Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer von Dawson, Sarah-Jane, Tsui, Dana W.Y, Murtaza, Muhammed, Biggs, Heather, Rueda, Oscar M, Chin, Suet-Feung, Dunning, Mark J, Gale, Davina, Forshew, Tim, Mahler-Araujo, Betania, Rajan, Sabrina, Humphray, Sean, Becq, Jennifer, Halsall, David, Wallis, Matthew, Bentley, David, Caldas, Carlos, Rosenfeld, Nitzan

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Multi-omic machine learning predictor of breast cancer therapy response von Sammut, Stephen-John, Crispin-Ortuzar, Mireia, Chin, Suet-Feung, Provenzano, Elena, Bardwell, Helen A., Ma, Wenxin, Cope, Wei, Dariush, Ali, Dawson, Sarah-Jane, Abraham, Jean E., Dunn, Janet, Hiller, Louise, Thomas, Jeremy, Cameron, David A., Bartlett, John M. S., Hayward, Larry, Pharoah, Paul D., Markowetz, Florian, Rueda, Oscar M., Earl, Helena M., Caldas, Carlos

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Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA von Murtaza, Muhammed, Dawson, Sarah-Jane, Tsui, Dana W. Y., Gale, Davina, Forshew, Tim, Piskorz, Anna M., Parkinson, Christine, Chin, Suet-Feung, Kingsbury, Zoya, Wong, Alvin S. C., Marass, Francesco, Humphray, Sean, Hadfield, James, Bentley, David, Chin, Tan Min, Brenton, James D., Caldas, Carlos, Rosenfeld, Nitzan

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Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element von Cho, Seung Woo, Xu, Jin, Sun, Ruping, Mumbach, Maxwell R., Carter, Ava C., Chen, Y. Grace, Yost, Kathryn E., Kim, Jeewon, He, Jing, Nevins, Stephanie A., Chin, Suet-Feung, Caldas, Carlos, Liu, S. John, Horlbeck, Max A., Lim, Daniel A., Weissman, Jonathan S., Curtis, Christina, Chang, Howard Y.

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Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups von Rueda, Oscar M., Sammut, Stephen-John, Seoane, Jose A., Chin, Suet-Feung, Caswell-Jin, Jennifer L., Callari, Maurizio, Batra, Rajbir, Pereira, Bernard, Bruna, Alejandra, Ali, H. Raza, Provenzano, Elena, Liu, Bin, Parisien, Michelle, Gillett, Cheryl, McKinney, Steven, Green, Andrew R., Murphy, Leigh, Purushotham, Arnie, Ellis, Ian O., Pharoah, Paul D., Rueda, Cristina, Aparicio, Samuel, Caldas, Carlos, Curtis, Christina

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The molecular landscape of Asian breast cancers reveals clinically relevant population-specific differences von Pan, Jia-Wern, Zabidi, Muhammad Mamduh Ahmad, Ng, Pei-Sze, Meng, Mei-Yee, Hasan, Siti Norhidayu, Sandey, Bethan, Sammut, Stephen-John, Yip, Cheng-Har, Rajadurai, Pathmanathan, Rueda, Oscar M., Caldas, Carlos, Chin, Suet-Feung, Teo, Soo-Hwang

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The shaping and functional consequences of the microRNA landscape in breast cancer von Dvinge, Heidi, Git, Anna, Gräf, Stefan, Salmon-Divon, Mali, Curtis, Christina, Sottoriva, Andrea, Zhao, Yongjun, Hirst, Martin, Armisen, Javier, Miska, Eric A., Chin, Suet-Feung, Provenzano, Elena, Turashvili, Gulisa, Green, Andrew, Ellis, Ian, Aparicio, Sam, Caldas, Carlos

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DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation von Batra, Rajbir Nath, Lifshitz, Aviezer, Vidakovic, Ana Tufegdzic, Chin, Suet-Feung, Sati-Batra, Ankita, Sammut, Stephen-John, Provenzano, Elena, Ali, H. Raza, Dariush, Ali, Bruna, Alejandra, Murphy, Leigh, Purushotham, Arnie, Ellis, Ian, Green, Andrew, Garrett-Bakelman, Francine E., Mason, Chris, Melnick, Ari, Aparicio, Samuel A. J. R., Rueda, Oscar M., Tanay, Amos, Caldas, Carlos

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TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance von SILWAL-PANDIT, Laxmi, MOEN VOLLAN, Hans Kristian, CALDAS, Carlos, LANGERØD, Anita, CHIN, Suet-Feung, RUEDA, Oscar M, MCKINNEY, Steven, OSAKO, Tomo, QUIGLEY, David A, KRISTENSEN, Vessela N, APARICIO, Samuel, BØRRESEN-DALE, Anne-Lise

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Copynumber: Efficient algorithms for single- and multi-track copy number segmentation von Nilsen, Gro, Liestøl, Knut, Van Loo, Peter, Moen Vollan, Hans Kristian, Eide, Marianne B, Rueda, Oscar M, Chin, Suet-Feung, Russell, Roslin, Baumbusch, Lars O, Caldas, Carlos, Børresen-Dale, Anne-Lise, Lingjaerde, Ole Christian

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Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy von Caswell-Jin, Jennifer L., McNamara, Katherine, Reiter, Johannes G., Sun, Ruping, Hu, Zheng, Ma, Zhicheng, Ding, Jie, Suarez, Carlos J., Tilk, Susanne, Raghavendra, Akshara, Forte, Victoria, Chin, Suet-Feung, Bardwell, Helen, Provenzano, Elena, Caldas, Carlos, Lang, Julie, West, Robert, Tripathy, Debu, Press, Michael F., Curtis, Christina

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αE‐catenin is a candidate tumor suppressor for the development of E‐cadherin‐expressing lobular‐type breast cancer von de Groot, Jolien S, Ratze, Max AK, van Amersfoort, Miranda, Eisemann, Tanja, Vlug, Eva J, Niklaas, Mijanou T, Chin, Suet‐Feung, Caldas, Carlos, van Diest, Paul J, Jonkers, Jos, de Rooij, Johan, Derksen, Patrick WB

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Germline APOBEC3B deletion increases somatic hypermutation in Asian breast cancer that is associated with Her2 subtype, PIK3CA mutations and immune activation von Pan, Jia‐Wern, Zabidi, Muhammad Mamduh Ahmad, Chong, Boon‐Keat, Meng, Mei‐Yee, Ng, Pei‐Sze, Hasan, Siti Norhidayu, Sandey, Bethan, Bahnu, Saira, Rajadurai, Pathmanathan, Yip, Cheng‐Har, Rueda, Oscar M., Caldas, Carlos, Chin, Suet‐Feung, Teo, Soo‐Hwang

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Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer von Ha, Gavin, Roth, Andrew, Lai, Daniel, Bashashati, Ali, Ding, Jiarui, Goya, Rodrigo, Giuliany, Ryan, Rosner, Jamie, Oloumi, Arusha, Shumansky, Karey, Chin, Suet-Feung, Turashvili, Gulisa, Hirst, Martin, Caldas, Carlos, Marra, Marco A, Aparicio, Samuel, Shah, Sohrab P

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Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer von Li, Bo, Ni Chonghaile, Triona, Fan, Yue, Madden, Stephen F, Klinger, Rut, O'Connor, Aisling E, Walsh, Louise, O'Hurley, Gillian, Mallya Udupi, Girish, Joseph, Jesuchristopher, Tarrant, Finbarr, Conroy, Emer, Gaber, Alexander, Chin, Suet-Feung, Bardwell, Helen A, Provenzano, Elena, Crown, John, Dubois, Thierry, Linn, Sabine, Jirstrom, Karin, Caldas, Carlos, O'Connor, Darran P, Gallagher, William M

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The Genomic and Immune Landscapes of Lethal Metastatic Breast Cancer von De Mattos-Arruda, Leticia, Sammut, Stephen-John, Ross, Edith M., Bashford-Rogers, Rachael, Greenstein, Erez, Markus, Havell, Morganella, Sandro, Teng, Yvonne, Maruvka, Yosef, Pereira, Bernard, Rueda, Oscar M., Chin, Suet-Feung, Contente-Cuomo, Tania, Mayor, Regina, Arias, Alexandra, Ali, H. Raza, Cope, Wei, Tiezzi, Daniel, Dariush, Aliakbar, Dias Amarante, Tauanne, Reshef, Dan, Ciriaco, Nikaoly, Martinez-Saez, Elena, Peg, Vicente, Ramon y Cajal, Santiago, Cortes, Javier, Vassiliou, George, Getz, Gad, Nik-Zainal, Serena, Murtaza, Muhammed, Friedman, Nir, Markowetz, Florian, Seoane, Joan, Caldas, Carlos

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Endogenous Purification Reveals GREB1 as a Key Estrogen Receptor Regulatory Factor von Mohammed, Hisham, D’Santos, Clive, Serandour, Aurelien A., Ali, H. Raza, Brown, Gordon D., Atkins, Alan, Rueda, Oscar M., Holmes, Kelly A., Theodorou, Vasiliki, Robinson, Jessica L.L., Zwart, Wilbert, Saadi, Amel, Ross-Innes, Caryn S., Chin, Suet-Feung, Menon, Suraj, Stingl, John, Palmieri, Carlo, Caldas, Carlos, Carroll, Jason S.

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Computational approach to discriminate human and mouse sequences in patient-derived tumour xenografts von Callari, Maurizio, Batra, Ankita Sati, Batra, Rajbir Nath, Sammut, Stephen-John, Greenwood, Wendy, Clifford, Harry, Hercus, Colin, Chin, Suet-Feung, Bruna, Alejandra, Rueda, Oscar M, Caldas, Carlos

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The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver von Hruschka, Natascha, Kalisz, Mark, Subijana, Maria, Graña-Castro, Osvaldo, Del Cano-Ochoa, Francisco, Brunet, Laia Paré, Chernukhin, Igor, Sagrera, Ana, De Reynies, Aurelien, Kloesch, Bernhard, Chin, Suet-Feung, Burgués, Octavio, Andreu, David, Bermejo, Begoña, Cejalvo, Juan Miguel, Sutton, Joe, Caldas, Carlos, Ramón-Maiques, Santiago, Carroll, Jason S., Prat, Aleix, Real, Francisco X., Martinelli, Paola

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MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype von Blenkiron, Cherie, Goldstein, Leonard D, Thorne, Natalie P, Spiteri, Inmaculada, Chin, Suet-Feung, Dunning, Mark J, Barbosa-Morais, Nuno L, Teschendorff, Andrew E, Green, Andrew R, Ellis, Ian O, Tavaré, Simon, Caldas, Carlos, Miska, Eric A

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