Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels von Tin, Adrienne, Li, Yong, Brody, Jennifer A., Nutile, Teresa, Chu, Audrey Y., Huffman, Jennifer E., Yang, Qiong, Chen, Ming-Huei, Robinson-Cohen, Cassianne, Macé, Aurélien, Liu, Jun, Demirkan, Ayşe, Sorice, Rossella, Sedaghat, Sanaz, Swen, Melody, Yu, Bing, Ghasemi, Sahar, Teumer, Alexanda, Vollenweider, Peter, Ciullo, Marina, Li, Meng, Uitterlinden, André G., Kraaij, Robert, Amin, Najaf, van Rooij, Jeroen, Kutalik, Zoltán, Dehghan, Abbas, McKnight, Barbara, van Duijn, Cornelia M., Morrison, Alanna, Psaty, Bruce M., Boerwinkle, Eric, Fox, Caroline S., Woodward, Owen M., Köttgen, Anna

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Gene x physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry von Ahmad, Shafqat, Rukh, Gull, Varga, Tibor V, Ali, Ashfaq, Kurbasic, Azra, Shungin, Dmitry, Ericson, Ulrika, Koivula, Robert W, Chu, Audrey Y, Rose, Lynda M, Ganna, Andrea, Qi, Qibin, Stancakova, Alena, Sandholt, Camilla H, Elks, Cathy E, Curhan, Gary, Jensen, Majken K, Tamimi, Rulla M, Allin, Kristine H, Jorgensen, Torben, Brage, Soren, Langenberg, Claudia, Aadahl, Mette, Grarup, Niels, Linneberg, Allan, Pare, Guillaume, Magnusson, Patrik KE, Pedersen, Nancy L, Boehnke, Michael, Hamsten, Anders, Mohlke, Karen L, Pasquale, Louis T, Pedersen, Oluf, Scott, Robert A, Ridker, Paul M, Ingelsson, Erik, Laakso, Markku, Hansen, Torben, Qi, Lu, Wareham, Nicholas J, Chasman, Daniel I, Hallmans, Göran, Hu, Frank B, Renström, Frida, Orho-Melander, Marju, Franks, Paul W.

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Utility of D2-40, a novel mesothelial marker, in the diagnosis of malignant mesothelioma von Chu, Albert Y, Litzky, Leslie A, Pasha, Theresa L, Acs, Geza, Zhang, Paul J

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The Type 2 Diabetes Knowledge Portal: an open access genetic resource dedicated to type 2 diabetes and related traits von Costanzo, MC, Von Grotthuss, M, Massung, J, Jang, D, Caulkins, L, Koesterer, R, Gilbert, C, Welch, RP, Kudtarkar, P, Hoang, Q, Boughton, AP, Singh, P, Sun, Y, Duby, M, Moriondo, A, Nguyen, T, Smadbeck, P, Alexander, BR, Brandes, M, Carmichael, M, Dornbos, P, Green, T, Huellas-Bruskiewicz, KC, Ji, Y, Kluge, A, McMahon, AC, Mercader, JM, Ruebenacker, O, Sengupta, S, Spalding, D, Taliun, D, AMP-T2D Consortium, Smith, P, Thomas, MK, Akolkar, B, Brosnan, MJ, Cherkas, A, Chu, AY, Fauman, EB, Fox, CS, Kamphaus, TN, Miller, MR, Nguyen, L, Parsa, A, Reilly, DF, Ruetten, H, Wholley, D, Zaghloul, NA, Abecasis, GR, Altshuler, D, Keane, TM, McCarthy, MI, Gaulton, KJ, Florez, JC, Boehnke, M, Burtt, NP, Flannick, J

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An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis von Liu, J, Carnero-Montoro, E, Van Dongen, J, Lent, S, Nedeljkovic, I, Ligthart, S, Tsai, P-C, Martin, TC, Mandaviya, PR, Jansen, R, Peters, MJ, Duijts, L, Jaddoe, VWV, Tiemeier, H, Felix, JF, Willemsen, G, De Geus, EJC, Chu, AY, Levy, D, Hwang, S-J, Bressler, J, Gondalia, R, Salfati, EL, Herder, C, Hidalgo, BA, Tanaka, T, Moore, AZ, Lemaitre, RN, Jhun, MA, Smith, JA, Sotoodehnia, N, Bandinelli, S, Ferrucci, L, Arnett, DK, Grallert, H, Assimes, TL, Hou, L, Baccarelli, A, Whitsel, EA, Van Dijk, KW, Amin, N, Uitterlinden, AG, Sijbrands, EJG, Franco, OH, Dehghan, A, Spector, TD, Dupuis, J, Hivert, M-F, Rotter, J, Meigs, JB, Pankow, JS, Van Meurs, JBJ, Isaacs, A, Boomsma, D, Bell, JT, Demirkan, A, Van Duijn, CM

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Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels von Tin, A, Li, Y, Brody, JA, Nutile, T, Chu, AY, Huffman, JE, Yang, Q, Chen, M-H, Robinson-Cohen, C, Macé, A, Liu, J, Demirkan, A, Sorice, R, Sedaghat, S, Swen, M, Yu, B, Ghasemi, S, Teumer, A, Vollenweider, P, Ciullo, M, Li, M, Uitterlinden, AG, Kraaij, R, Amin, N, Van Rooij, J, Kutalik, Z, Dehghan, A, McKnight, B, Van Duijn, CM, Morrison, A, Psaty, BM, Boerwinkle, E, Fox, CS, Woodward, OM, Köttgen, A

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Associations of mitochondrial and nuclear mitochondrial variants and genes with seven metabolic traits von Kraja, AT, Liu, C, Graff, M, Gu, C, Arking, DE, Chasman, D, Young, K, Weiss, S, Luan, J, Giulianini, F, Li-Gao, R, Lin, SJ, Wang, L, Richardson, TG, Ghanbari, M, Wojczynski, MK, Armasu, SM, Barve, RA, Bielinski, SJ, Bowden, DW, Broeckel, U, Chu, AY, Corley, J, Cox, SR, Uitterlinden, AG, Cropp, CD, Daw, EW, Van Heemst, D, Gao, H, Tzoulaki, I, Ahluwalia, TS, De Mutsert, R, Emery, LS, Perry, JA, Fu, M, Forouhi, NG, Gu, Z, Hai, Y, Harris, SE, Hemani, G, Hunt, SC, Irvin, MR, Justice, AE, Larson, NB, Love-Gregory, LD, Lee, JH, Nauck, M, Noordam, R, Patki, A, Pattie, A, Petersmann, A, Qi, Q, Rohde, R, Sandow, K, Sofer, T, Starr, JM, Taylor, AM, Timpson, NJ, De Haan, HG, Wang, Y, Williams, C, Wu, H, Witte, DR, Vestergaard, H, Turner, ST, Torp-Pedersen, C, Sheu, WH-H, Rosendaal, FR, Franco, OH, Ridker, PM, Perls, TT, Pedersen, O, Nohr, EA, Linneberg, A, Kilpelainen, TO, Kardia, SLR, Jorgensen, T, Sorensen, TIA, Goodarzi, MO, Christensen, C, Chen, Y-DI, Chakravarti, A, Brandslund, I, Bonnelykke, K, Rodriguez, S, Davies, G, Horta, BL, Rao, DC, Davila-Roman, VG, Hudson, G, Hayward, C, Vaidya, D, Tiwari, HK, Levy, D, Malik, AN, Becker, DM, De Andrade, M, Meigs, JB, Rotter, J, North, KE

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DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases von Ligthart, S, Marzi, C, Aslibekyan, S, Mendelson, MM, Conneely, KN, Tanaka, T, Colicino, E, Waite, LL, Joehanes, R, Guan, W, Brody, JA, Elks, C, Marioni, R, Jhun, MA, Agha, G, Bressler, J, Ward-Caviness, CK, Chen, BH, Huan, T, Bakulski, K, Salfati, EL, Wahl, S, Schramm, K, Sha, J, Hernandez, DG, Just, AC, Smith, JA, Sotoodehnia, N, Pilling, LC, Pankow, JS, Tsao, PS, Liu, C, Zhao, W, Guarrera, S, Michopoulos, VJ, Smith, AK, Peters, MJ, Melzer, D, Vokonas, P, Fornage, M, Prokisch, H, Bis, JC, Chu, AY, Herder, C, Grallert, H, Yao, C, Shah, S, McRae, AF, Lin, H, Horvath, S, Fallin, D, Hofman, A, Wareham, NJ, Wiggins, KL, Feinberg, AP, Starr, JM, Visscher, PM, Murabito, JM, Kardia, SLR, Absher, DM, Binder, EB, Singleton, AB, Bandinelli, S, Peters, A, Waldenberger, M, Matullo, G, Schwartz, JD, Demerath, EW, Uitterlinden, AG, Van Meurs, JBJ, Franco, OH, Chen, Y-DI, Levy, D, Turner, ST, Deary, IJ, Ressler, KJ, Dupuis, J, Ferrucci, L, Ong, KK, Assimes, TL, Boerwinkle, E, Koenig, W, Arnett, DK, Baccarelli, AA, Benjamin, EJ, Dehghan, A

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No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels von SCOTT, Robert A, CHU, Audrey Y, GLAZER, Nicole L, JACKSON, Anne U, KUTALIK, Zoltan, LAGOU, Vasiliki, MAREK, Diana, RASMUSSEN-TORVIK, Laura J, STRINGHAM, Heather M, TANAKA, Toshiko, AADAHL, Mette, ARKING, Dan E, GRARUP, Niels, BERGMANN, Sven, BOERWINKLE, Eric, BONNYCASTLE, Lori L, BORNSTEIN, Stefan R, BRUNNER, Eric, BUMPSTEAD, Suzannah J, BRAGE, Soren, CARLSON, Olga D, HAN CHEN, CHEN, Yii-Der Ida, MANNING, Alisa K, CHINES, Peter S, COLLINS, Francis S, COUPER, David J, DENNISON, Elaine M, DOWLING, Nicole F, EGAN, Josephine S, EKELUND, Ulf, ERDOS, Michael R, FOROUHI, Nita G, FOX, Caroline S, HIVERT, Marie-France, GOODARZI, Mark O, GRÄSSLER, Jiirgen, GUSTAFSSON, Stefan, HALLMANS, Göran, HANSEN, Torben, HINGORANI, Aroon, HOLLOWAY, John W, HU, Frank B, ISOMAA, Bo, JAMESON, Karen A, SHUNGIN, Dmitry, JOHANSSON, Ingegerd, JONSSON, Anna, JØRGENSEN, Torben, KIVIMAKI, Mika, KOVACS, Peter, KUMARI, Meena, KUUSISTO, Johanna, LAAKSO, Markku, LECOEUR, Cecile, LEVY-MARCHAL, Claire, TÖNJES, Anke, YESUPRIYA, Ajay, BARNES, Daniel, BOUATIA-NAJI, Nabila

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A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease von Scott, RA, Li, L, Chu, AY, Surendran, P, Stancakova, A, Yaghootkar, H, Luan, J, Zhao, JH, Wessel, J, Wang, S, Maruthur, N, Michailidou, K, Pirie, A, Van der Lee, SJ, Gillson, C, Al Olama, AA, Amouyel, P, Arveiler, D, Aviles-Olmos, I, Barricarte, A, Barroso, I, Garcia, SB, Bis, JC, Boehnke, M, Boeing, H, Boerwinkle, E, Borecki, IB, Bork-Jensen, J, Bowden, S, Caldas, C, Caslake, M, Cupples, LA, Cruchaga, C, Czajkowski, J, Dunn, JA, Earl, HM, Ehret, GB, Ferrieres, J, Foltynie, T, Ford, I, Gonzalez, C, Grioni, S, Jansson, J-H, Jorgensen, ME, Jukema, JW, Kee, F, Kerrison, ND, Key, TJ, Kontto, J, Kraja, AT, Kuusisto, J, Linneberg, A, Liu, C, Marenne, G, Mohlke, KL, Morris, AP, Munroe, PB, Navarro, C, Nielsen, SF, Nordestgaard, BG, Packard, CJ, Panico, S, Peloso, GM, Peters, A, Quiros, JR, Sacerdote, C, Sattar, N, Sharp, SJ, Sims, R, Smith, JA, Thompson, DJ, Trompet, S, Tumino, R, Van der Schouw, YT, Virtamo, J, Walker, M, Walter, K, Abraham, JE, Amundadottir, LT, Aponte, JL, Butterworth, A, Dupuis, J, Easton, DF, Eeles, RA, Erdmann, J, Franks, PW, Hansen, T, Kooner, J, Langenberg, C, Pankow, JS, Pedersen, O, Riboli, E, Saleheen, D, Schunkert, H, Vollenweider, P, O'Rahilly, S, Deloukas, P, Meigs, JB, Wareham, NJ, Waterworth, DM

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Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins von Postmus, I, Trompet, S, Deshmukh, HA, Barnes, MR, Li, X, Warren, HR, Chasman, DI, Zhou, K, Arsenault, BJ, Donnelly, LA, Wiggins, KL, Krauss, RM, Jukema, JW, Caulfield, MJ, Avery, CL, Griffin, P, Feng, Q, Taylor, KD, Li, G, Evans, DS, Smith, AV, de Keyser, CE, Johnson, AD, de Craen, AJM, Stott, DJ, Buckley, BM, Ford, I, Westendorp, RGJ, Sattar, N, Munroe, PB, Sever, P, Poulter, N, Stanton, A, Shields, DC, O'Brien, E, Shaw-Hawkins, S, Chen, Y-DI, Nickerson, DA, Smith, JD, Dube, MP, Boekholdt, SM, Hovingh, GK, Kastelein, JJP, McKeigue, PM, Betteridge, J, Neil, A, Durrington, PN, Doney, A, Carr, F, Morris, A, McCarthy, MI, Groop, L, Ahlqvist, E, Bis, JC, Rice, K, Smith, NL, Lumley, T, Whitsel, EA, Stuermer, T, Boerwinkle, E, Ngwa, JS, O'Donnell, CJ, Vasan, RS, Wei, W-Q, Wilke, RA, Liu, C-T, Sun, F, Guo, X, Heckbert, SR, Post, W, Sotoodehnia, N, Arnold, AM, Stafford, JM, Ding, J, Herrington, DM, Kritchevsky, SB, Eiriksdottir, G, Launer, LJ, Harris, TB, Chu, AY, Giulianini, F, MacFadyen, JG, Barratt, BJ, Nyberg, F, Uitterlinden, AG, Hofman, A, Rivadeneira, F, Emilsson, V, Franco, OH, Ridker, PM, Gudnason, V, Liu, Y, Denny, JC, Ballantyne, CM, Rotter, JI, Cupples, LA, Psaty, BM, Palmer, CNA, Colhoun, HM, Hitman, G

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Immunoprofile of MITF, tyrosinase, Melan-A, and MAGE-1 in HMB45-negative melanomas von XIAOWEI XU, CHU, Albert Y, PASHA, Terry L, ELDER, David E, ZHANG, Paul J

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Immunoglobulin Heavy Chain Gene Analysis in Lymphomas: A Multi-Center Study Demonstrating the Heterogeneity of Performance of Polymerase Chain Reaction Assays von Bagg, Adam, Braziel, Rita M, Arber, Daniel A, Bijwaard, Karen E, Chu, Albert Y

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Pleiotropic genes for metabolic syndrome and inflammation von Kraja, AT, Chasman, DI, North, KE, Reiner, AP, Yanek, LR, Kilpelainen, TO, Smith, JA, Dehghan, A, Dupuis, J, Johnson, AD, Feitosa, MF, Tekola-Ayele, F, Chu, AY, Nolte, IM, Dastani, Z, Morris, A, Pendergrass, SA, Sun, YV, Ritchie, MD, Vaez, A, Lin, H, Ligthart, S, Marullo, L, Rohde, R, Shao, Y, Ziegler, MA, Im, HK, Schnabel, RB, Jorgensen, T, Jorgensen, ME, Hansen, T, Pedersen, O, Stolk, RP, Snieder, H, Hofman, A, Uitterlinden, AG, Franco, OH, Ikram, MA, Richards, JB, Rotimi, C, Wilson, JG, Lange, L, Ganesh, SK, Nalls, M, Rasmussen-Torvik, LJ, Pankow, JS, Coresh, J, Tang, W, Kao, WHL, Boerwinkle, E, Morrison, AC, Ridker, PM, Becker, DM, Rotter, JI, Kardia, SLR, Loos, RJF, Larson, MG, Hsu, Y-H, Province, MA, Tracy, R, Voight, BF, Vaidya, D, O'Donnell, CJ, Benjamin, EJ, Alizadeh, BZ, Prokopenko, I, Meigs, JB, Borecki, IB

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No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels von Scott, RA, Chu, AY, Grarup, N, Manning, AK, Hivert, M-F, Toenjes, A, Yesupriya, A, Barnes, D, Bouatia-Naji, N, Glazer, NL, Jackson, AU, Kutalik, Z, Marek, D, Rasmussen-Torvik, LJ, Stringham, HM, Tanaka, T, Aadahl, M, Arking, DE, Bergmann, S, Boerwinkle, E, Bonnycastle, LL, Bornstein, SR, Brunner, E, Bumpstead, SJ, Brage, S, Chen, H, Chen, Y-DI, Chines, PS, Collins, FS, Couper, DJ, Dennison, EM, Dowling, NF, Ekelund, U, Erdos, MR, Forouhi, NG, Fox, CS, Goodarzi, MO, Graessler, J, Gustafsson, S, Hallmans, G, Hansen, T, Hingorani, A, Holloway, JW, Hu, FB, Isomaa, B, Jameson, KA, Johansson, I, Jonsson, A, Jorgensen, T, Kivimaki, M, Kovacs, P, Kumari, M, Kuusisto, J, Laakso, M, Lecoeur, C, Levy-Marchal, C, Li, G, Loos, RJF, Lyssenko, V, Marmot, M, Marques-Vidal, P, Morken, MA, Mueller, G, North, KE, Pankow, JS, Payne, F, Prokopenko, I, Psaty, BM, Renstrom, F, Rice, K, Rotter, JI, Sandholt, CH, Sayer, AA, Shrader, P, Schwarz, PEH, Siscovick, DS, Stancakova, A, Stumvoll, M, Teslovich, TM, Waeber, G, Williams, GH, Witte, DR, Wood, AR, Xie, W, Boehnke, M, Cooper, C, Ferrucci, L, Froguel, P, Groop, L, Walker, M, Watanabe, RM, Pedersen, O, Meigs, JB, Ingelsson, E, Barroso, I, Florez, JC, Franks, PW, Dupuis, J, Wareham, NJ, Langenberg, C

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Fatal Dog Maulings Associated With Infant Swings von Chu, Albert Y., Ripple, Mary G., Allan, Carol H., Thogmartin, Jon R., Fowler, David R.

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Lipoma of the tuber cinereum von Chu, Albert Y, Rorke, Lucy B, Hood, Ian C

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Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies von Gorski, M, Rasheed, H, Teumer, A, Thomas, LF, Graham, SE, Sveinbjornsson, G, Winkler, TW, Günther, F, Stark, KJ, Chai, JF, Tayo, BO, Wuttke, M, Li, Y, Tin, A, Ahluwalia, TS, Ärnlöv, J, Åsvold, BO, Bakker, SJL, Banas, B, Bansal, N, Biggs, ML, Biino, G, Böhnke, M, Boerwinkle, E, Bottinger, EP, Brenner, H, Brumpton, B, Carroll, RJ, Chaker, L, Chalmers, J, Chee, ML, Cheng, CY, Chu, AY, Ciullo, M, Cocca, M, Cook, JP, Coresh, J, Cusi, D, de Borst, MH, Degenhardt, F, Eckardt, KU, Endlich, K, Evans, MK, Feitosa, MF, Franke, A, Freitag-Wolf, S, Fuchsberger, C, Gampawar, P, Gansevoort, RT, Ghanbari, M, Ghasemi, S, Giedraitis, V, Gieger, C, Gudbjartsson, DF, Hallan, S, Hamet, P, Hishida, A, Ho, K, Hofer, E, Holleczek, B, Holm, H, Hoppmann, A, Horn, K, Hutri-Kähönen, N, Hveem, K, Hwang, SJ, Ikram, MA, Josyula, NS, Jung, B, Kähönen, M, Karabegović, I, Khor, CC, Koenig, W, Kramer, H, Krämer, BK, Kühnel, B, Kuusisto, J, Laakso, M, Lange, LA, Lehtimäki, T, Li, M, Lieb, W, Lind, L, Lindgren, CM, Loos, RJF, Lukas, MA, Lyytikäinen, LP, Mahajan, A, Matias-Garcia, PR, Meisinger, C, Meitinger, T, Melander, O, Milaneschi, Y, Mishra, PP, Mononen, N, Morris, AP, Mychaleckyj, JC, Nadkarni, GN, Naito, M, Woodward, Mark

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Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline von Gorski, M, Jung, B, Li, Y, Matias-Garcia, PR, Wuttke, M, Coassin, S, Thio, CHL, Kleber, ME, Winkler, TW, Wanner, V, Chai, JF, Chu, AY, Cocca, M, Feitosa, MF, Ghasemi, S, Hoppmann, A, Horn, K, Li, M, Nutile, T, Scholz, M, Sieber, KB, Teumer, A, Tin, A, Wang, J, Tayo, BO, Ahluwalia, TS, Almgren, P, Bakker, SJL, Banas, B, Bansal, N, Biggs, ML, Boerwinkle, E, Bottinger, EP, Brenner, H, Carroll, RJ, Chalmers, J, Chee, ML, Cheng, CY, Coresh, J, de Borst, MH, Degenhardt, F, Eckardt, KU, Endlich, K, Franke, A, Freitag-Wolf, S, Gampawar, P, Gansevoort, RT, Ghanbari, M, Gieger, C, Hamet, P, Ho, K, Hofer, E, Holleczek, B, Xian Foo, VH, Hutri-Kähönen, N, Hwang, SJ, Ikram, MA, Josyula, NS, Kähönen, M, Khor, CC, Koenig, W, Kramer, H, Krämer, BK, Kühnel, B, Lange, LA, Lehtimäki, T, Lieb, W, Alizadeh, BZ, Boezen, HM, Franke, L, van der Harst, P, Navis, G, Rots, M, Snieder, H, Swertz, M, Wolffenbuttel, BHR, Wijmenga, C, Abecasis, G, Baras, A, Cantor, M, Coppola, G, Economides, A, Lotta, LA, Overton, JD, Reid, JG, Shuldiner, A, Beechert, C, Forsythe, C, Fuller, ED, Gu, Z, Lattari, M, Lopez, A, Schleicher, TD, Padilla, MS, Toledo, K, Widom, L, Wolf, SE, Pradhan, M, Manoochehri, K, Woodward, Mark

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Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions von Shungin, D, Deng, WQ, Varga, TV, Luan, J, Mihailov, E, Metspalu, A, GIANT Consortium, Morris, AP, Forouhi, NG, Lindgren, C, Magnusson, PKE, Pedersen, NL, Hallmans, G, Chu, AY, Justice, AE, Graff, M, Winkler, TW, Rose, LM, Langenberg, C, Cupples, LA, Ridker, PM, Wareham, NJ, Ong, KK, Loos, RJF, Chasman, DI, Ingelsson, E, Kilpeläinen, TO, Scott, RA, Mägi, R, Paré, G, Franks, PW

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