DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair von Sibanda, Bancinyane L., Chirgadze, Dimitri Y., Ascher, David B., Blundell, Tom L.

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CryoEM structures of human CMG–ATPγS–DNA and CMG–AND-1 complexes von Rzechorzek, Neil J, Hardwick, Steven W, Jatikusumo, Vincentius A, Chirgadze, Dimitri Y, Pellegrini, Luca

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Dimers of DNA-PK create a stage for DNA double-strand break repair von Chaplin, Amanda K., Hardwick, Steven W., Liang, Shikang, Kefala Stavridi, Antonia, Hnizda, Ales, Cooper, Lee R., De Oliveira, Taiana Maia, Chirgadze, Dimitri Y., Blundell, Tom L.

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Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats von Sibanda, Bancinyane L., Chirgadze, Dimitri Y., Blundell, Tom L.

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Expanding the Solvent Chemical Space for Self-Assembly of Dipeptide Nanostructures von Mason, Thomas O, Chirgadze, Dimitri Y, Levin, Aviad, Adler-Abramovich, Lihi, Gazit, Ehud, Knowles, Tuomas P. J, Buell, Alexander K

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The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis von Wilson, L. F. L., Dendooven, T., Hardwick, S. W., Echevarría-Poza, A., Tryfona, T., Krogh, K. B. R. M., Chirgadze, D. Y., Luisi, B. F., Logan, D. T., Mani, K., Dupree, P.

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Nanostructured films from hierarchical self-assembly of amyloidogenic proteins von Knowles, Tuomas P. J., Oppenheim, Tomas W., Buell, Alexander K., Chirgadze, Dimitri Y., Welland, Mark E.

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Structural basis for human mitochondrial tRNA maturation von Meynier, Vincent, Hardwick, Steven W., Catala, Marjorie, Roske, Johann J., Oerum, Stephanie, Chirgadze, Dimitri Y., Barraud, Pierre, Yue, Wyatt W., Luisi, Ben F., Tisné, Carine

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Structural basis for collagen recognition by the immune receptor OSCAR von Zhou, Long, Hinerman, Jennifer M., Blaszczyk, Michal, Miller, Jeanette L.C., Conrady, Deborah G., Barrow, Alexander D., Chirgadze, Dimitri Y., Bihan, Dominique, Farndale, Richard W., Herr, Andrew B.

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Crystal Structure and Molecular Imaging of the Nav Channel β3 Subunit Indicates a Trimeric Assembly von Namadurai, Sivakumar, Balasuriya, Dilshan, Rajappa, Rajit, Wiemhöfer, Martin, Stott, Katherine, Klingauf, Jurgen, Edwardson, J.Michael, Chirgadze, Dimitri Y., Jackson, Antony P.

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Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti von Saucereau, Yoann, Wilson, Thomas H., Tang, Matthew C. K., Moncrieffe, Martin C., Hardwick, Steven W., Chirgadze, Dimitri Y., Soares, Sandro G., Marcaida, Maria Jose, Gay, Nicholas J., Gangloff, Monique

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Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction von Kefala Stavridi, Antonia, Gontier, Amandine, Morin, Vincent, Frit, Philippe, Ropars, Virginie, Barboule, Nadia, Racca, Carine, Jonchhe, Sagun, Morten, Michael J, Andreani, Jessica, Rak, Alexey, Legrand, Pierre, Bourand-Plantefol, Alexa, Hardwick, Steven W, Chirgadze, Dimitri Y, Davey, Paul, De Oliveira, Taiana Maia, Rothenberg, Eli, Britton, Sebastien, Calsou, Patrick, Blundell, Tom L, Varela, Paloma F, Chaplin, Amanda K, Charbonnier, Jean-Baptiste

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A metal ion-dependent mechanism of RAD51 nucleoprotein filament disassembly von Appleby, Robert, Bollschweiler, Daniel, Chirgadze, Dimitri Y., Joudeh, Luay, Pellegrini, Luca

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Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site von Bolanos-Garcia, Victor M., Lischetti, Tiziana, Matak-Vinković, Dijana, Cota, Ernesto, Simpson, Pete J., Chirgadze, Dimitri Y., Spring, David R., Robinson, Carol V., Nilsson, Jakob, Blundell, Tom L.

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Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases von Singer, Alexander U, Rohde, John R, Lam, Robert, Skarina, Tatiana, Kagan, Olga, DiLeo, Rosa, Chirgadze, Nickolay Y, Cuff, Marianne E, Joachimiak, Andrzej, Tyers, Mike, Sansonetti, Philippe J, Parsot, Claude, Savchenko, Alexei

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A new look at sodium channel β subunits von Namadurai, Sivakumar, Yereddi, Nikitha R., Cusdin, Fiona S., Huang, Christopher L.-H., Chirgadze, Dimitri Y., Jackson, Antony P.

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Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer von Nookala, Ravi K., Langemeyer, Lars, Pacitto, Angela, Ochoa-Montaño, Bernardo, Donaldson, Jane C., Blaszczyk, Beata K., Chirgadze, Dimitri Y., Barr, Francis A., Bazan, J. Fernando, Blundell, Tom L.

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Single-particle cryo-EM at atomic resolution von Nakane, Takanori, Kotecha, Abhay, Sente, Andrija, McMullan, Greg, Masiulis, Simonas, Brown, Patricia M. G. E., Grigoras, Ioana T., Malinauskaite, Lina, Malinauskas, Tomas, Miehling, Jonas, Uchański, Tomasz, Yu, Lingbo, Karia, Dimple, Pechnikova, Evgeniya V., de Jong, Erwin, Keizer, Jeroen, Bischoff, Maarten, McCormack, Jamie, Tiemeijer, Peter, Hardwick, Steven W., Chirgadze, Dimitri Y., Murshudov, Garib, Aricescu, A. Radu, Scheres, Sjors H. W.

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The Discovery of Orally Bioavailable Tyrosine Threonine Kinase (TTK) Inhibitors: 3‑(4-(heterocyclyl)phenyl)‑1H‑indazole-5-carboxamides as Anticancer Agents von Liu, Yong, Lang, Yunhui, Patel, Narendra Kumar, Ng, Grace, Laufer, Radoslaw, Li, Sze-Wan, Edwards, Louise, Forrest, Bryan, Sampson, Peter B, Feher, Miklos, Ban, Fuqiang, Awrey, Donald E, Beletskaya, Irina, Mao, Guodong, Hodgson, Richard, Plotnikova, Olga, Qiu, Wei, Chirgadze, Nickolay Y, Mason, Jacqueline M, Wei, Xin, Lin, Dan Chi-Chia, Che, Yi, Kiarash, Reza, Madeira, Brian, Fletcher, Graham C, Mak, Tak W, Bray, Mark R, Pauls, Henry W

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Crystal Structure of the Passenger Domain of the Escherichia coli Autotransporter EspP von Khan, Shekeb, Mian, Hira S., Sandercock, Linda E., Chirgadze, Nickolay Y., Pai, Emil F.

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