Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis von Chew, Thean S, O'Shea, Nuala R, Sewell, Gavin W, Oehlers, Stefan H, Mulvey, Claire M, Crosier, Philip S, Godovac-Zimmermann, Jasminka, Bloom, Stuart L, Smith, Andrew M, Segal, Anthony W

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Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 [ADAMDEC1] for Intestinal Immunity and Inflammation von O’Shea, Nuala R., Chew, Thean S., Dunne, Jenny, Marnane, Rebecca, Nedjat-Shokouhi, Bahman, Smith, Philip J., Bloom, Stuart L., Smith, Andrew M., Segal, Anthony W.

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Mysterious Foreign Object on Percutaneous Endoscopic Gastrostomy Insertion von Chew, Thean S., MB, ChB, Al Ani, Fouad S.S., MB, ChB, Hafeez, Irfan, MB, BS

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Asymptomatic bronchial aspiration and retention of a capsule endoscope von Leeds, John S., MRCP, Chew, Thean S., MRCP, Sidhu, Reena, MRCP, Elliot, Charles A., MRCP, Sanders, David S., FRCP, MD, McAlindon, Mark E., FRCP, MD

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Disruption of macrophage pro‐inflammatory cytokine release in Crohn's disease is associated with reduced optineurin expression in a subset of patients von Smith, Andrew M., Sewell, Gavin W., Levine, Adam P., Chew, Thean S., Dunne, Jenny, O'Shea, Nuala R., Smith, Philip J., Harrison, Penelope J., Macdonald, Carol M., Bloom, Stuart L., Segal, Anthony W.

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Optineurin deficiency contributes to impaired cytokine secretion and neutrophil recruitment in bacteria driven colitis von Chew, Thean S., O'Shea, Nuala R., Sewell, Gavin W., Oehlers, Stefan H., Mulvey, Claire M., Crosier, Philip S., Godovac-Zimmermann, Jasminka, Bloom, Stuart L., Smith, Andrew M., Segal, Anthony W.

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P139 Microscopic colitis: lost opportunity for diagnosis and treatment results in hospital admissions von Raju, Suneil A, Chew, Thean S, Sanders, David S

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Is there a role for routine duodenal biopsy in diagnosing giardiasis in a European population? von Chew, Thean S., Hopper, Andrew D., Sanders, David S.

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P240 Coeliac disease and microscopic colitis: the first study assessing prognosis and risk of hospital admission von Raju, Sunny, Kaur, Kamaldeep E, Rawcliffe, Megan E, Chew, Thean S, Sanders, David S

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Percutaneous endoscopic gastrostomy insertion: are we getting better? von Chew, Thean S, Sumaya, Wael, Grimley, Charles EF

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P103 Long term treatment with tofacitinib for ulcerative colitis refractory to anti-tumour necrosis factor agents: real-world experience from a single centre von Atrash, Malik Satea El, Ahmed, Omar, Hamdy, Mohamed Yehia, Brooks, Alenka J, Chew, Thean S, Phillips, Anne, Rej, Anupam, Robinson, Kerry, Lobo, Alan J, Hale, Melissa F

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OWE-01 The effect of infliximab dose escalation in inflammatory bowel disease patients with antibodies to infliximab von Tun, Gloria SZ, Marshall, Laura, Thompson, Laura, Campbell, Rebecca, Hale, Melissa F, Chew, Thean S, Brooks, Alenka J, Robinson, Kerry, Lobo, Alan J

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PWE-065 Antibodies-to-infliximab post induction can help identify inflammatory bowel disease patients at risk of treatment failure von Tun, Gloria Shwe Zin, Marshall, Sister Laura, Robinson, Sister Kerry, Wright, Sister Alison, Brookes, Dr Alenka, Chew, Thean S, Hale, Melissa, Lobo, Alan J

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Disruption of macrophage pro‐inflammatory cytokine release in C rohn's disease is associated with reduced optineurin expression in a subset of patients von Smith, Andrew M., Sewell, Gavin W., Levine, Adam P., Chew, Thean S., Dunne, Jenny, O'Shea, Nuala R., Smith, Philip J., Harrison, Penelope J., Macdonald, Carol M., Bloom, Stuart L., Segal, Anthony W.

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High prevalence of antibodies to infliximab and their relation to clinical outcomes in inflammatory bowel disease patients von Tun, Gloria S. Z., Downey, Robert, Robinson, Kerry, Wright, Alison, Marshall, Laura, Emsell, Kristina, Swallow, Kirsty, Wild, Graeme, Brooks, Alenka J., Chew, Thean S., Hale, Melissa F., Sargur, Ravishankar, Lobo, Alan J.

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Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 ADAMDEC1 for Intestinal Immunity and Inflammation von O'Shea, Nuala R, Chew, Thean S, Dunne, Jenny, Marnane, Rebecca, Nedjat-Shokouhi, Bahman, Smith, Philip J, Bloom, Stuart L, Smith, Andrew M, Segal, Anthony W

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Small Bowel Bacterial Overgrowth in Symptomatic Older People: Is Empirical Antibiotic Treatment Justified? von Elphick, David A., Chew, Thean S., Higham, Susan, Bird, Nigel, Ahmed, Amjad K., Ahmad, Salina, Sanders, David

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Prevalence of Healthcare-Associated Infections and Antimicrobial Use Among Adult Inpatients in Singapore Acute-Care Hospitals: Results From the First National Point Prevalence Surv... von Cai, Yiying, Venkatachalam, Indumathi, Tee, Nancy W., Tan, Thean Yen, Kurup, Asok, Wong, Sin Yew, Low, Chian Yong, Wang, Yang, Lee, Winnie, Liew, Yi Xin, Ang, Brenda, Lye, David C., Chow, Angela, Ling, Moi Lin, Oh, Helen M., Cuvin, Cassandra A., Ooi, Say Tat, Pada, Surinder K., Lim, Chong Hee, Tan, Jack Wei Chieh, Chew, Kean Lee, Nguyen, Van Hai, Fisher, Dale A., Goossens, Herman, Kwa, Andrea L., Tambyah, Paul A., Hsu, Li Yang, Marimuthu, Kalisvar

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In search of germline variants associated with metastasis risk in sporadic colorectal carcinomas: towards personalized therapeutic decision von Thean, L.F., Lo, M., Chew, M.H., Tang, C.L., Cheah, P.Y.

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Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patient... von Thean, Lai Fun, Wong, Yu Hui, Lo, Michelle, Loi, Carol, Chew, Min Hoe, Tang, Choong Leong, Cheah, Peh Yean

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