Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome von McCord, Rachel Patton, Nazario-Toole, Ashley, Zhang, Haoyue, Chines, Peter S, Zhan, Ye, Erdos, Michael R, Collins, Francis S, Dekker, Job, Cao, Kan

Volltext

Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns von MOHLKE, Karen L, JACKSON, Anne U, NARISU, Narisu, ENLOE, Sareena, VALLE, Timo T, TUOMILEHTO, Jaakko, BERGMAN, Richard N, BOEHNKE, Michael, COLLINS, Francis S, SCOTT, Laura J, PECK, Erin C, SUH, Yong D, CHINES, Peter S, WATANABE, Richard M, BUCHANAN, Thomas A, CONNEELY, Karen N, ERDOS, Michael R

Volltext

Linkage disequilibrium between microsatellite markers extends beyond 1 cM on chromosome 20 in Finns von Mohlke, K L, Lange, E M, Valle, T T, Ghosh, S, Magnuson, V L, Silander, K, Watanabe, R M, Chines, P S, Bergman, R N, Tuomilehto, J, Collins, F S, Boehnke, M

Volltext

Methionine Synthase: High-Resolution Mapping of the Human Gene and Evaluation as a Candidate Locus for Neural Tube Defects von Brody, Lawrence C., Baker, Priscilla J., Chines, Peter S., Musick, Anjene, Molloy, Anne M., Swanson, Deborah A., Kirke, Peadar N., Ghosh, Soumitra, Scott, John M., Mills, James L.

Volltext

Genetic Variation Near the Hepatocyte Nuclear Factor-4α Gene Predicts Susceptibility to Type 2 Diabetes von SILANDER, Kaisa, MOHLKE, Karen L, CHINES, Peter S, ERDOS, Michael R, NARISU, Narisu, CONNEELY, Karen N, CHUN LI, FINGERLIN, Tasha E, DHANJAL, Sharanjeet K, VALLE, Timo T, BERGMAN, Richard N, TUOMILEHTO, Jaakko, SCOTT, Laura J, WATANABE, Richard M, BOEHNKE, Michael, COLLINS, Francis S, PECK, Erin C, HOLLSTEIN, Pablo, SKOL, Andrew D, JACKSON, Anne U, DELOUKAS, Panagiotis, HUNT, Sarah, STAVRIDES, George

Volltext

An expanded genome-wide association study of Type 2 diabetes in Europeans von Mägi, R, Gaulton, KJ, Kaakinen, M, Pervjakova, N, Pers, TH, Johnson, AD, Eicher, JD, Ferreira, T, Ma, C, Thorleifsson, G, Qi, L, Van Zuydam, NR, Mahajan, A, Almgren, P, Voight, BF, Müller-Nurasyid, M, Ried, JS, Rayner, WN, Robertson, N, Karssen, LC, Willems, SM, Chanda, P, Li, M, Lu, Y, Yengo, L, Jiang, L, Chheda, H, Eisele, L, Gustafsson, S, Frånberg, M, Benediktsson, R, Kong, A, Sigurðsson, G, Kerrison, ND, Luan, J, Meitinger, T, Esko, T, Liu, CT, Isomaa, B, Couper, DJ, Pankow, JS, Cornelis, MC, Kraft, P, Owen, KR, Zeggini, E, Tajes-Fernandes, J, Chines, PS, Stringham, HM, Koistinen, HA, Kinnunen, L, Sennblad, B, Mühleisen, TW, Nöthen, MM, Baldassarre, D, Gertow, K, Humphries, SE, Tremoli, E, Klopp, N, Meyer, J, Steinbach, G, Mӓnnistö, S, Tikkanen, E, Eury, E, Lobbens, S, Leander, K, Blüher, M, Kovacs, P, Maruthur, NM, Erbel, R, De Faire, U, Hamsten, A, Deloukas, P, Donnelly, PJ, Frayling, TM, Hattersley, AT, Ripatti, S, Boehm, BO, Collins, FS, Pedersen, O, Barroso, I, Froguel, P, Balkau, B, Franks, PW, Gurrea, AB, Palli, D, Altshuler, D, Groop, LC, Langenberg, C, Wareham, NJ, Florez, JC, Meigs, JB, Boerwinkle, E, Strauch, K, Metspalu, A, Palmer, CN, Hu, FB, Dupuis, J, Boehnke, M, McCarthy, MI, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium

Volltext

The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits von Voight, BF, Kang, HM, Ding, J, Palmer, CD, Sidore, C, Chines, PS, Burtt, NP, Fuchsberger, C, Li, Y, Erdmann, J, Frayling, TM, Heid, IM, Jackson, AU, Johnson, T, Kilpeläinen, TO, Lindgren, CM, Morris, AP, Prokopenko, I, Randall, JC, Saxena, R, Soranzo, N, Speliotes, EK, Teslovich, TM, Wheeler, E, Maguire, J, Parkin, M, Potter, S, Rayner, NW, Robertson, N, Stirrups, K, Winckler, W, Sanna, S, Mulas, A, Nagaraja, R, Cucca, F, Barroso, I, Deloukas, P, Loos, RJ, Kathiresan, S, Munroe, PB, Newton-Cheh, C, Pfeufer, A, Samani, NJ, Schunkert, H, Hirschhorn, JN, Altshuler, D, McCarthy, MI, Abecasis, GR, Boehnke, M

Volltext

No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels von Scott, RA, Chu, AY, Grarup, N, Manning, AK, Hivert, M-F, Toenjes, A, Yesupriya, A, Barnes, D, Bouatia-Naji, N, Glazer, NL, Jackson, AU, Kutalik, Z, Marek, D, Rasmussen-Torvik, LJ, Stringham, HM, Tanaka, T, Aadahl, M, Arking, DE, Bergmann, S, Boerwinkle, E, Bonnycastle, LL, Bornstein, SR, Brunner, E, Bumpstead, SJ, Brage, S, Chen, H, Chen, Y-DI, Chines, PS, Collins, FS, Couper, DJ, Dennison, EM, Dowling, NF, Ekelund, U, Erdos, MR, Forouhi, NG, Fox, CS, Goodarzi, MO, Graessler, J, Gustafsson, S, Hallmans, G, Hansen, T, Hingorani, A, Holloway, JW, Hu, FB, Isomaa, B, Jameson, KA, Johansson, I, Jonsson, A, Jorgensen, T, Kivimaki, M, Kovacs, P, Kumari, M, Kuusisto, J, Laakso, M, Lecoeur, C, Levy-Marchal, C, Li, G, Loos, RJF, Lyssenko, V, Marmot, M, Marques-Vidal, P, Morken, MA, Mueller, G, North, KE, Pankow, JS, Payne, F, Prokopenko, I, Psaty, BM, Renstrom, F, Rice, K, Rotter, JI, Sandholt, CH, Sayer, AA, Shrader, P, Schwarz, PEH, Siscovick, DS, Stancakova, A, Stumvoll, M, Teslovich, TM, Waeber, G, Williams, GH, Witte, DR, Wood, AR, Xie, W, Boehnke, M, Cooper, C, Ferrucci, L, Froguel, P, Groop, L, Walker, M, Watanabe, RM, Pedersen, O, Meigs, JB, Ingelsson, E, Barroso, I, Florez, JC, Franks, PW, Dupuis, J, Wareham, NJ, Langenberg, C

Volltext

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans von Maegi, R, Gaulton, KJ, Kaakinen, M, Pervjakova, N, Pers, TH, Johnson, AD, Eicher, JD, Ferreira, T, Ma, C, Thorleifsson, G, Qi, L, Van Zuydam, NR, Mahajan, A, Almgren, P, Voight, BF, Ried, JS, Rayner, NW, Robertson, N, Karssen, LC, Willems, SM, Chanda, P, Li, M, Lu, Y, Yengo, L, Jiang, L, Chheda, H, Eisele, L, Gustafsson, S, Franberg, M, Benediktsson, R, Kong, A, Sigurdsson, G, Kerrison, ND, Luan, J, Meitinger, T, Esko, T, Fox, C, Isomaa, B, Couper, DJ, Pankow, JS, Jorgensen, ME, Jorgensen, T, Cornelis, MC, Kraft, P, Sun, Q, Owen, KR, Zeggini, E, Tajes-Fernandes, J, Chines, PS, Stringham, HM, Koistinen, HA, Kinnunen, L, Sennblad, B, Baldassarre, D, Gertow, K, Humphries, SE, Tremoli, E, Klopp, N, Meyer, J, Steinbach, G, Mannisto, S, Tikkanen, E, Eury, E, Lobbens, S, Gigante, B, Leander, K, Blueher, M, Kovacs, P, Maruthur, NM, Erbel, R, Joeckel, K-H, De Faire, U, Hamsten, A, Deloukas, P, Donnelly, PJ, Frayling, TM, Hattersley, AT, Ripatti, S, Boehm, BO, Collins, FS, Pedersen, O, Barroso, I, Froguel, P, Balkau, B, Franks, PW, Gurrea, AB, Palli, D, Altshuler, D, Groop, LC, Langenberg, C, Wareham, NJ, Florez, JC, Meigs, JB, Boerwinkle, E, Strauch, K, Metspalu, A, Hu, FB, Dupuis, J, Boehnke, M, McCarthy, MI

Volltext bestellen

A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome von Di Gioia, SA, Connors, S, Matsunami, N, Cannavino, J, Rose, MF, Gilette, NM, Artoni, P, De Macena Sobreira, NL, Chan, WM, Webb, BD, Robson, CD, Cheng, L, Van Ryzin, C, Ramirez-Martinez, A, Mohassel, P, Leppert, M, Scholand, MB, Grunseich, C, Ferreira, CR, Hartman, T, Hayes, IM, Morgan, T, Markie, DM, Fagiolini, M, Swift, A, Chines, PS, Speck-Martins, CE, Collins, FS, Jabs, EW, Bönnemann, CG, Olson, EN, Carey, JC, Robertson, SP, Manoli, I, Engle, EC, Andrews, CV, Barry, BJ, Hunter, DG, Mackinnon, SE, Shaaban, S, Erazo, M, Frempong, T, Hao, K, Naidich, TP, Rucker, JC, Zhang, Z, Biesecker, BB, Bonnycastle, LL, Brewer, CC, Brooks, BP, Butman, JA, Chien, WW, Farrell, K, FitzGibbon, EJ, Gropman, AL, Hutchinson, EB

Volltext bestellen

Identification of tag single-nucleotide polymorphisms in regions with varying linkage disequilibrium von Duggal, Priya, Gillanders, Elizabeth M, Mathias, Rasika A, Ibay, Grace P, Klein, Alison P, Baffoe-Bonnie, Agnes B, Ou, Liang, Dusenberry, Ian P, Tsai, Ya-Yu, Chines, Peter S, Doan, Betty Q, Bailey-Wilson, Joan E

Volltext

Investigation of altering single-nucleotide polymorphism density on the power to detect trait loci and frequency of false positive in nonparametric linkage analyses of qualitative... von Klein, Alison P, Tsai, Ya-Yu, Duggal, Priya, Gillanders, Elizabeth M, Barnhart, Michael, Mathias, Rasika A, Dusenberry, Ian P, Turiff, Amy, Chines, Peter S, Goldstein, Janet, Wojciechowski, Robert, Hening, Wayne, Pugh, Elizabeth W, Bailey-Wilson, Joan E

Volltext

LocusZoom: regional visualization of genome-wide association scan results von Pruim, Randall J., Welch, Ryan P., Sanna, Serena, Teslovich, Tanya M., Chines, Peter S., Gliedt, Terry P., Boehnke, Michael, Abecasis, Gonçalo R., Willer, Cristen J.

Volltext

Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle von Taylor, D. Leland, Jackson, Anne U., Narisu, Narisu, Hemani, Gibran, Erdos, Michael R., Chines, Peter S., Swift, Amy, Idol, Jackie, Didion, John P., Welch, Ryan P., Kinnunen, Leena, Saramies, Jouko, Lakka, Timo A., Laakso, Markku, Tuomilehto, Jaakko, Parker, Stephen C. J., Koistinen, Heikki A., Smith, George Davey, Boehnke, Michael, Scott, Laura J., Birney, Ewan, Collins, Francis S.

Volltext

THz time-domain spectroscopic study of polyethylene-carbon black composites von Yu-Feng, SONG, Zhi-Yong, ZHU, Te, JI, Min, GE, Xi-Liang, CHEN, Qi, LIU

Volltext

Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study von Davis, James P, Huyghe, Jeroen R, Locke, Adam E, Jackson, Anne U, Sim, Xueling, Stringham, Heather M, Teslovich, Tanya M, Welch, Ryan P, Fuchsberger, Christian, Narisu, Narisu, Chines, Peter S, Kangas, Antti J, Soininen, Pasi, Ala-Korpela, Mika, Kuusisto, Johanna, Collins, Francis S, Laakso, Markku, Boehnke, Michael, Mohlke, Karen L

Volltext

Safety and tolerability of bazedoxifene in postmenopausal women with osteoporosis: results of a 5-year, randomized, placebo-controlled phase 3 trial von de Villiers, T. J, Chines, A. A, Palacios, S, Lips, P, Sawicki, A. Z, Levine, A. B, Codreanu, C, Kelepouris, N, Brown, J. P

Volltext

The genetic regulatory signature of type 2 diabetes in human skeletal muscle von Scott, Laura J., Erdos, Michael R., Huyghe, Jeroen R., Welch, Ryan P., Beck, Andrew T., Wolford, Brooke N., Chines, Peter S., Didion, John P., Narisu, Narisu, Stringham, Heather M., Taylor, D. Leland, Jackson, Anne U., Vadlamudi, Swarooparani, Bonnycastle, Lori L., Kinnunen, Leena, Saramies, Jouko, Sundvall, Jouko, Albanus, Ricardo D'Oliveira, Kiseleva, Anna, Hensley, John, Crawford, Gregory E., Jiang, Hui, Wen, Xiaoquan, Watanabe, Richard M., Lakka, Timo A., Mohlke, Karen L., Laakso, Markku, Tuomilehto, Jaakko, Koistinen, Heikki A., Boehnke, Michael, Collins, Francis S., Parker, Stephen C. J.

Volltext

Fracture risk remains reduced one year after discontinuation of risedronate von Watts, N. B., Chines, A., Olszynski, W. P., McKeever, C. D., McClung, M. R., Zhou, X., Grauer, A.

Volltext

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion von Huyghe, Jeroen R, Jackson, Anne U, Fogarty, Marie P, Buchkovich, Martin L, Stančáková, Alena, Stringham, Heather M, Sim, Xueling, Yang, Lingyao, Fuchsberger, Christian, Cederberg, Henna, Chines, Peter S, Teslovich, Tanya M, Romm, Jane M, Ling, Hua, McMullen, Ivy, Ingersoll, Roxann, Pugh, Elizabeth W, Doheny, Kimberly F, Neale, Benjamin M, Daly, Mark J, Kuusisto, Johanna, Scott, Laura J, Kang, Hyun Min, Collins, Francis S, Abecasis, Gonçalo R, Watanabe, Richard M, Boehnke, Michael, Laakso, Markku, Mohlke, Karen L

Volltext