Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain von Gagnon, Etienne, Schubert, David A, Gordo, Susana, Chu, H Hamlet, Wucherpfennig, Kai W

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Continuous Effector CD8+ T Cell Production in a Controlled Persistent Infection Is Sustained by a Proliferative Intermediate Population von Chu, H. Hamlet, Chan, Shiao-Wei, Gosling, John Paul, Blanchard, Nicolas, Tsitsiklis, Alexandra, Lythe, Grant, Shastri, Nilabh, Molina-París, Carmen, Robey, Ellen A.

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Quantitative impact of thymic selection on Foxp3+ and Foxp3– subsets of self-peptide/MHC class II-specific CD4+ T cells von Moon, James J, Dash, Pradyot, Oguin, Thomas H. III, McClaren, Jennifer L, Chu, H. Hamlet, Thomas, Paul G, Jenkins, Marc K

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Location of the CD8 T cell epitope within the antigenic precursor determines immunogenicity and protection against the Toxoplasma gondii parasite von Feliu, Virginie, Vasseur, Virginie, Grover, Harshita S, Chu, H Hamlet, Brown, Mark J, Wang, Jeremy, Boyle, Jon P, Robey, Ellen A, Shastri, Nilabh, Blanchard, Nicolas

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Peptide Centric Vβ Specific Germline Contacts Shape a Specialist T Cell Response von Wang, Yang, Tsitsiklis, Alexandra, Devoe, Stephanie, Gao, Wei, Chu, H Hamlet, Zhang, Yan, Li, Wei, Wong, Wing Ki, Deane, Charlotte M, Neau, David, Slansky, Jill E, Thomas, Paul G, Robey, Ellen A, Dai, Shaodong

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The Transcription Factors Thpok and LRF Are Necessary and Partly Redundant for T Helper Cell Differentiation von Carpenter, Andrea C., Grainger, John R., Xiong, Yumei, Kanno, Yuka, Chu, H. Hamlet, Wang, Lie, Naik, Shruti, dos Santos, Liliane, Wei, Lai, Jenkins, Marc K., O’Shea, John J., Belkaid, Yasmine, Bosselut, Rémy

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Impact of Regulated Secretion on Antiparasitic CD8 T Cell Responses von Grover, Harshita Satija, Chu, H. Hamlet, Kelly, Felice D., Yang, Soo Jung, Reese, Michael L., Blanchard, Nicolas, Gonzalez, Federico, Chan, Shiao Wei, Boothroyd, John C., Shastri, Nilabh, Robey, Ellen A.

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847 Pharmacokinetics and pharmacodynamics of GS-3583 in cynomolgus monkeys von Kuhne, Michelle, Chu, Hamlet, Clarke, Christopher, Carr, Brian, Baca, Manuel, Hung, Magdeleine, Nagel, Mark, Ambrogelly, Alexandre, Rajakumaraswamy, Nishanathan

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846 Pre-clinical validation of a FLT3L-fusion protein for dendritic cell expansion and anti-tumor efficacy von Kuhne, Michelle, Chu, Hamlet, Ng, Sarah, Clarke, Christopher, Carr, Brian, Baca, Manuel, Hung, Magdeleine, Nagel, Mark, Ambrogelly, Alexandre, Wilson, Nicholas

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Positive selection optimizes the number and function of MHCII-restricted CD4⁺ T cell clones in the naive polyclonal repertoire von Chu, H. Hamlet, Moon, James J, Takada, Kensuke, Pepper, Marion, Molitor, Jerry A, Schacker, Timothy W, Hogquist, Kristin A, Jameson, Stephen C, Jenkins, Marc K

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Naive CD4 + T Cell Frequency Varies for Different Epitopes and Predicts Repertoire Diversity and Response Magnitude von Moon, James J., Chu, H. Hamlet, Pepper, Marion, McSorley, Stephen J., Jameson, Stephen C., Kedl, Ross M., Jenkins, Marc K.

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On the composition of the preimmune repertoire of T cells specific for Peptide-major histocompatibility complex ligands von Jenkins, Marc K, Chu, H Hamlet, McLachlan, James B, Moon, James J

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Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire von Burchill, Matthew A., Yang, Jianying, Vang, Kieng B., Moon, James J., Chu, H. Hamlet, Lio, Chan-Wang J., Vegoe, Amanda L., Hsieh, Chyi-Song, Jenkins, Marc K., Farrar, Michael A.

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Tracking epitope-specific T cells von Jenkins, Marc K, Moon, James J, Chu, H Hamlet, Hataye, Jason, Pagán, Antonio J, Pepper, Marion, McLachlan, James B, Zell, Traci

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Dendritic Cells Amplify T Cell-Mediated Immune Responses in the Central Nervous System von Karman, Jozsef, Chu, Hamlet H, Co, Dominic O, Seroogy, Christine M, Sandor, Matyas, Fabry, Zsuzsanna

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Antigen dependent checkpoints for generating a persisting effector CD8 T cell population during chronic parasite infection (MPF6P.737) von Chu, Hamlet, Robey, Ellen

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The same well-characterized T cell epitope SIINFEKL expressed in the context of a cytoplasmic or secreted protein in BCG induces different CD8+ T cell responses von Hulseberg, Paul D, Zozulya, Alla, Chu, Hamlet H, Triccas, James A, Fabry, Zsuzsanna, Sandor, Matyas

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Negative selection and peptide chemistry determine the size of naive foreign peptide-MHC class II-specific CD4+ T cell populations von Chu, H Hamlet, Moon, James J, Kruse, Andrew C, Pepper, Marion, Jenkins, Marc K

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CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs von Pagán, Antonio J, Pepper, Marion, Chu, H Hamlet, Green, Jonathan M, Jenkins, Marc K

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Response Multilayered Control of T Cell Receptor Phosphorylation von Gagnon, Etienne, Xu, Chenqi, Yang, Wei, Chu, H. Hamlet, Call, Matthew E., Chou, James J., Wucherpfennig, Kai W.

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