Lactococcus lactis Delivery of Surface Layer Protein A Protects Mice from Colitis by Re-Setting Host Immune Repertoire von Arukha, Ananta Prasad, Freguia, Christian Furlan, Mishra, Meerambika, Jha, Jyoti K., Kariyawasam, Subhashinie, Fanger, Neil A., Zimmermann, Ellen M., Fanger, Gary R., Sahay, Bikash

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Maternal treatment with oral intestinal alkaline phosphatase mitigates high fat diet-induced cognitive disorders in offspring mice von Furlan Freguia, Christian, Marriott, Amber, Gill, Daphne, Kaleko, Michael

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Recombinant canine B-domain–deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model von Sabatino, Denise E., Freguia, Christian Furlan, Toso, Raffaella, Santos, Andrey, Merricks, Elizabeth P., Kazazian, Haig H., Nichols, Timothy C., Camire, Rodney M., Arruda, Valder R.

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Tissue factor–protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation von Badeanlou, Leylla, Furlan-Freguia, Christian, Yang, Guang, Ruf, Wolfram, Samad, Fahumiya

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Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles von Rothmeier, Andrea S, Marchese, Patrizia, Petrich, Brian G, Furlan-Freguia, Christian, Ginsberg, Mark H, Ruggeri, Zaverio M, Ruf, Wolfram

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P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice von Furlan-Freguia, Christian, Marchese, Patrizia, Gruber, András, Ruggeri, Zaverio M, Ruf, Wolfram

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Treatment with a Lactococcus lactis that chromosomally express E. coli cfaI mitigates salivary flow loss in a Sjögren’s syndrome-like disease von Akgul, Ali, Freguia, Christian Furlan, Maddaloni, Massimo, Hoffman, Carol, Voigt, Alexandria, Nguyen, Cuong Q., Fanger, Neil A., Fanger, Gary R., Pascual, David W.

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Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality von Niessen, Frank, Furlan-Freguia, Christian, Fernández, José A., Mosnier, Laurent O., Castellino, Francis J., Weiler, Hartmut, Rosen, Hugh, Griffin, John H., Ruf, Wolfram

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Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation von Niessen, Frank, Schaffner, Florence, Furlan-Freguia, Christian, Pawlinski, Rafal, Bhattacharjee, Gourab, Chun, Jerold, Derian, Claudia K., Andrade-Gordon, Patricia, Rosen, Hugh, Ruf, Wolfram

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1140 – Syn-007, an Oral Beta-Lactamase Prevents Gut Microbime Dysbiosis Caused by Oral Amoxicillin and Oral Amoxicillin/Clavulanate Without Affecting Amoxicillin Systemic Absorptio... von Connelly, Sheila, Freguia, Christian Furlan, Fanelli, Brian C., Hasan, Nur A., Colwell, Rita, Kaleko, Michael

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Sa1839 - Orally Delivered Beta-Lactamase Prevents Gut Microbiome Dysbiosis Caused by IV and Oral Antibiotics and Mitigates Propagation of Antibiotic Resistance in Porcine and Canin... von Kaleko, Michael, Freguia, Christian Furlan, Fanelli, Brian, Hasan, Nur A., Colwell, Rita, Connelly, Sheila

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Organ-Specific Protection Against Lipopolysaccharide-Induced Vascular Leak Is Dependent on the Endothelial Protein C Receptor von von Drygalski, Annette, Furlan-Freguia, Christian, Ruf, Wolfram, Griffin, John H, Mosnier, Laurent O

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332g - An Orally Delivered Beta-Lactamase Protects the Gut Microbiome from Antibiotic-Mediated Damage and Mitigates the Propagation of Antibiotic-Resistance Genes in a Porcine Dysb... von Connelly, Sheila, Freguia, Christian Furlan, Subramanian, Poorani, Hasan, Nur A., Colwell, Rita R., Kaleko, Michael

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Characterization of mild coagulation factor VII deficiency: activity and clearance of the Arg315Trp and Arg315Lys variants in the Cys310-Cys329 loop (c170s) von Furlan Freguia, C, Toso, R, Pollak, ES, Arruda, VR, Pinotti, M, Bernardi, F

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Variation of factor VII 140s and 170s loops in fishes: evolutionary aspects and comparison with mutations found in FVII deficiency von Furlan Freguia, Christian, Toso, Raffaella, Ferraresi, Paolo, Pinotti, Mirko, Bernardi, Francesco

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An Orally Delivered Beta-Lactamase Protects the Gut Microbiome from Antibiotic-Mediated Damage and Mitigates the Propagation of Antibiotic-Resistance Genes in a Porcine Dysbiosis M... von Connelly, Sheila, Freguia, Christian Furlan, Subramanian, Poorani, Hasan, Nur A, Colwell, Rita R, Kaleko, Michael

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Vascular and dendritic cell coagulation signaling in sepsis progression von RUF, W., FURLAN‐FREGUIA, C., NIESSEN, F.

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673. Novel Delayed-Release Formulation of an Oral β-Lactamase Prevents Gut Microbiome Damage and Attenuates Antibiotic Resistance Caused by Oral Amoxicillin/Clavulanate without Int... von Connelly, Sheila, Furlan-Freguia, Christian, Fanelli, Brian, Hasan, Nur A, Colwell, Rita R, Kaleko, Michael

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A Crucial Role for Caspase 1 in Thrombo-Inflammatory Microparticle Release von Rothmeier, Andrea S, Marchese, Patrizia, Furlan-Freguia, Christian, Petrich, Brian G., Ginsberg, Mark H., Ruggeri, Zaverio M, Ruf, Wolfram

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620. Oral β-Lactamase Therapies Prevent Microbiome Damage and Attenuate Antibiotic Resistance From IV and Oral Antibiotics in Large Animal Models of Antibiotic-Mediated Gut Dysbios... von Connelly, Sheila, Furlan-Freguia, Christian, Fanelli, Brian, Hasan, Nur A, Colwell, Rita R, Kaleko, Michael

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