Complement activation and choriocapillaris loss in early AMD: Implications for pathophysiology and therapy von Whitmore, S. Scott, Sohn, Elliott H., Chirco, Kathleen R., Drack, Arlene V., Stone, Edwin M., Tucker, Budd A., Mullins, Robert F.

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C-Reactive Protein As a Mediator of Complement Activation and Inflammatory Signaling in Age-Related Macular Degeneration von Chirco, Kathleen R, Potempa, Lawrence A

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Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration von Mulfaul, Kelly, Ozaki, Ema, Fernando, Nilisha, Brennan, Kiva, Chirco, Kathleen R., Connolly, Emma, Greene, Chris, Maminishkis, Arvydas, Salomon, Robert G., Linetsky, Mikhail, Natoli, Riccardo, Mullins, Robert F., Campbell, Matthew, Doyle, Sarah L.

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Advancements in pre-clinical development of gene editing-based therapies to treat inherited retinal diseases von Chirco, Kathleen R., Martinez, Cassandra, Lamba, Deepak A.

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Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell‐Derived Choroidal Endothelium von Songstad, Allison E., Worthington, Kristan S., Chirco, Kathleen R., Giacalone, Joseph C., Whitmore, S. Scott, Anfinson, Kristin R., Ochoa, Dalyz, Cranston, Cathryn M., Riker, Megan J., Neiman, Maurine, Stone, Edwin M., Mullins, Robert F., Tucker, Budd A.

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Timed Notch Inhibition Drives Photoreceptor Fate Specification in Human Retinal Organoids von Chew, Shereen H, Martinez, Cassandra, Chirco, Kathleen R, Kandoi, Sangeetha, Lamba, Deepak A

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Selective accumulation of the complement membrane attack complex in aging choriocapillaris von Chirco, Kathleen R., Tucker, Budd A., Stone, Edwin M., Mullins, Robert F.

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Allele-specific gene editing to rescue dominant CRX-associated LCA7 phenotypes in a retinal organoid model von Chirco, Kathleen R., Chew, Shereen, Moore, Anthony T., Duncan, Jacque L., Lamba, Deepak A.

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CRISPR-Cas9 genome engineering: Treating inherited retinal degeneration von Burnight, Erin R., Giacalone, Joseph C., Cooke, Jessica A., Thompson, Jessica R., Bohrer, Laura R., Chirco, Kathleen R., Drack, Arlene V., Fingert, John H., Worthington, Kristan S., Wiley, Luke A., Mullins, Robert F., Stone, Edwin M., Tucker, Budd A.

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Preformed Vesicle Approach to LNP Manufacturing Enhances Retinal mRNA Delivery von Eygeris, Yulia, Henderson, Michael I., Curtis, Allison G., Jozić, Antony, Stoddard, Jonathan, Reynaga, Rene, Chirco, Kathleen R., Su, Grace Li‐Na, Neuringer, Martha, Lauer, Andreas K., Ryals, Renee C., Sahay, Gaurav

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MANF delivery improves retinal homeostasis and cell replacement therapies in ageing mice von Neves, Joana, Chirco, Kathleen R., Cedron-Craft, Wendy, Chew, Shereen, Zhu, Jie, Jasper, Heinrich, Lamba, Deepak A.

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Bulk and single-cell gene expression analyses reveal aging human choriocapillaris has pro-inflammatory phenotype von Voigt, Andrew P., Whitmore, S. Scott, Mulfaul, Kelly, Chirco, Kathleen R., Giacalone, Joseph C., Flamme-Wiese, Miles J., Stockman, Adam, Stone, Edwin M., Tucker, Budd A., Scheetz, Todd E., Mullins, Robert F.

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Monomeric C-reactive protein and inflammation in age-related macular degeneration von Chirco, Kathleen R, Whitmore, S Scott, Wang, Kai, Potempa, Lawrence A, Halder, Jennifer A, Stone, Edwin M, Tucker, Budd A, Mullins, Robert F

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Preparation and evaluation of human choroid extracellular matrix scaffolds for the study of cell replacement strategies von Chirco, Kathleen R., Worthington, Kristan S., Flamme-Wiese, Miles J., Riker, Megan J., Andrade, Joshua D., Ueberheide, Beatrix M., Stone, Edwin M., Tucker, Budd A., Mullins, Robert F.

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Evaluation of serum and ocular levels of membrane attack complex and C-reactive protein in CFH-genotyped human donors von Chirco, Kathleen R., Flamme-Wiese, Miles J., Wiley, Jill S., Potempa, Lawrence A., Stone, Edwin M., Tucker, Budd A., Mullins, Robert F.

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Imidazole Compounds for Protecting Choroidal Endothelial Cells from Complement Injury von Zeng, Shemin, Wen, Kuo-Kuang, Workalemahu, Grefachew, Sohn, Elliott H., Wu, Meng, Chirco, Kathleen R., Flamme-Wiese, Miles J., Liu, Xiuying, Stone, Edwin M., Tucker, Budd A., Mullins, Robert F.

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MMP19 expression in the human optic nerve von Chirco, Kathleen R, Hazlewood, Ralph J, Miller, Kathy, Workalemahu, Grefachew, Jampol, Lee M, Lesser, G Robert, Mullins, Robert F, Kuehn, Markus H, Fingert, John H

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Monomeric C-reactive protein and inflammation in age-related macular degeneration: The role of monomeric C-reactive protein in AMD von Chirco, Kathleen R, Whitmore, S Scott, Wang, Kai, Potempa, Lawrence A, Halder, Jennifer A, Stone, Edwin M, Tucker, Budd A, Mullins, Robert F

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