DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia von Johnson, Darren C., Taabazuing, Cornelius Y., Okondo, Marian C., Chui, Ashley J., Rao, Sahana D., Brown, Fiona C., Reed, Casie, Peguero, Elizabeth, de Stanchina, Elisa, Kentsis, Alex, Bachovchin, Daniel A.

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Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome von Okondo, Marian C., Rao, Sahana D., Taabazuing, Cornelius Y., Chui, Ashley J., Poplawski, Sarah E., Johnson, Darren C., Bachovchin, Daniel A.

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N-terminal degradation activates the NLRP1B inflammasome von Chui, Ashley J, Okondo, Marian C, Rao, Sahana D, Gai, Kuo, Griswold, Andrew R, Johnson, Darren C, Ball, Daniel P, Taabazuing, Cornelius Y, Orth, Elizabeth L, Vittimberga, Brooke A, Bachovchin, Daniel A

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DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis von Okondo, Marian C, Johnson, Darren C, Sridharan, Ramya, Go, Eun Bin, Chui, Ashley J, Wang, Mitchell S, Poplawski, Sarah E, Wu, Wengen, Liu, Yuxin, Lai, Jack H, Sanford, David G, Arciprete, Michael O, Golub, Todd R, Bachovchin, William W, Bachovchin, Daniel A

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DPP8/9 inhibitors are universal activators of functional NLRP1 alleles von Gai, Kuo, Okondo, Marian C., Rao, Sahana D., Chui, Ashley J., Ball, Daniel P., Johnson, Darren C., Bachovchin, Daniel A.

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DPP9’s Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation von Griswold, Andrew R, Ball, Daniel P, Bhattacharjee, Abir, Chui, Ashley J, Rao, Sahana D, Taabazuing, Cornelius Y, Bachovchin, Daniel A

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M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome von Rao, Sahana D., Chen, Qifeng, Wang, Qinghui, Orth-He, Elizabeth L., Saoi, Michelle, Griswold, Andrew R., Bhattacharjee, Abir, Ball, Daniel P., Huang, Hsin-Che, Chui, Ashley J., Covelli, Dominic J., You, Shaochen, Cross, Justin R., Bachovchin, Daniel A.

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A ubiquitin-independent proteasome pathway controls activation of the CARD8 inflammasome von Hsiao, Jeffrey C., Neugroschl, Atara R., Chui, Ashley J., Taabazuing, Cornelius Y., Griswold, Andrew R., Wang, Qinghui, Huang, Hsin-Che, Orth-He, Elizabeth L., Ball, Daniel P., Hiotis, Giorgos, Bachovchin, Daniel A.

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The hydrophobicity of the CARD8 N-terminus tunes inflammasome activation von Tsamouri, Lydia P., Hsiao, Jeffrey C., Wang, Qinghui, Geeson, Michael B., Huang, Hsin-Che, Nambiar, Deepika R., Zou, Mengyang, Ball, Daniel P., Chui, Ashley J., Bachovchin, Daniel A.

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Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation von Orth-He, Elizabeth L., Huang, Hsin-Che, Rao, Sahana D., Wang, Qinghui, Chen, Qifeng, O’Mara, Claire M., Chui, Ashley J., Saoi, Michelle, Griswold, Andrew R., Bhattacharjee, Abir, Ball, Daniel P., Cross, Justin R., Bachovchin, Daniel A.

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Activation of the CARD8 Inflammasome Requires a Disordered Region von Chui, Ashley J., Griswold, Andrew R., Taabazuing, Cornelius Y., Orth, Elizabeth L., Gai, Kuo, Rao, Sahana D., Ball, Daniel P., Hsiao, Jeffrey C., Bachovchin, Daniel A.

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Multiple Structural States Exist Throughout the Helical Nucleation Sequence of the Intrinsically Disordered Protein Stathmin, As Reported by Electron Paramagnetic Resonance Spectro... von Chui, Ashley J, López, Carlos J, Brooks, Evan K, Chua, Katherina C, Doupey, Tonia G, Foltz, Gretchen N, Kamel, Joseph G, Larrosa, Estefania, Sadiki, Amissi, Bridges, Michael D

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Stathmin Exists as an Oligomer in Solution, as Evidenced by Static Light-Scattering, Native Gel Electrophoresis, and EPR Spectroscopy von Chui, Ashley J., Chua, Katherina C., Bridges, Michael D.

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DPP8/9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia von Johnson, Darren C., Taabazuing, Cornelius Y., Okondo, Marian C., Chui, Ashley J., Rao, Sahana D., Brown, Fiona C., Reed, Casie, Peguero, Elizabeth, de Stanchina, Elisa, Kentsis, Alex, Bachovchin, Daniel A.

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DPP8/9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis von Okondo, Marian C., Johnson, Darren C., Sridharan, Ramya, Go, Eun Bin, Chui, Ashley J., Wang, Mitchell S., Poplawski, Sarah E., Wu, Wengen, Liu, Yuxin, Lai, Jack H., Sanford, David G., Arciprete, Michael O., Golub, Todd R., Bachovchin, William W., Bachovchin, Daniel A.

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Identifying and characterizing hepatitis C virus hotspots in Massachusetts: a spatial epidemiological approach von Stopka, Thomas J, Goulart, Michael A, Meyers, David J, Hutcheson, Marga, Barton, Kerri, Onofrey, Shauna, Church, Daniel, Donahue, Ashley, Chui, Kenneth K H

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The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation von Smith, Brenden W., Rozelle, Sarah S., Leung, Amy, Ubellacker, Jessalyn, Parks, Ashley, Nah, Shirley K., French, Deborah, Gadue, Paul, Monti, Stefano, Chui, David H.K., Steinberg, Martin H., Frelinger, Andrew L., Michelson, Alan D., Theberge, Roger, McComb, Mark E., Costello, Catherine E., Kotton, Darrell N., Mostoslavsky, Gustavo, Sherr, David H., Murphy, George J.

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Brain delivery of supplemental docosahexaenoic acid (DHA): A randomized placebo-controlled clinical trial von Arellanes, Isabella C., Choe, Nicholas, Solomon, Victoria, He, Xulei, Kavin, Brian, Martinez, Ashley E., Kono, Naoko, Buennagel, David P., Hazra, Nalini, Kim, Giselle, D'Orazio, Lina M., McCleary, Carol, Sagare, Abhay, Zlokovic, Berislav V., Hodis, Howard N., Mack, Wendy J., Chui, Helena C., Harrington, Michael G., Braskie, Meredith N., Schneider, Lon S., Yassine, Hussein N.

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Correlation between Phenotypic and In Silico Detection of Antimicrobial Resistance in Salmonella enterica in Canada Using Staramr von Bharat, Amrita, Petkau, Aaron, Avery, Brent P, Chen, Jessica C, Folster, Jason P, Carson, Carolee A, Kearney, Ashley, Nadon, Celine, Mabon, Philip, Thiessen, Jeffrey, Alexander, David C, Allen, Vanessa, El Bailey, Sameh, Bekal, Sadjia, German, Greg J, Haldane, David, Hoang, Linda, Chui, Linda, Minion, Jessica, Zahariadis, George, Domselaar, Gary Van, Reid-Smith, Richard J, Mulvey, Michael R

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Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5′ olfactory receptor gene cluster von Solovieff, Nadia, Milton, Jacqueline N., Hartley, Stephen W., Sherva, Richard, Sebastiani, Paola, Dworkis, Daniel A., Klings, Elizabeth S., Farrer, Lindsay A., Garrett, Melanie E., Ashley-Koch, Allison, Telen, Marilyn J., Fucharoen, Supan, Ha, Shau Yin, Li, Chi-Kong, Chui, David H.K., Baldwin, Clinton T., Steinberg, Martin H.

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