A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia von Zeng, Andy G. X., Bansal, Suraj, Jin, Liqing, Mitchell, Amanda, Chen, Weihsu Claire, Abbas, Hussein A., Chan-Seng-Yue, Michelle, Voisin, Veronique, van Galen, Peter, Tierens, Anne, Cheok, Meyling, Preudhomme, Claude, Dombret, Hervé, Daver, Naval, Futreal, P. Andrew, Minden, Mark D., Kennedy, James A., Wang, Jean C. Y., Dick, John E.

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Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia von Schenk, Tino, Chen, Weihsu Claire, Göllner, Stefanie, Howell, Louise, Jin, Liqing, Hebestreit, Katja, Klein, Hans-Ulrich, Popescu, Andreea C, Burnett, Alan, Mills, Ken, Casero, Robert A, Marton, Laurence, Woster, Patrick, Minden, Mark D, Dugas, Martin, Wang, Jean C Y, Dick, John E, Müller-Tidow, Carsten, Petrie, Kevin, Zelent, Arthur

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Immune responses of therapeutic lipid nanoparticles von Chen, Weihsu Claire, May, Jonathan P., Li, Shyh-Dar

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Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia von Shlush, Liran I., Zandi, Sasan, Mitchell, Amanda, Chen, Weihsu Claire, Brandwein, Joseph M., Gupta, Vikas, Kennedy, James A., Schimmer, Aaron D., Schuh, Andre C., Yee, Karen W., McLeod, Jessica L., Doedens, Monica, Medeiros, Jessie J. F., Marke, Rene, Kim, Hyeoung Joon, Lee, Kwon, McPherson, John D., Hudson, Thomas J., Pan-Leukemia Gene Panel Consortium, The HALT, Brown, Andrew M. K., Yousif, Fouad, Trinh, Quang M., Stein, Lincoln D., Minden, Mark D., Wang, Jean C. Y., Dick, John E.

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A Simple and Improved Active Loading Method to Efficiently Encapsulate Staurosporine into Lipid-Based Nanoparticles for Enhanced Therapy of Multidrug Resistant Cancer von Tang, Wei-Lun, Chen, Weihsu Claire, Roy, Aniruddha, Undzys, Elijus, Li, Shyh-Dar

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Development of a Rapidly Dissolvable Oral Pediatric Formulation for Mefloquine Using Liposomes von Tang, Wei-Lun, Tang, Wei-Hsin, Chen, Weihsu Claire, Diako, Charles, Ross, Carolyn F, Li, Shyh-Dar

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Efficacy and Safety of Allogeneic Double Negative T Cell As a Cellular Therapy for AML and Its Underlying Mechanism von Lee, Jong Bok, Chen, Weihsu Claire, Streck, Elena, Kang, Sohyeong, Minden, Mark D., Dick, John E., Zhang, Li

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Nuclear Export Inhibitor KPT-8602 Is Highly Active Against Leukemic Blasts and Leukemia-Initiating Cells in Patient-Derived Xenograft Models of AML von Etchin, Julia, Berezovskaya, Alla, Saur Conway, Amy, Chen, Weihsu Claire, Baloglu, Erkan, Landesman, Yosef, Senapedis, William, Ellis, Joel, McCauley, Dilara, Stone, Richard M., Galinsky, Ilene, DeAngelo, Daniel J., Kauffman, Michael, Shacham, Sharon, Wang, Jean C.Y., Look, A. Thomas

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Abstract A176: Efficacy and safety of allogeneic double negative T cell as anti-AML therapy and its underlying mechanism von Lee, Jong Bok, Chen, Claire Weihsu, Minden, Mark D., Dick, John E., Zhang, Li

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Engraftment Patterns in NOD.SCID Mice Predict Outcome in Human AML von Kennedy, James A., Mitchell, Amanda, Chen, Weihsu Claire, Jin, Liqing, Ng, Stanley Wai-Kwong, Shlush, Liran I., Zandi, Sasan, McLeod, Jessica, Popescu, Andreea C., Mbong, Nathan, Arruda, Andrea, Minden, Mark D, Dick, John E., Wang, Jean C.Y.

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Leukemic Engraftment In NOD.SCID Mice Is Correlated With Clinical Parameters and Predicts Outcome In Human AML von Kennedy, James A., Mitchell, Amanda, Chen, Weihsu Claire, McLeod, Jessica, Popescu, Andreea C., Arruda, Andrea, Minden, Mark D., Dick, John E., Wang, Jean C.Y.

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Abstract 2914: Phosphoproteomic and transcriptional biomarkers predict response to SAR302503, a JAK2 inhibitor, in human acute myeloid leukemia preclinical models von Chen, Weihsu Claire, Yuan, Julie S., Mbong, Nathan, Popescu, Andreea C., Xing, Yan, Gerhard, Gitte, Zhang, Wei, Ma, Yussanne, Moore, Richard, Marra, Marco, Minden, Mark D., Hogge, Donna E., Guidos, Cynthia, Dick, John E., Wang, Jean C.Y.

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620. Liposome-Based Therapeutic Vaccine for Cervical Cancer von Chen, Weihsu Claire, Huang, Leaf

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Identification of pre-leukemic hematopoietic stem cells in acute leukemia von Shlush, Liran I., Zandi, Sasan, Mitchell, Amanda, Chen, Weihsu Claire, Brandwein, Joseph M., Gupta, Vikas, Kennedy, James A., Schimmer, Aaron D., Schuh, Andre C., Yee, Karen W., McLeod, Jessica L., Doedens, Monica, Medeiros, Jessie J.F., Marke, Rene, Kim, Hyeoung Joon, Lee, Kwon, McPherson, John D., Hudson, Thomas J., Brown, Andrew M.K., Trinh, Quang M., Stein, Lincoln D., Minden, Mark D., Wang, Jean C.Y., Dick, John E.

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Efficacy of SAR302503, a JAK2 Inhibitor, in the Treatment of a Primary Xenograft Model of Human Acute Myeloid Leukemia von Chen, Weihsu Claire, Popescu, Andreea C., Xing, Yan, Gerhard, Gitte, Yuan, Julie S., Minden, Mark D., Guidos, Cynthia, Hogge, Donna E., Wang, Jean C.Y., Dick, John E.

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DNMT3a Mutations Define a Pre-Leukemic Stem Cell Reservoir In Human Acute Myeloid Leukemia von Shlush, Liran I., Zandi, Sasan, Mitchell, Amanda, Chen, Weihsu Claire, Jessica, McLeod, Doedens, Monica, Jessie, Medeiros, Rene, Marke, John, McPherson J, Hudson, Thomas J, Andrew, Brown, Quang, Trinh M, Stein, Lincoln D, Kennedy, James A., Minden, Mark D., Wang, Jean C.Y., Dick, John E

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Mir-126 Governs Human Leukemia Stem Cell Quiescence and Chemotherapy Resistance von Lechman, Eric R., Gentner, Bernhard, van Galen, Peter, Wai-Kwong Ng, Stanley, Eppert, Kolja, Marke, Rene, Slush, Liran, Kennedy, James A., Mitchell, Amanda, Chen, Weihsu Claire, Voisin, Veronique, Bader, Gary, Minden, Mark D., Lu, Jun, Wang, Jean C.Y., Naldini, Luigi, Dick, John E.

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Corrigendum: identification of pre-leukaemic haematopoietic stem cells in acute leukaemia von Shlush, Liran I, Zandi, Sasan, Mitchell, Amanda, Chen, Weihsu Claire, Brandwein, Joseph M, Gupta, Vikas, Kennedy, James A, Schimmer, Aaron D, Schuh, Andre C, Yee, Karen W, McLeod, Jessica L, Doedens, Monica, Medeiros, Jessie J.F, Marke, Rene, Kim, Hyeoung Joon, Lee, Kwon, McPherson, John D, Hudson, Thomas J, Consortium, Pan-Leukemia Gene Panel, Brown, Andrew M.K, Yousif, Fouad, Trinh, Quang M, Stein, Lincoln D, Minden, Mark D, Wang, Jean C.Y, Dick, John E

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Identification of pre-leukaemic haematopoieticstemcells in acuteleukaemia von Shlush, Liran I, Zandi, Sasan, Mitchell, Amanda, Chen, Weihsu Claire, Brandwein, Joseph M, Gupta, Vikas, Kennedy, James A, Schimmer, Aaron D, Schuh, Andre C, Yee, Karen W, McLeod, Jessica L, Doedens, Monica, Medeiros, Jessie J F, Marke, Rene, Kim, Hyeoung Joon, Lee, Kwon, McPherson, John D, Hudson, Thomas J, Brown, Andrew M K, Trinh, Quang M, Stein, Lincoln D, Minden, Mark D, Wang, Jean C Y, Dick, John E

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Correction: Corrigendum: Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia von Shlush, Liran I., Zandi, Sasan, Mitchell, Amanda, Chen, Weihsu Claire, Brandwein, Joseph M., Gupta, Vikas, Kennedy, James A., Schimmer, Aaron D., Schuh, Andre C., Yee, Karen W., McLeod, Jessica L., Doedens, Monica, Medeiros, Jessie J. F., Marke, Rene, Kim, Hyeoung Joon, Lee, Kwon, McPherson, John D., Hudson, Thomas J., Pan-Leukemia Gene Panel Consortium, The HALT, Brown, Andrew M. K., Yousif, Fouad, Trinh, Quang M., Stein, Lincoln D., Minden, Mark D., Wang, Jean C. Y., Dick, John E.

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