Metal-catalysed radical cyclisations leading to N-heterocycles: new approaches to gabapentin and pulchellalactam von Bryans, Justin S, Chessum, Nicola E.A, Huther, Nathalie, Parsons, Andrew F, Ghelfi, Franco

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The synthesis of functionalised β- and γ-lactams by cyclisation of enamides using copper(I) or ruthenium(II) von Bryans, Justin S, Chessum, Nicola E.A, Parsons, Andrew F, Ghelfi, Franco

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Determination of Ligand-Binding Affinity (Kd) Using Transverse Relaxation Rate (R2) in the Ligand-Observed 1H NMR Experiment and Applications to Fragment-Based Drug Discovery von Liu, M, Mirza, A, McAndrew, PC, Thapaliya, A, Pierrat, OA, Stubbs, M, Hahner, T, Chessum, NEA, Innocenti, P, Caldwell, J, Cheeseman, MD, Bellenie, BR, van Montfort, RLM, Newton, GK, Burke, R, Collins, I, Hoelder, S

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HSF1 Pathway Inhibitor Clinical Candidate (CCT361814/NXP800) Developed from a Phenotypic Screen as a Potential Treatment for Refractory Ovarian Cancer and Other Malignancies von Pasqua, AE, Sharp, SY, Chessum, NEA, Hayes, A, Pellegrino, L, Tucker, MJ, Miah, A, Wilding, B, Evans, LE, Rye, CS, Mok, NY, Liu, M, Henley, AT, Gowan, S, De Billy, E, te Poele, R, Powers, M, Eccles, SA, Clarke, PA, Raynaud, FI, Workman, P, Jones, K, Cheeseman, MD

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