Endoplasmic Reticulum Stress and Oxidative Stress: A Vicious Nexus Implicated in Bowel Disease Pathophysiology von Chong, Wai Chin, Shastri, Madhur D, Eri, Rajaraman

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Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas von Przystal, Justyna M, Cianciolo Cosentino, Chiara, Yadavilli, Sridevi, Zhang, Jie, Laternser, Sandra, Bonner, Erin R, Prasad, Rachna, Dawood, Adam A, Lobeto, Nina, Chin Chong, Wai, Biery, Matt C, Myers, Carrie, Olson, James M, Panditharatna, Eshini, Kritzer, Bettina, Mourabit, Sulayman, Vitanza, Nicholas A, Filbin, Mariella G, de Iuliis, Geoffry N, Dun, Matthew D, Koschmann, Carl, Cain, Jason E, Grotzer, Michael A, Waszak, Sebastian M, Mueller, Sabine, Nazarian, Javad

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Zebrafish-A Suitable Model for Rapid Translation of Effective Therapies for Pediatric Cancers von Roy, Debasish, Subramaniam, Bavani, Chong, Wai Chin, Bornhorst, Miriam, Packer, Roger J, Nazarian, Javad

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Lessons learned from the developmental origins of childhood renal cancer von Chong, Wai Chin, Cain, Jason E.

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Role of Oxidative Stress in the Pathology and Management of Human Tuberculosis von O’Toole, Ronan F., Eri, Rajaraman, Patel, Rahul P., Peterson, Gregory M., Dua, Kamal, Chong, Wai Chin, Shukla, Shakti Dhar, Shastri, Madhur D., Hansbro, Philip M.

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The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders von Chong, Wai Chin, Shastri, Madhur D, Peterson, Gregory M, Patel, Rahul P, Pathinayake, Prabuddha S, Dua, Kamal, Hansbro, Nicole G, Hsu, Alan C, Wark, Peter A, Shukla, Shakti Dhar, Johansen, Matt D, Schroder, Kate, Hansbro, Philip M

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An Appraisal of the Current Scenario in Vaccine Research for COVID-19 von Chong, Wai Chin, Chellappan, Dinesh K., Shukla, Shakti D., Peterson, Gregory M., Patel, Rahul P., Jha, Niraj Kumar, Eri, Rajaraman D., Dua, Kamal, Tambuwala, Murtaza M., Shastri, Madhur D.

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Consequence of distinctive expression of MUC2 in colorectal cancers: How much is actually bad? von Gundamaraju, Rohit, Chong, Wai Chin

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Interplay between Endoplasmic Reticular Stress and Survivin in Colonic Epithelial Cells von Gundamaraju, Rohit, Vemuri, Ravichandra, Chong, Wai Chin, Myers, Stephen, Norouzi, Shaghayegh, Shastri, Madhur D, Eri, Rajaraman

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Streptococcus Thermophilus UASt-09 Upregulates Goblet Cell Activity in Colonic Epithelial Cells to a Greater Degree than other Probiotic Strains von Shastri, Madhur D., Chong, Wai Chin, Vemuri, Ravichandra, Martoni, Christopher J., Adhikari, Santosh, Bhullar, Harinder, Kunde, Dale, Tristram, Stephen G., Eri, Rajaraman D.

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Abstract 1163: Histone deacetylase inhibitors as potential differentiation therapy in lung adenocarcinoma von Chong, Wai Chin, Vaghjiani, Vijesh, Cain, Jason Edward

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Smoking and COVID-19: What we know so far von Shastri, Madhur D., Shukla, Shakti D., Chong, Wai Chin, KC, Rajendra, Dua, Kamal, Patel, Rahul P., Peterson, Gregory M., O'Toole, Ronan F.

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Abstract 3029: Functional genomics pipeline reveals therapeutic dependencies in diffuse intrinsic pontine glioma von Parackal, Sarah, Bradshaw, Gabrielle, Sun, Claire, Chong, Wai Chin, Daniel, Paul, Jayasekara, Samantha, Crombie, Duncan, Firestein, Ron, Cain, Jason

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ATRT-22. HIGH-THROUGHPUT DRUG SCREENING OF FDA-APPROVED CANCER DRUGS REVEALS POTENTIAL THERAPEUTIC APPROACHES FOR ATYPICAL TERATOID RHABDOID TUMOUR von Chong, Wai Chin, Zhukova, Nataliya, Wood, Paul, Downie, Peter A, Cain, Jason E

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ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma von Jackson, Evangeline R, Duchatel, Ryan J, Staudt, Dilana E, Persson, Mika L, Mannan, Abdul, Yadavilli, Sridevi, Parackal, Sarah, Game, Shaye, Chong, Wai Chin, Jayasekara, W Samantha Nilanthi, Le Grand, Marion, Kearney, Padraic S, Douglas, Alicia M, Findlay, Izac J, Germon, Zacary P, McEwen, Holly P, Beitaki, Tyrone S, Patabendige, Adjanie, Skerrett-Byrne, David A, Nixon, Brett, Smith, Nathan D, Day, Bryan, Manoharan, Neevika, Nagabushan, Sumanth, Hansford, Jordan R, Govender, Dinisha, McCowage, Geoffrey B, Firestein, Ron, Howlett, Meegan, Endersby, Raelene, Gottardo, Nicholas G, Alvaro, Frank, Waszak, Sebastian M, Larsen, Martin R, Colino-Sanguino, Yolanda, Valdés-Mora, Fatima, Rakotomalala, Andria, Meignan, Samuel, Pasquier, Eddy, Andre, Nicolas, Hulleman, Esther, Eisenstat, David D, Vitanza, Nicholas A, Nazarian, Javad, Koschmann, Carl, Mueller, Sabine, Cain, Jason E, Dun, Matthew D

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Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities von Sun, Claire Xin, Daniel, Paul, Bradshaw, Gabrielle, Shi, Hui, Loi, Melissa, Chew, Nicole, Parackal, Sarah, Tsui, Vanessa, Liang, Yuqing, Koptyra, Mateusz, Adjumain, Shazia, Sun, Christie, Chong, Wai Chin, Fernando, Dasun, Drinkwater, Caroline, Tourchi, Motahhareh, Habarakada, Dilru, Sooraj, Dhanya, Carvalho, Diana, Storm, Phillip B., Baubet, Valerie, Sayles, Leanne C., Fernandez, Elisabet, Nguyen, Thy, Pörksen, Mia, Doan, Anh, Crombie, Duncan E., Panday, Monty, Zhukova, Nataliya, Dun, Matthew D., Ludlow, Louise E., Day, Bryan, Stringer, Brett W., Neeman, Naama, Rubens, Jeffrey A., Raabe, Eric H., Vinci, Maria, Tyrrell, Vanessa, Fletcher, Jamie I., Ekert, Paul G., Dumevska, Biljana, Ziegler, David S., Tsoli, Maria, Syed Sulaiman, Nur Farhana, Loh, Amos Hong Pheng, Low, Sharon Yin Yee, Sweet-Cordero, E. Alejandro, Monje, Michelle, Resnick, Adam, Jones, Chris, Downie, Peter, Williams, Bryan, Rosenbluh, Joseph, Gough, Daniel, Cain, Jason E., Firestein, Ron

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ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma von Jackson, Evangeline R, Duchatel, Ryan J, Staudt, Dilana E, Persson, Mika L, Mannan, Abdul, Yadavilli, Sridevi, Parackal, Sarah, Game, Shaye, Chong, Wai Chin, Jayasekara, W Samantha Nilanthi, Le Grand, Marion, Kearney, Padraic S, Douglas, Alicia M, Findlay, Izac J, Germon, Zacary P, McEwen, Holly P, Beitaki, Tyrone S, Patabendige, Adjanie, Skerrett-Byrne, David A, Nixon, Brett, Smith, Nathan D, Day, Bryan, Manoharan, Neevika, Nagabushan, Sumanth, Hansford, Jordan R, Govender, Dinisha, McCowage, Geoffrey B, Firestein, Ron, Howlett, Meegan, Nazarian, Javad

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Ligand-dependent hedgehog signaling maintains an undifferentiated, malignant osteosarcoma phenotype von Vaghjiani, Vijesh G., Cochrane, Catherine R., Jayasekara, W. Samantha N., Chong, Wai Chin, Szczepny, Anette, Kumar, Beena, Martelotto, Luciano G., McCaw, Andrew, Carey, Kirstyn, Kansara, Maya, Thomas, David M., Walkley, Carl, Mudge, Stuart, Gough, Daniel J., Downie, Peter A., Peacock, Craig D., Matsui, William, Watkins, D. Neil, Cain, Jason E.

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DIPG-18. IDENTIFICATION OF TARGETABLE PATHWAY DEPENDENCIES IN DIFFUSE INTRINSIC PONTINE GLIOMA von Parackal, Sarah, Chong, Wai Chin, Bradshaw, Gabrielle, Sun, Claire, Daniel, Paul, Roussel, Enola, Jayasekara, Samantha, Crombie, Duncan, Firestein, Ron, Cain, Jason

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Bitter melon protects against ER stress in LS174T colonic epithelial cells von Kunde, Dale A, Chong, Wai Chin, Nerurkar, Prathiba V, Ahuja, Kiran D K, Just, Jeremy, Smith, Jason A, Guven, Nuri, Eri, Rajaraman D

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