A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy von Maruani, Antoine, Smith, Mark E.B., Miranda, Enrique, Chester, Kerry A., Chudasama, Vijay, Caddick, Stephen

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The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respirator... von Thistlethwaite, Fiona C., Gilham, David E., Guest, Ryan D., Rothwell, Dominic G., Pillai, Manon, Burt, Deborah J., Byatte, Andrea J., Kirillova, Natalia, Valle, Juan W., Sharma, Surinder K., Chester, Kerry A., Westwood, Nigel B., Halford, Sarah E. R., Nabarro, Stephen, Wan, Susan, Austin, Eric, Hawkins, Robert E.

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Stromal features are predictive of disease mortality in oral cancer patients von Marsh, Daniel, Suchak, Krishna, Moutasim, Karwan A, Vallath, Sabarinath, Hopper, Colin, Jerjes, Waseem, Upile, Tahwinder, Kalavrezos, Nicholas, Violette, Shelia M, Weinreb, Paul H, Chester, Kerry A, Chana, Jagdeep S, Marshall, John F, Hart, Ian R, Hackshaw, Allan K, Piper, Kim, Thomas, Gareth J

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A Simple and Robust Single-Step Method for CAR-Vδ1 γδT Cell Expansion and Transduction for Cancer Immunotherapy von Ferry, Gabrielle M., Agbuduwe, Charles, Forrester, Megan, Dunlop, Sophie, Chester, Kerry, Fisher, Jonathan, Anderson, John, Barisa, Marta

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Tuning the Hydrolytic Stability of Next Generation Maleimide Cross-Linkers Enables Access to Albumin-Antibody Fragment Conjugates and tri-scFvs von Forte, Nafsika, Livanos, Maria, Miranda, Enrique, Morais, Maurício, Yang, Xiaoping, Rajkumar, Vineeth S, Chester, Kerry A, Chudasama, Vijay, Baker, James R

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Next generation maleimides enable the controlled assembly of antibody-drug conjugates via native disulfide bond bridging von Schumacher, Felix F, Nunes, João P M, Maruani, Antoine, Chudasama, Vijay, Smith, Mark E B, Chester, Kerry A, Baker, James R, Caddick, Stephen

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Anti-CD45 PBD-based antibody-drug conjugates are effective targeted conditioning agents for gene therapy and stem cell transplant von Yeung, Jenny, Liao, Aiyin, Shaw, Matthew, Silva, Soraia, Vetharoy, Winston, Rico, Diego Leon, Kirby, Ian, Zammarchi, Francesca, Havenith, Karin, de Haan, Lolke, van Berkel, Patrick H., Sebire, Neil, Ogunbiyi, Olumide K., Booth, Claire, Gaspar, H. Bobby, Thrasher, Adrian J., Chester, Kerry A., Amrolia, Persis J.

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Potential of Magnetic Hyperthermia to Stimulate Localized Immune Activation von Carter, Thomas J., Agliardi, Giulia, Lin, Fang‐Yu, Ellis, Matthew, Jones, Clare, Robson, Mathew, Richard‐Londt, Angela, Southern, Paul, Lythgoe, Mark, Zaw Thin, May, Ryzhov, Vyacheslav, Rosales, Rafael T. M., Gruettner, Cordula, Abdollah, Maha R. A., Pedley, R. Barbara, Pankhurst, Quentin A., Kalber, Tammy L., Brandner, Sebastian, Quezada, Sergio, Mulholland, Paul, Shevtsov, Maxim, Chester, Kerry

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Granzyme B Functionalized Nanoparticles Targeting Membrane Hsp70‐Positive Tumors for Multimodal Cancer Theranostics von Shevtsov, Maxim, Stangl, Stefan, Nikolaev, Boris, Yakovleva, Ludmila, Marchenko, Yaroslav, Tagaeva, Ruslana, Sievert, Wolfgang, Pitkin, Emil, Mazur, Anton, Tolstoy, Peter, Galibin, Oleg, Ryzhov, Vyacheslav, Steiger, Katja, Smirnov, Oleg, Khachatryan, William, Chester, Kerry, Multhoff, Gabriele

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Acid-cleavable thiomaleamic acid linker for homogeneous antibody-drug conjugation von Castañeda, Lourdes, Maruani, Antoine, Schumacher, Felix F, Miranda, Enrique, Chudasama, Vijay, Chester, Kerry A, Baker, James R, Smith, Mark E B, Caddick, Stephen

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A vector-encoded bispecific killer engager to harness virus-activated NK cells as anti-tumor effectors von Floerchinger, Alessia, Klein, Jessica E., Finkbeiner, Maximiliane S. C., Schäfer, Theresa E., Fuchs, Gwendolin, Doerner, Johannes, Zirngibl, Hubert, Ackermann, Maximilian, Kvasnicka, Hans M., Chester, Kerry A., Jäger, Dirk, Ball, Claudia R., Ungerechts, Guy, Engeland, Christine E.

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Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance von Chakravarthy, Ankur, Reddin, Ian, Henderson, Stephen, Dong, Cindy, Kirkwood, Nerissa, Jeyakumar, Maxmilan, Rodriguez, Daniela Rothschild, Martinez, Natalia Gonzalez, McDermott, Jacqueline, Su, Xiaoping, Egawa, Nagayasau, Fjeldbo, Christina S., Skingen, Vilde Eide, Lyng, Heidi, Halle, Mari Kyllesø, Krakstad, Camilla, Soleiman, Afschin, Sprung, Susanne, Lechner, Matt, Ellis, Peter J. I., Wass, Mark, Michaelis, Martin, Fiegl, Heidi, Salvesen, Helga, Thomas, Gareth J., Doorbar, John, Chester, Kerry, Feber, Andrew, Fenton, Tim R.

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Homogeneous Bispecifics by Disulfide Bridging von Hull, Elizabeth A, Livanos, Maria, Miranda, Enrique, Smith, Mark E. B, Chester, Kerry A, Baker, James R

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scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal cancer cells von Silveira, Maria José, Martins, Cláudia, Cruz, Tânia, Castro, Flávia, Amorim-Costa, Ângela, Chester, Kerry, Oliveira, Maria José, Sarmento, Bruno

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Aryloxymaleimides for cysteine modification, disulfide bridging and the dual functionalization of disulfide bonds von Marculescu, Cristina, Kossen, Hanno, Morgan, Rachel E, Mayer, Patrick, Fletcher, Sally A, Tolner, Berend, Chester, Kerry A, Jones, Lyn H, Baker, James R

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Preclinical evaluation of a novel CEA‐targeting near‐infrared fluorescent tracer delineating colorectal and pancreatic tumors von Boonstra, Martin C., Tolner, Berend, Schaafsma, Boudewijn E., Boogerd, Leonora S.F., Prevoo, Hendrica A.J.M, Bhavsar, Guarav, Kuppen, Peter J.K., Sier, Cornelis F.M., Bonsing, Bert A., Frangioni, John V., van de Velde, Cornelis J.H., Chester, Kerry A., Vahrmeijer, Alexander L.

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Fucoidan Prolongs the Circulation Time of Dextran-Coated Iron Oxide Nanoparticles von Abdollah, Maha R. A, Carter, Thomas J, Jones, Clare, Kalber, Tammy L, Rajkumar, Vineeth, Tolner, Berend, Gruettner, Cordula, Zaw-Thin, May, Baguña Torres, Julia, Ellis, Matthew, Robson, Mathew, Pedley, R. Barbara, Mulholland, Paul, T. M. de Rosales, Rafael, Chester, Kerry Ann

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Targeted photodynamic therapy with multiply‐loaded recombinant antibody fragments von Bhatti, Manpreet, Yahioglu, Gokhan, Milgrom, Lionel R., Garcia‐Maya, Mitla, Chester, Kerry A., Deonarain, Mahendra P.

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Homogeneous antibody fragment conjugation by disulfide bridging introduces ‘spinostics’ von Schumacher, Felix F., Sanchania, Vishal A., Tolner, Berend, Wright, Zoë V. F., Ryan, Chris P., Smith, Mark E. B., Ward, John M., Caddick, Stephen, Kay, Christopher W. M., Aeppli, Gabriel, Chester, Kerry A., Baker, James R.

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A novel anti-B7-H3 chimeric antigen receptor from a single-chain antibody library for immunotherapy of solid cancers von Birley, Kathleen, Leboreiro-Babe, Clara, Rota, Enrique Miranda, Buschhaus, Magdalena, Gavriil, Artemis, Vitali, Alice, Alonso-Ferrero, Maria, Hopwood, Lee, Parienti, Lara, Ferry, Gabrielle, Flutter, Barry, Himoudi, Nourredine, Chester, Kerry, Anderson, John

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