Crystal structure of the effector AvrLm4–7 of Leptosphaeria maculans reveals insights into its translocation into plant cells and recognition by resistance proteins von Blondeau, Karine, Blaise, Françoise, Graille, Marc, Kale, Shiv D., Linglin, Juliette, Ollivier, Bénédicte, Labarde, Audrey, Lazar, Noureddine, Daverdin, Guillaume, Balesdent, Marie‐Hélène, Choi, Danielle H.Y., Tyler, Brett M., Rouxel, Thierry, Tilbeurgh, Herman, Fudal, Isabelle

Volltext

Defining the therapeutic selective dependencies for distinct subtypes of PI3K pathway-altered prostate cancers von Mao, Ninghui, Zhang, Zeda, Lee, Young Sun, Choi, Danielle, Rivera, Aura Agudelo, Li, Dan, Lee, Cindy, Haywood, Samuel, Chen, Xiaoping, Chang, Qing, Xu, Guotai, Chen, Hsuan-An, de Stanchina, Elisa, Sawyers, Charles, Rosen, Neal, Hsieh, Andrew C., Chen, Yu, Carver, Brett S.

Volltext

Rapid interrogation of cancer cell of origin through CRISPR editing von Feng, Weiran, Cao, Zhen, Lim, Pei Xin, Zhao, Huiyong, Luo, Hanzhi, Mao, Ninghui, Lee, Young Sun, Rivera, Aura Agudelo, Choi, Danielle, Wu, Chao, Han, Teng, Romero, Rodrigo, de Stanchina, Elisa, Carver, Brett S., Wang, Qiao, Jasin, Maria, Sawyers, Charles L.

Volltext

Prostate Organoid Cultures as Tools to Translate Genotypes and Mutational Profiles to Pharmacological Responses von Pappas, Kyrie J, Choi, Danielle, Sawyers, Charles L, Karthaus, Wouter R

Volltext

GREB1 amplifies androgen receptor output in human prostate cancer and contributes to antiandrogen resistance von Lee, Eugine, Wongvipat, John, Choi, Danielle, Wang, Ping, Lee, Young Sun, Zheng, Deyou, Watson, Philip A, Gopalan, Anuradha, Sawyers, Charles L

Volltext

Prostate Organoid Cultures as Tools to Translate Genotypes and Mutational Profiles to Pharmacological Responses von Pappas, Kyrie J., Choi, Danielle, Sawyers, Charles L., Karthaus, Wouter R.

Volltext

Juvenile Delinquents von Choi, Danielle

Volltext

Regenerative potential of prostate luminal cells revealed by single-cell analysis von Karthaus, Wouter R., Hofree, Matan, Choi, Danielle, Linton, Eliot L., Turkekul, Mesruh, Bejnood, Alborz, Carver, Brett, Gopalan, Anuradha, Abida, Wassim, Laudone, Vincent, Biton, Moshe, Chaudhary, Ojasvi, Xu, Tianhao, Masilionis, Ignas, Manova, Katia, Mazutis, Linas, Pe'er, Dana, Regev, Aviv, Sawyers, Charles L.

Volltext

Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer von Zhang, Zeda, Karthaus, Wouter R., Lee, Young Sun, Gao, Vianne R., Wu, Chao, Russo, Joshua W., Liu, Menghan, Mota, Jose Mauricio, Abida, Wassim, Linton, Eliot, Lee, Eugine, Barnes, Spencer D., Chen, Hsuan-An, Mao, Ninghui, Wongvipat, John, Choi, Danielle, Chen, Xiaoping, Zhao, Huiyong, Manova-Todorova, Katia, de Stanchina, Elisa, Taplin, Mary-Ellen, Balk, Steven P., Rathkopf, Dana E., Gopalan, Anuradha, Carver, Brett S., Mu, Ping, Jiang, Xuejun, Watson, Philip A., Sawyers, Charles L.

Volltext

Juvenile Delinquents von Choi, Danielle Narae

Volltext

Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation von Zhang, Zeda, Zhou, Chuanli, Li, Xiaoling, Barnes, Spencer D., Deng, Su, Hoover, Elizabeth, Chen, Chi-Chao, Lee, Young Sun, Zhang, Yanxiao, Wang, Choushi, Metang, Lauren A., Wu, Chao, Tirado, Carla Rodriguez, Johnson, Nickolas A., Wongvipat, John, Navrazhina, Kristina, Cao, Zhen, Choi, Danielle, Huang, Chun-Hao, Linton, Eliot, Chen, Xiaoping, Liang, Yupu, Mason, Christopher E., de Stanchina, Elisa, Abida, Wassim, Lujambio, Amaia, Li, Sheng, Lowe, Scott W., Mendell, Joshua T., Malladi, Venkat S., Sawyers, Charles L., Mu, Ping

Volltext

Aberrant Expression of ERG Promotes Resistance to Combined PI3K and AR Pathway Inhibition through Maintenance of AR Target Genes von Mao, Ninghui, Gao, Dong, Hu, Wenhuo, Hieronymus, Haley, Wang, Shangqian, Lee, Young Sun, Lee, Cindy, Choi, Danielle, Gopalan, Anuradha, Chen, Yu, Carver, Brett S

Volltext

Oncogenic ERG Represses PI3K Signaling through Downregulation of IRS2 von Mao, Ninghui, Gao, Dong, Hu, Wenhuo, Gadal, Sunyana, Hieronymus, Haley, Wang, Shangqian, Lee, Young Sun, Sullivan, Patrick, Zhang, Zeda, Choi, Danielle, Rosen, Neal, Sawyers, Charles L., Gopalan, Anuradha, Chen, Yu, Carver, Brett S.

Volltext

Abstract PO-134: Identification of the cells of origin and tumor heterogeneity in neuroendocrine prostate cancer (NEPC) by single-cell analysis von Zhao, Jimmy L., Zaidi, Samir, Chan, Joseph, Wadosky, Kristine, Karthaus, Wouter, Choi, Danielle, Rivera, Aura Agudelo, Gopalan, Anuradha, Rathkopf, Dana, Carver, Brett, Abida, Wassim, Scher, Howard, Chen, Yu, Goodrich, David, Pe’er, Dana, Sawyers, Charles L.

Volltext

Abstract 5722: Acquired stemness by luminal cells von Karthaus, Wouter, Hofree, Matan, Choi, Danielle, Linton, Eliot L., Turkekul, Mesruh, Bejnood, Alborz, Carver, Brett, Gopalan, Anuhandra, Laudone, Vincent, Biton, Moshe, Chaudhary, Ojasvi, Masilionis, Ignas, Mazutis, Linas, Pe'er, Dana, Regev, Aviv, Sawyers, Charles

Volltext

Oncogenic ERG Represses PI3K Signaling through Downregulation of IRS2 von Mao, Ninghui, Gao, Dong, Hu, Wenhuo, Gadal, Sunyana, Hieronymus, Haley, Wang, Shangqian, Lee, Young Sun, Sullivan, Patrick, Zhang, Zeda, Choi, Danielle, Rosen, Neal, Sawyers, Charles L., Gopalan, Anuradha, Chen, Yu, Carver, Brett S.

Volltext

Oncogenic ERG represses PI3K signaling through down-regulation of IRS2 von Mao, Ninghui, Gao, Dong, Hu, Wenhuo, Gadal, Sunyana, Hieronymus, Haley, Wang, Shangqian, Lee, Young Sun, Sullivan, Patrick, Zhang, Zeda, Choi, Danielle, Rosen, Neal, Sawyers, Charles L, Gopalan, Anuradha, Chen, Yu, Carver, Brett S

Volltext

Abstract 111: Tumor microenvironment derived NRG1 promotes antiandrogen resistance in prostate cancer von Zhang, Zeda, Karthaus, Wouter, Mota, Jose Mauricio, Mu, Ping, Wu, Chao, Abida, Wassim, Linton, Eliot, Lee, Young Sun, Lee, Eugine, Mao, Ninghui, Adams, Elizabeth, Choi, Danielle, Rathkopf, Dana E., Carver, Brett, Gopalan, Anuradha, Jiang, Xuejun, Watson, Philip, Sawyers, Charles

Volltext

CEBS--Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data von Waters, Michael, Stasiewicz, Stanley, Alex Merrick, B, Tomer, Kenneth, Bushel, Pierre, Paules, Richard, Stegman, Nancy, Nehls, Gerald, Yost, Kenneth J, Johnson, C. Harris, Gustafson, Scott F, Xirasagar, Sandhya, Xiao, Nianqing, Huang, Cheng-Cheng, Boyer, Paul, Chan, Denny D, Pan, Qinyan, Gong, Hui, Taylor, John, Choi, Danielle, Rashid, Asif, Ahmed, Ayazaddin, Howle, Reese, Selkirk, James, Tennant, Raymond, Fostel, Jennifer

Volltext

Crystal structure of the effector A vr L m4–7 of Leptosphaeria maculans reveals insights into its translocation into plant cells and recognition by resistance proteins von Blondeau, Karine, Blaise, Françoise, Graille, Marc, Kale, Shiv D., Linglin, Juliette, Ollivier, Bénédicte, Labarde, Audrey, Lazar, Noureddine, Daverdin, Guillaume, Balesdent, Marie‐Hélène, Choi, Danielle H.Y., Tyler, Brett M., Rouxel, Thierry, van Tilbeurgh, Herman, Fudal, Isabelle

Volltext