Abuse liability and therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7‐hydroxymitragynine von Hemby, Scott E., McIntosh, Scot, Leon, Francisco, Cutler, Stephen J., McCurdy, Christopher R.

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Anionic phospholipids control mechanisms of GPCR-G protein recognition von Thakur, Naveen, Ray, Arka P., Sharp, Liam, Jin, Beining, Duong, Alexander, Pour, Niloofar Gopal, Obeng, Samuel, Wijesekara, Anuradha V., Gao, Zhan-Guo, McCurdy, Christopher R., Jacobson, Kenneth A., Lyman, Edward, Eddy, Matthew T.

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Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkalo... von Obeng, Samuel, Kamble, Shyam H, Reeves, Morgan E, Restrepo, Luis F, Patel, Avi, Behnke, Mira, Chear, Nelson J.-Y, Ramanathan, Surash, Sharma, Abhisheak, León, Francisco, Hiranita, Takato, Avery, Bonnie A, McMahon, Lance R, McCurdy, Christopher R

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Plant growth and phytoactive alkaloid synthesis in kratom [Mitragyna speciosa (Korth.)] in response to varying radiance von Zhang, Mengzi, Sharma, Abhisheak, León, Francisco, Avery, Bonnie, Kjelgren, Roger, McCurdy, Christopher R, Pearson, Brian J

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The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in rats von Hong, Weimin Conrad, Yano, Hideaki, Hiranita, Takato, Chin, Frederick T., McCurdy, Christopher R., Su, Tsung-Ping, Amara, Susan G., Katz, Jonathan L.

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Activity of Mitragyna speciosa (“Kratom”) Alkaloids at Serotonin Receptors von León, Francisco, Obeng, Samuel, Mottinelli, Marco, Chen, Yiming, King, Tamara I, Berthold, Erin C, Kamble, Shyam H, Restrepo, Luis F, Patel, Avi, Gamez-Jimenez, Lea R, Lopera-Londoño, Carolina, Hiranita, Takato, Sharma, Abhisheak, Hampson, Aidan J, Canal, Clinton E, McMahon, Lance R, McCurdy, Christopher R

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Fatty acid binding protein 7 plays an important modulatory sex-dependent role on brain endocannabinoid levels and THC metabolism von Penman, Samantha L, Senetra, Alexandria S, Roeder, Nicole M, Richardson, Brittany J, Pareek, Ojas, Owada, Yuji, Kagawa, Yoshiteru, Gold, Mark S, McCurdy, Christopher R, Sharma, Abhisheak, Thanos, Panayotis K

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Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids von Kamble, Shyam H., Sharma, Abhisheak, King, Tamara I., Berthold, Erin C., León, Francisco, Meyer, P. Katharina L., Kanumuri, Siva Rama Raju, McMahon, Lance R., McCurdy, Christopher R., Avery, Bonnie A.

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Self‐treatment of opioid withdrawal using kratom (Mitragynia speciosa korth) von Boyer, Edward W., Babu, Kavita M., Adkins, Jessica E., McCurdy, Christopher R., Halpern, John H.

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Searching for a Signal: Self-Reported Kratom Dose-Effect Relationships Among a Sample of US Adults With Regular Kratom Use Histories von Smith, Kirsten E, Rogers, Jeffrey M, Dunn, Kelly E, Grundmann, Oliver, McCurdy, Christopher R, Schriefer, Destiny, Epstein, David H

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Effects of Nutrient Fertility on Growth and Alkaloidal Content in Mitragyna speciosa (Kratom) von Zhang, Mengzi, Sharma, Abhisheak, León, Francisco, Avery, Bonnie, Kjelgren, Roger, McCurdy, Christopher R, Pearson, Brian J

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Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain von Wilson, Lisa L, Alleyne, Amy R, Eans, Shainnel O, Cirino, Thomas J, Stacy, Heather M, Mottinelli, Marco, Intagliata, Sebastiano, McCurdy, Christopher R, McLaughlin, Jay P

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Sigma Receptor Ligands Prevent COVID Mortality In Vivo: Implications for Future Therapeutics von Berkowitz, Reed L, Bluhm, Andrew P, Knox, Glenn W, McCurdy, Christopher R, Ostrov, David A, Norris, Michael H

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Examining the paradoxical effects of kratom: a narrative inquiry von Smith, Kirsten E, Feldman, Jeffrey D, Dunn, Kelly E, McCurdy, Christopher R, Weiss, Stephanie T, Grundmann, Oliver, Garcia-Romeu, Albert, Nichels, Janeen, Epstein, David H

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Variations in mitragynine content in the naturally growing Kratom (Mitragyna speciosa) population of Thailand von Leksungnoen, Nisa, Andriyas, Tushar, Ngernsaengsaruay, Chatchai, Uthairatsamee, Suwimon, Racharak, Phruet, Sonjaroon, Weerasin, Kjelgren, Roger, Pearson, Brian J., McCurdy, Christopher R., Sharma, Abhisheak

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Effects of nalfurafine on the reinforcing, thermal antinociceptive, and respiratory-depressant effects of oxycodone: modeling an abuse-deterrent opioid analgesic in rats von Townsend, E. Andrew, Naylor, Jennifer E., Negus, S. Stevens, Edwards, Shelley R., Qureshi, Hina N., McLendon, Hunter W., McCurdy, Christopher R., Kapanda, Coco N., do Carmo, Jussara M., da Silva, Fernanda S., Hall, John E., Sufka, Kenneth J., Freeman, Kevin B.

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Effects of the sigma-1 receptor agonist blarcamesine in a murine model of fragile X syndrome: neurobehavioral phenotypes and receptor occupancy von Reyes, Samantha T., Deacon, Robert M. J., Guo, Scarlett G., Altimiras, Francisco J., Castillo, Jessa B., van der Wildt, Berend, Morales, Aimara P., Park, Jun Hyung, Klamer, Daniel, Rosenberg, Jarrett, Oberman, Lindsay M., Rebowe, Nell, Sprouse, Jeffrey, Missling, Christopher U., McCurdy, Christopher R., Cogram, Patricia, Kaufmann, Walter E., Chin, Frederick T.

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Growing pains with kratom: experiences discussed in subreddits contrast with satisfaction expressed in surveys von Rogers, Jeffrey M, Colvin, Kayla, Epstein, David H, Grundmann, Oliver, McCurdy, Christopher R, Smith, Kirsten E

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Characterization of Sigma 1 Receptor Antagonist CM-304 and Its Analog, AZ-66: Novel Therapeutics Against Allodynia and Induced Pain von Cirino, Thomas J, Eans, Shainnel O, Medina, Jessica M, Wilson, Lisa L, Mottinelli, Marco, Intagliata, Sebastiano, McCurdy, Christopher R, McLaughlin, Jay P

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SN79, a sigma receptor ligand, blocks methamphetamine-induced microglial activation and cytokine upregulation von Robson, Matthew J., Turner, Ryan C., Naser, Zachary J., McCurdy, Christopher R., Huber, Jason D., Matsumoto, Rae R.

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