Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers von Li, Xinyuan, Fang, Pu, Mai, Jietang, Choi, Eric T, Wang, Hong, Yang, Xiao-feng

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Targeting mitochondrial fission as a potential therapeutic for abdominal aortic aneurysm von Cooper, Hannah A, Cicalese, Stephanie, Preston, Kyle J, Kawai, Tatsuo, Okuno, Keisuke, Choi, Eric T, Kasahara, Shingo, Uchida, Haruhito A, Otaka, Nozomu, Scalia, Rosario, Rizzo, Victor, Eguchi, Satoru

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Early hyperlipidemia promotes endothelial activation via a caspase-1-sirtuin 1 pathway von Yin, Ying, Li, Xinyuan, Sha, Xiaojin, Xi, Hang, Li, Ya-Feng, Shao, Ying, Mai, Jietang, Virtue, Anthony, Lopez-Pastrana, Jahaira, Meng, Shu, Tilley, Douglas G, Monroy, M Alexandra, Choi, Eric T, Thomas, Craig J, Jiang, Xiaohua, Wang, Hong, Yang, Xiao-Feng

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Endothelial Immunity Trained by Coronavirus Infections, DAMP Stimulations and Regulated by Anti-Oxidant NRF2 May Contribute to Inflammations, Myelopoiesis, COVID-19 Cytokine Storms... von Shao, Ying, Saredy, Jason, Xu, Keman, Sun, Yu, Saaoud, Fatma, Drummer, Charles, Lu, Yifan, Luo, Jin J., Lopez-Pastrana, Jahaira, Choi, Eric T., Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng

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Homocysteine-methionine cycle is a metabolic sensor system controlling methylation-regulated pathological signaling von Shen, Wen, Gao, Chao, Cueto, Ramon, Liu, Lu, Fu, Hangfei, Shao, Ying, Yang, William Y., Fang, Pu, Choi, Eric T., Wu, Qinghua, Yang, Xiaofeng, Wang, Hong

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Hyperhomocysteinemia potentiates hyperglycemia-induced inflammatory monocyte differentiation and atherosclerosis von Fang, Pu, Zhang, Daqing, Cheng, Zhongjian, Yan, Chenghui, Jiang, Xiaohua, Kruger, Warren D, Meng, Shu, Arning, Erland, Bottiglieri, Teodoro, Choi, Eric T, Han, Yaling, Yang, Xiao-Feng, Wang, Hong

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MICU1 Motifs Define Mitochondrial Calcium Uniporter Binding and Activity von Hoffman, Nicholas E., Chandramoorthy, Harish C., Shamugapriya, Santhanam, Zhang, Xueqian, Rajan, Sudarsan, Mallilankaraman, Karthik, Gandhirajan, Rajesh Kumar, Vagnozzi, Ronald J., Ferrer, Lucas M., Sreekrishnanilayam, Krishnalatha, Natarajaseenivasan, Kalimuthusamy, Vallem, Sandhya, Force, Thomas, Choi, Eric T., Cheung, Joseph Y., Madesh, Muniswamy

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GATA3, HDAC6, and BCL6 Regulate FOXP3+ Treg Plasticity and Determine Treg Conversion into Either Novel Antigen-Presenting Cell-Like Treg or Th1-Treg von Xu, Keman, Yang, William Y, Nanayakkara, Gayani Kanchana, Shao, Ying, Yang, Fan, Hu, Wenhui, Choi, Eric T, Wang, Hong, Yang, Xiaofeng

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Interleukin-19 increases angiogenesis in ischemic hind limbs by direct effects on both endothelial cells and macrophage polarization von Richards, James, Gabunia, Khatuna, Kelemen, Sheri E, Kako, Farah, Choi, Eric T, Autieri, Michael V

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Novel extracellular and nuclear caspase-1 and inflammasomes propagate inflammation and regulate gene expression: a comprehensive database mining study von Wang, Luqiao, Fu, Hangfei, Nanayakkara, Gayani, Li, Yafeng, Shao, Ying, Johnson, Candice, Cheng, Jiali, Yang, William Y, Yang, Fan, Lavallee, Muriel, Xu, Yanjie, Cheng, Xiaoshu, Xi, Hang, Yi, Jonathan, Yu, Jun, Choi, Eric T, Wang, Hong, Yang, Xiaofeng

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End-stage renal disease is different from chronic kidney disease in upregulating ROS-modulated proinflammatory secretome in PBMCs - A novel multiple-hit model for disease progressi... von Zhang, Ruijing, Saredy, Jason, Shao, Ying, Yao, Tian, Liu, Lu, Saaoud, Fatma, Yang, William Y., Sun, Yu, Johnson, Candice, Drummer, Charles, Fu, Hangfei, Lu, Yifan, Xu, Keman, Liu, Ming, Wang, Jirong, Cutler, Elizabeth, Yu, Daohai, Jiang, Xiaohua, Li, Yafeng, Li, Rongshan, Wang, Lihua, Choi, Eric T., Wang, Hong, Yang, Xiaofeng

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Procaspase-1 patrolled to the nucleus of proatherogenic lipid LPC-activated human aortic endothelial cells induces ROS promoter CYP1B1 and strong inflammation von Lu, Yifan, Nanayakkara, Gayani, Sun, Yu, Liu, Lu, Xu, Keman, Drummer, Charles, Shao, Ying, Saaoud, Fatma, Choi, Eric T., Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng

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Increased acetylation of H3K14 in the genomic regions that encode trained immunity enzymes in lysophosphatidylcholine-activated human aortic endothelial cells - Novel qualification... von Lu, Yifan, Sun, Yu, Drummer, 4th, Charles, Nanayakkara, Gayani K, Shao, Ying, Saaoud, Fatma, Johnson, Candice, Zhang, Ruijing, Yu, Daohai, Li, Xinyuan, Yang, William Y, Yu, Jun, Jiang, Xiaohua, Choi, Eric T, Wang, Hong, Yang, Xiaofeng

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Canonical Secretomes, Innate Immune Caspase-1-, 4/11-Gasdermin D Non-Canonical Secretomes and Exosomes May Contribute to Maintain Treg-Ness for Treg Immunosuppression, Tissue Repai... von Ni, Dong, Tang, TingTing, Lu, Yifan, Xu, Keman, Shao, Ying, Saaoud, Fatma, Saredy, Jason, Liu, Lu, Drummer, Charles, Sun, Yu, Hu, Wenhui, Lopez-Pastrana, Jahaira, Luo, Jin J., Jiang, Xiaohua, Choi, Eric T., Wang, Hong, Yang, Xiaofeng

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A Novel Subset of CD95(+) Pro-Inflammatory Macrophages Overcome miR155 Deficiency and May Serve as a Switch From Metabolically Healthy Obesity to Metabolically Unhealthy Obesity von Johnson, Candice, Drummer, Charles, Shan, Huimin, Shao, Ying, Sun, Yu, Lu, Yifan, Saaoud, Fatma, Xu, Keman, Nanayakkara, Gayani, Fang, Pu, Bagi, Zsolt, Jiang, Xiaohua, Choi, Eric T., Wang, Hong, Yang, Xiaofeng

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Analyses of caspase-1-regulated transcriptomes in various tissues lead to identification of novel IL-1β-, IL-18- and sirtuin-1-independent pathways von Li, Ya-Feng, Nanayakkara, Gayani, Sun, Yu, Li, Xinyuan, Wang, Luqiao, Cueto, Ramon, Shao, Ying, Fu, Hangfei, Johnson, Candice, Cheng, Jiali, Chen, Xiongwen, Hu, Wenhui, Yu, Jun, Choi, Eric T, Wang, Hong, Yang, Xiao-Feng

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Twenty Novel Disease Group-Specific and 12 New Shared Macrophage Pathways in Eight Groups of 34 Diseases Including 24 Inflammatory Organ Diseases and 10 Types of Tumors von Lai, Bin, Wang, Jiwei, Fagenson, Alexander, Sun, Yu, Saredy, Jason, Lu, Yifan, Nanayakkara, Gayani, Yang, William Y, Yu, Daohai, Shao, Ying, Drummer, 4th, Charles, Johnson, Candice, Saaoud, Fatma, Zhang, Ruijing, Yang, Qian, Xu, Keman, Mastascusa, Kevin, Cueto, Ramon, Fu, Hangfei, Wu, Susu, Sun, Lizhe, Zhu, Peiqian, Qin, Xuebin, Yu, Jun, Fan, Daping, Shen, Ying H, Sun, Jianxin, Rogers, Thomas, Choi, Eric T, Wang, Hong, Yang, Xiaofeng

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Metabolism-associated danger signal-induced immune response and reverse immune checkpoint-activated CD40 + monocyte differentiation von Dai, Jin, Fang, Pu, Saredy, Jason, Xi, Hang, Ramon, Cueto, Yang, William, Choi, Eric T, Ji, Yong, Mao, Wei, Yang, Xiaofeng, Wang, Hong

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In Vitro Study on Smart Stent for Autonomous Post-Endovascular Aneurysm Repair Surveillance von Islam, Sayemul, Song, Xiaolei, Choi, Eric T., Kim, Jungkwun, Liu, Haijun, Kim, Albert

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Experimental Data-Mining Analyses Reveal New Roles of Low-Intensity Ultrasound in Differentiating Cell Death Regulatome in Cancer and Non-cancer Cells via Potential Modulation of C... von Wang, Jiwei, Lai, Bin, Nanayakkara, Gayani, Yang, Qian, Sun, Yu, Lu, Yifan, Shao, Ying, Yu, Daohai, Yang, William Y, Cueto, Ramon, Fu, Hangfei, Zeng, Huihong, Shen, Wen, Wu, Susu, Zhang, Chunquan, Liu, Yanna, Choi, Eric T, Wang, Hong, Yang, Xiaofeng

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