Biomarkers of coagulation, endothelial function, and fibrinolysis in critically ill patients with COVID‐19: A single‐center prospective longitudinal study von Juneja, Ganeem K., Castelo, Matthew, Yeh, Calvin H., Cerroni, Samantha E., Hansen, Bettina E., Chessum, James E., Abraham, Joel, Cani, Erblin, Dwivedi, Dhruva J., Fraser, Douglas D., Slessarev, Marat, Martin, Claudio, McGilvray, Scott, Gross, Peter L., Liaw, Patricia C., Weitz, Jeffrey I., Kim, Paul Y.

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Lightning protection design and testing of an all composite wet wing for the Egrett von Burrows, B. J. C., Haigh, S. J., Chessum, C., Dunkley, V. P.

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Synthesis and in vivo evaluation of bicyclic gababutins von Blakemore, David C., Bryans, Justin S., Carnell, Pauline, Carr, Christopher L., Chessum, Nicola E.A., Field, Mark J., Kinsella, Natasha, Osborne, Simon A., Warren, Andrew N., Williams, Sophie C.

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Synthesis and in vivo evaluation of 3-substituted gababutins von Blakemore, David C., Bryans, Justin S., Carnell, Pauline, Chessum, Nicola E.A., Field, Mark J., Kinsella, Natasha, Kinsora, Jack K., Osborne, Simon A., Williams, Sophie C.

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Helios is a key transcriptional regulator of outer hair cell maturation von Chessum, Lauren, Matern, Maggie S., Kelly, Michael C., Johnson, Stuart L., Ogawa, Yoko, Milon, Beatrice, McMurray, Mark, Driver, Elizabeth C., Parker, Andrew, Song, Yang, Codner, Gemma, Esapa, Christopher T., Prescott, Jack, Trent, Graham, Wells, Sara, Dragich, Abigail K., Frolenkov, Gregory I., Kelley, Matthew W., Marcotti, Walter, Brown, Steve D. M., Elkon, Ran, Bowl, Michael R., Hertzano, Ronna

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Ikzf2/helios is a key transcriptional regulator of outer hair cell maturation von Chessum, Lauren, Matern, Maggie S, Kelly, Michael C, Johnson, Stuart L, Ogawa, Yoko, Milon, Beatrice, McMurray, Mark, Driver, Elizabeth C, Parker, Andrew, Song, Yang, Codner, Gemma, Esapa, Christopher T, Prescott, Jack, Trent, Graham, Wells, Sara, Dragich, Abigail K, Frolenkov, Gregory I., Kelley, Matthew W, Marcotti, Walter, Brown, Steve DM, Elkon, Ran, Bowl, Michael R, Hertzano, Ronna

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Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant von Zhang, Y, Dean, C, Chessum, L, Dao, N, Stewart, M, Taylor, M, Cookson, WO, Moffatt, MF

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Manipulation of Dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma von Zhang, Y, Poobalasingam, T, Yates, LL, Walker, SA, Taylor, MS, Chessum, L, Harrison, J, Tsaprouni, L, Adcock, IM, Lloyd, CM, Cookson, WO, Moffatt, MF, Dean, CH

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Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung von Yates, LL, Schnatwinkel, C, Hazelwood, L, Chessum, L, Paudyal, A, Hilton, H, Romero, MR, Wilde, J, Bogani, D, Sanderson, J, Formstone, C, Murdoch, JN, Niswander, LA, Greenfield, A, Dean, CH

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Determination of Ligand-Binding Affinity (Kd) Using Transverse Relaxation Rate (R2) in the Ligand-Observed 1H NMR Experiment and Applications to Fragment-Based Drug Discovery von Liu, M, Mirza, A, McAndrew, PC, Thapaliya, A, Pierrat, OA, Stubbs, M, Hahner, T, Chessum, NEA, Innocenti, P, Caldwell, J, Cheeseman, MD, Bellenie, BR, van Montfort, RLM, Newton, GK, Burke, R, Collins, I, Hoelder, S

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HSF1 Pathway Inhibitor Clinical Candidate (CCT361814/NXP800) Developed from a Phenotypic Screen as a Potential Treatment for Refractory Ovarian Cancer and Other Malignancies von Pasqua, AE, Sharp, SY, Chessum, NEA, Hayes, A, Pellegrino, L, Tucker, MJ, Miah, A, Wilding, B, Evans, LE, Rye, CS, Mok, NY, Liu, M, Henley, AT, Gowan, S, De Billy, E, te Poele, R, Powers, M, Eccles, SA, Clarke, PA, Raynaud, FI, Workman, P, Jones, K, Cheeseman, MD

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Clarin‐2 is essential for hearing by maintaining stereocilia integrity and function von Dunbar, L.A, Patni, P, Aguilar, C, Mburu, P, Corns, L, Wells, H.R.R, Delmaghani, S, Parker, A, Johnson, S, Williams, D, Esapa, C.T, Simon, M.M, Chessum, L, Newton, S, Dorning, J, Jeyarajan, P, Morse, S, Lelli, A, Codner, G.F, Peineau, T, Gopal, S.R, Alagramam, K.N, Hertzano, R, Dulon, D, Wells, S, Williams, F.M, Petit, C, Dawson, S.J, Brown, S.D.M, Marcotti, W, El‐Amraoui, A, Bowl, M.R

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Helios is a key transcriptional regulator of outer hair cell maturation von Chessum, L, Matern, MS, Kelly, MC, Johnson, SL, Ogawa, Y, Milon, B, McMurray, M, Driver, EC, Parker, A, Song, Y, Codner, G, Esapa, CT, Prescott, J, Trent, G, Wells, S, Dragich, AK, Frolenkov, GI, Kelley, MW, Marcotti, W, Brown, SDM, Elkon, R, Bowl, MR, Hertzano, R

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Clarin-2 is essential for hearing by maintaining stereocilia integrity and function von Dunbar, LA, Patni, P, Aguilar, C, Mburu, P, Corns, L, Wells, HR, Delmaghani, S, Parker, A, Johnson, S, Williams, D, Esapa, CT, Simon, MM, Chessum, L, Newton, S, Dorning, J, Jeyarajan, P, Morse, S, Lelli, A, Codner, GF, Peineau, T, Gopal, SR, Alagramam, KN, Hertzano, R, Dulon, D, Wells, S, Williams, FM, Petit, C, Dawson, SJ, Brown, SD, Marcotti, W, El-Amraoui, A, Bowl, MR

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Correction of the auditory phenotype in C57BL/6N mice via CRISPR/Cas9-mediated homology directed repair von Mianne, J, Chessum, L, Kumar, S, Aguilar, C, Codner, G, Hutchison, M, Parker, A, Mallon, A-M, Wells, S, Simon, MM, Teboul, L, Brown, SDM, Bowl, MR

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Absence of Neuroplastin-65 Affects Synaptogenesis in Mouse Inner Hair Cells and Causes Profound Hearing Loss von Carrott, L, Bowl, MR, Aguilar, C, Johnson, SL, Chessum, L, West, M, Morse, S, Dorning, J, Smart, E, Hardisty-Hughes, R, Ball, G, Parker, A, Barnard, AR, MacLaren, RE, Wells, S, Marcotti, W, Brown, SDM

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Novel gene function revealed by mouse mutagenesis screens for models of age-related disease von Potter, PK, Bowl, MR, Jeyarajan, P, Wisby, L, Blease, A, Goldsworthy, ME, Simon, MM, Greenaway, S, Michel, V, Barnard, A, Aguilar, C, Agnew, T, Banks, G, Blake, A, Chessum, L, Dorning, J, Falcone, S, Goosey, L, Harris, S, Haynes, A, Heise, I, Hillier, R, Hough, T, Hoslin, A, Hutchison, M, King, R, Kumar, S, Lad, HV, Law, G, MacLaren, RE, Morse, S, Nicol, T, Parker, A, Pickford, K, Sethi, S, Starbuck, B, Stelma, F, Cheeseman, M, Cross, SH, Foster, RG, Jackson, IJ, Peirson, SN, Thakker, RV, Vincent, T, Scudamore, C, Wells, S, El-Amraoui, A, Petit, C, Acevedo-Arozena, A, Nolan, PM, Cox, R, Mallon, A-M, Brown, SDM

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ChemInform Abstract: Synthesis and in vivo Evaluation of 3-Substituted Gababutins von Blakemore, David C., Bryans, Justin S., Carnell, Pauline, Chessum, Nicola E. A., Field, Mark J., Kinsella, Natasha, Kinsora, Jack K., Osborne, Simon A., Williams, Sophie C.

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