CSF3R T618I Collaborates With RUNX1‐RUNX1T1 to Expand Hematopoietic Progenitors and Sensitizes to GLI Inhibition von Swoboda, Anja S., Arfelli, Vanessa C., Danese, Anna, Windisch, Roland, Kerbs, Paul, Redondo Monte, Enric, Bagnoli, Johannes W., Chen‐Wichmann, Linping, Caroleo, Alessandra, Cusan, Monica, Krebs, Stefan, Blum, Helmut, Sterr, Michael, Enard, Wolfgang, Herold, Tobias, Colomé‐Tatché, Maria, Wichmann, Christian, Greif, Philipp A.

Volltext

Hyperinflammation in patients with chronic granulomatous disease leads to impairment of hematopoietic stem cell functions von Weisser, Maren, PhD, Demel, Uta M., MSc, Stein, Stefan, PhD, Chen-Wichmann, Linping, PhD, Touzot, Fabien, MD, PhD, Santilli, Giorgia, PhD, Sujer, Stefanie, MSc, Brendel, Christian, PhD, Siler, Ulrich, PhD, Cavazzana, Marina, MD, PhD, Thrasher, Adrian J., MD, PhD, Reichenbach, Janine, MD, Essers, Marieke A.G., PhD, Schwäble, Joachim, MD, Grez, Manuel, PhD

Volltext

Alpharetroviral Vector-mediated Gene Therapy for X-CGD: Functional Correction and Lack of Aberrant Splicing von Kaufmann, Kerstin B., Brendel, Christian, Suerth, Julia D., Mueller-Kuller, Uta, Chen-Wichmann, Linping, Schwäble, Joachim, Pahujani, Shweta, Kunkel, Hana, Schambach, Axel, Baum, Christopher, Grez, Manuel

Volltext

The truncated RUNX1/ETO activates VLA-4-dependent adhesion and migration of hematopoietic progenitor cells von Ponnusamy, Kanagaraju, Chen-Wichmann, Linping, Kuvardina, Olga N, Lausen, Jörn, Henschler, Reinhard, Wichmann, Christian

Volltext

Dimer-tetramer transition controls RUNX1/ETO leukemogenic activity von Wichmann, Christian, Becker, Yvonne, Chen-Wichmann, Linping, Vogel, Vitali, Vojtkova, Anna, Herglotz, Julia, Moore, Sandra, Koch, Joachim, Lausen, Jörn, Mäntele, Werner, Gohlke, Holger, Grez, Manuel

Volltext

CSF3R T618I Collaborates with RUNX1-RUNX1T1 to Expand Human Haematopoietic Stem and Progenitor Cells von Swoboda, Anja, Windisch, Roland, Kerbs, Paul, Redondo Monte, Enric, Bagnoli, Johannes W., Chen-Wichmann, Linping, Caroleo, Alessandra, Cusan, Monica, Enard, Wolfgang, Herold, Tobias, Wichmann, Christian, Greif, Philipp A.

Volltext

Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes von Windisch, Roland, Soliman, Sarah, Hoffmann, Adrian, Chen-Wichmann, Linping, Danese, Anna, Vosberg, Sebastian, Bravo, Jimena, Lutz, Sebastian, Kellner, Christian, Fischer, Alexander, Gebhard, Claudia, Redondo Monte, Enric, Hartmann, Luise, Schneider, Stephanie, Beier, Fabian, Strobl, Carolin Dorothea, Weigert, Oliver, Peipp, Matthias, Schündeln, Michael, Stricker, Stefan H, Rehli, Michael, Bernhagen, Jürgen, Humpe, Andreas, Klump, Hannes, Brendel, Christian, Krause, Daniela S, Greif, Philipp A, Wichmann, Christian

Volltext

Oncogenic Deregulation of Cell Adhesion Molecules in Leukemia von Windisch, Roland, Pirschtat, Nina, Kellner, Christian, Chen-Wichmann, Linping, Lausen, Jörn, Humpe, Andreas, Krause, Daniela S, Wichmann, Christian

Volltext

Efficient Chimeric Antigen Receptor T-Cell Generation Starting with Leukoreduction System Chambers of Thrombocyte Apheresis Sets von Xhaxho, Stefani, Chen-Wichmann, Linping, Kreissig, Sophie, Windisch, Roland, Gottschlich, Adrian, Nandi, Sayantan, Schabernack, Sophie, Kohler, Irmgard, Kellner, Christian, Kobold, Sebastian, Humpe, Andreas, Wichmann, Christian

Volltext

ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells von Redondo Monte, Enric, Wilding, Anja, Leubolt, Georg, Kerbs, Paul, Bagnoli, Johannes W., Hartmann, Luise, Hiddemann, Wolfgang, Chen-Wichmann, Linping, Krebs, Stefan, Blum, Helmut, Cusan, Monica, Vick, Binje, Jeremias, Irmela, Enard, Wolfgang, Theurich, Sebastian, Wichmann, Christian, Greif, Philipp A.

Volltext

An Inducible Leukemia-Associated Transcription Factor Facilitates Large-Scale Ex Vivo Generation of Functional Human Macrophages von Windisch, Roland, Soliman, Sarah, Hoffmann, Adrian, Chen-Wichmann, Linping, Lutz, Sebastian, Kellner, Christian, Redondo Monte, Enric, Vosberg, Sebastian, Hartmann, Luise, Schneider, Stephanie, Beier, Fabian, Strobl, Carolin Dorothea, Weigert, Oliver, Peipp, Matthias, Schündeln, Michael, Bernhagen, Jürgen, Humpe, Andreas, Brendel, Christian, Klump, Hannes, Greif, Philipp A., Wichmann, Christian

Volltext

Specific effects of somatic GATA2 zinc finger mutations on erythroid differentiation von Redondo Monte, Enric, Leubolt, Georg, Windisch, Roland, Kerbs, Paul, Dutta, Sayantanee, Landspersky, Theresa, Istvánffy, Rouzanna, Oostendorp, Robert A.J., Chen-Wichmann, Linping, Herold, Tobias, Cusan, Monica, Schotta, Gunnar, Wichmann, Christian, Greif, Philipp A.

Volltext

Compatibility of RUNX1/ETO fusion protein modules driving CD34+ human progenitor cell expansion von Chen-Wichmann, Linping, Shvartsman, Marina, Preiss, Caro, Hockings, Colin, Windisch, Roland, Redondo Monte, Enric, Leubolt, Georg, Spiekermann, Karsten, Lausen, Jörn, Brendel, Christian, Grez, Manuel, Greif, Philipp A., Wichmann, Christian

Volltext

CD133-targeted Gene Transfer Into Long-term Repopulating Hematopoietic Stem Cells von Brendel, Christian, Goebel, Benjamin, Daniela, Abriss, Brugman, Martijn, Kneissl, Sabrina, Schwäble, Joachim, Kaufmann, Kerstin B, Müller-Kuller, Uta, Kunkel, Hana, Chen-Wichmann, Linping, Abel, Tobias, Serve, Hubert, Bystrykh, Leonid, Buchholz, Christian J, Grez, Manuel

Volltext

Disturbed Endothelial Blood-Bone Marrow-Barrier In Nox4 Deficient Mice von Weisser, Maren, Kaufmann, Kerstin B., Itkin, Tomer, Chen-Wichmann, Linping, Lapidot, Tsvee, Grez, Manuel

Volltext

CSF3R T618I Collaborates With RUNX1‐RUNX1T1 to Expand Hematopoietic Progenitors and Sensitizes to GLI Inhibition von Swoboda, Anja S., Arfelli, Vanessa C., Danese, Anna, Windisch, Roland, Kerbs, Paul, Redondo Monte, Enric, Bagnoli, Johannes W., Chen‐Wichmann, Linping, Caroleo, Alessandra, Cusan, Monica, Krebs, Stefan, Blum, Helmut, Sterr, Michael, Enard, Wolfgang, Herold, Tobias, Colomé‐Tatché, Maria, Wichmann, Christian, Greif, Philipp A.

Volltext

Hyperinflammation in patients with chronic granulomatous disease leads to impairment of hematopoietic stem cell functions von Weisser, Maren, Demel, Uta M, Stein, Stefan, Chen-Wichmann, Linping, Touzot, Fabien, Santilli, Giorgia, Sujer, Stefanie, Brendel, Christian, Siler, Ulrich, Cavazzana, Marina, Thrasher, Adrian J, Reichenbach, Janine, Essers, Marieke A G, Schwäble, Joachim, Grez, Manuel

Volltext

Aberrant epigenetic regulators control expansion of human CD34+ hematopoietic stem/progenitor cells von Faridi, Farnaz, Ponnusamy, Kanagaraju, Quagliano-Lo Coco, Isabell, Chen-Wichmann, Linping, Grez, Manuel, Henschler, Reinhard, Wichmann, Christian

Volltext

Human miR223 promoter as a novel myelo-specific promoter for chronic granulomatous disease gene therapy von Brendel, Christian, Hänseler, Walther, Wohlgensinger, Vital, Bianchi, Matteo, Tokmak, Serap, Chen-Wichmann, Linping, Kuzmenko, Elena, Cesarovic, Nikola, Nicholls, Flora, Reichenbach, Janine, Seger, Reinhard, Grez, Manuel, Siler, Ulrich

Volltext

From bench to bedside: preclinical evaluation of a self-inactivating gammaretroviral vector for the gene therapy of X-linked chronic granulomatous disease von Stein, Stefan, Scholz, Simone, Schwäble, Joachim, Sadat, Mohammed A, Modlich, Ute, Schultze-Strasser, Stephan, Diaz, Margarita, Chen-Wichmann, Linping, Müller-Kuller, Uta, Brendel, Christian, Fronza, Raffaele, Kaufmann, Kerstin B, Naundorf, Sonja, Pech, Nancy K, Travers, Jeffrey B, Matute, Juan D, Presson, Jr, Robert G, Sandusky, George E, Kunkel, Hana, Rudolf, Eva, Dillmann, Adelina, von Kalle, Christof, Kühlcke, Klaus, Baum, Christopher, Schambach, Axel, Dinauer, Mary C, Schmidt, Manfred, Grez, Manuel

Volltext