Act:  The 1.5 Å Resolution Crystal Structures of the HIV-1 Protease and the I54V Mutant Reveal a Tetrahedral Reaction Intermediate von Kovalevsky, Andrey Y, Chumanevich, Alexander A, Liu, Fengling, Louis, John M, Weber, Irene T

Volltext

Design, Synthesis, Protein−Ligand X-ray Structure, and Biological Evaluation of a Series of Novel Macrocyclic Human Immunodeficiency Virus-1 Protease Inhibitors to Combat Drug Resi... von Ghosh, Arun K, Kulkarni, Sarang, Anderson, David D, Hong, Lin, Baldridge, Abigail, Wang, Yuan-Fang, Chumanevich, Alexander A, Kovalevsky, Andrey Y, Tojo, Yasushi, Amano, Masayuki, Koh, Yasuhiro, Tang, Jordan, Weber, Irene T, Mitsuya, Hiroaki

Volltext

American ginseng suppresses colitis through p53-mediated apoptosis of inflammatory cells von Jin, Yu, Hofseth, Anne B, Cui, Xiangli, Windust, Anthony J, Poudyal, Deepak, Chumanevich, Alex A, Matesic, Lydia E, Singh, Narendra P, Nagarkatti, Mitzi, Nagarkatti, Prakash S, Hofseth, Lorne J

Volltext

Mediator kinase CDK8/CDK19 drives YAP1-dependent BMP4-induced EMT in cancer von Serrao, Anne, Jenkins, Laura M., Chumanevich, Alexander A., Horst, Ben, Liang, Jiaxin, Gatza, Michael L., Lee, Nam Y., Roninson, Igor B., Broude, Eugenia V., Mythreye, Karthikeyan

Volltext

Mediator kinase inhibition reverses castration resistance of advanced prostate cancer von Li, Jing, Hilimire, Thomas A, Yueying, Liu, Wang, Lili, Liang, Jiaxin, Győrffy, Balázs, Sikirzhytski, Vitali, Ji, Hao, Zhang, Li, Cheng, Chen, Ding, Xiaokai, Kerr, Kendall R, Dowling, Charles E, Chumanevich, Alexander A, Mack, Zachary T, Schools, Gary P, Lim, Chang-Uk, Ellis, Leigh, Zi, Xiaolin, Porter, Donald C, Broude, Eugenia V, McInnes, Campbell, Wilding, George, Lilly, Michael B, Roninson, Igor B, Chen, Mengqian

Volltext

Molecules from American Ginseng Suppress Colitis through Nuclear Factor Erythroid-2-Related Factor 2 von Chaparala, Anusha, Tashkandi, Hossam, Chumanevich, Alexander A, Witalison, Erin E, Windust, Anthony, Cui, Taixing, Nagarkatti, Mitzi, Nagarkatti, Prakash, Hofseth, Lorne J

Volltext

Novel complex MAD phasing and RNase H structural insights using selenium oligonucleotides von Abdur, Rob, Gerlits, Oksana O., Gan, Jianhua, Jiang, Jiansheng, Salon, Jozef, Kovalevsky, Andrey Y., Chumanevich, Alexander A., Weber, Irene T., Huang, Zhen

Volltext

Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase von Chumanevich, Alexander A., Poudyal, Deepak, Cui, Xiangli, Davis, Tia, Wood, Patricia A., Smith, Charles D., Hofseth, Lorne J.

Volltext

Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice von Chaparala, Anusha, Poudyal, Deepak, Tashkandi, Hossam, Witalison, Erin E, Chumanevich, Alexander A, Hofseth, Jenna L, Nguyen, Ivy, Hardy, Olivia, Pittman, Douglas L, Wyatt, Michael D, Windust, Anthony, Murphy, Elizabeth A, Nagarkatti, Mitzi, Nagarkatti, Prakash, Hofseth, Lorne J

Volltext

Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties von Chumanevich, Alexander A, Witalison, Erin E, Chaparala, Anusha, Chumanevich, Anastasiya, Nagarkatti, Prakash, Nagarkatti, Mitzi, Hofseth, Lorne J

Volltext

Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer von McDermott, Martina S J, Chumanevich, Alexander A, Lim, Chang-Uk, Liang, Jiaxin, Chen, Mengqian, Altilia, Serena, Oliver, David, Rae, James M, Shtutman, Michael, Kiaris, Hippokratis, Győrffy, Balázs, Roninson, Igor B, Broude, Eugenia V

Volltext