Potential impact of family history–based screening guidelines on the detection of early‐onset colorectal cancer von Gupta, Samir, Bharti, Balambal, Ahnen, Dennis J., Buchanan, Daniel D., Cheng, Iona C., Cotterchio, Michelle, Figueiredo, Jane C., Gallinger, Steven J., Haile, Robert W., Jenkins, Mark A., Lindor, Noralane M., Macrae, Finlay A., Le Marchand, Loïc, Newcomb, Polly A., Thibodeau, Stephen N., Win, Aung Ko, Martinez, Maria Elena

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Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals von Chen, Hongjie, Majumdar, Arunabha, Wang, Lu, Kar, Siddhartha, Brown, Kevin M., Feng, Helian, Turman, Constance, Dennis, Joe, Easton, Douglas, Michailidou, Kyriaki, Simard, Jacques, Bishop, Timothy, Cheng, Iona C., Huyghe, Jeroen R., Schmit, Stephanie L., O’Mara, Tracy A., Spurdle, Amanda B., Gharahkhani, Puya, Schumacher, Johannes, Jankowski, Janusz, Gockel, Ines, Bondy, Melissa L., Houlston, Richard S., Jenkins, Robert B., Melin, Beatrice, Lesseur, Corina, Ness, Andy R., Diergaarde, Brenda, Olshan, Andrew F., Amos, Christopher I., Christiani, David C., Landi, Maria T., McKay, James D., Brossard, Myriam, Iles, Mark M., Law, Matthew H., MacGregor, Stuart, Beesley, Jonathan, Jones, Michelle R., Tyrer, Jonathan, Winham, Stacey J., Klein, Alison P., Petersen, Gloria, Li, Donghui, Wolpin, Brian M., Eeles, Rosalind A., Haiman, Christopher A., Kote-Jarai, Zsofia, Schumacher, Fredrick R., Brennan, Paul, Chanock, Stephen J., Gaborieau, Valerie, Purdue, Mark P., Pharoah, Paul, Hung, Rayjean J., Amundadottir, Laufey T., Kraft, Peter, Pasaniuc, Bogdan, Lindström, Sara

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Abstract 3436: Exposure to long-term traffic-related air pollutants, NO2 and NOX, and breast cancer incidence: The Multiethnic Cohort von Cheng, Iona C., Yang, Juan, Tseng, Chiuchen, Lee, Leo, Wu, Jun, Stram, Daniel, Monroe, Kristine, Le Marchand, Loic, Gomez, Scarlett Lin, Whittemore, Alice, Shariff-Marco, Salma, Ritz, Beate, Wu, Anna

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US lung cancer trends by histologic type von Patel, Manali I., Cheng, Iona, Gomez, Scarlett Lin

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Potential impact of family history based screening guidelines on early onset colorectal cancer detection von Gupta, Samir, Bharti, Balambal, Ahnen, Dennis J., Buchanan, Daniel D., Cheng, Iona C., Cotterchio, Michelle, Figueiredo, Jane C., Gallinger, Steven J., Haile, Robert W., Jenkins, Mark A., Lindor, Noralane M., Macrae, Finlay, Le Marchand, Loïc, Newcomb, Polly A., Thibodeau, Stephen N., Win, Aung Ko, Martinez, Maria Elena

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Abstract 945: Genetic association study of the mitochondrial genome and colorectal cancer risk: The Multiethnic Cohort von Cheng, Iona C., Caberto, Christian, Beckman, Kenneth, Lum-Jones, Annette, Haiman, Christopher, Marchand, Loic L., Stram, Daniel, Saxena, Richa

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Abstract 2832: Genetic variation in TGFB1 , TGFBR1 , TGFBR2 , and prostate cancer risk and recurrence von Cheng, Iona C., Plummer, Sarah, Mefford, Joel, Neslund-Dudas, Christine, Casey, Graham, Rybicki, Benjamin, Witte, John

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Abstract 884: Pleiotropic effects on lung cancer of genetic susceptibility variants identified for other malignancies: The multiethnic cohort von Cheng, Iona C., Caberto, Christian, Wilkens, Lynne R., Schumacher, Fredrick R., Kolonel, Laurence N., Henderson, Brian E., Stram, Daniel O., Haiman, Christopher A., Marchand, Loic Le

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Abstract 3760: Associations of risk variants for 20 different malignancies with colorectal cancer in a multiethnic population von Cheng, Iona C., Caberto, Christian, Wilkens, Lynne R., Schumacher, Fredrick R., Kolonel, Laurence N., Henderson, Brian E., Stram, Daniel O., Haiman, Christopher A., Marchand, Loic Le

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Abstract B32: Evaluating genetic risk for prostate cancer among Japanese Americans and Latinos: The Multiethnic Cohort Study von Cheng, Iona C., Stram, Daniel O., Kolonel, Laurence N., Henderson, Brian E., Marchand, Loïc Le, Haiman, Christopher A., Chen, Gary K., He, Jing, Wan, Peggy, Sheng, Xin, Pooler, Loreall C., Wilkens, Lynne R., Monroe, Kristine R.

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Abstract 1662: Pleiotropic effects on lung cancer of genetic susceptibility variants identified for other malignancies: The Population Architecture using Genomics and Epidemiology... von Fesinmeyer, Megan D., Lin, Yi, Biggs, Mary Lou, Bush, William S., Butler, Anne M., Buyske, Steven, Caberto, Christian P., Carty, Cara L., Cote, Michele L., Crawford, Dana C., Dumitrescu, Logan, Fowke, Jay H., Giovino, Gary A., Haiman, Christopher A., Heiss, Gerardo, Hindorff, Lucia A., Kooperberg, Charles, Love, Shelly-Ann, Matise, Tara C., North, Kari E., Park, Sungshim Lani, Peters, Ulrike, Wilkens, Lynne R., Wise, Anastasia L., Marchand, Loic Le, Cheng, Iona C.

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Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals von Chen, Hongjie, Majumdar, Arunabha, Wang, Lu, Kar, Siddhartha, Brown, Kevin M, Feng, Helian, Turman, Constance, Dennis, Joe, Easton, Douglas, Michailidou, Kyriaki, Simard, Jacques, Bishop, Timothy, Cheng, Iona C, Huyghe, Jeroen R, Schmit, Stephanie L, O'Mara, Tracy A, Spurdle, Amanda B, Gharahkhani, Puya, Schumacher, Johannes, Jankowski, Janusz, Gocke, Ines, Bondy, Melissa L, Houlston, Richard S, Jenkins, Robert B, Melin, Beatrice, Lesseur, Corina, Ness, Andy R, Diergaarde, Brenda, Olshan, Andrew F, Amos, Christopher I, Christiani, David C, Landi, Maria T, McKay, James D, Brossard, Myriam, Iles, Mark M, Law, Matthew H, MacGregor, Stuart, Beesley, Jonathan, Jones, Michelle R, Tyrer, Jonathan, Winham, Stacey J, Klein, Alison P, Petersen, Gloria, Li, Donghui, Wolpin, Brian M, Eeles, Rosalind A, Haiman, Christopher A, Kote-Jarai, Zsofia, Schumacher, Fredrick R, Brennan, Paul, Chanock, Stephen J, Gaborieau, Valerie, Purdue, Mark P, Pharoah, Paul, Hung, Rayjean J, Amundadottir, Laufey T, Kraft, Peter, Pasaniuc, Bogdan, Lindström, Sara

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Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations von Dai, Juncheng, Lv, Jun, Zhu, Meng, Wang, Yuzhuo, Qin, Na, Ma, Hongxia, He, Yong-Qiao, Zhang, Ruoxin, Tan, Wen, Fan, Jingyi, Wang, Tianpei, Zheng, Hong, Sun, Qi, Wang, Lijuan, Huang, Mingtao, Ge, Zijun, Yu, Canqing, Guo, Yu, Wang, Tong-Min, Wang, Jie, Xu, Lin, Wu, Weibing, Chen, Liang, Bian, Zheng, Walters, Robin, Millwood, Iona Y, Li, Xi-Zhao, Wang, Xin, Hung, Rayjean J, Christiani, David C, Chen, Haiquan, Wang, Mengyun, Wang, Cheng, Jiang, Yue, Chen, Kexin, Chen, Zhengming, Jin, Guangfu, Wu, Tangchun, Lin, Dongxin, Hu, Zhibin, Amos, Christopher I, Wu, Chen, Wei, Qingyi, Jia, Wei-Hua, Li, Liming, Shen, Hongbing

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Risk Stratification for Second Primary Lung Cancer von Han, Summer S, Rivera, Gabriel A, Tammemägi, Martin C, Plevritis, Sylvia K, Gomez, Scarlett L, Cheng, Iona, Wakelee, Heather A

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Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants von Kampmann, Beate, Madhi, Shabir A., Munjal, Iona, Simões, Eric A.F., Pahud, Barbara A., Llapur, Conrado, Baker, Jeffrey, Pérez Marc, Gonzalo, Radley, David, Shittu, Emma, Glanternik, Julia, Snaggs, Hasra, Baber, James, Zachariah, Philip, Barnabas, Shaun L., Fausett, Merlin, Adam, Tyler, Perreras, Nicole, Van Houten, Marlies A., Kantele, Anu, Huang, Li-Min, Bont, Louis J., Otsuki, Takeo, Vargas, Sergio L., Gullam, Joanna, Tapiero, Bruce, Stein, Renato T., Polack, Fernando P., Zar, Heather J., Staerke, Nina B., Duron Padilla, María, Richmond, Peter C., Koury, Kenneth, Schneider, Katherine, Kalinina, Elena V., Cooper, David, Jansen, Kathrin U., Anderson, Annaliesa S., Swanson, Kena A., Gruber, William C., Gurtman, Alejandra

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Genetic analyses of diverse populations improves discovery for complex traits von Wojcik, Genevieve L., Graff, Mariaelisa, Nishimura, Katherine K., Tao, Ran, Haessler, Jeffrey, Gignoux, Christopher R., Highland, Heather M., Patel, Yesha M., Sorokin, Elena P., Avery, Christy L., Belbin, Gillian M., Bien, Stephanie A., Cheng, Iona, Cullina, Sinead, Hodonsky, Chani J., Hu, Yao, Huckins, Laura M., Jeff, Janina, Justice, Anne E., Kocarnik, Jonathan M., Lim, Unhee, Lin, Bridget M., Lu, Yingchang, Nelson, Sarah C., Park, Sung-Shim L., Poisner, Hannah, Preuss, Michael H., Richard, Melissa A., Schurmann, Claudia, Setiawan, Veronica W., Sockell, Alexandra, Vahi, Karan, Verbanck, Marie, Vishnu, Abhishek, Walker, Ryan W., Young, Kristin L., Zubair, Niha, Acuña-Alonso, Victor, Ambite, Jose Luis, Barnes, Kathleen C., Boerwinkle, Eric, Bottinger, Erwin P., Bustamante, Carlos D., Caberto, Christian, Canizales-Quinteros, Samuel, Conomos, Matthew P., Deelman, Ewa, Do, Ron, Doheny, Kimberly, Fernández-Rhodes, Lindsay, Fornage, Myriam, Hailu, Benyam, Heiss, Gerardo, Henn, Brenna M., Hindorff, Lucia A., Jackson, Rebecca D., Laurie, Cecelia A., Laurie, Cathy C., Li, Yuqing, Lin, Dan-Yu, Moreno-Estrada, Andres, Nadkarni, Girish, Norman, Paul J., Pooler, Loreall C., Reiner, Alexander P., Romm, Jane, Sabatti, Chiara, Sandoval, Karla, Sheng, Xin, Stahl, Eli A., Stram, Daniel O., Thornton, Timothy A., Wassel, Christina L., Wilkens, Lynne R., Winkler, Cheryl A., Yoneyama, Sachi, Buyske, Steven, Haiman, Christopher A., Kooperberg, Charles, Le Marchand, Loic, Loos, Ruth J. F., Matise, Tara C., North, Kari E., Peters, Ulrike, Kenny, Eimear E., Carlson, Christopher S.

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Stroke genetics informs drug discovery and risk prediction across ancestries von Jürgenson, Tuuli, Namba, Shinichi, Posner, Daniel C., Kamanu, Frederick K., Koido, Masaru, He, Yunye, Caro, Ilana, Krebs, Kristi, Liaw, Yi-Ching, Parodi, Livia, Bae, Hee-Joon, Chong, Michael R., Tomppo, Liisa, Akinyemi, Rufus, Roshchupkin, Gennady V., Habib, Naomi, Jee, Yon Ho, Thomassen, Jesper Qvist, Abedi, Vida, Cárcel-Márquez, Jara, Nygaard, Marianne, Yonova-Doing, Ekaterina, Knol, Maria J., Lewis, Adam J., Judy, Renae L., Amouyel, Philippe, Bakker, Mark K., Bennett, David A., Bis, Joshua C., Bordes, Constance, Børte, Sigrid, Cain, Anael, Ridker, Paul M., Cho, Kelly, Chen, Zhengming, Cruchaga, Carlos, Cole, John W., de Cid, Rafael, Ferreira, Leslie E., He, Jing, Jeon, Christina E., Jern, Christina, Kamouchi, Masahiro, Keene, Keith L., Konuma, Takahiro, Kumar, Amit, Launer, Lenore J., Lee, Keon-Joo, Li, Jiang, Li, Liming, Manichaikul, Ani, Markus, Hugh S., Meitinger, Thomas, Mitchell, Braxton D., Morisaki, Takayuki, O’Donnell, Martin J., Onland-Moret, N. Charlotte, Ovbiagele, Bruce, Peters, Annette, Rosand, Jonathan, Sabatine, Marc S., Sacco, Ralph L., Saleheen, Danish, Schmidt, Carsten O., Smith, Nicholas L., Sloane, Kelly L., Sutoh, Yoichi, Tiwari, Hemant K., Wennberg, Patrik, Wilson, Peter W. F., Yang, Qiong, Yoon, Kyungheon, Gieger, Christian, Ninomiya, Toshiharu, Grabe, Hans J., Jukema, J. Wouter, Kim, Young Jin, Chen, Pei-Hsin, Mayerhofer, Ernst, Ikram, Mohammad A., Worrall, Bradford B., Lathrop, G. Mark, Riaz, Moeen, Simonsick, Eleanor M., Kõrv, Janika, Zand, Ramin, Prasad, Kameshwar, Frikke-Schmidt, Ruth, Liman, Thomas, Ruigrok, Ynte M., Bastarache, Lisa, Damrauer, Scott M., Rotter, Jerome I., Niiranen, Teemu J., Walters, Robin G., Owolabi, Mayowa O., Huffman, Jennifer E., Kamatani, Yoichiro, Dichgans, Martin, Debette, Stephanie

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Serum concentrations of per- and polyfluoroalkyl substances and risk of renal cell carcinoma in the Multiethnic Cohort Study von Rhee, Jongeun, Chang, Vicky C., Cheng, Iona, Calafat, Antonia M., Botelho, Julianne Cook, Shearer, Joseph J., Sampson, Joshua N., Setiawan, Veronica Wendy, Wilkens, Lynne R., Silverman, Debra T., Purdue, Mark P., Hofmann, Jonathan N.

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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation von Kitajima, Hidetoshi, Kim, Young Jin, Horikoshi, Momoko, Moon, Sanghoon, Robertson, Neil R., Nano, Jana, Lamri, Amel, Nakatochi, Masahiro, Graff, Mariaelisa, Yao, Jie, Bielak, Lawrence F., Hai, Yang, Schmidt, Ellen M., Nousome, Darryl, Trompet, Stella, Ahmad, Meraj, Noordam, Raymond, Lim, Victor J. Y., Joo, Yoonjung Yoonie, Prins, Bram Peter, Chen, Guanjie, Jensen, Richard A., Kabagambe, Edmond K., Xiang, Anny H., Flanagan, Jack, Adair, Linda S., Akiyama, Masato, Bertoni, Alain, Chee, Miao-Li, Chen, Shyh-Huei, Chen, Yuan-Tsong, Das, Swapan K., de Silva, H. Janaka, Eckardt, Kai-Uwe, Evans, Daniel S., Evans, Michele K., Franco, Oscar H., Fuchsberger, Christian, Genter, Pauline, Goodarzi, Mark O., Gordon-Larsen, Penny, Gorkin, David, Guo, Yu, Howard, Annie-Green, Hung, Yi-Jen, Hwang, Mi Yeong, Ingelsson, Martin, Jonas, Jost B., Jørgensen, Torben, Kamatani, Yoichiro, Kasturiratne, Anuradhani, Katsuya, Tomohiro, Keaton, Jacob M., Kho, Abel N., Khor, Chiea-Chuen, Läll, Kristi, Li-Gao, Ruifang, Liu, Jianjun, Luan, Jian’an, Luo, Xi, Lyssenko, Valeriya, Metspalu, Andres, Morris, Andrew D., Nalls, Michael A., Ntalla, Ioanna, Sattar, Naveed, Shi, Jinxiu, Shriner, Daniel, Stilp, Adrienne M., Takahashi, Atsushi, Taylor, Kent D., Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Varma, Rohit, Yamamoto, Ken, Yoon, Kyungheon, Yusuf, Salim, Zheng, Wei, Cho, Yoon Shin, Lind, Lars, Province, Michael A., Zonderman, Alan B., Becker, Diane M., Yokota, Mitsuhiro, Chen, Yii-Der Ida, Ma, Ronald C. W., Chandak, Giriraj R., Sale, Michèle M., Shu, Xiao-Ou, Jukema, J. Wouter, McKean-Cowdin, Roberta, Kooner, Jaspal S., North, Kari E., Florez, Jose C., Maeda, Shiro, Stefansson, Kari, Mohlke, Karen L., Gloyn, Anna L., Below, Jennifer E., Rotter, Jerome I.

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Tobacco Smoking and Risk of Second Primary Lung Cancer von Aredo, Jacqueline V., Luo, Sophia J., Gardner, Rebecca M., Sanyal, Nilotpal, Choi, Eunji, Hickey, Thomas P., Riley, Thomas L., Huang, Wen-Yi, Kurian, Allison W., Leung, Ann N., Wilkens, Lynne R., Robbins, Hilary A., Riboli, Elio, Kaaks, Rudolf, Tjønneland, Anne, Vermeulen, Roel C.H., Panico, Salvatore, Le Marchand, Loïc, Amos, Christopher I., Hung, Rayjean J., Freedman, Neal D., Johansson, Mattias, Cheng, Iona, Wakelee, Heather A., Han, Summer S.

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