The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1 von Lin, Yiwei, Wu, Yadi, Li, Junlin, Dong, Chenfang, Ye, Xiaofeng, Chi, Young-In, Evers, B Mark, Zhou, Binhua P

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Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation von Wu, Yadi, Wang, Yu, Lin, Yiwei, Liu, Yajuan, Wang, Yifan, Jia, Jianhang, Singh, Puja, Chi, Young-In, Wang, Chi, Dong, Chenfang, Li, Wei, Tao, Min, Napier, Dana, Shi, Qiuying, Deng, Jiong, Mark Evers, B, Zhou, Binhua P.

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Identification of the PTEN-ARID4B-PI3K pathway reveals the dependency on ARID4B by PTEN-deficient prostate cancer von Wu, Ray-Chang, Young, In-Chi, Chen, Yu-Fang, Chuang, Sung-Ting, Toubaji, Antoun, Wu, Mei-Yi

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Computational modeling reveals key molecular properties and dynamic behavior of disruptor of telomeric silencing 1‐like (DOT1L) and partnering complexes involved in leukemogenesis... von Stodola, Timothy J., Chi, Young‐In, De Assuncao, Thiago M., Leverence, Elise N., Tripathi, Swarnendu, Dsouza, Nikita R., Mathison, Angela J., Volkman, Brian F., Smith, Brian C., Lomberk, Gwen, Zimmermann, Michael T., Urrutia, Raul

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Crystal structure of 3WJ core revealing divalent ion-promoted thermostability and assembly of the Phi29 hexameric motor pRNA von Zhang, Hui, Endrizzi, James A, Shu, Yi, Haque, Farzin, Sauter, Claude, Shlyakhtenko, Lyudmila S, Lyubchenko, Yuri, Guo, Peixuan, Chi, Young-In

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Computational structural genomics and clinical evidence suggest BCKDK gain‐of‐function may cause a potentially asymptomatic maple syrup urine disease phenotype von Singh, Emily, Chi, Young‐In, Kopesky, Jessica, Zimmerman, Michael, Urrutia, Raul, Basel, Donald, Schwoerer, Jessica Scott

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Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia von Dou, Liping, Yan, Fei, Pang, Jiuxia, Zheng, Dehua, Li, Dandan, Gao, Li, Wang, Lijun, Xu, Yihan, Shi, Jinlong, Wang, Qian, Zhou, Lei, Shen, Na, Singh, Puja, Wang, Lili, Li, Yonghui, Gao, Yvchi, Liu, Tao, Chen, Chongjian, Al-Kali, Aref, Litzow, Mark R., Chi, Young-In, Bode, Ann M., Liu, Chunhui, Huang, Haojie, Liu, Daihong, Marcucci, Guido, Liu, Shujun, Yu, Li

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Deep computational phenotyping of genomic variants impacting the SET domain of KMT2C reveal molecular mechanisms for their dysfunction von Jorge, Salomão Dória, Chi, Young-In, Mazaba, Jose Lizarraga, Haque, Neshatul, Wagenknecht, Jessica, Smith, Brian C, Volkman, Brian F, Mathison, Angela J, Lomberk, Gwen, Zimmermann, Michael T, Urrutia, Raul

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Molecular mechanics and dynamic simulations of well-known Kabuki syndrome-associated KDM6A variants reveal putative mechanisms of dysfunction von Chi, Young-In, Stodola, Timothy J, De Assuncao, Thiago M, Leverence, Elise N, Tripathi, Swarnendu, Dsouza, Nikita R, Mathison, Angela J, Basel, Donald G, Volkman, Brian F, Smith, Brian C, Lomberk, Gwen, Zimmermann, Michael T, Urrutia, Raul

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A novel compressive stress-based osteoarthritis-like chondrocyte system von Young, In-Chi, Chuang, Sung-Ting, Gefen, Amit, Kuo, Wei-Ting, Yang, Chun-Ting, Hsu, Chia-Hsien, Lin, Feng-Huei

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Structure of the Globular Tail of Nuclear Lamin von Dhe-Paganon, Sirano, Werner, Eric D., Chi, Young-In, Shoelson, Steven E.

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Targeting epidermal fatty acid binding protein for treatment of experimental autoimmune encephalomyelitis von Rao, Enyu, Singh, Puja, Li, Yan, Zhang, Yuwen, Chi, Young-In, Suttles, Jill, Li, Bing

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Blocking LBH expression causes replication stress and sensitizes triple-negative breast cancer cells to ATR inhibitor treatment von Garikapati, Koteswararao, Young, In-Chi, Hong, Sunhwa, Rai, Priyamvada, Jain, Chaitanya, Briegel, Karoline J.

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The G0/G1 Switch Gene 2 Regulates Adipose Lipolysis through Association with Adipose Triglyceride Lipase von Yang, Xingyuan, Lu, Xin, Lombès, Marc, Rha, Geun Bae, Chi, Young-In, Guerin, Theresa M., Smart, Eric J., Liu, Jun

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Capturing hammerhead ribozyme structures in action by modulating general base catalysis von Chi, Young-In, Martick, Monika, Lares, Monica, Kim, Rosalind, Scott, William G, Kim, Sung-Hou

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Quantitative analysis of ligand-EGFR interactions: a platform for screening targeting molecules von Kuo, Wei-Ting, Lin, Wen-Chun, Chang, Kai-Chun, Huang, Jian-Yuan, Yen, Ko-Chung, Young, In-Chi, Sun, Yu-Jun, Lin, Feng-Huei

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A multi-layered computational structural genomics approach enhances domain-specific interpretation of Kleefstra syndrome variants in EHMT1 von Chi, Young-In, Jorge, Salomão D., Jensen, Davin R., Smith, Brian C., Volkman, Brian F., Mathison, Angela J., Lomberk, Gwen, Zimmermann, Michael T., Urrutia, Raul

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Structural bioinformatics enhances the interpretation of somatic mutations in KDM6A found in human cancers von Chi, Young-In, Stodola, Timothy J., De Assuncao, Thiago M., Leverence, Elise N., Smith, Brian C., Volkman, Brian F., Mathison, Angela J., Lomberk, Gwen, Zimmermann, Michael T., Urrutia, Raul

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Homeodomain revisited : a lesson from disease-causing mutations von CHI, Young-In

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MED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells von Han, Eun Hee, Rha, Geun Bae, Chi, Young-In

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