Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling von Huang, Hao, Hu, Jianyang, Maryam, Alishba, Huang, Qinghua, Zhang, Yuchen, Ramakrishnan, Saravanan, Li, Jingyu, Ma, Haiying, Ma, Victor W. S., Cheuk, Wah, So, Grace Y. K., Wang, Wei, Cho, William C. S., Zhang, Liang, Chan, Kui Ming, Wang, Xin, Chin, Y. Rebecca

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Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer von Chin, Y. Rebecca, Toker, Alex

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PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex von Liu, Pengda, Gan, Wenjian, Chin, Y Rebecca, Ogura, Kohei, Guo, Jianping, Zhang, Jinfang, Wang, Bin, Blenis, John, Cantley, Lewis C, Toker, Alex, Su, Bing, Wei, Wenyi

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Upregulation of AKT3 Confers Resistance to the AKT Inhibitor MK2206 in Breast Cancer von Stottrup, Casey, Tsang, Tiffany, Chin, Y Rebecca

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Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt von Zhang, Jinfang, Xu, Kai, Liu, Pengda, Geng, Yan, Wang, Bin, Gan, Wenjian, Guo, Jianping, Wu, Fei, Chin, Y. Rebecca, Berrios, Christian, Lien, Evan C., Toker, Alex, DeCaprio, James A., Sicinski, Piotr, Wei, Wenyi

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Targeting Akt3 Signaling in Triple-Negative Breast Cancer von CHIN, Y. Rebecca, YOSHIDA, Taku, MARUSYK, Andriy, BECK, Andrew H, POLYAK, Kornelia, TOKER, Alex

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TCOF1 upregulation in triple-negative breast cancer promotes stemness and tumour growth and correlates with poor prognosis von Hu, Jianyang, Lai, Yuni, Huang, Hao, Ramakrishnan, Saravanan, Pan, Yilin, Ma, Victor W. S., Cheuk, Wah, So, Grace Y. K., He, Qingling, Geoffrey Lau, C., Zhang, Liang, Cho, William C. S., Chan, Kui Ming, Wang, Xin, Rebecca Chin, Y.

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PTEN-deficient tumors depend on AKT2 for maintenance and survival von Chin, Y Rebecca, Yuan, Xin, Balk, Steven P, Toker, Alex

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Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction von Gao, Daming, Inuzuka, Hiroyuki, Tseng, Alan, Chin, Rebecca Y., Toker, Alex, Wei, Wenyi

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Acetylation-Dependent Regulation of Skp2 Function von Inuzuka, Hiroyuki, Gao, Daming, Finley, Lydia W.S., Yang, Wen, Wan, Lixin, Fukushima, Hidefumi, Chin, Y. Rebecca, Zhai, Bo, Shaik, Shavali, Lau, Alan W., Wang, Zhiwei, Gygi, Steven P., Nakayama, Keiko, Teruya-Feldstein, Julie, Toker, Alex, Haigis, Marcia C., Pandolfi, Pier Paolo, Wei, Wenyi

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mTOR Drives Its Own Activation via SCF βTrCP-Dependent Degradation of the mTOR Inhibitor DEPTOR von Gao, Daming, Inuzuka, Hiroyuki, Tan, Meng-Kwang Marcus, Fukushima, Hidefumi, Locasale, Jason W., Liu, Pengda, Wan, Lixin, Zhai, Bo, Chin, Y. Rebecca, Shaik, Shavali, Lyssiotis, Costas A., Gygi, Steven P., Toker, Alex, Cantley, Lewis C., Asara, John M., Harper, J. Wade, Wei, Wenyi

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ANLN Enhances Triple-Negative Breast Cancer Stemness Through TWIST1 and BMP2 and Promotes its Spheroid Growth von Maryam, Alishba, Chin, Y. Rebecca

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NFAT promotes carcinoma invasive migration through glypican-6 von Yiu, Gary K, Kaunisto, Aura, Chin, Y Rebecca, Toker, Alex

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Akt-ing Up on SRPK1: Oncogene or Tumor Suppressor? von Toker, Alex, Chin, Y. Rebecca

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FOSL1 is a key regulator of a super-enhancer driving TCOF1 expression in triple-negative breast cancer von He, Qingling, Hu, Jianyang, Huang, Hao, Wu, Tan, Li, Wenxiu, Ramakrishnan, Saravanan, Pan, Yilin, Chan, Kui Ming, Zhang, Liang, Yang, Mengsu, Wang, Xin, Chin, Y Rebecca

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Akt isoform-specific signaling in breast cancer: Uncovering an anti-migratory role for palladin von Chin, Y. Rebecca, Toker, Alex

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Akt3 promotes cancer stemness in triple-negative breast cancer through YB1-Snail/Slug signaling axis von Tian, Ye, Li, Jiang, Cheung, Tsz Chung, Tam, Vincent, Lau, C. Geoffrey, Wang, Xin, Chin, Y. Rebecca

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The Actin-Bundling Protein Palladin Is an Akt1-Specific Substrate that Regulates Breast Cancer Cell Migration von Chin, Y. Rebecca, Toker, Alex

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RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis von KAZEROUNIAN, Shiva, GERALD, Damien, PHUNG, Thuy L, BRAVO-NUEVO, Arturo, SHECHTER, Sharon, MCNAMARA, Stephanie, DUHADAWAY, James B, KOCHER, Olivier N, BROWN, Lawrence F, TOKER, Alex, PRENDERGAST, George C, BENJAMIN, Laura E, MINZHOU HUANG, REBECCA CHIN, Y, UDAYAKUMAR, Durga, NINGNING ZHENG, O'DONNELL, Rebekah K, PERRUZZI, Carole, MANGIANTE, Lee, POURAT, Jacob

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3-Phosphoinositide-Dependent Kinase 1 Potentiates Upstream Lesions on the Phosphatidylinositol 3-Kinase Pathway in Breast Carcinoma von MAURER, Matthew, TAO SU, CHIN, Y. Rebecca, KIM, Da-In, FERRIS, Jennifer S, GRUVBERGER-SAAL, Sofia K, LAAKSO, Mervi, XIAOMEI WANG, MEMEO, Lorenzo, ROJTMAN, Albert, MATOS, Tulio, YU, Jennifer S, SAAL, Lao H, CORDON-CARDO, Carlos, ISOLA, Jorma, TERRY, Mary Beth, TOKER, Alex, MILLS, Gordon B, ZHAO, Jean J, MURTY, Vundavalli V. V. S, HIBSHOOSH, Hanina, PARSONS, Ramon, KOUJAK, Susan, HOPKINS, Benjamin D, BARKLEY, Christina R, JIAPING WU, NANDULA, Subhadra, DUTTA, Bhaskar, YULI XIE

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