Phosphatidylinositol 3-Kinase Inhibition by Copanlisib in Relapsed or Refractory Indolent Lymphoma von Dreyling, Martin, Santoro, Armando, Mollica, Luigina, Leppä, Sirpa, Follows, George A, Lenz, Georg, Kim, Won Seog, Nagler, Arnon, Panayiotidis, Panayiotis, Demeter, Judit, Özcan, Muhit, Kosinova, Marina, Bouabdallah, Krimo, Morschhauser, Franck, Stevens, Don A, Trevarthen, David, Giurescu, Marius, Cupit, Lisa, Liu, Li, Köchert, Karl, Seidel, Henrik, Peña, Carol, Yin, Shuxin, Hiemeyer, Florian, Garcia-Vargas, Jose, Childs, Barrett H, Zinzani, Pier Luigi

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First-in-Human, Multicenter, Phase I Dose-Escalation and Expansion Study of Anti-Mesothelin Antibody-Drug Conjugate Anetumab Ravtansine in Advanced or Metastatic Solid Tumors von Hassan, Raffit, Blumenschein, Jr, George R, Moore, Kathleen N, Santin, Alessandro D, Kindler, Hedy L, Nemunaitis, John J, Seward, Shelly M, Thomas, Anish, Kim, Stella K, Rajagopalan, Prabhu, Walter, Annette O, Laurent, Dirk, Childs, Barrett H, Sarapa, Nenad, Elbi, Cem, Bendell, Johanna C

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Safety and Efficacy of Oxaliplatin and Fluoropyrimidine Regimens With or Without Bevacizumab As First-Line Treatment of Metastatic Colorectal Cancer: Results of the TREE Study von HOCHSTER, Howard S, HART, Lowell L, SCHWARTZBERG, Lee, HEDRICK, Eric, RAMANATHAN, Ramesh K, CHILDS, Barrett H, HAINSWORTH, John D, COHN, Allen L, WONG, Lucas, FEHRENBACHER, Louis, ABUBAKR, Yousif, WASIF SAIF, M

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Copanlisib population pharmacokinetics from phase I–III studies and exposure–response relationships in combination with rituximab von Morcos, Peter N., Moss, Jonathan, Austin, Rupert, Hiemeyer, Florian, Zinzani, Pier Luigi, Beckert, Vita, Mongay Soler, Lidia, Childs, Barrett H., Garmann, Dirk

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Prognostic Utility of the 21-Gene Assay in Hormone Receptor–Positive Operable Breast Cancer Compared With Classical Clinicopathologic Features von GOLDSTEIN, Lori J, GRAY, Robert, SLEDGE, George W, PEREZ, Edith A, SHULMAN, Lawrence N, MARTINO, Silvana, SPARANO, Joseph A, BADVE, Sunil, CHILDS, Barrett H, YOSHIZAWA, Carl, ROWLEY, Steve, SHAK, Steven, BAEHNER, Frederick L, RAVDIN, Peter M, DAVIDSON, Nancy E

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Use of calcium and magnesium salts to reduce oxaliplatin-related neurotoxicity von Hochster, Howard S, Grothey, Axel, Childs, Barrett H

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Estrogen- and Progesterone-Receptor Status in ECOG 2197: Comparison of Immunohistochemistry by Local and Central Laboratories and Quantitative Reverse Transcription Polymerase Chai... von BADVE, Sunil S, BAEHNER, Frederick L, MARTINO, Silvana, DAVIDSON, Nancy E, SLEDGE, George W, GOLDSTEIN, Lori J, SPARANO, Joseph A, GRAY, Robert P, CHILDS, Barrett H, MADDALA, Tara, LIU, Mei-Lan, ROWLEY, Steve C, SHAK, Steven, PEREZ, Edith D, SHULMAN, Lawrence J

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Model‐informed approach to support pediatric dosing for the pan‐PI3K inhibitor copanlisib in children and adolescents with relapsed/refractory solid tumors von Morcos, Peter N., Schlender, Jan, Burghaus, Rolf, Moss, Jonathan, Lloyd, Adam, Childs, Barrett H., Macy, Margaret E., Reid, Joel M., Chung, John, Garmann, Dirk

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Safety and antitumor activity of copanlisib in Japanese patients with relapsed/refractory indolent non-Hodgkin lymphoma: a phase Ib/II study von Fukuhara, Noriko, Maruyama, Dai, Hatake, Kiyohiko, Nagai, Hirokazu, Makita, Shinichi, Kamezaki, Kenjiro, Uchida, Toshiki, Kusumoto, Shigeru, Kuroda, Junya, Iriyama, Chisako, Yanada, Masamitsu, Tsukamoto, Norifumi, Suehiro, Youko, Minami, Hironobu, Garcia-Vargas, Jose, Childs, Barrett H., Yasuda, Masanobu, Masuda, Shigeo, Tsujino, Toshiaki, Terao, Yui, Tobinai, Kensei

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Triple negative breast cancer: unmet medical needs von Pal, Sumanta Kumar, Childs, Barrett H, Pegram, Mark

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Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials von Hong, David S, DuBois, Steven G, Kummar, Shivaani, Farago, Anna F, Albert, Catherine M, Rohrberg, Kristoffer S, van Tilburg, Cornelis M, Nagasubramanian, Ramamoorthy, Berlin, Jordan D, Federman, Noah, Mascarenhas, Leo, Geoerger, Birgit, Dowlati, Afshin, Pappo, Alberto S, Bielack, Stefan, Doz, François, McDermott, Ray, Patel, Jyoti D, Schilder, Russell J, Tahara, Makoto, Pfister, Stefan M, Witt, Olaf, Ladanyi, Marc, Rudzinski, Erin R, Nanda, Shivani, Childs, Barrett H, Laetsch, Theodore W, Hyman, David M, Drilon, Alexander

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Model‐Based Benefit/Risk Analysis for the Copanlisib Intermittent Dosing Regimen von Morcos, Peter N., Moss, Jonathan, Veasy, Josh, Hiemeyer, Florian, Childs, Barrett H., Garmann, Dirk

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Copanlisib plus rituximab versus placebo plus rituximab in patients with relapsed indolent non-Hodgkin lymphoma (CHRONOS-3): a double-blind, randomised, placebo-controlled, phase 3... von Matasar, Matthew J, Capra, Marcelo, Özcan, Muhit, Lv, Fangfang, Li, Wei, Yañez, Eduardo, Sapunarova, Katya, Lin, Tongyu, Jin, Jie, Jurczak, Wojciech, Hamed, Aryan, Wang, Ming-Chung, Baker, Ross, Bondarenko, Igor, Zhang, Qingyuan, Feng, Jifeng, Geissler, Klaus, Lazaroiu, Mihaela, Saydam, Guray, Szomor, Árpád, Bouabdallah, Krimo, Galiulin, Rinat, Uchida, Toshiki, Soler, Lidia Mongay, Cao, Anjun, Hiemeyer, Florian, Mehra, Aruna, Childs, Barrett H, Shi, Yuankai, Zinzani, Pier Luigi

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Long‐term safety and efficacy of the PI3K inhibitor copanlisib in patients with relapsed or refractory indolent lymphoma: 2‐year follow‐up of the CHRONOS‐1 study von Dreyling, Martin, Santoro, Armando, Mollica, Luigina, Leppä, Sirpa, Follows, George, Lenz, Georg, Kim, Won Seog, Nagler, Arnon, Dimou, Maria, Demeter, Judit, Özcan, Muhit, Kosinova, Marina, Bouabdallah, Krimo, Morschhauser, Franck, Stevens, Don A., Trevarthen, David, Munoz, Javier, Rodrigues, Liana, Hiemeyer, Florian, Miriyala, Ashok, Garcia‐Vargas, Jose, Childs, Barrett H., Zinzani, Pier Luigi

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PI3K inhibitors in haematological malignancies von Matasar, Matthew J, Hiemeyer, Florian, Childs, Barrett H, Zinzani, Pier Luigi

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Single-agent activity of phosphatidylinositol 3-kinase inhibition with copanlisib in patients with molecularly defined relapsed or refractory diffuse large B-cell lymphoma von Lenz, Georg, Hawkes, Eliza, Verhoef, Gregor, Haioun, Corinne, Thye Lim, Soon, Seog Heo, Dae, Ardeshna, Kirit, Chong, Geoffrey, Haaber, Jacob, Shi, Wei, Gorbatchevsky, Igor, Lippert, Susanne, Hiemeyer, Florian, Piraino, Paolo, Beckmann, Georg, Peña, Carol, Buvaylo, Viktoriya, Childs, Barrett H., Salles, Gilles

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Anetumab ravtansine versus vinorelbine in patients with relapsed, mesothelin-positive malignant pleural mesothelioma (ARCS-M): a randomised, open-label phase 2 trial von Kindler, Hedy L, Novello, Silvia, Bearz, Alessandra, Ceresoli, Giovanni L, Aerts, Joachim G J V, Spicer, James, Taylor, Paul, Nackaerts, Kristiaan, Greystoke, Alastair, Jennens, Ross, Calabrò, Luana, Burgers, Jacobus A, Santoro, Armando, Cedrés, Susana, Serwatowski, Piotr, Ponce, Santiago, Van Meerbeeck, Jan P, Nowak, Anna K, Blumenschein, Jr, George, Siegel, Jonathan M, Kasten, Linda, Köchert, Karl, Walter, Annette O, Childs, Barrett H, Elbi, Cem, Hassan, Raffit, Fennell, Dean A

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Phase II Studies with Refametinib or Refametinib plus Sorafenib in Patients with RAS -Mutated Hepatocellular Carcinoma von Lim, Ho Yeong, Merle, Philippe, Weiss, Karl Heinz, Yau, Thomas, Ross, Paul, Mazzaferro, Vincenzo, Blanc, Jean-Frédéric, Ma, Yuk Ting, Yen, Chia Jui, Kocsis, Judit, Choo, Su Pin, Sukeepaisarnjaroen, Wattana, Gérolami, René, Dufour, Jean-François, Gane, Edward J, Ryoo, Baek-Yeol, Peck-Radosavljevic, Markus, Dao, Thong, Yeo, Winnie, Lamlertthon, Wisut, Thongsawat, Satawat, Teufel, Michael, Roth, Katrin, Reis, Diego, Childs, Barrett H, Krissel, Heiko, Llovet, Josep M

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A multicenter phase II study of docetaxel, oxaliplatin, and bevacizumab in first-line therapy for unresectable locally advanced or metastatic non-squamous cell histology non-small-... von Raez, Luis E., Santos, Edgardo S., Webb, R. Timothy, Wade, James, Brito, Roger A., Karr, Melissa, Kennah, Andra, Childs, Barrett H.

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Correction: Single-agent activity of phosphatidylinositol 3-kinase inhibition with copanlisib in patients with molecularly defined relapsed or refractory diffuse large B-cell lymph... von Lenz, Georg, Hawkes, Eliza, Verhoef, Gregor, Haioun, Corinne, Thye Lim, Soon, Seog Heo, Dae, Ardeshna, Kirit, Chong, Geoffrey, Haaber, Jacob, Shi, Wei, Gorbatchevsky, Igor, Lippert, Susanne, Hiemeyer, Florian, Piraino, Paolo, Beckmann, Georg, Peña, Carol, Buvaylo, Viktoriya, Childs, Barrett H., Salles, Gilles

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